acetylleucyl-leucyl-norleucinal and leupeptins

Topics: Coronary Disease; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Testing; Genome-Wide Association Study; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leupeptins; Medication Adherence; Polymorphism, Single Nucleotide; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Risk Factors; Sex Factors; United Kingdom

Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; CHO Cells; Cricetinae; Drug Resistance; Escherichia coli; Kinetics; Leupeptins; Membrane Glycoproteins; Mice; Phenotype; Protease Inhibitors

Topics: Animals; Blotting, Northern; Calcium; Calcium Channels; Calpain; Carrier Proteins; Cattle; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Kainic Acid; Leupeptins; Microfilament Proteins; N-Methylaspartate; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Time Factors

Topics: Animals; beta-Galactosidase; Calcium; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Egtazic Acid; Hydroxymethylglutaryl CoA Reductases; Kinetics; Leupeptins; Oligopeptides; Recombinant Fusion Proteins; Transfection

Topics: Animals; Axons; Blood; Calpain; Endopeptidases; Hirudins; Leupeptins; Neuroblastoma; Osmolar Concentration; Protease Inhibitors; Thrombin; Tumor Cells, Cultured

Topics: Adrenal Gland Neoplasms; Animals; Axons; Chromatography, Affinity; Dose-Response Relationship, Drug; Endopeptidases; Leupeptins; Molecular Weight; Osmolar Concentration; Pheochromocytoma; Protease Inhibitors; Tumor Cells, Cultured

Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Axons; Bucladesine; Cell Adhesion; Chemical Phenomena; Chemistry, Physical; Collagen; Growth; Leupeptins; Molecular Sequence Data; Nerve Fibers; Nerve Growth Factors; Oligopeptides; Pheochromocytoma; Protease Inhibitors; Rats; Time Factors; Tumor Cells, Cultured

Topics: Apolipoprotein B-100; Apolipoproteins B; Biological Transport; Cell Line; Cysteine Proteinase Inhibitors; Hydrolysis; Leupeptins; Liver; Microsomes, Liver

Topics: Base Sequence; Calpain; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cysteine Endopeptidases; E-Selectin; Endothelium, Vascular; Gene Expression; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-8; Leukocytes; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; Oligodeoxyribonucleotides; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; RNA, Messenger; Time Factors; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

Topics: Acetylcysteine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Cricetinae; Cysteine Endopeptidases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endopeptidases; Endoplasmic Reticulum; Humans; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Ubiquitins

Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; I-kappa B Proteins; Leupeptins; Lipopolysaccharides; Mice; Molecular Sequence Data; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Deletion; Serine; Tetradecanoylphorbol Acetate; Transfection

Topics: Amino Acid Sequence; Animals; Calcium; Calpain; Cell Membrane Permeability; Epithelial Cells; Epithelium; In Vitro Techniques; Leupeptins; Molecular Sequence Data; Oligopeptides; Phosphatidylcholines; Protease Inhibitors; Pulmonary Alveoli; Rats

Topics: Animals; Cells, Cultured; CHO Cells; Connexin 43; Cricetinae; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Half-Life; Immunoblotting; Kinetics; Leupeptins; Multienzyme Complexes; Myocardium; Protease Inhibitors; Proteasome Endopeptidase Complex; Rats; Time Factors; Ubiquitins

Topics: Adenosine Triphosphate; Anaphase-Promoting Complex-Cyclosome; Animals; Cell Cycle Proteins; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Electroporation; Enzyme Inhibitors; Humans; Kinetics; Leupeptins; Ligases; Mice; Microtubule-Associated Proteins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rabbits; Recombinant Proteins; Succinates; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitins

Topics: Animals; CHO Cells; Cholesterol Esters; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Esterification; Female; Hydroxycholesterols; Leucine; Leupeptins; Lipoproteins, VLDL; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Sphingomyelin Phosphodiesterase

Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Chaperonin 60; Computer Graphics; Crystallography, X-Ray; Cysteine Endopeptidases; Endopeptidases; Fourier Analysis; Hydrogen Bonding; Leupeptins; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteins; Thermoplasma

Topics: Animals; beta-Galactosidase; Biological Transport; CHO Cells; Cricetinae; Cricetulus; Endopeptidases; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Genes, Reporter; Half-Life; Hydroxymethylglutaryl CoA Reductases; Leupeptins; Membrane Glycoproteins; Protease Inhibitors; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Viral Envelope Proteins

Topics: Animals; Calpain; Cell Adhesion; Cell Size; Cells, Cultured; Glycoproteins; Leupeptins; Mice; Osteoblasts; Parathyroid Hormone

Topics: Alkyl and Aryl Transferases; Base Sequence; Cell Line; Chenodeoxycholic Acid; Codon; DNA-Binding Proteins; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression; Geranyltranstransferase; Hepatoblastoma; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Leupeptins; Liver Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Protease Inhibitors; Receptors, LDL; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transferases; Tumor Cells, Cultured

Topics: Amino Acid Sequence; CCAAT-Enhancer-Binding Proteins; Cholesterol; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Gene Expression Regulation; Humans; Leupeptins; Molecular Sequence Data; Nuclear Proteins; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Sterols; Transcription Factors; Tumor Cells, Cultured

Topics: Amino Acid Sequence; Animals; Antigen Presentation; B-Lymphocytes; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Histocompatibility Antigens Class I; Leupeptins; Lymphocytes; Mice; Molecular Sequence Data; Multienzyme Complexes; Ovalbumin; Protease Inhibitors; Proteasome Endopeptidase Complex; T-Lymphocytes; Ubiquitins

Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Cells, Cultured; Cysteine Endopeptidases; DNA-Binding Proteins; Humans; I-kappa B Proteins; Leupeptins; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Precursors; Protein Processing, Post-Translational; Ubiquitins

Topics: Amino Acid Sequence; Animals; Calpain; Cattle; Cysteine Endopeptidases; Dipeptides; Kinetics; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Pituitary Gland; Protease Inhibitors; Proteasome Endopeptidase Complex; Substrate Specificity

Topics: Apolipoproteins B; Biological Transport; Calpain; Humans; In Vitro Techniques; Leupeptins; Liver; Oleic Acid; Oleic Acids; Protein Processing, Post-Translational; Secretory Rate; Tumor Cells, Cultured

Topics: Animals; Bone Marrow; Bone Marrow Cells; Cathepsin B; Cathepsin D; Cells, Cultured; Intracellular Membranes; Leupeptins; Macrophages; Male; Mice; Protease Inhibitors; Ricin

Topics: Animals; Cell Cycle; CHO Cells; Cricetinae; Cyclins; Cysteine Proteinase Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Kinetics; Leupeptins; Mitosis; Protamine Kinase; Time Factors

Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cytokinins; Drug Resistance; Humans; Leupeptins; Molecular Sequence Data; Oligopeptides; Protease Inhibitors

Topics: Albumins; Ammonium Chloride; Animals; Apolipoproteins E; Brefeldin A; Calcium; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Golgi Apparatus; Humans; Kinetics; Leupeptins; Molecular Sequence Data; Transfection; Tumor Cells, Cultured

Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents; Base Sequence; Cyclins; Cystatins; Cysteine Proteinase Inhibitors; Dexamethasone; Gene Expression; Leupeptins; Mice; Molecular Sequence Data; Rats; Transfection

Topics: 3T3 Cells; Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Calpain; Cell Line; Cell Membrane; Cysteine Proteinase Inhibitors; Hydrolysis; Leupeptins; Mice; Receptors, Cell Surface; Receptors, Erythropoietin

Topics: Base Sequence; Biological Transport; Calpain; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; Endothelium, Vascular; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; Plasminogen Activator Inhibitor 1; Protease Inhibitors; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; RNA, Messenger; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Transfection; Vascular Cell Adhesion Molecule-1

Topics: Ammonium Chloride; Animals; Blotting, Northern; Brefeldin A; Cattle; Cells, Cultured; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum; Leucine; Leupeptins; Ligaments; Microscopy, Electron; Nocodazole; Organelles; Protein Synthesis Inhibitors; RNA, Messenger; Serine Proteinase Inhibitors; Transcription, Genetic; Tropoelastin

Topics: Amino Acid Sequence; Biological Transport; Carrier Proteins; Cell Compartmentation; Cysteine Proteinase Inhibitors; Cytosol; Endoplasmic Reticulum; Histocompatibility Antigens Class I; Leupeptins; Molecular Sequence Data; Oligopeptides; Peptides; Protein Binding

Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dexamethasone; DNA Ligases; Leupeptins; Mice; Mice, Inbred BALB C; Multienzyme Complexes; Proteasome Endopeptidase Complex; Proteins; T-Lymphocytes

Topics: Acetylcysteine; Animals; Apoptosis; Calcium-Binding Proteins; Caspase 1; Cell Survival; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Ligases; Electrophoresis, Polyacrylamide Gel; Leupeptins; Multienzyme Complexes; Nerve Growth Factors; Neurons; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Rats; Sympathetic Nervous System

Topics: Animals; Calcium Chloride; Calpain; Cells, Cultured; Cysteine Proteinase Inhibitors; Hippocampus; Leupeptins; Membrane Potentials; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; Potassium Chloride; Rats; Septum Pellucidum; Spectrin

Topics: beta-Cyclodextrins; Calpain; Carbohydrate Sequence; Circular Dichroism; Cyclodextrins; Cysteine Proteinase Inhibitors; Kinetics; Leupeptins; Molecular Sequence Data

Topics: Amino Acid Sequence; Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Ganglia, Spinal; Humans; Hydrogen-Ion Concentration; Leupeptins; Molecular Sequence Data; Neurofilament Proteins; Neurons; PC12 Cells; Phosphorylation; Precipitin Tests; Protein Kinases; Rats; Stimulation, Chemical

