Page last updated: 2024-09-04

aclacinomycin and cytarabine

aclacinomycin has been researched along with cytarabine in 24 studies

Compound Research Comparison

Studies (aclacinomycin)	Trials (aclacinomycin)	Recent Studies (post-2010) (aclacinomycin)	Studies (cytarabine)	Trials (cytarabine)	Recent Studies (post-2010) (cytarabine)
168	8	21	15,487	2,424	3,188

Protein Interaction Comparison

Protein	Taxonomy	aclacinomycin (IC50)	cytarabine (IC50)
nuclear receptor coactivator 3 isoform a	Homo sapiens (human)		7.533
E3 ubiquitin-protein ligase Mdm2	Homo sapiens (human)		0.02

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (50.00)	18.7374
1990's	1 (4.17)	18.2507
2000's	1 (4.17)	29.6817
2010's	6 (25.00)	24.3611
2020's	4 (16.67)	2.80

Authors

Authors	Studies
Kanai, M; Kanno, M; Kobayashi, K; Kondo, K; Matano, S; Matsuda, T; Nakamura, S; Ohtake, S; Okafuji, K; Yoshida, T	1
Ishikawa, I; Kaneko, H; Katoh, M; Kojima, N; Shirai, T; Umeda, M; Yamaguchi, R; Yamauchi, M	1
Krc, I; Mlcochová, E; Myslivecek, M	1
Ishii, E; Kato, Y; Matsuzaki, A; Miyazaki, S; Ueda, K	1
Ehninger, G; Freund, M; Heil, G; Hoelzer, D; Kurrle, E; Link, H; Mitrou, PS	1
Fink, FM; Gadner, H; Grümayer, ER; Kardos, G; Revesz, T; Schuler, D	1
Hibi, S; Imashuku, S; Morimoto, S; Morioka, Y; Nakajima, T; Sugimoto, T; Todo, S	1
Lutz, D	1
Ito, K; Kobayashi, K; Matsuda, T; Nakagoshi, T; Nakamura, E; Nakamura, S; Nakanishi, J; Natori, K; Ohtake, S; Yoshida, T	1
Kawamura, S; Maekawa, I; Miyake, T; Sasaki, H	1
Yamada, K	1
Kobayashi, M; Tahara, T	1
Abe, Y; Hatanaka, T; Ito, T; Kamiya, O; Nagata, K; Ohara, K; Ono, Y; Saito, M	1
Meng, XL	1
Chang, CK; He, Q; Li, X; Song, LX; Wu, LY; Xu, L; Zhang, QX; Zhang, Y	1
Chen, L; Mi, R; Wei, X; Yin, Q	1
Cao, XM; Chen, YX; Gu, LF; He, AL; Lei, B; Liu, J; Ma, XR; Wang, FX; Wang, J; Wang, JL; Xu, Y; Yang, Y; Zhang, PY; Zhang, WG; Zhao, WH	1
Cao, YB; DA, WM; Li, SW; Li, XH; Liu, B; Liu, ZY; Wu, XX; Wu, YM; Xu, LX; Yan, B; Yang, XL	1
Fan, C; Huang, J; Jin, J; Mai, W; Mao, L; Meng, H; Qian, W; Suo, S; Tong, H; Yu, W	1
Hu, C; Jin, J; Lin, P; Lou, Y; Luo, Y; Ma, L; Mai, W; Mei, C; Meng, H; Qian, J; Qian, W; Ren, Y; Tong, H; Wei, J; Xie, L; Xu, G; Xu, W; Ye, L; Ye, X; Zhou, X	1
Bian, Y; Huang, C; Ma, S; Ma, W; Miao, L; Miao, M; Xia, F; Yu, D	1
Jin, J; Li, J; Yu, W; Zhang, X	1
Bo, J; Dou, L; Gao, C; Gao, X; Li, H; Liu, D; Lu, N; Wang, L; Wei, Y; Wu, Y; Zhang, R; Zhu, C	1
Chang, J; Jin, J; Shen, YJ; Wang, HF; Ye, XN; Zhang, Y; Zhu, HH; Zhu, L	1

Trials

3 trial(s) available for aclacinomycin and cytarabine

Article	Year
[New agents in the treatment of leukemia and lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 2 Topics: Aclarubicin; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Lymphoma; Middle Aged; Naphthacenes	1983
Clinical outcome of treatment with a combined regimen of decitabine and aclacinomycin/cytarabine for patients with refractory acute myeloid leukemia. Annals of hematology, 2012, Volume: 91, Issue:12 Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Survival; Cyclin-Dependent Kinase Inhibitor p15; Cytarabine; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Middle Aged; Recurrence; Remission Induction; Survival Analysis; Tumor Cells, Cultured; Young Adult	2012
A phase II study of chidamide, cytarabine, aclarubicin, granulocyte colony-stimulating factor, and donor lymphocyte infusion for relapsed acute myeloid leukemia and myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation. Medical oncology (Northwood, London, England), 2023, Jan-10, Volume: 40, Issue:2 Topics: Aclarubicin; Adult; Cytarabine; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Myelodysplastic Syndromes; Recurrence	2023

