Page last updated: 2024-08-23

acitretin and etretinate

acitretin has been researched along with etretinate in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199043 (35.54)18.7374
1990's59 (48.76)18.2507
2000's13 (10.74)29.6817
2010's6 (4.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bohoslawec, O; Chan, KK; DeNoble, J; Gabriel, E; Han, RJ; Machlin, LJ; Pawson, BA; Piermattie, V; Specian, AC; Srisethnil, S; Trown, PW1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Christophersen, J; Danneskiold-Samsoe, P; Geiger, JM; Kragballe, K; Larsen, FG; Laurberg, G; Serup, J; Thomsen, K1
Bollag, W; Jablonska, S; Marczak, M; Szmurlo, A1
Bouvy, ML; Cornel, MC; De Jong-Van den Berg, LT; Stricker, BH; Sturkenboom, MC; Wesseling, H1
Fernandes, D; Klein, J; Koren, G; Pastuszak, A1
Chou, RC; Huselton, CA; Wiegand, UW; Wyss, R2
Brandt, R; Claudepierre, P; Meyer, J; Tillement, JP; Urien, S1
De Bersaques, J; De Leenheer, AP; Kint, AH; Lambert, WE; Meyer, E2
Fritsch, PO1
Lowe, N1
Edelson, RL; Gasparro, FP; Tokura, Y1
Jabłonska, S; Majewski, S; Makieła, B; Marczak, M; Rudnicka, L; Skiendzielewska, A; Skopinska, M; Szmurło, A1
Barendregt, M; Cornel, MC; de Jong-van den Berg, LT; de Smet, PA; Herings, RM; Stricker, BH1
Detmar, M; Imcke, E; Mayer-da Silva, A; Orfanos, CE; Ruszczak, Z1
Happle, R; Steijlen, PM; Van de Kerkhof, PC; van Dooren-Greebe, RJ1
Happle, R; Perret, CM; Ruiter, DJ; Schuurmans Stekhoven, JH; Steijlen, PM1
Bitterling, T; Gollnick, H; Orfanos, CE; Rinck, G1
De Bersaques, JP; De Leenheer, AP; Kint, AH; Lambert, WE1
Blouin, RA; McNamara, PJ1
Halioua, B; Saurat, JH1
O'Brien, TJ1
Agnish, ND; Dashman, T; DiNardo, B; Rusin, G; Vane, FM1
elAttar, TM; Lin, HS1
De Bersaques, JP; De Leenheer, AP; Kint, A; Lambert, WE1
Carillet, V; Dubertret, L; Hüppe, G; Mazière, JC; Morlière, P; Santus, R2
Löfberg, B; Nau, H; Reiners, J; Spielmann, H1
Berne, B; Rollman, O; Vahlquist, A1
Ehlert, R; Gollnick, H; Orfanos, CE; Rinck, G1
Hashimoto, Y; Iizuka, H; Ohkuma, N1
Pihl-Lundin, I; Rollman, O; Vahlquist, A1
Coble, BI; Dahlgren, C; Molin, L; Stendahl, O1
Geiger, JM; Lauharanta, J1
Oikarinen, A1
Meffert, H; Sönnichsen, N1
Bjerke, JR; Geiger, JM1
Jakobsen, P; Kragballe, K; Larsen, FG; Nielsen-Kudsk, F1
Bjerke, JR; Falk, ES; Geiger, JM; Gip, L; Hjorth, N; Jansén, CT; Kragballe, K; Lauharanta, J; Mork, NJ; Reunala, T1
Abita, JP; Balitrand, N; Chomienne, C1
Kingston, TP; Lowe, NJ; Matt, LH1
Jakobsen, P; Larsen, CG; Larsen, FG1
Jakobsen, P; Kragballe, K; Larsen, CG; Larsen, FG; Nielsen-Kudsk, F; Nørgaard, A1
Vahlquist, A1
Happle, R; Traupe, H; van de Kerkhof, PC1
Jakobsen, P; Kragballe, K; Larsen, CG; Larsen, FG; Nielsen-Kudsk, F1
Czarnetzki, BM; Geiger, JM1
Alfin-Slater, RB; Ashley, JM; Borok, ME; Lowe, NJ1
Harms, M; Masouyé, I; Saurat, JH1
Lazarus, V; Lowe, NJ; Matt, L1
Bauer, R; Brindley, C; Gollnick, H; Hoting, E; Orfanos, CE; Plewig, G; Wokalek, H1
Geiger, JM; Lassus, A1
Amblard, P; Beani, JC; Boulanger, A; Claudy, A; Frenk, E; Geiger, JM; Grosshans, E; Guilhou, JJ; Mérot, Y; Saurat, JH1
Geiger, JM; Ledo, A; Marrón, JM; Martín, M1
Thongnopnua, P; Zimmerman, CL1
Bucheli, F; Wyss, R1
Kochhar, DM; Kraft, JC; Löfberg, B; Nau, H; Reiners, J1
Gollnick, H; Orfanos, CE; Stadler, R; Tsambaos, D1
Gollnick, H; Orfanos, CE1
Kitano, Y; Nagase, N; Okada, N1
Band, P; Besner, JG; Leclaire, R; Mailhot, S; Meloche, S1
Dubertret, L; Lebreton, C; Touraine, R1
Lauharanta, J; Paravicini, U1
Bauer, R; Orfanos, CE1
Hamada, K; Kobayashi, K; Mori, M; Morita, E; Ninomiya, T; Okada, Y1
Rollman, O; Vahlquist, A1
Hirone, T; Ishizaki, H; Kaminaga, T; Kaseda, H; Masuda, H1
Annesley, T; Ellis, C; Giacherio, D; Grekin, R; Wilkerson, K1
DiGiovanna, JJ; Gantt, G; Gross, EG; McClean, SW; Peck, GL; Ruddel, ME1
Braun-Falco, O; Hein, R; Krieg, T; Mensing, H; Müller, PK1
Fujita, J; Yoshida, O1
Palmskog, G1
Aoyagi, T; Fukaya, T; Iizuka, H; Kamigaki, K; Kato, N; Miura, Y1
Decker, MA; Zimmerman, CL1
Arnold, A; Hirte, H; Kowaleski, B; Tozer, R1
Cornel, MC; de Jong-Van Den Berg, LT; Stricker, BH; Sturkenboom, MC; van Voorst-Vader, PC; Wesseling, H1
van de Kerkhof, PC; van Dooren-Greebe, RJ1
Larsen, FG1
Baudin, M; Geiger, JM; Saurat, JH1
Bun, H; de Sousa, G; Geiger, JM; Laugier, JP; Rahmani, R; Surber, C1
Burke, MD; Omar, G; Ormerod, AD; Shah, IA; Whiting, PH1
Bermann, D; Maibach, HI; Surber, C; Wilhelm, KP1
Frappaz, A; Larbre, B; Nicolas, JF; Thivolet, J1
Berbis, P; Chemila, JF; Hesse, S; Privat, Y1
Geiger, JM; Saurat, JH1
Jakobsen, P; Knudsen, J; Kragballe, K; Larsen, FG; Nielsen-Kudsk, F; Weismann, K1
Bergoend, H; Delaporte, E; Feingold, N; Janin, A; N'guyen-Mailfer, C; Piette, F; Savary, JB; Vasseur, F1
Almond-Roesler, B; Orfanos, CE1
Abbott, M; Chan, A; Hanna, M; Keane, RJ1
De Boo, T; Hangx, NM; Kuijpers, AL; Lemmens, JA; Van de Kerkhof, PC; Van Dooren-Greebe, RJ1
Atherton, DJ; Harper, JI; Lacour, M; Mehta-Nikhar, B1
Chou, RC; Dittrich, S; Saulnier, E; Schenk, P; Schmitt-Hoffmann, AH1
Hönigsmann, H; Maier, H2
Bleiker, TO; Bourke, JF; Graham-Brown, RA; Hutchinson, PE1
Goerz, G; Herrmann, G; Jungblut, RM1
Monga, M1
Katz, HI1
Chaidaroglou, A; Degiannis, D; Georgiou, S; Koniavitou, K; Tsambaos, D1
Chou, RC; Wiegand, UW1
Katz, HI; Leach, EE; Waalen, J1
Orfanos, CE1
Gasser, R; Klemisch, W; Knights, KM1
Brockhoff, PB; Grønhøj Larsen, F; Hjorter, A; Jakobsen, P; Nielsen-Kudsk, F; Steinkjer, B1
Barbaud, A; Schmutz, JL; Trechot, P1
Lebwohl, M; Maryles, S; Rozenblit, M1
Feldman, S; Koo, J; Lebwohl, M; Menter, A1
Bouwes Bavinck, JN; De Graaf, YG; Euvrard, S1
Fraunfelder, FT; Fraunfelder, FW1
Finlay, AY; Katugampola, RP1
Johnston, GA; Macbeth, AE1
Chan, SY; Ho, PC; Liu, X1
Huh, W; Kim, DW; Kim, HG; Kim, HK; Kim, JW; Kim, MH; Kim, YG; Lee, JH; Lee, SY; Park, HD; Youn, JI1
Chun, MR; Huh, WS; Kim, DW; Kim, HG; Kim, HK; Kim, JW; Kim, MH; Kim, YG; Lee, JH; Lee, SY; Park, HD; Youn, JI1
Campo-Paysaa, F; Gutierrez-Mazariegos, J; Schubert, M; Theodosiou, M1
Kim, CH; Lee, SW; Shin, JY; Shin, SY; Shin, YH1
Cassano, N; Vena, GA1
Davis, SA; Feldman, SR; Yentzer, BA1