Topics: Biopolymers; Cell Line; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Hydrolysis; Leupeptins; Transcription Factors; Transcription, Genetic; Up-Regulation

Topics: Apoptosis; Calpain; Coumarins; Cycloheximide; Cysteine Proteinase Inhibitors; Diazomethane; HL-60 Cells; Humans; Isocoumarins; Leupeptins; Oligopeptides; Protein Synthesis Inhibitors; Serine Proteinase Inhibitors

Topics: Calpain; Cathepsins; Cell Cycle; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fibroblasts; Humans; Leupeptins; Lung; Multienzyme Complexes; Platelet-Derived Growth Factor; Proteasome Endopeptidase Complex; Tumor Suppressor Protein p53

Topics: Apolipoprotein B-100; Apolipoproteins B; Carrier Proteins; Cell Line; Cholesterol Ester Transfer Proteins; Cysteine Proteinase Inhibitors; Dithiothreitol; Endopeptidases; Glycoproteins; Humans; In Vitro Techniques; Leupeptins; Lipid Metabolism; Lipids; Methaqualone; Microsomes; Triglycerides

Topics: Adenosine Triphosphate; Antibodies; Apolipoproteins B; Blotting, Western; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Leupeptins; Liver; Models, Biological; Multienzyme Complexes; Precipitin Tests; Protease Inhibitors; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Ubiquitins

Topics: Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Biological Transport; Carcinoma, Hepatocellular; Endoplasmic Reticulum; Humans; Immunoblotting; Intracellular Membranes; Leupeptins; Lipoproteins; Liver; Liver Neoplasms; Protease Inhibitors; Trypsin; Tumor Cells, Cultured

Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Ganglia, Spinal; Leupeptins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Nerve Growth Factors; Neurofilament Proteins; Neurons; Oligopeptides; PC12 Cells; Phosphorylation; Protease Inhibitors; Protein Kinases; Rats; Stress, Physiological; Structure-Activity Relationship

Topics: Acetylcysteine; Animals; Antigen-Presenting Cells; Antigens, Viral; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Epitopes; H-2 Antigens; Humans; Leupeptins; Mice; Multienzyme Complexes; Nucleocapsid Proteins; Nucleoproteins; Orthomyxoviridae; Peptides; Proteasome Endopeptidase Complex; Signal Transduction; T-Lymphocytes, Cytotoxic; Vaccinia virus; Viral Core Proteins

Topics: Animals; Cells, Cultured; Feasibility Studies; Female; Gene Expression Regulation; Interleukin-6; Leupeptins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Sepsis; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; beta 2-Microglobulin; Blotting, Western; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Endoplasmic Reticulum; Enzyme Inhibitors; Glycosylation; Histocompatibility Antigens Class I; Humans; Kinetics; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Folding; Solubility; Transfection; Tumor Cells, Cultured

Topics: Acetylcysteine; Animals; Calpain; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dogs; Endoplasmic Reticulum; Fungal Proteins; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Leupeptins; Membrane Glycoproteins; Membrane Proteins; Molecular Chaperones; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Conformation; RNA, Messenger

Topics: Acetylcysteine; Animals; Aryl Hydrocarbon Hydroxylases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Leupeptins; Microsomes, Liver; Mixed Function Oxygenases; Multienzyme Complexes; Oxidoreductases, N-Demethylating; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley

Topics: Cell Nucleus; Cysteine Proteinase Inhibitors; DNA; DNA-Binding Proteins; Humans; I-kappa B Proteins; Leupeptins; Liver; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Protein Precursors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Recombinant Proteins; Transcription Factor RelA; Transcription Factor RelB; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Apolipoproteins B; Biological Transport; Brefeldin A; Cyclopentanes; Cysteine Proteinase Inhibitors; Dithiothreitol; Endoplasmic Reticulum; Humans; Leupeptins; Liver; Models, Biological; Oleic Acid; Peptide Fragments; Protein Synthesis Inhibitors

Topics: Animals; Benzoates; Bone Resorption; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Endopeptidases; Female; Humans; Hypercalcemia; Leupeptins; Male; Osteoporosis; Ovariectomy; Ovary; Parathyroid Glands; Parathyroidectomy; Rats; Rats, Wistar; Retinoids; Thyroid Gland; Thyroidectomy

Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Hydrolysis; Insulin; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Tumor Cells, Cultured

Topics: Acetylcysteine; Animals; Benzoquinones; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Detergents; Enzyme Inhibitors; Half-Life; Humans; Lactams, Macrocyclic; Leupeptins; Mice; Multienzyme Complexes; Mutation; Octoxynol; Polyethylene Glycols; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Quinones; Rats; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins

Topics: Animals; Atrophy; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diaphragm; Kinetics; Leupeptins; Male; Multienzyme Complexes; Muscle, Skeletal; Proteasome Endopeptidase Complex; Proteins; Rats; Rats, Inbred Strains

Topics: Acetylcysteine; Animals; beta-Galactosidase; Blotting, Northern; Carrier Proteins; Cell Cycle Proteins; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Leupeptins; Oligopeptides; Protein Synthesis Inhibitors; Retinoblastoma-Binding Protein 1; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Ubiquitins

Topics: Acetylcysteine; Animals; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cysteine Endopeptidases; Endoplasmic Reticulum; Epitopes; Hexosaminidases; Histocompatibility Antigens Class I; HLA-A2 Antigen; Humans; Leupeptins; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Sorting Signals; Self Tolerance; T-Lymphocytes, Cytotoxic

Topics: Animals; Brain; Cattle; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Leupeptins; Lipopolysaccharides; Multienzyme Complexes; NF-kappa B; NF-kappa B p50 Subunit; Polyenes; Proteasome Endopeptidase Complex; Protein Precursors; Proto-Oncogene Proteins; Sirolimus; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha

Topics: Amino Acid Substitution; Animals; Binding Sites; CHO Cells; Copper; COS Cells; Cricetinae; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Electron Spin Resonance Spectroscopy; Factor VIII; Humans; Kinetics; Leupeptins; Ligands; Macromolecular Substances; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry, Atomic

Topics: Animals; Cells, Cultured; Coronary Vessels; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Intercellular Adhesion Molecule-1; Leupeptins; Multienzyme Complexes; NF-kappa B; Nitric Oxide; Oxygen; Proteasome Endopeptidase Complex; Rats

Topics: Animals; Ankyrins; Brain; Calpain; Cell Fractionation; Cysteine Proteinase Inhibitors; Erythrocytes; In Vitro Techniques; Leupeptins; Male; Molecular Weight; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Rats, Wistar

Topics: Antioxidants; Cell Movement; Cells, Cultured; Cysteine Proteinase Inhibitors; Epidermal Cells; Extracellular Matrix Proteins; Humans; Hypoglycemic Agents; Insulin; Keratinocytes; Leupeptins; NF-kappa B; Pyrrolidines; Thiocarbamates

Topics: Acetylcysteine; Breast Neoplasms; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; DNA Replication; Female; Histones; Hot Temperature; Humans; Leupeptins; Multienzyme Complexes; Nucleoproteins; Nucleosomes; Proteasome Endopeptidase Complex; Protein Biosynthesis; Transcription, Genetic; Tumor Cells, Cultured; Ubiquitins

Topics: Calpain; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cysteine Endopeptidases; HeLa Cells; Humans; Leupeptins; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine

Topics: Animals; Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cystine; Dithiothreitol; Glycosylation; Humans; Leupeptins; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Microsomes, Liver; Molecular Weight; Neoplasm Proteins; Protease Inhibitors; Protein Conformation; Protein Denaturation; Protein Folding; Protein Processing, Post-Translational; Sulfhydryl Reagents; Tumor Cells, Cultured; Tunicamycin

Topics: Amino Acid Isomerases; Animals; Brefeldin A; Carrier Proteins; Cattle; Cell Compartmentation; Centrifugation, Density Gradient; Cyclopentanes; Cysteine; DNA-Binding Proteins; Heat-Shock Proteins; Leupeptins; Ligands; Methionine; Molecular Weight; Protein Folding; Protein Synthesis Inhibitors; Tacrolimus; Tacrolimus Binding Proteins; Tropoelastin

Topics: Binding Sites; Blotting, Western; Cell Line; Epithelial Cells; Humans; Hydrolysis; Interleukin-8; Kinetics; Leupeptins; Lung; Promoter Regions, Genetic; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Animals; Cecum; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Kinetics; Leupeptins; Male; Multienzyme Complexes; Muscle Proteins; Muscle, Skeletal; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Transcription, Genetic; Ubiquitins

Topics: Animals; Antioxidants; Aorta; Cattle; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytokines; Dexamethasone; Endothelium, Vascular; Gene Expression; Humans; Interleukin-4; Leupeptins; NF-kappa B; Oncostatin M; P-Selectin; Peptides; Pyrrolidines; Sodium Salicylate; Thiocarbamates; Umbilical Veins

Topics: Acids; Amiloride; Animals; Autocrine Communication; Cell Nucleus; Culture Media; Cysteine Proteinase Inhibitors; Enzyme Induction; Genes, Reporter; Hydrogen-Ion Concentration; Leupeptins; Macrophages, Peritoneal; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates; Transcription, Genetic; Tumor Necrosis Factor-alpha

Topics: Calcimycin; Calpain; Carrier Proteins; Cell Death; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Intermediate Filament Proteins; Leupeptins; Nerve Tissue Proteins; Neuroblastoma; Neurofibrils; Oligopeptides; Tumor Cells, Cultured

Topics: Animals; Apolipoproteins B; Cells, Cultured; Disease Models, Animal; Hypobetalipoproteinemias; Leupeptins; Liver; Male; Rats; Shrews

