acosamine has been researched along with rhodomycinone* in 1 studies
1 other study(ies) available for acosamine and rhodomycinone
| Article | Year |
|---|---|
A short and efficient transformation of rhamnose into activated daunosamine, acosamine, ristosamine and epi-daunosamine derivatives, and synthesis of an anthracycline antibiotic acosaminyl-epsilon-iso-rhodomycinone.
3-Amino-2,3,6-trideoxyhexopyranoses are essential constituents of most anthracycline antitumour antibiotics. For an investigation of structure-activity relationships, the four diastereomeric amino sugars daunosamine, acosamine, ristosamine, and epi-daunosamine were synthesised in short and efficient routes starting from commercially available rhamnose. Several glycosyl donors were provided and their use was exemplified in the synthesis of acosaminyl-epsilon-isorhodomycinone. Topics: Anthracyclines; Antibiotics, Antineoplastic; Doxorubicin; Drug Screening Assays, Antitumor; Hexosamines; Humans; Molecular Structure; Rhamnose; Stereoisomerism; Tumor Cells, Cultured | 2000 |