Reviews

24 review(s) available for acitretin and etretinate

ArticleYear
Acitretin (Neotigason). A review of pharmacokinetics and teratogenicity and hypothesis on metabolic pathways.
    Pharmaceutisch weekblad. Scientific edition, 1992, Apr-24, Volume: 14, Issue:2

    Topics: Abnormalities, Drug-Induced; Acitretin; Animals; Biotransformation; Etretinate; Humans; Tretinoin

1992
Retinoids in psoriasis and disorders of keratinization.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:6 Pt 2

    Topics: Acitretin; Etretinate; Humans; Ichthyosis; Keratosis; Psoriasis

1992
Risk: benefit ratio in the treatment of psoriasis with systemic retinoids.
    The British journal of dermatology, 1990, Volume: 122 Suppl 36

    Topics: Abnormalities, Drug-Induced; Acitretin; Adult; Aged; Bone Diseases; Chemical and Drug Induced Liver Injury; Etretinate; Eye Diseases; Female; Humans; Lipids; Male; Middle Aged; Psoriasis; Risk Factors; Skin Diseases; Tretinoin

1990
Retinoids: an overview of pharmacokinetics and therapeutic value.
    Methods in enzymology, 1990, Volume: 190

    Topics: Acitretin; Animals; Etretinate; Humans; Isotretinoin; Retinoids; Tretinoin

1990
Retinoids in disorders of keratinization: their use in adults.
    Dermatologica, 1987, Volume: 175 Suppl 1

    Topics: Acitretin; Adult; Etretinate; Humans; Ichthyosis; Keratoderma, Palmoplantar; Keratosis; Pityriasis; Tretinoin

1987
Systemic retinoid therapy for psoriasis.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:1 Pt 2

    Topics: Acitretin; Etretinate; Humans; Isomerism; Isotretinoin; Psoriasis; Tretinoin

1988
Current developments of oral retinoid therapy with three generations of drugs. Non-aromatic, monoaromatic and polyaromatic retinoids (arotinoids).
    Current problems in dermatology, 1985, Volume: 13

    Topics: Acitretin; Administration, Oral; Benzoates; Eczema; Etretinate; Humans; Isotretinoin; Psoriasis; Retinoids; Skin Diseases; Skin Diseases, Vesiculobullous; Tretinoin

1985
Evidence for anti-inflammatory activities of oral synthetic retinoids: experimental findings and clinical experience.
    The British journal of dermatology, 1983, Volume: 109 Suppl 25

    Topics: Acitretin; Administration, Oral; Animals; Anti-Inflammatory Agents; Etretinate; Granulocytes; Humans; Isotretinoin; Leukocyte Count; Lymphocytes; Macrophages; Mice; Psoriasis; Skin Diseases; Skin Temperature; Tretinoin

1983
The arotinoids: early clinical experience and discussion of future development.
    Leukemia, 1994, Volume: 8 Suppl 3

    Topics: Acitretin; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Etretinate; Humans; Morpholines; Retinoids

1994
Pharmacokinetics of etretinate and acitretin with special reference to treatment of psoriasis.
    Acta dermato-venereologica. Supplementum, 1994, Volume: 190

    Topics: Absorption; Acitretin; Etretinate; Humans; Methotrexate; Psoriasis; Vitamin A

1994
Teratogenic risk with etretinate and acitretin treatment.
    Dermatology (Basel, Switzerland), 1994, Volume: 189, Issue:2