Other Studies

21 other study(ies) available for aclacinomycin and cytarabine

Article	Year
Salvage chemotherapy of refractory non-Hodgkin's lymphoma with aclacinomycin, behenoyl ara-C, etoposide, and prednisolone. Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:2 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Humans; Lymphoma, Non-Hodgkin; Neoplasm Recurrence, Local; Prednisolone; Remission Induction; Time Factors	1989
[The effect of antileukemic drugs on superoxide (O2-) production by human neutrophils]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:11 Topics: Aclarubicin; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Naphthacenes; Neutrophils; Superoxides	1987
Combination therapy with aclacinomycin in acute leukemia. Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1986, Volume: 113 Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Naphthacenes; Thioguanine	1986
Treatment of juvenile chronic myelocytic leukemia with multidrug chemotherapy including aclacinomycin and N4-behenoyl-1-beta-D-arabinofuranosylcytosine. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1986, Volume: 49, Issue:6 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Humans; Leukemia, Myeloid; Male; Naphthacenes	1986
Age adapted induction and intensified consolidation therapy in acute myelogenous leukemia. Onkologie, 1986, Volume: 9, Issue:3 Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prognosis	1986
Aclacinomycin-A in the induction treatment of childhood AML. Onkologie, 1986, Volume: 9, Issue:3 Topics: Aclarubicin; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine	1986
[Treatment of a case of childhood acute non-lymphocytic leukemia (ANLL) using high-dose cytosine arabinoside for intensification of early therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2 Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Methotrexate; Naphthacenes; Vincristine	1987
[Various induction therapies in older patients with acute myeloid leukemias]. Wiener klinische Wochenschrift, 1985, Feb-01, Volume: 97, Issue:3 Topics: Aclarubicin; Adolescent; Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Tamoxifen	1985
[ABEP chemotherapy in the treatment of advanced non-Hodgkin's lymphomas]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1 Topics: Aclarubicin; Adult; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukopenia; Lymphoma; Male; Middle Aged; Naphthacenes; Prednisolone; Thrombocytopenia; Vincristine	1986
[Comparative evaluation of combined chemotherapeutic regimens in acute non-lymphocytic leukemia]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1983, Volume: 58, Issue:3 Topics: Aclarubicin; Acute Disease; Adult; Age Factors; Ancitabine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone	1983
[Adriamycin-aclacinomycin therapy (AA therapy) for acute leukemia unresponsive to BH-AC-DMP therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:6 Topics: Aclarubicin; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone	1983
[Short-term intensive consolidation chemotherapy in the treatment of acute nonlymphocytic leukemia]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2 Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vinblastine; Vincristine	1994
[Sensitivity of survivin-positive primary leukemia cells to chemotherapy]. Zhongguo shi yan xue ye xue za zhi, 2005, Volume: 13, Issue:2 Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Antineoplastic Agents; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Male; Microtubule-Associated Proteins; Middle Aged; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survivin; Tumor Cells, Cultured	2005
CHAG priming regimen containing of cytarabine, aclacinomycin homoharringtonine and G-CSF for relapsed refractory acute myelogenous leukemia: a modified combination chemotherapeutic combination. Leukemia & lymphoma, 2013, Volume: 54, Issue:10 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Treatment Outcome	2013
[Cohort Study on GHA and New Combined Priming Chemotherapeutic Regimens in Treatment of Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome]. Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:2 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; Cohort Studies; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Granulocytes; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Recurrence; Thrombocytopenia	2015
[Clinical Efficacy of Decitabine Combined with CAG Regimen for Myelodysplastic Syndrome-RAEB and Refractory Acute Myeloid Leukemia]. Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:4 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Karyotype; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pancytopenia; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome	2015
[Efficacy of HAA regimen in the treatment of 64 patients with refractory/relapsed acute myeloid leukemia]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:2 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate	2016
Decitabine priming prior to low-dose chemotherapy improves patient outcomes in myelodysplastic syndromes-RAEB: a retrospective analysis vs. chemotherapy alone. Journal of cancer research and clinical oncology, 2017, Volume: 143, Issue:5 Topics: Aclarubicin; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Idarubicin; Karyotype; Male; Middle Aged; Mutation; Retrospective Studies	2017
A retrospective study of the correlation of in vitro chemosensitivity using ATP-TCA with patient clinical outcomes in acute myeloid leukemia. Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:3 Topics: Aclarubicin; Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Young Adult	2020
Relapsed/refractory early T-cell precursor acute lymphoblastic leukemia was salvaged by venetoclax plus HAG regimen. Annals of hematology, 2020, Volume: 99, Issue:2 Topics: Aclarubicin; Adult; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Combined Modality Therapy; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Homoharringtonine; Humans; Male; Mutation; Neoplasm Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Sulfonamides	2020
CAG (cytarabine, aclarubicin and granulocyte colony-stimulating factor) regimen for core binding factor acute myeloid leukaemia with measurable residual disease. Annals of hematology, 2023, Volume: 102, Issue:7 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Neutropenia; Retrospective Studies; Treatment Outcome	2023