Topics: Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Interleukin-3; Janus Kinase 2; Leupeptins; Mice; Milk Proteins; Multienzyme Complexes; Phosphoprotein Phosphatases; Proteasome Endopeptidase Complex; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Interleukin-3; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Ubiquitins; Vanadates

Topics: Acetylcysteine; Adenoviridae; Animals; Animals, Newborn; Cell Cycle; Cell Differentiation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Gene Expression Regulation; Keratinocytes; Leupeptins; Membrane Proteins; Mice; Mutation; Promoter Regions, Genetic; Protein Precursors; RNA, Messenger; Succinates; Transfection

Topics: 3T3 Cells; Animals; Apoptosis; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; G1 Phase; Heat-Shock Proteins; Immunosuppressive Agents; Leupeptins; Mice; Microtubule-Associated Proteins; Phosphorylation; Polyenes; Retinoblastoma Protein; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Tacrolimus Binding Proteins; Transcription, Genetic; Tumor Suppressor Proteins

Topics: Acetylcysteine; Apolipoproteins B; Biological Transport; Cell Membrane Permeability; Chromans; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leupeptins; Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Tumor Cells, Cultured; Vitamin E

Topics: Cells, Cultured; Chemokine CCL2; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Gene Expression Regulation; Humans; Interleukin-1; Leupeptins; Multienzyme Complexes; NF-kappa B; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

Topics: Acetylcysteine; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell-Free System; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; Glycine; Histocompatibility Antigens Class I; HLA-A Antigens; Humans; Leupeptins; Membrane Proteins; Mice; Molecular Sequence Data; Multienzyme Complexes; Proteasome Endopeptidase Complex; T-Lymphocytes, Cytotoxic; Time Factors; Viral Matrix Proteins

Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cyclin B; Leupeptins; Mitosis; Nocodazole; S Phase; Tubulin; Xenopus laevis

Topics: Carcinoma, Squamous Cell; Collagenases; Cysteine Proteinase Inhibitors; Gelatinases; Humans; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Oligopeptides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Animals; Burns; Culture Techniques; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Lactones; Leupeptins; Male; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tyrosine; Ubiquitins

Topics: Annexin A6; Clathrin; Coated Pits, Cell-Membrane; Cysteine Proteinase Inhibitors; Cytoskeleton; Endocytosis; Fibroblasts; Humans; Leupeptins; Lipoproteins, LDL; Lysosomes; Membrane Proteins; Microscopy, Fluorescence; Peptide Fragments; Protein Binding; Recombinant Proteins; Spectrin

Topics: Animals; Brain; Cattle; Cell Adhesion; Cell Line; Cysteine Endopeptidases; Drosophila Proteins; Endopeptidases; Fluorescent Antibody Technique; Genes, ras; Immunohistochemistry; Kinesins; Leupeptins; Multienzyme Complexes; Myosins; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Transfection; Ubiquitin Thiolesterase; Ubiquitins

Topics: Antineoplastic Agents; Clone Cells; Colony-Forming Units Assay; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Egg Proteins; Flow Cytometry; Formazans; Humans; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Ribonucleases; Tetrazolium Salts; Toxicity Tests; Tumor Cells, Cultured

Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats

Topics: Acetylcysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; Immediate-Early Proteins; Leupeptins; Milk Proteins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Receptors, Erythropoietin; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Tyrosine; Ubiquitins

Topics: Actinin; Actins; Apoptosis; Calpain; Caspases; Cell Communication; Cells, Cultured; Cellular Senescence; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dipeptides; Drug Synergism; Humans; Leupeptins; Multienzyme Complexes; Neutrophils; Phosphoproteins; Proteasome Endopeptidase Complex

Topics: Acetylcysteine; Antibiotics, Antineoplastic; Apoptosis; Calpain; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Multienzyme Complexes; Naphthalenes; Neoplasm Proteins; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; U937 Cells; Ubiquitins

Topics: Anaphase-Promoting Complex-Cyclosome; Animals; Aphidicolin; cdc25 Phosphatases; Cell Cycle Proteins; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p27; DNA Replication; Female; G2 Phase; Leupeptins; Ligases; Male; Maturation-Promoting Factor; Microtubule-Associated Proteins; Mitosis; Nuclear Proteins; Okadaic Acid; Ovum; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Recombinant Proteins; S Phase; Spermatozoa; Tumor Suppressor Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitins; Xenopus; Xenopus Proteins

Topics: Animals; Calpain; CCAAT-Enhancer-Binding Proteins; Cell Nucleus; CHO Cells; Cricetinae; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Gene Deletion; Hydroxymethylglutaryl-CoA Synthase; Leupeptins; Microsomes; Molecular Weight; Nuclear Proteins; Peptide Fragments; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Transfection

Topics: Animals; Apolipoproteins B; Biological Transport; Carrier Proteins; Cells, Cultured; CHO Cells; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Humans; Hydroxycholesterols; Leupeptins; Microsomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rats; RNA, Messenger; Transfection; Ubiquitins

Topics: Animals; Apoptosis; Base Sequence; Blotting, Western; Caspase 1; Cattle; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Primers; Down-Regulation; Glutathione; Leupeptins; Light; Lipid Peroxidation; Mice; Mice, Transgenic; Multienzyme Complexes; NF-kappa B; Oxidative Stress; Photoreceptor Cells; Proteasome Endopeptidase Complex

Topics: Acetylcysteine; Animals; Apolipoproteins A; Calnexin; Cells, Cultured; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Fabaceae; Hepatocytes; Hexosaminidases; Leupeptins; Mannosidases; Molecular Chaperones; Multienzyme Complexes; Papio; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Transfection; Ubiquitin

Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adipocytes; Animals; Calcium-Binding Proteins; Calpain; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Dexamethasone; DNA-Binding Proteins; Insulin; Leupeptins; Mice; Nuclear Proteins; Recombinant Proteins; Transcription Factors; Transfection

Topics: Amino Acid Sequence; Animals; Base Sequence; beta Catenin; Binding Sites; Cadherins; Cell Adhesion; Cell Line; Cell Membrane; Cell Polarity; Chloroquine; Cytoplasm; Cytoskeletal Proteins; Dogs; Endoplasmic Reticulum; Leupeptins; Macromolecular Substances; Molecular Sequence Data; Plasmids; Rats; Recombinant Fusion Proteins; Trans-Activators

Topics: Animals; Apolipoprotein B-100; Apolipoproteins B; Biomarkers; Cells, Cultured; Cricetinae; Dietary Fats, Unsaturated; Endoplasmic Reticulum, Rough; Fish Oils; Leupeptins; Lipoproteins, VLDL; Liver; Male; Oleic Acid; Phenanthrolines; Plant Oils; Protease Inhibitors

Topics: Base Sequence; Caco-2 Cells; Complement C3; DNA Primers; DNA-Binding Proteins; Genistein; Humans; I-kappa B Proteins; Interleukin-1; Intestinal Mucosa; Leupeptins; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Pyrrolidines; RNA, Messenger; Thiocarbamates; Tosyllysine Chloromethyl Ketone; Transfection

Topics: Animals; Blood-Brain Barrier; Blotting, Western; Calpain; Carrier Proteins; Cell Death; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Carriers; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gerbillinae; Hippocampus; Immunohistochemistry; Injections, Intravenous; Ischemic Attack, Transient; Leupeptins; Liposomes; Microfilament Proteins; Microscopy, Confocal; Neurons; Prosencephalon

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Calpain; Cell Line; Endopeptidases; Gene Expression Regulation; Humans; Leupeptins; Membrane Proteins; Molecular Sequence Data; Mutation; Peptide Fragments; Presenilin-1; Protease Inhibitors; Transfection

Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Bucladesine; Calpain; Cyclin B; Cyclin B1; Cysteine Proteinase Inhibitors; Dipeptides; Fluorouracil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketones; Leupeptins; Lovastatin; Nuclear Proteins; Protein Processing, Post-Translational; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Tumor Cells, Cultured

Topics: Adenomatous Polyposis Coli Protein; Animals; beta Catenin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Down-Regulation; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Leupeptins; Multienzyme Complexes; Mutation; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Phosphatase 2; Proto-Oncogene Proteins; Signal Transduction; Trans-Activators; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Wnt Proteins; Xenopus; Xenopus Proteins; Zebrafish Proteins

Topics: Animals; Apolipoproteins B; Biological Transport; Carrier Proteins; Chloroquine; CHO Cells; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Dithiothreitol; Endoplasmic Reticulum; HeLa Cells; Humans; Leupeptins; Lipoproteins; Liver; Mice; Transfection

Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Calpain; CHO Cells; Cricetinae; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Enzyme Inhibitors; Leupeptins; Peptide Fragments; Serine Endopeptidases

Topics: AIDS Dementia Complex; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Probes; Enzyme Activation; Fetus; Gene Expression; HIV-1; Humans; Leupeptins; Lipopolysaccharides; Macrophages; Microglia; Multienzyme Complexes; NF-kappa B; Phagocytosis; Proteasome Endopeptidase Complex; Tumor Necrosis Factor-alpha

Topics: Adolescent; Age Factors; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Camptothecin; Cell Cycle Proteins; Cells, Cultured; Child; Child, Preschool; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glioblastoma; Humans; I-kappa B Proteins; Leupeptins; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Phosphoric Monoester Hydrolases; Protease Inhibitors; Protein Serine-Threonine Kinases; Proteins; Radiation Tolerance; Recombinant Fusion Proteins; Topoisomerase I Inhibitors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

Topics: Acetylcysteine; Animals; Cell Line; Cricetinae; Cricetulus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Gene Expression Regulation, Enzymologic; Glucosephosphate Dehydrogenase; Immunoglobulin Constant Regions; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Inovirus; Isopropyl Thiogalactoside; Kinetics; Leupeptins; Multienzyme Complexes; Peptide Library; Proteasome Endopeptidase Complex; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection

Topics: Adenosine; Allopurinol; Animals; Antibodies; Calpain; Enzyme Precursors; Glutathione; Heart; Heart Transplantation; Hypothermia, Induced; Insulin; Leupeptins; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Time Factors

Topics: Acetylcysteine; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma; Cell Nucleus; Cysteine Proteinase Inhibitors; DNA Damage; DNA-Binding Proteins; Female; Fibrosarcoma; Humans; Leupeptins; Mitomycin; Oncogene Proteins, Viral; Papillomaviridae; Polymorphism, Genetic; Repressor Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms

Topics: Acetylcysteine; Adenosine Triphosphatases; Antibody Affinity; Cell Adhesion; Cell Differentiation; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; HL-60 Cells; Humans; Intercellular Adhesion Molecule-1; Leupeptins; Lymphocyte Function-Associated Antigen-1; Monocytes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Tretinoin; Ubiquitins

Topics: 3T3 Cells; Acetylcysteine; Animals; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Deletion; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Hemagglutinins; Humans; Leupeptins; Mice; Models, Genetic; Multienzyme Complexes; Mutagenesis; Osteosarcoma; Proliferating Cell Nuclear Antigen; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Time Factors; Transfection; Tumor Cells, Cultured; Ubiquitins

Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Base Sequence; Calpain; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Leupeptins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Protein Serine-Threonine Kinases; Thimerosal; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

Topics: Acetylcysteine; Ammonium Chloride; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Brefeldin A; Calpain; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; K562 Cells; Leucine; Leupeptins; Membrane Proteins; Protein Synthesis Inhibitors; Time Factors; Ubiquitins

Topics: BRCA1 Protein; Calpain; Carrier Proteins; Cell Nucleus; Cysteine Endopeptidases; Dactinomycin; Down-Regulation; Endopeptidases; Exportin 1 Protein; Gene Expression Regulation; Half-Life; Humans; Hydrolysis; Karyopherins; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Tumor Cells, Cultured

Topics: Anisomycin; Cell Cycle; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mitogen-Activated Protein Kinases

Topics: Animals; Blood; Cell Cycle Proteins; Cell Division; Cell Line; Cricetinae; Culture Media; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dual Specificity Phosphatase 1; Estradiol; Humans; Immediate-Early Proteins; Leucine; Leupeptins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutation; Nitrophenols; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Ubiquitins

Topics: Animals; beta Catenin; Binding Sites; Cadherins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dogs; Endopeptidases; Kinesins; Kinetics; L Cells; Leupeptins; Mice; Multienzyme Complexes; Myosins; Oligopeptides; Proteasome Endopeptidase Complex; ras Proteins; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transfection; Ubiquitin Thiolesterase; Ubiquitins

Topics: Acetic Acid; Acetyl-CoA C-Acetyltransferase; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cell Cycle; Cell Survival; CHO Cells; Cholesterol; Clone Cells; Cricetinae; Deuterium Oxide; Enzyme Activation; Fatty Acids, Unsaturated; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Synthase; Lactones; Leupeptins; Lovastatin; Mevalonic Acid; Peroxisomes; Phosphorylation; Simvastatin; Tritium

Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells; Vanadates

Topics: Acetylcysteine; Animals; Calcium-Binding Proteins; Calnexin; Calreticulin; Carrier Proteins; Cell Membrane; COS Cells; Culture Media; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochalasin B; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Half-Life; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Leupeptins; Membrane Proteins; Molecular Chaperones; Protein Disulfide-Isomerases; Recombinant Proteins; Ribonucleoproteins

Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Calcium-Binding Proteins; Calpain; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; fas Receptor; Humans; Jurkat Cells; Leupeptins; Oligopeptides; Poly(ADP-ribose) Polymerases; Recombinant Proteins; Tumor Necrosis Factor-alpha

Topics: 3T3 Cells; Adipocytes; Animals; Calpain; Cell Cycle Proteins; Cell Differentiation; Clone Cells; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Cytoplasm; Gene Expression Regulation; Genes, Immediate-Early; Kinetics; Leupeptins; Mice; Microtubule-Associated Proteins; Mitosis; Recombinant Proteins; Time Factors; Transfection; Triglycerides; Tumor Suppressor Proteins

Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Brefeldin A; Cell Nucleus; Cysteine Proteinase Inhibitors; DNA, Complementary; GPI-Linked Proteins; Humans; Leupeptins; Ligands; Melanoma; Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Signal Transduction; Subcellular Fractions; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha

Topics: Cell Line; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Intermediate Filament Proteins; Keratins; Leupeptins; Multienzyme Complexes; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Transfection; Ubiquitins

Topics: Alzheimer Disease; Ammonium Chloride; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line; Centrifugation, Density Gradient; Cysteine Proteinase Inhibitors; Dogs; Endopeptidases; Humans; Leupeptins; Membrane Proteins; Peptide Fragments; Precipitin Tests; Presenilin-1; Transfection

Topics: Alanine; Animals; Bovine papillomavirus 1; Cattle; Cell Line; Chlorocebus aethiops; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; DNA, Viral; Gene Dosage; Genome, Viral; Lactones; Leupeptins; Multienzyme Complexes; Mutagenesis, Site-Directed; Papilloma; Papillomavirus Infections; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Viral Proteins; Warts

Topics: Apolipoproteins B; Biological Transport; Carrier Proteins; Cell Line; Endoplasmic Reticulum; Humans; Leupeptins; Methaqualone; Ribosomes; RNA, Messenger

Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Apoptosis; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Cell Death; Crk-Associated Substrate Protein; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mitogen-Activated Protein Kinases; Mitosis; Multienzyme Complexes; Mutation; Oligopeptides; Peptide Fragments; Phosphoproteins; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Isoforms; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Aldehydes; Animals; Antigen Presentation; Calpain; Cathepsin B; Cells, Cultured; CHO Cells; Cricetinae; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endosomes; Histocompatibility Antigens Class I; Humans; Lectins, C-Type; Leupeptins; Lysosomes; Macrophages, Peritoneal; Mannans; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mucin-1; Multienzyme Complexes; Oxidation-Reduction; Peptide Fragments; Proteasome Endopeptidase Complex; Receptors, Cell Surface; Schiff Bases

Topics: Acetylcysteine; Acrylates; Amino Acid Chloromethyl Ketones; Apoptosis; Boronic Acids; Bortezomib; Calpain; Cathepsins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Drug Synergism; Genes, p53; Humans; Jurkat Cells; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells

Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Etoposide; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; U937 Cells

Topics: Animals; beta-Galactosidase; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cholesterol; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Leupeptins; Lovastatin; Oligopeptides; Peptide Hydrolases; Precipitin Tests; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Tricarboxylic Acids; Ubiquitins

Topics: Acetylcysteine; Animals; Cell Fractionation; Cell Line; Chick Embryo; Cricetinae; Cysteine Endopeptidases; Detergents; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Humans; Isoenzymes; Kidney; Leupeptins; Membrane Proteins; Mesocricetus; Mice; Multienzyme Complexes; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Conformation; Protein Kinase C; Protein Kinase C-theta; Rats; Recombinant Fusion Proteins; Sindbis Virus; Tumor Cells, Cultured; Ubiquitins

Topics: Animals; Blotting, Western; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell-Free System; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Egtazic Acid; Gangliosides; Ion Channels; Leupeptins; Membrane Proteins; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Mimicry; Oligomycins; Rats

Topics: Animals; Apoptosis; Cells, Cultured; Cysteine Endopeptidases; Cytokines; Enterocytes; Enzyme Inhibitors; Genistein; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Penicillamine; Proteasome Endopeptidase Complex; Protein Transport; Pyrrolidines; Rats; Recombinant Proteins; Thiocarbamates; Tosyllysine Chloromethyl Ketone; Up-Regulation

Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antiporters; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Calcium-Binding Proteins; Calreticulin; Cysteine Endopeptidases; Endoplasmic Reticulum; HLA-B7 Antigen; Humans; Immunoglobulin G; Immunoglobulins; Leupeptins; Membrane Transport Proteins; Multienzyme Complexes; Mutagenesis, Site-Directed; Polymorphism, Genetic; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Binding; Rabbits; Ribonucleoproteins; Serine; Tyrosine

Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Dithiothreitol; Flavonols; Humans; Hydrolysis; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leupeptins; Liver; Quercetin; RNA, Messenger; Tumor Cells, Cultured

Topics: Animals; Atorvastatin; Cattle; Caveolin 1; Caveolins; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cholesterol; Cholesterol, LDL; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Heptanoic Acids; HSP90 Heat-Shock Proteins; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leupeptins; Lipoproteins, LDL; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyrroles; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Up-Regulation

Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Apoptosis; Autoantigens; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Calpain; Carrier Proteins; Cell Cycle; Cell Fractionation; Cloning, Molecular; Colonic Neoplasms; Cysteine Proteinase Inhibitors; DNA, Complementary; Egtazic Acid; Enzyme Inhibitors; Gene Library; Humans; Leupeptins; Mammary Neoplasms, Animal; Mice; Molecular Sequence Data; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

Topics: Animals; Arginine; Bacterial Proteins; Cell Line; Colony Count, Microbial; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Half-Life; Leupeptins; Listeria monocytogenes; Membrane Proteins; Multienzyme Complexes; Mutation; Proteasome Endopeptidase Complex

Topics: Acetylcysteine; Adenosine Triphosphatases; Carrier Proteins; Cation Transport Proteins; Cell Line; Copper-Transporting ATPases; Cysteine Endopeptidases; Cytoskeleton; Fluorescent Antibody Technique; Humans; Leupeptins; Microscopy, Confocal; Microscopy, Electron; Multienzyme Complexes; Mutation; Proteasome Endopeptidase Complex; Tissue Distribution