    Topics: Abnormalities, Drug-Induced; Acitretin; Adolescent; Adult; Animals; Contraceptives, Oral; Dose-Response Relationship, Drug; Etretinate; Female; Fetal Diseases; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reproducibility of Results; Risk Factors

1994
Acitretin and etretinate. How and when they should be used.
    Dermatologic clinics, 1993, Volume: 11, Issue:1

    Topics: Acitretin; Algorithms; Clinical Protocols; Drug Interactions; Drug Therapy, Combination; Etretinate; Humans; Mucous Membrane; PUVA Therapy; Skin; Skin Diseases

1993
[Trans-acitretin is metabolized back to etretinate. Importance for oral retinoid therapy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1996, Volume: 47, Issue:3

    Topics: Acitretin; Administration, Oral; Animals; Biotransformation; Drug Monitoring; Esterification; Etretinate; Female; Half-Life; Humans; Keratolytic Agents; Pregnancy; Psoriasis; Treatment Outcome

1996
Oral retinoids and pregnancy.
    The Medical journal of Australia, 1996, Aug-05, Volume: 165, Issue:3

    Topics: Abnormalities, Drug-Induced; Acitretin; Administration, Oral; Etretinate; Female; Humans; Isotretinoin; Keratolytic Agents; Pregnancy

1996
Prolonged treatment with oral retinoids in adults: no influence on the frequency and severity of spinal abnormalities.
    The British journal of dermatology, 1996, Volume: 134, Issue:1

    Topics: Acitretin; Adult; Age Factors; Drug Administration Schedule; Etretinate; Female; Follow-Up Studies; Humans; Hyperostosis, Diffuse Idiopathic Skeletal; Keratolytic Agents; Male; Middle Aged; Osteoporosis; Prospective Studies; Radiography; Spinal Diseases

1996
Vitamin A and its congeners.
    Seminars in perinatology, 1997, Volume: 21, Issue:2

    Topics: Abnormalities, Drug-Induced; Acitretin; Etretinate; Female; Humans; Isotretinoin; Pregnancy; Retinoids; Tretinoin; Vitamin A

1997
Combined topical calcipotriene ointment 0.005% and various systemic therapies in the treatment of plaque-type psoriasis vulgaris: review of the literature and results of a survey sent to 100 dermatologists.
    Journal of the American Academy of Dermatology, 1997, Volume: 37, Issue:3 Pt 2

    Topics: Acitretin; Administration, Topical; Calcitriol; Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Drug Synergism; Drug Therapy, Combination; Etretinate; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Ointments; Phototherapy; Psoriasis; Risk; Safety; Treatment Outcome

1997
Pharmacokinetics of acitretin and etretinate.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:2 Pt 3

    Topics: Acitretin; Drug Interactions; Etretinate; Humans; Intestinal Absorption; Keratolytic Agents

1998
Acitretin in psoriasis: an overview of adverse effects.
    Journal of the American Academy of Dermatology, 1999, Volume: 41, Issue:3 Pt 2

    Topics: Abnormalities, Drug-Induced; Acitretin; Drug Interactions; Etretinate; Eye Diseases; Female; Humans; Hyperlipidemias; Hyperostosis; Keratolytic Agents; Liver; Male; Mucous Membrane; Pancreatitis; Pseudotumor Cerebri; Skin Diseases

1999
Treatment of psoriasis with retinoids: present status.
    Cutis, 1999, Volume: 64, Issue:5

    Topics: Acitretin; Etretinate; Humans; Keratolytic Agents; Psoriasis; Retinoids

1999
Transition from methotrexate and cyclosporine to other therapies including retinoids, ultraviolet light and biologic agents in the management of patients with psoriasis.
    The Journal of dermatological treatment, 2003, Volume: 14 Suppl 2

    Topics: Acitretin; Cyclosporine; Drug Therapy, Combination; Etretinate; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Phototherapy; Psoriasis; Recombinant Fusion Proteins; Treatment Outcome

2003
Systemic and topical retinoids in the management of skin cancer in organ transplant recipients.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004, Volume: 30, Issue:4 Pt 2

    Topics: Acitretin; Administration, Oral; Administration, Topical; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Chemoprevention; Etretinate; Humans; Organ Transplantation; Precancerous Conditions; Retinoids; Skin Neoplasms

2004
Vitamin A: a multifunctional tool for development.
    Seminars in cell & developmental biology, 2011, Volume: 22, Issue:6

    Topics: Acitretin; Aldehyde Oxidoreductases; Animals; Cell Differentiation; Cell Proliferation; Chickens; Developmental Biology; Embryo, Mammalian; Etretinate; Female; Fetal Development; Fetus; Gene Expression Regulation, Developmental; Humans; Mice; Pregnancy; Signal Transduction; Vitamin A; Vitamin A Deficiency

2011
The effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:8

    Topics: Acitretin; Administration, Topical; Alcohol Drinking; Chronic Disease; Ethanol; Etretinate; Folic Acid Antagonists; Humans; Keratolytic Agents; Psoriasis; Skin

2012

Trials

17 trial(s) available for acitretin and etretinate

ArticleYear
A double-blind comparison of acitretin and etretinate in the treatment of Darier's disease.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:2

    Topics: Acitretin; Adolescent; Adult; Aged; Darier Disease; Double-Blind Method; Etretinate; Female; Humans; Male; Middle Aged; Tretinoin

1992
A double-blind comparison of acitretin and etretinate in combination with bath PUVA in the treatment of extensive psoriasis.
    The British journal of dermatology, 1989, Volume: 121, Issue:1

    Topics: Acitretin; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Etretinate; Female; Humans; Male; Psoriasis; PUVA Therapy; Random Allocation; Tretinoin

1989
Acitretin in the treatment of severe psoriasis: a randomized double-blind study comparing acitretin and etretinate.
    Acta dermato-venereologica. Supplementum, 1989, Volume: 146

    Topics: Acitretin; Adult; Double-Blind Method; Etretinate; Humans; Male; Middle Aged; Psoriasis; Random Allocation; Tretinoin

1989
Acitretin versus etretinate in severe psoriasis. A double-blind randomized Nordic multicenter study in 168 patients.
    Acta dermato-venereologica. Supplementum, 1989, Volume: 146

    Topics: Acitretin; Double-Blind Method; Etretinate; Female; Humans; Male; Multicenter Studies as Topic; Psoriasis; Random Allocation; Tretinoin

1989
A double-blind comparison of acitretin and etretinate in the treatment of severe psoriasis. Results of a Nordic multicentre study.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:1

    Topics: Acitretin; Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Etretinate; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psoriasis; Random Allocation; Tretinoin

