Compounds > acifran

Page last updated: 2024-08-23

acifran and niacin

acifran has been researched along with niacin in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (22.22)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (66.67)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cayen, MN; Jirkovsky, I	1
Barnes, AA; Brown, AJ; Dowell, SJ; Eilert, M; Elshourbagy, N; Foord, SM; Fraser, NJ; Green, A; Hassall, DG; Ignar, DM; Marshall, FH; Murdock, PR; Pike, NB; Steplewski, K; Szekeres, PG; Wilson, S; Wise, A	1
Boatman, PD; Chen, R; Connolly, DT; Decaire, M; Duong, T; Gharbaoui, T; Johnson, BR; Jung, JK; Richman, JG; Sage, CR; Semple, G; Uy, J	1
Boatman, PD; Richman, JG; Semple, G	1
Chen, R; Connolly, DT; Dang, TH; Pride, CC; Richman, JG; Sage, CR; Semple, G; Skinner, PJ; Tamura, SY; Webb, PJ	1
IJzerman, AP; Liu, R; Louvel, J; Mooiman, C; Thee, SA; van Veldhoven, JP; Verhoork, SJ; Wouters, Y	1
Cayen, MN; Dubuc, J; Dvornik, D; Greselin, E; Kallai-Sanfacon, MA	1
Pike, NB; Wise, A	1
Adamus, JE; Bergenhem, N; Letsinger, JT; Mahboubi, K; Moorman, AR; Ross, SA; Sawicki, D; Whitehouse, D; Witman-Jones, T	1

Reviews

2 review(s) available for acifran and niacin

Article	Year
Nicotinic acid receptor agonists. Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24 Topics: Animals; Chemistry, Pharmaceutical; Drug Design; Dyslipidemias; Humans; Kinetics; Ligands; Mice; Models, Chemical; Nicotinic Agonists; ortho-Aminobenzoates; Receptors, G-Protein-Coupled; Receptors, Nicotinic	2008
Identification of a nicotinic acid receptor: is this the molecular target for the oldest lipid-lowering drug? Current opinion in investigational drugs (London, England : 2000), 2004, Volume: 5, Issue:3 Topics: Animals; Drug Delivery Systems; Furans; Humans; Hypolipidemic Agents; Ligands; Niacin; Receptors, G-Protein-Coupled; Receptors, Nicotinic	2004

Other Studies

7 other study(ies) available for acifran and niacin

Article	Year
Hypolipidemic 4,5-dihydro-4-oxo-5,5-disubstituted-2-furancarboxylic acids. Journal of medicinal chemistry, 1982, Volume: 25, Issue:10 Topics: Animals; Chemical Phenomena; Chemistry; Clofibrate; Furans; Hypolipidemic Agents; Liver; Male; Niacin; Organ Size; Rats; Rats, Inbred Strains; Triglycerides	1982
Molecular identification of high and low affinity receptors for nicotinic acid. The Journal of biological chemistry, 2003, Mar-14, Volume: 278, Issue:11 Topics: Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Cricetinae; Databases as Topic; DNA, Complementary; Dose-Response Relationship, Drug; Female; Furans; Humans; Hyperlipidemias; Hypolipidemic Agents; Inhibitory Concentration 50; Male; Molecular Sequence Data; Niacin; Oocytes; Protein Binding; Pyrazines; Rats; Receptors, Nicotinic; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Xenopus	2003
Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b. Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7 Topics: Cell Line; Cyclic AMP; Furans; Humans; Niacin; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship	2007
5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b. Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15 Topics: Animals; Atherosclerosis; Carboxylic Acids; Chemistry, Pharmaceutical; CHO Cells; Cricetinae; Cricetulus; Drug Design; Dyslipidemias; Humans; Ligands; Lipoproteins, HDL; Lipoproteins, LDL; Models, Chemical; Niacin; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic	2009
Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists. Bioorganic & medicinal chemistry, 2015, Jul-15, Volume: 23, Issue:14 Topics: Binding, Competitive; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Inhibitory Concentration 50; Kinetics; Niacin; Nicotinic Agonists; ortho-Aminobenzoates; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Structure-Activity Relationship	2015
Effect of AY-25,712 on fatty acid metabolism in rats. Atherosclerosis, 1982, Volume: 45, Issue:3 Topics: Adipose Tissue; Animals; Fatty Acids; Fatty Acids, Nonesterified; Furans; Hypolipidemic Agents; Lipoprotein Lipase; Male; Niacin; Rats; Rats, Inbred Strains; Triglycerides	1982
Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74. Biochemical and biophysical research communications, 2006, Feb-10, Volume: 340, Issue:2 Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Furans; Humans; Hypolipidemic Agents; Lipid Metabolism; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Niacin; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Triglycerides	2006