acid-phosphatase and diacetyldichlorofluorescein

acid-phosphatase has been researched along with diacetyldichlorofluorescein* in 1 studies

Other Studies

1 other study(ies) available for acid-phosphatase and diacetyldichlorofluorescein

Article	Year
Induction of apoptosis of monocyte-macrophage lineage cells by 5-S-GAD. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 We found that 5-S-GAD, an insect-derived antibacterial peptide, inhibited murine osteoclast formation in vitro. We examined the specific time point of the inhibitory action of 5-S-GAD on osteoclast formation and found that it mainly suppressed differentiation of osteoclasts in the middle of the culture period. Using HL60 cells that are able to differentiate into multinucleated macrophage-like cells, we found that 5-S-GAD induced apoptosis of HL60 cells by producing H(2)O(2). Thus, the inhibition of osteoclast formation by 5-S-GAD could be, in part, due to apoptosis of the cells of an osteoclast lineage. Topics: Acid Phosphatase; Animals; Anti-Infective Agents; Apoptosis; Bone Marrow; Calcitriol; Cell Lineage; Cells, Cultured; Coculture Techniques; Dihydroxyphenylalanine; Fluoresceins; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Isoenzymes; Macrophages; Mice; Mice, Inbred Strains; Monocytes; Osteoblasts; Tartrate-Resistant Acid Phosphatase	1999

Article

Year

Induction of apoptosis of monocyte-macrophage lineage cells by 5-S-GAD.

FEBS letters, 1999, Sep-03, Volume: 457, Issue:3

We found that 5-S-GAD, an insect-derived antibacterial peptide, inhibited murine osteoclast formation in vitro. We examined the specific time point of the inhibitory action of 5-S-GAD on osteoclast formation and found that it mainly suppressed differentiation of osteoclasts in the middle of the culture period. Using HL60 cells that are able to differentiate into multinucleated macrophage-like cells, we found that 5-S-GAD induced apoptosis of HL60 cells by producing H(2)O(2). Thus, the inhibition of osteoclast formation by 5-S-GAD could be, in part, due to apoptosis of the cells of an osteoclast lineage.

Topics: Acid Phosphatase; Animals; Anti-Infective Agents; Apoptosis; Bone Marrow; Calcitriol; Cell Lineage; Cells, Cultured; Coculture Techniques; Dihydroxyphenylalanine; Fluoresceins; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Isoenzymes; Macrophages; Mice; Mice, Inbred Strains; Monocytes; Osteoblasts; Tartrate-Resistant Acid Phosphatase

1999