1989
Etretin therapy for severe psoriasis. Evaluation of initial clinical responses.
    Archives of dermatology, 1987, Volume: 123, Issue:1

    Topics: Acitretin; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Etretinate; Female; Follow-Up Studies; Humans; Male; Middle Aged; Psoriasis; Random Allocation; Time Factors; Tretinoin

1987
Single dose pharmacokinetics of etretin and etretinate in psoriatic patients.
    Pharmacology & toxicology, 1987, Volume: 61, Issue:2

    Topics: Acitretin; Adult; Aged; Drug Administration Schedule; Etretinate; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Psoriasis; Random Allocation; Tretinoin

1987
Acitretin versus etretinate in psoriasis. Clinical and pharmacokinetic results of a German multicenter study.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:3

    Topics: Acitretin; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Etretinate; Female; Humans; Male; Middle Aged; Psoriasis; Random Allocation; Tretinoin

1988
Acitretin and etretinate in the treatment of palmoplantar pustulosis: a double-blind comparative trial.
    The British journal of dermatology, 1988, Volume: 119, Issue:6

    Topics: Acitretin; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Etretinate; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Aged; Random Allocation; Tretinoin

1988
Randomized double-blind multicenter study comparing acitretin-PUVA, etretinate-PUVA and placebo-PUVA in the treatment of severe psoriasis.
    Dermatologica, 1988, Volume: 177, Issue:4

    Topics: Acitretin; Adult; Clinical Trials as Topic; Double-Blind Method; Etretinate; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psoriasis; PUVA Therapy; Random Allocation; Remission Induction; Tretinoin

1988
Acitretin (Ro 10-1670) in the treatment of severe psoriasis. A randomized double-blind parallel study comparing acitretin and etretinate.
    International journal of dermatology, 1988, Volume: 27, Issue:9

    Topics: Acitretin; Adult; Aged; Double-Blind Method; Etretinate; Female; Humans; Male; Middle Aged; Psoriasis; Time Factors; Tretinoin

1988
[Etretinate: pro and con. Risk-benefit analysis of systemic retinoid therapy in psoriasis and recent developments: free aromatic acid, arotinoids].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1985, Volume: 36, Issue:1

    Topics: Abnormalities, Drug-Induced; Acitretin; Benzoates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Etretinate; Humans; Lipids; Long-Term Care; Prognosis; Psoriasis; Retinoids; Risk; Skin; Tretinoin

1985
Etretinate: effect of milk intake on absorption.
    The Journal of investigative dermatology, 1984, Volume: 82, Issue:6

    Topics: Acitretin; Animals; Darier Disease; Etretinate; Humans; Milk; Psoriasis; Tretinoin; Water

1984
Inability to detect plasma etretinate and acitretin is a poor predictor of the absence of these teratogens in tissue after stopping acitretin treatment.
    British journal of clinical pharmacology, 1994, Volume: 38, Issue:3

    Topics: Acitretin; Adipose Tissue; Adolescent; Adult; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Etretinate; Female; Follow-Up Studies; Humans; Middle Aged; Netherlands; Product Surveillance, Postmarketing; Sensitivity and Specificity; Single-Blind Method; Skin Diseases; Teratogens; Tissue Distribution

1994
An appraisal of acitretin therapy in children with inherited disorders of keratinization.
    The British journal of dermatology, 1996, Volume: 134, Issue:6

    Topics: Acitretin; Child; Child, Preschool; Drug Administration Schedule; Etretinate; Female; Follow-Up Studies; Humans; Hyperkeratosis, Epidermolytic; Ichthyosis; Ichthyosis, Lamellar; Infant; Keratolytic Agents; Male; Sjogren-Larsson Syndrome

1996
Assessment of acitretin-treated female patients of childbearing age and subsequent risk of teratogenicity.
    The British journal of dermatology, 2001, Volume: 145, Issue:6

    Topics: Acitretin; Adult; Biotransformation; Ethanol; Etretinate; Female; Humans; Keratolytic Agents; Psoriasis

2001
A fully validated HPLC method for the simultaneous determination of acitretin and etretinate in plasma and its application to a pharmacokinetic study in healthy Korean subjects.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:7

    Topics: Acitretin; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Etretinate; Half-Life; Humans; Keratolytic Agents; Male; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2009

Other Studies

80 other study(ies) available for acitretin and etretinate

ArticleYear
Fluorinated retinoic acids and their analogues. 1. Synthesis and Biological activity of (4-methoxy-2,3,6-trimethylphenyl)nonatetraenoic acid analogues.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:9

    Topics: Animals; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tretinoin

1979
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antitumor action of retinoids: inhibition of tumor cell line-induced angiogenesis and prevention of tumors in mice.
    Dermatology (Basel, Switzerland), 1992, Volume: 184, Issue:2

    Topics: Acitretin; Animals; Etretinate; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Sarcoma, Experimental; Tretinoin; Tumor Cells, Cultured

1992
Therapeutic drug monitoring of retinoids.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:3

    Topics: Acitretin; Chromatography, High Pressure Liquid; Drug Monitoring; Etretinate; Female; Humans; Retinoids

1992
A potentially new metabolic pathway: ethyl esterification of acitretin.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:8

    Topics: Acitretin; Animals; Chromatography, High Pressure Liquid; Esterification; Etretinate; Humans; In Vitro Techniques; Liver; Male; Mass Spectrometry; Rats

1992
Comparative binding of etretinate and acitretin to plasma proteins and erythrocytes.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Acitretin; Adult; Blood Proteins; Dialysis; Erythrocyte Membrane; Erythrocytes; Etretinate; Humans; Kinetics; Lipoproteins; Lipoproteins, LDL; Male; Protein Binding

1992
Pharmacokinetics and drug interactions of etretinate and acitretin.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:6 Pt 2

    Topics: Acitretin; Adult; Aged; Chromatography, High Pressure Liquid; Drug Interactions; Etretinate; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged

1992
Psoriasis symposum. Retinoids.
    Seminars in dermatology, 1992, Volume: 11, Issue:4 Suppl 1

    Topics: Acitretin; Etretinate; Humans; Psoriasis; Retinoids

1992
Retinoid augmentation of bioactive interleukin-1 production by murine keratinocytes.
    The British journal of dermatology, 1992, Volume: 126, Issue:5

    Topics: Acitretin; Animals; Cells, Cultured; DNA; Etretinate; Female; Interleukin-1; Isotretinoin; Keratinocytes; Methoxsalen; Mice; Mice, Inbred BALB C; Retinoids; Tretinoin; Triamcinolone Acetonide; Ultraviolet Rays