Topics: Acetylcysteine; Adenosine Triphosphate; Antigens, Neoplasm; Cell Cycle; Cell Extracts; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Topoisomerases, Type II; DNA-Binding Proteins; HeLa Cells; Humans; Isoenzymes; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured

Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; HL-60 Cells; Humans; Leupeptins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oligopeptides; Tumor Cells, Cultured; Valinomycin

Topics: Acetylcysteine; Amino Acid Sequence; Cell Death; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; G2 Phase; Green Fluorescent Proteins; Humans; Huntingtin Protein; Inclusion Bodies; Leupeptins; Luminescent Proteins; Molecular Sequence Data; Multienzyme Complexes; Nerve Tissue Proteins; Nuclear Proteins; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Transfection; Ubiquitins

Topics: Acetylcysteine; Animals; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dendrites; DNA-Binding Proteins; Gene Expression; Leupeptins; Multienzyme Complexes; Neurons; Neuroprotective Agents; Oligopeptides; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Smad Proteins; Smad1 Protein; Superior Cervical Ganglion; Trans-Activators; Transcriptional Activation; Transfection; Transforming Growth Factor beta

Topics: alpha-Synuclein; Animals; Brain; Carrier Proteins; Cerebral Cortex; Cryoprotective Agents; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dimethyl Sulfoxide; Fetus; Genes, Reporter; Green Fluorescent Proteins; Humans; Immunohistochemistry; Inclusion Bodies; Intracellular Signaling Peptides and Proteins; Leupeptins; Luminescent Proteins; Mice; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Recombinant Fusion Proteins; Synucleins; Tumor Cells, Cultured

Topics: Acetylcysteine; Apoptosis; Base Sequence; Brain Neoplasms; Cysteine Proteinase Inhibitors; DNA Primers; Fas Ligand Protein; fas Receptor; Glioma; Humans; Leupeptins; Membrane Glycoproteins; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured

Topics: Animals; Annexin A6; Calpain; Carbocyanines; Cell Compartmentation; CHO Cells; Cricetinae; Endocytosis; Fluorescent Antibody Technique; Fluorescent Dyes; Genetic Vectors; Iodine Radioisotopes; Leupeptins; Lipoproteins, LDL; Lysosomes; Protein Transport; Spectrin; Subcellular Fractions; Transport Vesicles

Topics: Apoptosis; Blotting, Western; BRCA1 Protein; CDC2-CDC28 Kinases; Cell Cycle; Cyclin G; Cyclin G1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Humans; Leupeptins; Multienzyme Complexes; Paclitaxel; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

Topics: Animals; Brefeldin A; CHO Cells; Cricetinae; Cysteine Endopeptidases; Cytoplasm; Endoplasmic Reticulum; Leupeptins; Membrane Proteins; Mice; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; PrPC Proteins; Solubility; Tumor Cells, Cultured; Ubiquitin

Topics: Animals; beta Catenin; Calpain; CHO Cells; Cricetinae; Cytoskeletal Proteins; DNA-Binding Proteins; Leupeptins; Lymphoid Enhancer-Binding Factor 1; Phosphorylation; Proto-Oncogene Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Transcription, Genetic; Wnt Proteins; Zebrafish Proteins

Topics: Amanitins; Animals; Carrier Proteins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drosophila Proteins; Eukaryotic Initiation Factor-4E; Eye Proteins; Glycoproteins; Growth Cones; Leupeptins; Lipopolysaccharides; Multienzyme Complexes; Nerve Growth Factors; Netrin-1; Nucleic Acid Synthesis Inhibitors; Peptide Initiation Factors; Phosphatidylinositol 3-Kinases; Phosphoproteins; Proteasome Endopeptidase Complex; Protein Biosynthesis; Receptor Protein-Tyrosine Kinases; Retina; Semaphorin-3A; Tumor Suppressor Proteins; Ubiquitin; Xenopus

Topics: 3T3 Cells; Animals; Blotting, Western; Calcium; Calcium-Binding Proteins; Cell Division; Cell Line; Cysteine Proteinase Inhibitors; DNA, Complementary; Gene Expression Regulation; Genes, Dominant; Humans; Isoenzymes; Leupeptins; Mice; Phenotype; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; ras Proteins; Time Factors; Transfection

Topics: Acetylcysteine; Adipocytes; Animals; Calpain; Cell Differentiation; Cell Line; Cysteine Proteinase Inhibitors; Kinetics; Leupeptins; Nuclear Proteins; Peptide Hydrolases; Phosphoproteins; Proteasome Endopeptidase Complex; Proteins; Retinoblastoma-Like Protein p130

Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Calpain; Caspase 3; Caspases; Cell Cycle; Cell Line; Cyclin D; Cyclin D3; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; G1 Phase; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-KappaB Inhibitor alpha; Peptide Hydrolases; Plasmids; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Biosynthesis; Ribonucleases; RNA; RNA, Messenger; Spectrometry, Fluorescence; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Ubiquitin

Topics: Adenosine Triphosphate; Apolipoproteins; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Differentiation; Cell Line; Cell Membrane; Cholesterol; Cysteine Proteinase Inhibitors; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Immunoblotting; Leupeptins; Lipid Metabolism; Precipitin Tests; Protease Inhibitors; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors

Topics: Animals; Burns; Heart; Heart Diseases; Hemodynamics; In Vitro Techniques; Inflammation Mediators; Kinetics; Leupeptins; Myocardial Contraction; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha

Topics: Animals; Antioxidants; Breast Neoplasms; Cells, Cultured; Chelating Agents; Copper; Cysteine; Cysteine Proteinase Inhibitors; Ditiocarb; Female; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leupeptins; Mannitol; Molecular Structure; Oxidants; Oxidation-Reduction; Pyrrolidines; Rats; Recombinant Proteins; Thiobarbituric Acid Reactive Substances; Thiocarbamates; Tumor Suppressor Protein p53

Topics: Animals; Cell Line; CHO Cells; Connexins; Cricetinae; Cysteine Proteinase Inhibitors; Cytosol; Endoplasmic Reticulum; Gap Junctions; Heat-Shock Response; Leupeptins; Oxidation-Reduction; Peptide Hydrolases; Proteasome Endopeptidase Complex

Topics: Antigen-Antibody Complex; Base Sequence; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Cross-Linking Reagents; Gene Expression Regulation; Humans; Interleukin-8; Leupeptins; Macrophage Activation; Macrophage Inflammatory Proteins; Molecular Sequence Data; Monocytes; NF-kappa B; Receptors, IgG; RNA, Messenger; Salicylates; Tumor Cells, Cultured

Topics: Animals; Aorta, Abdominal; Blotting, Western; Cells, Cultured; Cholesterol, Dietary; Chromatography, Thin Layer; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Humans; Hypercholesterolemia; In Situ Hybridization; Leupeptins; Lipoproteins, LDL; Low Density Lipoprotein Receptor-Related Protein-1; Macromolecular Substances; Muscle, Smooth, Vascular; Polymers; Receptors, LDL; RNA, Messenger; Signal Transduction; Sterol Regulatory Element Binding Protein 2; Swine; Transcription Factors; Up-Regulation

Topics: Calpain; Cell Adhesion; Cyclic GMP; Dipeptides; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Humans; Leupeptins; Mast Cells; Nitric Oxide; Nitric Oxide Donors; Peroxynitrous Acid; Protein Binding; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Tumor Cells, Cultured

Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Arabidopsis Proteins; Benzamides; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 1; Death Domain Receptor Signaling Adaptor Proteins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fas Ligand Protein; Fatty Acid Desaturases; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leupeptins; Membrane Glycoproteins; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Peptides; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Blotting, Northern; Blotting, Western; BRCA1 Protein; Cell Cycle; Cell Division; Cell Survival; Collagen; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Down-Regulation; Drug Combinations; Enzyme Inhibitors; Extracellular Matrix; Genetic Vectors; Germ-Line Mutation; Humans; Immunoblotting; Laminin; Leupeptins; MAP Kinase Signaling System; Neuregulin-1; Phenotype; Phosphatidylinositol 3-Kinases; Phosphorylation; Polylysine; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteoglycans; Proto-Oncogene Proteins; Receptor, ErbB-2; RNA; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured

Topics: Animals; Cell Cycle; Cell Division; Cell Line; Cells, Cultured; Cyclin D1; Cyclin D2; Cyclin D3; Cyclins; Cysteine Endopeptidases; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; G1 Phase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HeLa Cells; Hexanones; Humans; Leupeptins; Lithium Chloride; Microscopy, Fluorescence; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Umbilical Veins

Topics: Cytokines; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Humans; I-kappa B Proteins; Leupeptins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Neoplasm Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Protein Kinase C; Pyrrolidinones; RNA-Binding Proteins; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha; Type C Phospholipases

Topics: Animals; Burns; Cysteine Proteinase Inhibitors; Cytokines; Female; I-kappa B Proteins; Leupeptins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Transport; Tumor Necrosis Factor-alpha; Wounds and Injuries

Topics: Acetates; Albumins; Apolipoproteins B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cholesterol; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Humans; Leupeptins; Lipid Metabolism; Lipoproteins, VLDL; Microsomes; Time Factors; Triglycerides; Tumor Cells, Cultured; Verapamil

Topics: Apoptosis; Arthritis, Rheumatoid; Calpain; Cells, Cultured; Cysteine Proteinase Inhibitors; Drug Synergism; Humans; Hydrogen Peroxide; Leupeptins; Synovial Membrane

Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Calpain; Cell-Free System; Endopeptidases; Hydrogen-Ion Concentration; Kinetics; Leupeptins; Molecular Sequence Data; Plasmodium falciparum; Protease Inhibitors; Protein Processing, Post-Translational; Protozoan Proteins; Vacuoles

