acosamine and rhodomycinone

acosamine has been researched along with rhodomycinone* in 1 studies

Other Studies

1 other study(ies) available for acosamine and rhodomycinone

ArticleYear
A short and efficient transformation of rhamnose into activated daunosamine, acosamine, ristosamine and epi-daunosamine derivatives, and synthesis of an anthracycline antibiotic acosaminyl-epsilon-iso-rhodomycinone.
    Carbohydrate research, 2000, Dec-01, Volume: 329, Issue:4

    3-Amino-2,3,6-trideoxyhexopyranoses are essential constituents of most anthracycline antitumour antibiotics. For an investigation of structure-activity relationships, the four diastereomeric amino sugars daunosamine, acosamine, ristosamine, and epi-daunosamine were synthesised in short and efficient routes starting from commercially available rhamnose. Several glycosyl donors were provided and their use was exemplified in the synthesis of acosaminyl-epsilon-isorhodomycinone.

    Topics: Anthracyclines; Antibiotics, Antineoplastic; Doxorubicin; Drug Screening Assays, Antitumor; Hexosamines; Humans; Molecular Structure; Rhamnose; Stereoisomerism; Tumor Cells, Cultured

2000