1992
Acitretin decreases tumor cell-induced angiogenesis.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1991, Volume: 4, Issue:3

    Topics: Acitretin; Animals; Cell Line; Etretinate; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Tretinoin; Tumor Cells, Cultured

1991
[Acitretin; an example of ad-hoc tracing of users in acute problems with drugs].
    Nederlands tijdschrift voor geneeskunde, 1991, May-25, Volume: 135, Issue:21

    Topics: Acitretin; Aged; Carcinogens; Etretinate; Female; Humans; Legislation, Drug; Male; Middle Aged; Netherlands; Pharmacies; Tretinoin

1991
Cultivation of human dermal microvascular endothelial cells in vitro: immunocytochemical and ultrastructural characterization and effect of treatment with three synthetic retinoids.
    Archives of dermatological research, 1991, Volume: 283, Issue:3

    Topics: Acitretin; beta 2-Microglobulin; Cell Division; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Endothelium, Vascular; Etretinate; Humans; Immunohistochemistry; Infant; Infant, Newborn; Isotretinoin; Lectins; Male; Microscopy, Electron; Retinoids; Time Factors; Tretinoin; Vimentin; von Willebrand Factor

1991
A newly discovered xenobiotic metabolic pathway: ethyl ester formation.
    Life sciences, 1991, Volume: 49, Issue:21

    Topics: Acitretin; Animals; Esterification; Ethanol; Etretinate; Humans; Liver; Rats; Tretinoin

1991
Ichthyosis bullosa of Siemens responds well to low-dosage oral retinoids.
    The British journal of dermatology, 1991, Volume: 125, Issue:5

    Topics: Acitretin; Adult; Drug Administration Schedule; Etretinate; Female; Hand; Humans; Ichthyosiform Erythroderma, Congenital; Leg; Male; Middle Aged; Retinoids; Skin; Tretinoin

1991
Ichthyosis bullosa of Siemens: further delineation of the phenotype.
    Archives of dermatological research, 1990, Volume: 282, Issue:1

    Topics: Acitretin; Adult; Epidermis; Etretinate; Female; Humans; Ichthyosis; Male; Microscopy, Electron; Middle Aged; Pedigree; Phenotype; Tretinoin

1990
[Pharmacokinetics of etretinate, acitretin and 13-cis-acitretin: new results and advantages of blood level oriented clinical use].
    Zeitschrift fur Hautkrankheiten, 1990, Volume: 65, Issue:1

    Topics: Acitretin; Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Etretinate; Female; Humans; Long-Term Care; Male; Middle Aged; Psoriasis; Skin Diseases; Tretinoin

1990
High-performance liquid chromatographic determination of etretinate and all-trans- and 13-cis-acitretin in human plasma.
    Journal of chromatography, 1990, Feb-02, Volume: 500

    Topics: Acitretin; Chromatography, High Pressure Liquid; Etretinate; Humans; Stereoisomerism; Tretinoin

1990
Pharmacokinetic profile of two aromatic retinoids (etretinate and acitretin) in the obese Zucker rat.
    Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:4

    Topics: Acitretin; Animals; Chromatography, High Pressure Liquid; Etretinate; Female; Rats; Rats, Zucker; Tretinoin

1990
Etretin. A replacement for etretinate.
    International journal of dermatology, 1990, Volume: 29, Issue:4

    Topics: Acitretin; Etretinate; Humans; Psoriasis; Tretinoin

1990
Teratogenicity of etretinate during early pregnancy in the rat and its correlation with maternal plasma concentrations of the drug.
    Teratology, 1990, Volume: 42, Issue:1

    Topics: Acitretin; Animals; Dose-Response Relationship, Drug; Etretinate; Female; Fetus; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Teratogens; Tretinoin

1990
In vitro inhibition of prostaglandin biosynthesis in squamous cell carcinoma by retinoids.
    Eicosanoids, 1990, Volume: 3, Issue:2

    Topics: Acitretin; Arachidonic Acid; Arachidonic Acids; Benzoates; Carcinoma, Squamous Cell; Dinoprostone; Dose-Response Relationship, Drug; Etretinate; Humans; Prostaglandin-Endoperoxide Synthases; Retinoids; Tongue Neoplasms; Tretinoin; Tumor Cells, Cultured

1990
Persistent etretinate levels in plasma after changing the therapy to acitretin.
    Archives of dermatological research, 1990, Volume: 282, Issue:5

    Topics: Acitretin; Aged; Drug Interactions; Etretinate; Female; Humans; Male; Middle Aged; Skin Diseases; Tretinoin

1990
Uptake of the aromatic retinoids Ro 10-9359 (etretinate) and Ro 10-1670 (acitretin), its main metabolite, delivered to cultured human fibroblasts by serum proteins. Lack of evidence for perturbation of LDL catabolism.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2

    Topics: Acitretin; Binding, Competitive; Biological Transport; Cells, Cultured; Etretinate; Fibroblasts; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Protein Binding; Serum Albumin; Tretinoin

1990
In vitro interactions of the aromatic retinoids Ro 10-9359 (etretinate) and Ro 10-1670 (acitretin), its main metabolite, with human serum lipoproteins and albumin.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2

    Topics: Acitretin; Etretinate; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Molecular Structure; Protein Binding; Serum Albumin; Tretinoin

1990
Teratogenicity of steady-state concentrations of etretinate and metabolite acitretin maintained in maternal plasma and embryo by intragastric infusion during organogenesis in the mouse: a possible model for the extended elimination phase in human therapy.
    Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:1

    Topics: Abnormalities, Drug-Induced; Acitretin; Animals; Embryonic and Fetal Development; Etretinate; Female; Infusion Pumps, Implantable; Maternal-Fetal Exchange; Mice; Models, Biological; Pregnancy; Tretinoin

1990
UV-induced isomerization of oral retinoids in vitro and in vivo in hairless mice.
    Photodermatology, photoimmunology & photomedicine, 1990, Volume: 7, Issue:4

    Topics: Acitretin; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Etretinate; Female; In Vitro Techniques; Isomerism; Isotretinoin; Mice; Mice, Hairless; Retinoids; Skin; Tretinoin; Ultraviolet Rays

1990
Effects of retinoids on DNA synthesis of pig epidermis: its relation to epidermal beta-adrenergic adenylate cyclase response and to epidermal superoxide dismutase activity.
    Journal of dermatological science, 1990, Volume: 1, Issue:4

    Topics: Acitretin; Adenylyl Cyclases; Animals; Cell Division; DNA; Epidermis; Etretinate; Keratinocytes; Retinoids; Superoxide Dismutase; Swine; Thymidine; Tretinoin; Vitamin A