Topics: Cell Survival; Cloning, Molecular; DNA Repair; Gene Expression Regulation, Neoplastic; Glioma; Humans; Leupeptins; Mutagenesis, Site-Directed; NF-kappa B; Phosphorylation; Radiation Tolerance; Transfection; Tumor Cells, Cultured; Vanadates

Topics: Antibodies; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interleukin-10; Leupeptins; Male; Phosphorylation; Phosphotyrosine; Prostatic Neoplasms; Protease Inhibitors; Proto-Oncogene Proteins c-rel; Signal Transduction; Staurosporine; Tissue Inhibitor of Metalloproteinase-1

Topics: Apolipoprotein B-100; Apolipoproteins B; Biological Transport; Calpain; Carcinoma, Hepatocellular; Cell Compartmentation; Cysteine Endopeptidases; Cytosol; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Antibody Technique; Golgi Apparatus; Humans; Leupeptins; Microsomes, Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Ubiquitin

Topics: Animals; Base Sequence; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA; DNA Primers; Electrophoretic Mobility Shift Assay; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Leupeptins; Male; Multienzyme Complexes; Nitrites; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

Topics: Animals; Cell Differentiation; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Leupeptins; Multienzyme Complexes; Myoblasts; Phosphofructokinase-2; Proteasome Endopeptidase Complex; Proteins; Ubiquitin

Topics: Actin Cytoskeleton; Adipocytes; Animals; Biological Transport; Calpain; Cell Line; Cell Membrane; Cysteine Proteinase Inhibitors; Glucose; Glucose Transporter Type 4; Insulin; Leupeptins; Monosaccharide Transport Proteins; Muscle Proteins; Phosphorylation; Protein Transport; Signal Transduction; Transport Vesicles

Topics: Apolipoprotein A-I; Apolipoproteins; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Bucladesine; Carbazoles; Cell Line; Cholesterol; Cloning, Molecular; Cysteine Proteinase Inhibitors; DNA, Complementary; Enzyme Inhibitors; Humans; Indoles; Kinetics; Leupeptins; Lipoproteins, HDL; Phospholipids; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

Topics: Acetylcysteine; alpha-Crystallin B Chain; Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Expression; Heat-Shock Response; Leupeptins; Multienzyme Complexes; Myocytes, Cardiac; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Rats

Topics: Amino Acid Sequence; Animals; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Cell Line, Tumor; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fatty Acids; Genetic Vectors; Humans; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Deletion

Topics: Animals; Apoptosis; Cell Line; Cell Nucleus; Cysteine Endopeptidases; Cytoplasm; Down-Regulation; Endoribonucleases; Interferon-alpha; Leupeptins; Mice; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Protein Transport; Tetradecanoylphorbol Acetate

Topics: Acetylcysteine; Animals; Apolipoproteins B; Cells, Cultured; Cysteine Endopeptidases; Diabetes Mellitus; Disease Models, Animal; Gerbillinae; Hepatocytes; Hypercholesterolemia; Hyperinsulinism; Hypertriglyceridemia; Insulin; Insulin Resistance; Leupeptins; Lipoproteins, VLDL; Liver; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex

Topics: Animals; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Carrier Proteins; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Hepatocytes; Leupeptins; Lipoproteins, VLDL; Liver Neoplasms, Experimental; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Rats; Symporters; Taurocholic Acid; Time Factors; Transfection; Triglycerides

Topics: alpha Catenin; Amino Acid Chloromethyl Ketones; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Caspase Inhibitors; Caspases; Cell Division; Cell Line, Tumor; Cell Nucleus; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Cytosol; Desmoplakins; DNA-Binding Proteins; G2 Phase; gamma Catenin; Humans; Inhibitor of Apoptosis Proteins; Leupeptins; Lymphoid Enhancer-Binding Factor 1; Microtubule-Associated Proteins; Neoplasm Proteins; Oligopeptides; Peptide Fragments; Proto-Oncogene Proteins c-myc; RNA, Messenger; Survivin; Trans-Activators; Transcription Factors; Transcriptional Activation

Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Bronchi; Cell Culture Techniques; Cell Division; Cell Line; Cyclin D1; Cyclin E; Cyclin G; Cyclin G1; Cyclins; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; G1 Phase; Humans; Immunoblotting; Leupeptins; Mutation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Threonine; Transcription, Genetic; Transfection; Tretinoin

Topics: Acetylcysteine; Antioxidants; Cell Cycle Proteins; Cell Line, Tumor; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; E2F1 Transcription Factor; E2F2 Transcription Factor; Glutathione; Humans; Leupeptins; Multienzyme Complexes; Osteosarcoma; Transcription Factors; Transcription, Genetic; Transfection

Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Calpain; Caspase Inhibitors; Cathepsins; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; HeLa Cells; Humans; Keratinocytes; Ketones; Leupeptins; Phospholipases A; Ultraviolet Rays

Topics: 14-3-3 Proteins; Cell Line; Cell Nucleus; Cysteine Proteinase Inhibitors; Cytoplasm; Enzyme Inhibitors; Histone Deacetylases; Humans; Leupeptins; Marine Toxins; Models, Biological; Mutation; Oxazoles; Peptide Hydrolases; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Biosynthesis; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine 3-Monooxygenase; Up-Regulation

Topics: Animals; Cardiomyopathies; Endotoxins; Glycoproteins; Heart; In Vitro Techniques; Inflammation; Injections, Intravenous; Leukocyte Rolling; Leupeptins; Male; Myocardial Contraction; Myocardium; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Septic; Tumor Necrosis Factor-alpha

Topics: Activating Transcription Factor 6; Animals; CHO Cells; Cricetinae; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Humans; Kidney; Leupeptins; Mice; Molecular Chaperones; NF-kappa B; NIH 3T3 Cells; Protease Inhibitors; Proteasome Endopeptidase Complex; Thapsigargin; Transcription Factors

Topics: Animals; Antibodies; Cell Cycle Proteins; Cyclin B; Cyclin B1; Cysteine Proteinase Inhibitors; Female; Fertilization in Vitro; Leupeptins; MAP Kinase Signaling System; Meiosis; Mice; Oocytes; Parthenogenesis; Polo-Like Kinase 1; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Subcellular Fractions; Ubiquitin

Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Insulinoma; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mice; Pancreatic Neoplasms; Proteasome Inhibitors; Rats; Signal Transduction; Tumor Suppressor Protein p53

Topics: Animals; Base Sequence; Corticosterone; Dexamethasone; DNA; Female; Hormone Antagonists; Leupeptins; Male; Melatonin; Mifepristone; NF-kappa B; Norepinephrine; Organ Culture Techniques; Pineal Gland; Pyrrolidines; Rats; Rats, Wistar; Receptors, Glucocorticoid; Serotonin; Thiocarbamates

Topics: Aminophenols; Antibiotics, Antineoplastic; Antimanic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cyclin D1; Cysteine Proteinase Inhibitors; Down-Regulation; Drug Resistance, Neoplasm; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Half-Life; Humans; Indoles; Leupeptins; Lithium Chloride; Maleimides; Mitochondria; NF-kappa B; Paclitaxel; Proteasome Inhibitors; Sirolimus

Topics: Animals; Cell Line; Cysteine Proteinase Inhibitors; Golgi Apparatus; Leucine; Leupeptins; Melanins; Melanocytes; Mice; Monophenol Monooxygenase; Oxidoreductases; Phenylthiourea; Proteasome Inhibitors

Topics: Acetylcysteine; Alkaloids; Blotting, Western; Cell Line; Cell Membrane; Cysteine Proteinase Inhibitors; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Inhibitors; Glycosylation; Green Fluorescent Proteins; Humans; Immunoprecipitation; Leupeptins; Long QT Syndrome; Mutation; Potassium Channels; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ribonucleases; Subcellular Fractions; Time Factors; Transfection; Ubiquitin

Topics: Animals; Aorta, Thoracic; Cell Line; Cells, Cultured; Dependovirus; DNA, Viral; Endothelial Cells; Genetic Therapy; Genetic Vectors; Humans; Leupeptins; Mice; Muscle, Smooth, Vascular; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Inbred WKY; Saphenous Vein; Serotyping; Transduction, Genetic

Topics: Animals; Cell Nucleus Structures; Cells, Cultured; Colchicine; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochalasin B; Female; Leupeptins; Meiosis; Oocytes; Parthenogenesis; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Ubiquitin

Topics: Calpain; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Leupeptins; Mammalian orthoreovirus 3; Receptors, Polymeric Immunoglobulin; Ultraviolet Rays; Up-Regulation

Topics: Animals; Apoptosis; Blotting, Western; Calcium; Calpain; Cathepsin D; Cell-Free System; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Immunoenzyme Techniques; In Situ Nick-End Labeling; Leupeptins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Organ Culture Techniques; Photoreceptor Cells, Vertebrate; Reactive Oxygen Species; Retinal Degeneration; Signal Transduction

Topics: Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Genes, Reporter; Genome, Viral; Hepacivirus; Humans; Immunoprecipitation; Leupeptins; Lipids; Liver; Liver Neoplasms; Oleic Acid; Plasmids; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Transfection; Triglycerides; Viral Nonstructural Proteins

Topics: Animals; Caffeic Acids; Cell Line; Chickens; Enterococcus; Enzyme Inhibitors; Genistein; I-kappa B Proteins; Klebsiella pneumoniae; Leupeptins; Macrophage Activation; Macrophages; NF-kappa B; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Poly I-C; Poultry Diseases; Protein-Tyrosine Kinases; RNA, Double-Stranded; Signal Transduction

