acid-phosphatase and phenothiazine

acid-phosphatase has been researched along with phenothiazine* in 2 studies

Other Studies

2 other study(ies) available for acid-phosphatase and phenothiazine

Article	Year
Effect of the concentration of phenothiazine photosensitizers in antimicrobial photodynamic therapy on bone loss and the immune inflammatory response of induced periodontitis in rats. Journal of periodontal research, 2014, Volume: 49, Issue:5 Antimicrobial therapy can suppress periodontal pathogens and increase the effectiveness of conventional mechanical treatment. The aim of this study was to assess bone loss and the immune inflammatory response of rats under the influence of two photosensitizing agents (MB and TBO) at two different concentrations in antimicrobial photodynamic therapy (aPDT), used as an adjuvant therapy in the treatment of periodontitis.. Periodontitis was induced in the mandibular first molars of 162 rats. The animals were divided into nine groups: G1 - scaling and root planing (SRP); G2 - SRP plus 100 μg/mL of methylene blue (MB); G3 - SRP plus 10 mg/mL of MB; G4 - SRP plus 100 μg/mL of toluidine blue (TBO); G5 - SRP plus 10 mg/mL of TBO; G6 - SRP plus 100 μg/mL of MB and laser; G7 - SRP plus 10 mg/mL of MB and laser; G8 - SRP plus 100 μg/mL of TBO and laser; and G9 - SRP plus 10 mg/mL of TBO and laser. Six animals from each group were euthanized 7, 15, or 30 d after treatment. Bone loss (BL) in the furcation region was evaluated using histomorphometric and immunohistochemical analyses to detect the receptor activator of nuclear factor-Κappa B ligand (RANKL), osteoprotegerin (OPG) and tartrate-resistant acid phosphatase (TRAP).. There was significantly less BL in animals treated with aPDT using low concentrations of MB and TBO at 7, 15 and 30 d. Immunohistochemical analysis revealed decreased RANKL and increased OPG in the aPDT groups and decreased TRAP-positive cells in G6 and G8.. aPDT, using low concentrations of MB and TBO, was the most effective adjuvant therapy to SRP, acting indirectly as a downregulator of the molecular mechanisms that control bone resorption in periodontitis. Topics: Acid Phosphatase; Alveolar Bone Loss; Animals; Combined Modality Therapy; Connective Tissue; Dental Scaling; Isoenzymes; Low-Level Light Therapy; Lymphocytes; Male; Methylene Blue; Neutrophils; Osteoclasts; Osteoprotegerin; Periodontitis; Phenothiazines; Photochemotherapy; Photosensitizing Agents; RANK Ligand; Rats; Rats, Wistar; Root Planing; Tartrate-Resistant Acid Phosphatase; Time Factors; Tolonium Chloride	2014
[HISTOCHEMICAL REACTIONS IN THE ANIMAL LIVER FOLLOWING SENSITIZATION AND PHENOTHIAZINE OR CORTICOSTEROID ADMINISTRATION]. Allergie und Asthma, 1963, Volume: 9 Topics: Acid Phosphatase; Adrenal Cortex Hormones; Alkaline Phosphatase; Animals; Electron Transport Complex II; Electron Transport Complex IV; Histocytochemistry; Immune Sera; Lipase; Liver; Methylprednisolone; Phenothiazines; Rabbits; Research; Succinate Dehydrogenase	1963

Article

Year

Effect of the concentration of phenothiazine photosensitizers in antimicrobial photodynamic therapy on bone loss and the immune inflammatory response of induced periodontitis in rats.

Journal of periodontal research, 2014, Volume: 49, Issue:5

Antimicrobial therapy can suppress periodontal pathogens and increase the effectiveness of conventional mechanical treatment. The aim of this study was to assess bone loss and the immune inflammatory response of rats under the influence of two photosensitizing agents (MB and TBO) at two different concentrations in antimicrobial photodynamic therapy (aPDT), used as an adjuvant therapy in the treatment of periodontitis.. Periodontitis was induced in the mandibular first molars of 162 rats. The animals were divided into nine groups: G1 - scaling and root planing (SRP); G2 - SRP plus 100 μg/mL of methylene blue (MB); G3 - SRP plus 10 mg/mL of MB; G4 - SRP plus 100 μg/mL of toluidine blue (TBO); G5 - SRP plus 10 mg/mL of TBO; G6 - SRP plus 100 μg/mL of MB and laser; G7 - SRP plus 10 mg/mL of MB and laser; G8 - SRP plus 100 μg/mL of TBO and laser; and G9 - SRP plus 10 mg/mL of TBO and laser. Six animals from each group were euthanized 7, 15, or 30 d after treatment. Bone loss (BL) in the furcation region was evaluated using histomorphometric and immunohistochemical analyses to detect the receptor activator of nuclear factor-Κappa B ligand (RANKL), osteoprotegerin (OPG) and tartrate-resistant acid phosphatase (TRAP).. There was significantly less BL in animals treated with aPDT using low concentrations of MB and TBO at 7, 15 and 30 d. Immunohistochemical analysis revealed decreased RANKL and increased OPG in the aPDT groups and decreased TRAP-positive cells in G6 and G8.. aPDT, using low concentrations of MB and TBO, was the most effective adjuvant therapy to SRP, acting indirectly as a downregulator of the molecular mechanisms that control bone resorption in periodontitis.

Topics: Acid Phosphatase; Alveolar Bone Loss; Animals; Combined Modality Therapy; Connective Tissue; Dental Scaling; Isoenzymes; Low-Level Light Therapy; Lymphocytes; Male; Methylene Blue; Neutrophils; Osteoclasts; Osteoprotegerin; Periodontitis; Phenothiazines; Photochemotherapy; Photosensitizing Agents; RANK Ligand; Rats; Rats, Wistar; Root Planing; Tartrate-Resistant Acid Phosphatase; Time Factors; Tolonium Chloride

2014

[HISTOCHEMICAL REACTIONS IN THE ANIMAL LIVER FOLLOWING SENSITIZATION AND PHENOTHIAZINE OR CORTICOSTEROID ADMINISTRATION].

Allergie und Asthma, 1963, Volume: 9

Topics: Acid Phosphatase; Adrenal Cortex Hormones; Alkaline Phosphatase; Animals; Electron Transport Complex II; Electron Transport Complex IV; Histocytochemistry; Immune Sera; Lipase; Liver; Methylprednisolone; Phenothiazines; Rabbits; Research; Succinate Dehydrogenase

1963