1990
Tissue distribution of aromatic retinoid (etretinate) in three autopsy cases: drug accumulation in adrenals and fat.
    Acta dermato-venereologica, 1986, Volume: 66, Issue:5

    Topics: Acitretin; Adipose Tissue; Adrenal Glands; Adult; Aged; Aged, 80 and over; Etretinate; Humans; Ichthyosis; Male; Psoriasis; Tissue Distribution; Tretinoin

1986
Neutrophil function in psoriasis: effects of retinoids.
    Acta dermato-venereologica, 1987, Volume: 67, Issue:6

    Topics: Acitretin; Dermatologic Agents; Etretinate; Female; Humans; In Vitro Techniques; Isotretinoin; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Psoriasis; Retinoids; Tetradecanoylphorbol Acetate; Tretinoin

1987
Comparison of the effects of retinoids and glucocorticosteroid on protein and type IV collagen synthesis in HT-1080 (human basement membrane forming fibrosarcoma) cells.
    Dermatologica, 1989, Volume: 179, Issue:1

    Topics: Acitretin; Collagen; Dexamethasone; Electrophoresis, Starch Gel; Etretinate; Fibronectins; Fibrosarcoma; Isotretinoin; Retinoids; Tretinoin; Tumor Cells, Cultured; Vitamin A

1989
Pharmacokinetics of etretinate in psoriatic patients with liver fibrosis.
    Pharmacology & toxicology, 1989, Volume: 65, Issue:5

    Topics: Acitretin; Aged; Etretinate; Female; Half-Life; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Psoriasis; Tretinoin

1989
Inefficacy of the synthetic aromatic retinoid etretinate and of its free acid on the in-vitro differentiation of leukemic cells.
    Leukemia research, 1986, Volume: 10, Issue:9

    Topics: Acitretin; Cell Differentiation; Cell Line; Etretinate; Humans; Leukemia, Myeloid, Acute; Stereoisomerism; Structure-Activity Relationship; Tretinoin

1986
Simultaneous determination of the aromatic retinoids etretin and etretinate and their main metabolites by reversed-phase liquid chromatography.
    Journal of chromatography, 1987, Apr-10, Volume: 415, Issue:2

    Topics: Acitretin; Chromatography, High Pressure Liquid; Etretinate; Humans; Isomerism; Kinetics; Psoriasis; Tretinoin

1987
Etretinate pharmacokinetics in chronic renal failure. A preliminary study in psoriasis patients.
    Dermatologica, 1987, Volume: 175, Issue:5

    Topics: Acitretin; Etretinate; Humans; Kidney Failure, Chronic; Kidney Function Tests; Psoriasis; Tretinoin

1987
Pharmacokinetics of etretin and etretinate during long-term treatment of psoriasis patients.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:3

    Topics: Acitretin; Adult; Aged; Etretinate; Female; Half-Life; Humans; Male; Middle Aged; Psoriasis; Tretinoin

1988
Acitretin (Ro 10-1670, etretin): overall evaluation of clinical studies.
    Dermatologica, 1988, Volume: 176, Issue:4

    Topics: Acitretin; Adolescent; Adult; Child; Child, Preschool; Etretinate; Female; Humans; Male; Middle Aged; Psoriasis; Skin; Tretinoin

1988
Fish oil supplementation results in decreased hypertriglyceridemia in patients with psoriasis undergoing etretinate or acitretin therapy.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:1 Pt 1

    Topics: Acitretin; Adult; Aged; Cholesterol; Cholesterol, HDL; Etretinate; Female; Fish Oils; Humans; Hyperlipoproteinemias; Male; Middle Aged; Prothrombin Time; Psoriasis; Tretinoin; Triglycerides

1988
["Crocodile baby", a non-fatal form of malignant keratoma?].
    Annales de dermatologie et de venereologie, 1988, Volume: 115, Issue:3

    Topics: Acitretin; Adult; Dermatitis, Exfoliative; Diagnosis, Differential; Etretinate; Female; Humans; Ichthyosis; Keratosis; Optic Atrophy; Pedigree; Tretinoin

1988
Simultaneous microassay for etretinate and its active metabolite, etretin, by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1988, Dec-09, Volume: 433

    Topics: Acitretin; Animals; Chromatography, High Pressure Liquid; Diterpenes; Etretinate; Rats; Retinyl Esters; Spectrophotometry, Ultraviolet; Tretinoin; Vitamin A

1988
Quantitative analysis of retinoids in biological fluids by high-performance liquid chromatography using column switching. II. Simultaneous determination of etretinate, acitretin and 13-cis-acitretin in plasma.
    Journal of chromatography, 1988, Oct-14, Volume: 431, Issue:2

    Topics: Acitretin; Animals; Chromatography, High Pressure Liquid; Etretinate; Humans; Indicators and Reagents; Mice; Rats; Retinoids; Solutions; Temperature; Tretinoin

1988
Transplacental pharmacokinetics of teratogenic doses of etretinate and other aromatic retinoids in mice.
    Reproductive toxicology (Elmsford, N.Y.), 1988, Volume: 2, Issue:1

    Topics: Abnormalities, Drug-Induced; Acitretin; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Etretinate; Female; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Molecular Structure; Placenta; Pregnancy; Tretinoin

1988
Metabolism of an aromatic retinoid Ro 10-9359 by cultured human epidermal keratinocytes.
    Archives of dermatological research, 1982, Volume: 273, Issue:3-4

    Topics: Acitretin; Animals; Cells, Cultured; Child; Epidermis; Etretinate; Female; Fibroblasts; HeLa Cells; Humans; Keratins; Liver; Mice; Tretinoin

1982
High-performance liquid chromatography of Ro 10-9359 (tigason) and its metabolite Ro 10-1670 in human plasma.
    Journal of chromatography, 1982, Sep-10, Volume: 231, Issue:2

    Topics: Acitretin; Chromatography, High Pressure Liquid; Diterpenes; Etretinate; Humans; Retinyl Esters; Tretinoin; Vitamin A

1982
Inhibition of neutrophil migration by etretinate and its main metabolite.
    The British journal of dermatology, 1982, Volume: 107, Issue:6

    Topics: Acitretin; Adult; Blood Bactericidal Activity; Cell Movement; Dose-Response Relationship, Drug; Etretinate; Humans; Male; Neutrophils; Phagocytosis; Skin; Tretinoin

1982
Plasma and suction blister fluid levels of etretinate and its main metabolite during treatment of psoriasis.
    Archives of dermatological research, 1982, Volume: 272, Issue:1-2