Topics: Animals; Apolipoprotein A-I; Apolipoproteins B; Caprylates; Carrier Proteins; Cells, Cultured; Chickens; Cholesterol, VLDL; Cysteine Proteinase Inhibitors; Down-Regulation; Fatty Acid Synthases; Hepatocytes; Hydroxymethylglutaryl CoA Reductases; Leupeptins; Lipoproteins, VLDL; Male; Palmitic Acid; Triglycerides

Topics: alpha-MSH; Animals; Blotting, Western; Calcium-Binding Proteins; Calpain; Cell Differentiation; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Hormones; Indolequinones; Leupeptins; Melanins; Melanocytes; Melanoma, Experimental; Mice; Monophenol Monooxygenase; RNA, Messenger; Tumor Cells, Cultured

Topics: Animals; Carrier Proteins; CHO Cells; Cricetinae; Culture Media; Fatty Acids; Leupeptins; Oleic Acid; Perilipin-1; Phosphoproteins; Proteasome Endopeptidase Complex; Recombinant Proteins; Transfection; Triglycerides; Ubiquitin

Topics: Animals; Aspartic Acid Endopeptidases; Biotransformation; Catalysis; Leupeptins; Mutation; Pepstatins; Plasmodium falciparum; Protein Structure, Tertiary; Protozoan Proteins; Recombinant Fusion Proteins

Topics: Animals; Cell Line, Tumor; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Growth Factor; Extracellular Matrix; Fibroblasts; Glycoproteins; Humans; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leupeptins; Mice; Mitogen-Activated Protein Kinase 3; Peptides; Protein Serine-Threonine Kinases; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction

Topics: Apolipoproteins B; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Cytoplasm; Humans; Leupeptins; Lipids; Lipoproteins, VLDL; Liver Neoplasms; Proteasome Endopeptidase Complex

Topics: Animals; Cell Communication; Connexin 43; Diabetes Mellitus, Experimental; Electrophysiology; Gap Junctions; Heart; Immunoblotting; Immunohistochemistry; Leupeptins; Male; Microscopy, Electron; Myocardium; Phosphorylation; Protein Isoforms; Protein Kinase C; Rats; Rats, Wistar; Streptozocin

Topics: Asthma; Boronic Acids; Bortezomib; Cell Line; Chemokine CCL11; Chemokine CCL26; Chemokines, CC; Drug Synergism; Enzyme Inhibitors; Fibroblasts; Humans; Hypersensitivity; Immunoblotting; Interleukin-4; Leupeptins; Lung; Mitogen-Activated Protein Kinases; NF-kappa B; Pyrazines; Recombinant Proteins; STAT6 Transcription Factor; Tumor Necrosis Factor-alpha

Topics: Animals; beta-Crystallin A Chain; beta-Crystallin B Chain; beta-Crystallins; Cricetinae; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Heat-Shock Proteins; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Isoelectric Focusing; Leupeptins; Luciferases; Molecular Chaperones; Mutation; Protein Folding; Solubility

Topics: Adenoviruses, Human; Amino Acid Sequence; Antigen Presentation; ATP-Binding Cassette Transporters; Bacterial Proteins; Brefeldin A; Cell Line; Cell Line, Transformed; Clone Cells; Cytosol; Histocompatibility Antigens Class I; Humans; Immediate-Early Proteins; Lactic Acid; Leupeptins; Microspheres; Molecular Sequence Data; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteasome Inhibitors; Signal Transduction; Viral Proteins

Topics: Acrylates; Animals; Apoptosis; Calpain; Caspase 12; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Gene Expression Regulation; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Kidney Tubules, Proximal; Leupeptins; Molecular Chaperones; Oligopeptides; Proteins; Proteinuria; Rats; Serum Albumin, Bovine; Stress, Physiological

Topics: Amine Oxidase (Copper-Containing); Animals; Burns; Cysteine Proteinase Inhibitors; Disease Models, Animal; Intestinal Mucosa; Intestines; Leupeptins; Male; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrrolidines; Random Allocation; Rats; Rats, Wistar; Sepsis; Thiocarbamates; Tumor Necrosis Factor-alpha; Ubiquitin

Topics: Animals; Blotting, Western; Cells, Cultured; Cholesterol; Cricetinae; Cricetulus; Cysteine Proteinase Inhibitors; Gene Expression; Immunohistochemistry; Immunoprecipitation; Leupeptins; Membrane Microdomains; Mice; Mice, Neurologic Mutants; Mutant Proteins; Myelin Proteolipid Protein; Nerve Tissue Proteins; Oligodendroglia; Protein Transport; Subcellular Fractions; Time Factors; Transfection

Topics: Animals; Calpain; Cations, Monovalent; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Glycogen Synthase; Glycogen Synthase Kinase 3; Hepatocytes; Leupeptins; Lithium Chloride; Liver Glycogen; Male; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger

Topics: Angiogenesis Inhibitors; Apoptosis; Arginine; Calcium; Calpain; Caspases; Cell Line; Cell Survival; Chelating Agents; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Leupeptins; Membrane Potential, Mitochondrial; Naphthoquinones; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oligopeptides; Signal Transduction; Time Factors

Topics: Acetylcysteine; Calpain; Catenins; Cell Adhesion Molecules; Cell Aggregation; Cell Death; Cell Line, Tumor; Delta Catenin; Dipeptides; Humans; Ischemia; Leupeptins; Neuroblastoma; Phosphoproteins

Topics: Analysis of Variance; Atherosclerosis; Blotting, Western; Cells, Cultured; Cholesterol Esters; Coronary Vessels; Down-Regulation; Gene Expression Regulation; Humans; Leupeptins; Lipoproteins, LDL; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Statistics, Nonparametric; Sterol Regulatory Element Binding Proteins

Topics: Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fluoresceins; Glucose Oxidase; Humans; Hydrogen Peroxide; Inclusion Bodies; Keratin-18; Keratin-8; Leupeptins; Liver Diseases; Oxidative Stress; Phenylbutyrates; Proteasome Inhibitors; Tumor Cells, Cultured

Topics: Actins; Apoptosis; Bacterial Toxins; Caspases; Cathepsins; Cell Cycle; Enterotoxins; Enzyme Activation; Glucosides; Glycosyltransferases; HT29 Cells; Humans; Leupeptins; Models, Biological; Protein Processing, Post-Translational; rho GTP-Binding Proteins; Tumor Suppressor Protein p53

Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Blotting, Western; Calcimycin; Calpain; Cell Differentiation; Cell Nucleus; Cells, Cultured; Chromones; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Ionophores; Leupeptins; Mice; Microscopy, Confocal; Morpholines; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Signal Transduction; Time Factors

Topics: Blood Platelets; Calcium; Calcium-Transporting ATPases; Calpain; Cell Membrane; Collagen; Dipeptides; Enzyme Activation; Humans; Leupeptins; Platelet Activation; Thrombin

Topics: Animals; Babesia bovis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Erythrocytes; Leucine; Leupeptins

Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Line; Connexin 43; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Gap Junctions; Humans; Immunohistochemistry; Leupeptins; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; von Willebrand Factor

Topics: Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Doxorubicin; Gene Expression Regulation; Humans; Immunoblotting; Leupeptins; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Antibodies; Apoptosis; Brain; Case-Control Studies; Cells, Cultured; Cerebellum; Drug Interactions; Gene Expression Regulation; Humans; Leupeptins; Mice; Neurons; Oligopeptides; Postmortem Changes; Sp3 Transcription Factor; Sp4 Transcription Factor; tau Proteins; Time Factors; Transfection

Topics: Cell Line; Cell Nucleus; Chemokine CCL2; Chemokine CCL5; Cytoplasm; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mycobacterium bovis; NF-kappa B; Nitriles; Protein Transport; Sulfasalazine; Sulfones; Toll-Like Receptor 2

Topics: Animals; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Calpain; Caspase Inhibitors; Caspases; Cells, Cultured; Cysteine Proteinase Inhibitors; Disease Models, Animal; Enzyme Activation; Estradiol; Female; Hydrogen Peroxide; Leupeptins; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Ovariectomy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Severity of Illness Index

Topics: Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Monocytes; Oxidative Stress; Protease Inhibitors; Proteasome Endopeptidase Complex; Ritonavir; Tocopherols; Tocotrienols; Tumor Suppressor Protein p53; Tyrosine; Vitamin E

Topics: Antioxidants; Antipyrine; Apoptosis; Ascorbic Acid; Blotting, Western; Boronic Acids; Bortezomib; Butylated Hydroxyanisole; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Coumarins; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Edaravone; Endometrial Neoplasms; Ergothioneine; Female; Humans; Leupeptins; Oligopeptides; Proteasome Inhibitors; Pyrazines; Ubiquitin; Vitamin E; Vitamins

Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Dipeptides; Down-Regulation; Glucose; Half-Life; Hippocampus; Insulin; Leupeptins; Male; Nerve Tissue Proteins; Neurons; PC12 Cells; Rats; Rats, Sprague-Dawley; Time Factors

Topics: Apoptosis; Autophagy; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Humans; Inclusion Bodies; Keratins; Leupeptins; Organelles; Proteasome Inhibitors; Protein Synthesis Inhibitors

Topics: Animals; Antineoplastic Agents; Bronchi; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytokines; Endopeptidases; Gene Expression Regulation, Leukemic; Humans; Immunoblotting; Immunoprecipitation; Leukemia, Promyelocytic, Acute; Leupeptins; Oncogene Proteins, Fusion; Protein Processing, Post-Translational; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transfection; Tretinoin; Ubiquitin Thiolesterase; Ubiquitin-Activating Enzymes; Ubiquitins

Topics: alpha-Crystallin B Chain; Animals; Apoptosis; Calcium Signaling; Calpain; Caspase 3; Cell Line; Cell Nucleus; Cytochromes c; Egtazic Acid; Hydrogen Peroxide; Leupeptins; Myocytes, Cardiac; Oligopeptides; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Poly(ADP-ribose) Polymerases; Protein Transport; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Time Factors; Tubulin