    Topics: Acitretin; Adult; Biological Availability; Blister; Etretinate; Exudates and Transudates; Female; Half-Life; Humans; Male; Middle Aged; Psoriasis; Time Factors; Tretinoin

1982
[Antitumor effects of aromatic retinoids (Ro 10-1670, Ro 10-9359) on the chemically-induced epithelial tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acitretin; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cricetinae; Etretinate; Mesocricetus; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tretinoin

1982
Retinoid concentrations in skin, serum and adipose tissue of patients treated with etretinate.
    The British journal of dermatology, 1983, Volume: 109, Issue:4

    Topics: Acitretin; Adipose Tissue; Adolescent; Adult; Aged; Biological Availability; Child; Etretinate; Female; Humans; Male; Middle Aged; Skin; Skin Diseases; Tretinoin

1983
Serum levels of Etretinate (Ro 10-9359) and its metabolite (Ro 10-1670).
    The Journal of dermatology, 1983, Volume: 10, Issue:5

    Topics: Acitretin; Adolescent; Adult; Etretinate; Female; Humans; Keratoderma, Palmoplantar; Male; Middle Aged; Pityriasis; Psoriasis; Tretinoin

1983
Analysis of retinoids by high-performance liquid chromatography using programmed gradient separation.
    Journal of chromatography, 1984, Jan-13, Volume: 305, Issue:1

    Topics: Acitretin; Chromatography, High Pressure Liquid; Diterpenes; Etretinate; Humans; Retinoids; Retinyl Esters; Tretinoin; Vitamin A

1984
Effect of vitamin A and its derivatives on collagen production and chemotactic response of fibroblasts.
    The British journal of dermatology, 1984, Volume: 111, Issue:1

    Topics: Acitretin; Cell Division; Cells, Cultured; Chemotaxis; Collagen; Etretinate; Fibroblasts; Humans; Isotretinoin; Protein Biosynthesis; Tretinoin; Vitamin A

1984
[Inhibitory effects of aromatic retinoic acid analog, administered alone or in combination with mitomycin C, on the in vitro growth of rat bladder carcinoma cells].
    Hinyokika kiyo. Acta urologica Japonica, 1984, Volume: 30, Issue:11

    Topics: Acitretin; Animals; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Etretinate; Mitomycin; Mitomycins; Rats; Tretinoin; Urinary Bladder Neoplasms

1984
Determination of plasma levels of two aromatic retinoic acid analogues with antipsoriatic activity by high-performance liquid chromatography.
    Journal of chromatography, 1980, Dec-12, Volume: 221, Issue:2

    Topics: Acitretin; Chromatography, High Pressure Liquid; Etretinate; Humans; Kinetics; Reference Standards; Spectrophotometry, Ultraviolet; Tretinoin

1980
Retinoid stimulates epidermal outgrowth of pig skin explants.
    The Journal of dermatology, 1981, Volume: 8, Issue:3

    Topics: Acitretin; Animals; Culture Techniques; Epidermal Cells; Epidermis; Etretinate; Mitosis; Swine; Tretinoin

1981
Simultaneous determination of etretinate, acitretin and their metabolites in perfusate, perfusate plasma, bile or hepatic tissue with reversed-phase high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1995, May-05, Volume: 667, Issue:1

    Topics: Acitretin; Animals; Bile; Chromatography, High Pressure Liquid; Etretinate; Liver; Rats; Reproducibility of Results; Spectrophotometry, Ultraviolet

1995
Extensive extraspinal hyperostoses after long-term oral retinoid treatment in a patient with pityriasis rubra pilaris.
    Journal of the American Academy of Dermatology, 1995, Volume: 32, Issue:2 Pt 2

    Topics: Acetabulum; Acitretin; Adolescent; Adult; Azathioprine; Child; Etretinate; Exostoses; Femur Neck; Follow-Up Studies; Humans; Hyperostosis; Male; Methotrexate; Pityriasis Rubra Pilaris; Retinoids; Tretinoin

1995
Skin, adipose tissue and plasma levels of acitretin with rare occurrence of esterified acitretin during long-term treatment.
    Acta dermato-venereologica, 1993, Volume: 73, Issue:2

    Topics: Acitretin; Adipose Tissue; Adult; Aged; Chromatography, High Pressure Liquid; Esterification; Etretinate; Female; Humans; Keratosis; Male; Middle Aged; Psoriasis; Skin; Time Factors

1993
Acitretin biotransformation into etretinate: role of ethanol on in vitro hepatic metabolism.
    Dermatology (Basel, Switzerland), 1994, Volume: 188, Issue:2

    Topics: Acitretin; Animals; Biotransformation; Cells, Cultured; Dogs; Esterification; Ethanol; Etretinate; Humans; Liver; Macaca fascicularis; Male; Rats; Rats, Wistar

1994
The effects of retinoids and terbinafine on the human hepatic microsomal metabolism of cyclosporin.
    The British journal of dermatology, 1993, Volume: 129, Issue:4

    Topics: Acitretin; Aged; Antifungal Agents; Cyclosporine; Drug Therapy, Combination; Etretinate; Female; Humans; In Vitro Techniques; Isotretinoin; Male; Microsomes, Liver; Middle Aged; Naphthalenes; Psoriasis; Retinoids; Terbinafine

1993
In vivo skin penetration of acitretin in volunteers using three sampling techniques.
    Pharmaceutical research, 1993, Volume: 10, Issue:9

    Topics: Acitretin; Administration, Topical; Adult; Blood Specimen Collection; Etretinate; Humans; Male; Skin Absorption

1993
[Cyclosporine and Darier's disease].
    Annales de dermatologie et de venereologie, 1993, Volume: 120, Issue:4

    Topics: Acitretin; Cyclosporine; Darier Disease; Etretinate; Humans; Male; Middle Aged; Treatment Failure

1993
Psoriasis and birdshot chorioretinopathy: response to aromatic retinoids.
    Dermatology (Basel, Switzerland), 1993, Volume: 187, Issue:2

    Topics: Acitretin; Chorioretinitis; Drug Therapy, Combination; Etretinate; Humans; Male; Middle Aged; Psoriasis; Vitiligo

1993
Conversion of acitretin to etretinate in psoriatic patients is influenced by ethanol.
    The Journal of investigative dermatology, 1993, Volume: 100, Issue:5

    Topics: Acitretin; Adult; Alcohol Drinking; Ethanol; Etretinate; Female; Half-Life; Humans; Male; Middle Aged; Osmolar Concentration; Psoriasis; Time Factors

1993
Keratoderma with scleroatrophy of the extremities or sclerotylosis (Huriez syndrome): a reappraisal.
    The British journal of dermatology, 1995, Volume: 133, Issue:3

    Topics: Acitretin; Adult; Carcinoma, Squamous Cell; DNA Repair; Drug Therapy, Combination; Etretinate; Female; Genetic Linkage; Humans; Keratoderma, Palmoplantar; Keratolytic Agents; Male; Middle Aged; Pedigree; Skin Neoplasms

1995
Mechanistic studies on the ethyl-esterification of acitretin by human liver preparations in vitro.
    Life sciences, 1995, Nov-17, Volume: 57, Issue:26

    Topics: Acitretin; Adenosine Triphosphate; Coenzyme A; Esterification; Ethanol; Etretinate; Humans; Keratolytic Agents; Liver; Microsomes, Liver; NADP

1995
Concentration of etretinate in plasma and subcutaneous fat after long-term acitretin.
    Lancet (London, England), 1996, Oct-19, Volume: 348, Issue:9034

    Topics: Acitretin; Adipose Tissue; Adult; Etretinate; Female; Humans; Keratolytic Agents

1996
Etretinate may work where acitretin fails.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Topics: Acitretin; Adolescent; Adult; Aged; Aged, 80 and over; Darier Disease; Etretinate; Female; Hand Dermatoses; Humans; Keratoderma, Palmoplantar; Keratolytic Agents; Male; Psoriasis; Skin Diseases; Treatment Failure

1997
Skeletal changes after long-term therapy with synthetic retinoids.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Topics: Acitretin; Adult; Aged; Bone and Bones; Etretinate; Female; Humans; Keratolytic Agents; Male; Time Factors

1997
In vitro effects of retinoids on mitogen-induced peripheral blood leucocyte responses.
    Archives of dermatological research, 1998, Volume: 290, Issue:4

    Topics: Acitretin; Adult; Carcinogens; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Etretinate; Humans; Immunosuppressive Agents; Isotretinoin; Keratolytic Agents; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lymphocyte Activation; Lymphocytes; Middle Aged; Mitogens; Phytohemagglutinins; Polyenes; Retinoids; Sirolimus; Tetradecanoylphorbol Acetate

1998
In vitro metabolism of acitretin by human liver microsomes: evidence of an acitretinoyl-coenzyme A thioester conjugate in the transesterification to etretinate.
    Biochemical pharmacology, 2000, Aug-15, Volume: 60, Issue:4

    Topics: Acetaldehyde; Acetates; Acitretin; Acyl Coenzyme A; Coenzyme A Ligases; Esterification; Ethanol; Etretinate; Humans; In Vitro Techniques; Microsomes, Liver; Repressor Proteins; Saccharomyces cerevisiae Proteins

2000
Acitretin is converted to etretinate only during concomitant alcohol intake.
    The British journal of dermatology, 2000, Volume: 143, Issue:6

    Topics: Acitretin; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Ethanol; Etretinate; Female; Humans; Keratolytic Agents; Logistic Models; Male; Middle Aged; Risk Factors; Skin Diseases

2000
[Treatment with acitretin and alcohol drinking: a high risk combination].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:11

    Topics: Acitretin; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Biotransformation; Dose-Response Relationship, Drug; Drug Interactions; Etretinate; Female; Humans; Infant, Newborn; Male; Metabolic Clearance Rate; Middle Aged; Pregnancy; Risk Factors

2001
Case studies in severe psoriasis: A clinical strategy.
    The Journal of dermatological treatment, 2003, Volume: 14 Suppl 2

    Topics: Acitretin; Adolescent; Adult; Aged; Algorithms; Dermatologic Agents; Drug Therapy, Combination; Etretinate; Female; Health Surveys; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Recombinant Fusion Proteins; Severity of Illness Index; Treatment Outcome; Ultraviolet Therapy

2003
Evidence for a probable causal relationship between tretinoin, acitretin, and etretinate and intracranial hypertension.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2004, Volume: 24, Issue:3

    Topics: Acitretin; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Child; Etretinate; Female; Humans; Intracranial Hypertension; Keratolytic Agents; Male; Registries; Tretinoin; United States; United States Food and Drug Administration; Vision Disorders; World Health Organization

2004
Oral retinoid therapy for disorders of keratinization: single-centre retrospective 25 years' experience on 23 patients.
    The British journal of dermatology, 2006, Volume: 154, Issue:2

    Topics: Acitretin; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Drug Administration Schedule; Etretinate; Female; Follow-Up Studies; Humans; Hyperostosis; Keratolytic Agents; Keratosis; Middle Aged; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Radiography; Retinoids; Retrospective Studies; Spinal Diseases

2006
Twenty-one years of oral retinoid therapy in siblings with nonbullous ichthyosiform erythroderma.
    Clinical and experimental dermatology, 2008, Volume: 33, Issue:2

    Topics: Acitretin; Adult; Etretinate; Humans; Ichthyosiform Erythroderma, Congenital; Keratolytic Agents; Male; Siblings; Treatment Outcome

2008
Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.
    Cancer chemotherapy and pharmacology, 2008, Volume: 63, Issue:1

    Topics: Acitretin; Alitretinoin; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Culture Media, Conditioned; Etretinate; Fibroblasts; Fluorouracil; Humans; In Vitro Techniques; Isotretinoin; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Retinoids; Tretinoin

2008
Evaluation of the transfusion safety of blood products and determination of plasma concentrations of acitretin and etretinate in patients receiving transfusions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acitretin; Adolescent; Adult; Aged; Biological Products; Blood Donors; Blood Transfusion; Chromatography, High Pressure Liquid; Drug Contamination; Etretinate; Female; Half-Life; Humans; Male; Middle Aged; Psoriasis; Teratogens; Transfusion Reaction

2008
Blood donors on teratogenic drugs and donor deferral periods in a clinical situation.
    Vox sanguinis, 2012, Volume: 102, Issue:4

    Topics: Acitretin; Adult; Blood Donors; Etretinate; Female; Finasteride; Humans; Teratogens; Transfusion Reaction; Young Adult

2012
Acitretin prescribing patterns in women of childbearing potential.
    Journal of drugs in dermatology : JDD, 2013, Jul-01, Volume: 12, Issue:7

    Topics: Acitretin; Adult; Age Factors; Aged; Databases, Factual; Etretinate; Female; Health Care Surveys; Humans; Keratolytic Agents; Male; Middle Aged; Practice Patterns, Physicians'; Psoriasis; Severity of Illness Index; United States

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