Topics: Acrylates; Calpain; Cells, Cultured; Dipeptides; Glycoproteins; Humans; Interleukin-1alpha; Leupeptins; Polymorphism, Genetic; RNA, Messenger

Topics: Amino Acid Sequence; Animals; Calpain; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Intracellular Space; Leupeptins; Molecular Sequence Data; Neurons; Protein Processing, Post-Translational; Protein Stability; Protein Transport; Rats; Stem Cells; Subcellular Fractions; tat Gene Products, Human Immunodeficiency Virus

Topics: AMP-Activated Protein Kinases; Animals; Aorta; Calpain; Cattle; Cells, Cultured; Cytoskeletal Proteins; Dipeptides; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Hydrogen Peroxide; Leupeptins; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Interaction Mapping; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Vascular Endothelial Growth Factor A

Topics: Amacrine Cells; Analysis of Variance; Animals; Blotting, Western; Calpain; Cell Death; Cysteine Proteinase Inhibitors; Dipeptides; Immunohistochemistry; In Situ Nick-End Labeling; Leupeptins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retina

Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine

Topics: Administration, Oral; Animals; Apolipoprotein B-100; Cell Line, Tumor; Cell-Free System; Cricetinae; Cysteine Proteinase Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fructose; Gene Expression; Hepatocytes; Humans; I-kappa B Kinase; I-kappa B Proteins; Imidazoles; Inflammation; Leupeptins; Lipid Metabolism; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Mesocricetus; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Protein Kinase Inhibitors; Quinoxalines; Transfection; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Activating Transcription Factor 6; Animals; Apolipoprotein B-100; Cell Line; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoribonucleases; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Glucosamine; Heat-Shock Proteins; Humans; Leupeptins; Membrane Proteins; Phosphorylation; Protein Serine-Threonine Kinases; RNA; Signal Transduction; Time Factors

Topics: Analysis of Variance; Apoptosis Regulatory Proteins; Autophagy; Caspase 3; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Fluoresceins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neuroblastoma; Oncogene Protein v-akt; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; TOR Serine-Threonine Kinases

Topics: Animals; Ataxin-3; Blotting, Western; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cysteine Proteinase Inhibitors; Gene Expression; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Leupeptins; Machado-Joseph Disease; Molecular Chaperones; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Transfection

Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Escherichia coli; Escherichia coli Proteins; Glutathione Transferase; Half-Life; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Okadaic Acid; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Recombinant Proteins; Serine; Sulfotransferases; Threonine; Transfection; Two-Hybrid System Techniques

Topics: Animals; Antimalarials; Calpain; Drug Evaluation, Preclinical; Erythrocytes; HeLa Cells; Humans; Leupeptins; Parasitemia; Plasmodium falciparum; Protozoan Proteins; Schizonts; Trophozoites

Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Calpain; Cell Movement; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dyneins; Embryo, Mammalian; Female; Fibroblasts; Gene Expression Regulation, Developmental; Leucine; Leupeptins; Lissencephaly; Mice; Mice, Knockout; Microtubule-Associated Proteins; Models, Neurological; Neurons; Phenotype; Pregnancy

Topics: Animals; Antimalarials; Aspartic Acid Endopeptidases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Hemoglobins; Hydrolysis; Leupeptins; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Protease Inhibitors

Topics: Animals; Apoptosis; Cartilage, Articular; Caspase 8; Cells, Cultured; Chondrocytes; Dogs; Female; Homeostasis; Hypoxia; JNK Mitogen-Activated Protein Kinases; Leupeptins; Membrane Potential, Mitochondrial; Osteoarthritis; Proteasome Inhibitors; Reactive Oxygen Species; Synovial Fluid; TNF-Related Apoptosis-Inducing Ligand; Ubiquitinated Proteins

Topics: Acetylcysteine; Animals; Binding Sites; Brefeldin A; Chlorocebus aethiops; COS Cells; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Glycosylation; Leupeptins; Membrane Transport Modulators; Protein Structure, Tertiary; Protein Transport; Quinones; Sequence Deletion; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sesquiterpenes; Structure-Activity Relationship; Transfection

Topics: Antineoplastic Agents; Brain Neoplasms; Cell Culture Techniques; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Glioma; Humans; Leupeptins; Neoplastic Stem Cells; Phenotype; Proteasome Endopeptidase Complex; Reproducibility of Results

Topics: Acrylates; Animals; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Electrophoresis, Polyacrylamide Gel; Immunoenzyme Techniques; In Situ Nick-End Labeling; Leupeptins; Mitochondria; Photoreceptor Cells, Vertebrate; Rats; Rats, Mutant Strains; Retinal Degeneration

Topics: Animals; Autolysis; Blotting, Western; Calpain; Cell Fractionation; Cytosol; Disease Models, Animal; Dogs; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Leupeptins; Male; Muscle, Skeletal; Myocardial Reperfusion Injury; Myocardium; Oligopeptides; Rabbits; Rats; Rats, Sprague-Dawley

Topics: Apolipoproteins B; Codon, Nonsense; Cysteine Proteases; Cysteine Proteinase Inhibitors; Hep G2 Cells; Humans; Hypobetalipoproteinemia, Familial, Apolipoprotein B; Leupeptins; Protein Folding; Protein Transport

Topics: Acrosome Reaction; Animals; Blotting, Western; Calcium-Binding Proteins; Calpain; Cytoskeleton; Dipeptides; Guinea Pigs; Leupeptins; Male; Microscopy, Electron; Spectrin; Sperm Capacitation; Spermatozoa

Topics: Acetylcysteine; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Nucleolus; Checkpoint Kinase 1; Cyclin-Dependent Kinases; Cyclins; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; Leucine; Leupeptins; Nuclear Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin

Topics: Animals; Brain; Cell Differentiation; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Intracellular Signaling Peptides and Proteins; Leupeptins; MAP Kinase Signaling System; Neural Stem Cells; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; RNA, Small Interfering

Topics: Animals; beta-N-Acetylhexosaminidases; Cysteine Proteinase Inhibitors; Cytoplasmic Vesicles; HeLa Cells; Humans; Leupeptins; Lipid Metabolism; Membrane Proteins; Mice; Perilipin-2; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Transport; Proteolysis; RNA, Small Interfering

Topics: Acrylates; Base Sequence; Binding Sites; Calcium Signaling; Computer Simulation; Cysteine Proteinase Inhibitors; DNA Primers; Glycoproteins; HEK293 Cells; Humans; Leupeptins; Ligands; Models, Molecular; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; Structural Homology, Protein

Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination

Topics: Adenine; Animals; Autophagy; Carboxylic Ester Hydrolases; Cycloheximide; Green Fluorescent Proteins; HEK293 Cells; Humans; Leupeptins; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Protein Structure, Tertiary; Proteolysis; Recombinant Fusion Proteins

Topics: Antimalarials; Calpain; Cell Proliferation; Chromatography; Cysteine Proteinase Inhibitors; Flow Cytometry; HeLa Cells; Humans; Leupeptins; Magnetic Resonance Spectroscopy; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship

Topics: Acrylates; Calpain; Catalysis; Cell Line; Cysteine Proteinase Inhibitors; Dipeptides; Gelatin; Humans; Inhibitory Concentration 50; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Oligopeptides; Phenyl Ethers; Troponin I

Topics: Animals; Bacteriophages; Cell Line; Cell Line, Tumor; Dependovirus; Fluorescent Antibody Technique; Humans; Leupeptins; Mice; Proteasome Endopeptidase Complex

Topics: Calpain; Cell Cycle; Cell Nucleolus; Coiled Bodies; HeLa Cells; Humans; Leupeptins; Nuclear Proteins; Proteolysis

Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Calpain; Cysteine Proteinase Inhibitors; Excitatory Postsynaptic Potentials; Gene Expression; Heterozygote; Leupeptins; Lissencephaly; Mice; Mice, Mutant Strains; Microtubule-Associated Proteins; Miniature Postsynaptic Potentials; Mutation; Proteolysis; Pyramidal Cells; Spectrin

Topics: Animals; Calpain; Cell Movement; Cells, Cultured; Contractile Proteins; Cysteine Proteinase Inhibitors; Cytoskeleton; Embryo, Mammalian; Fibroblasts; Filamins; Focal Adhesions; Immunohistochemistry; Leupeptins; Luminescent Proteins; Mice; Mice, Knockout; Microfilament Proteins; Microscopy, Fluorescence; Microtubules; Models, Biological; Myosin Type II; RNA Interference; Talin; Vimentin

Topics: Acrylates; Animals; Animals, Newborn; Calcium Signaling; Calpain; Cell Membrane Permeability; Cells, Cultured; Cytoskeleton; Dipeptides; Leupeptins; Nerve Degeneration; Neurofilament Proteins; Neurons; Neurotoxins; Phospholipases A2; Presynaptic Terminals; Rats; Rats, Wistar; Snake Venoms; Spectrin; Spider Venoms

Topics: Amides; Antimalarials; Dipeptides; HeLa Cells; Humans; Leupeptins; Plasmodium falciparum

Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Down-Regulation; Drug Synergism; Humans; Leupeptins; Liver Neoplasms; Molecular Targeted Therapy; Niacinamide; Oligopeptides; Phenylurea Compounds; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sorafenib

Topics: Apoptosis; bcl-2-Associated X Protein; Cell Division; Cell Line, Tumor; Humans; Leupeptins

Topics: Animals; Blotting, Western; Calpain; Cell Adhesion; Cell Movement; Cell Shape; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytoskeleton; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Leukocyte Common Antigens; Leupeptins; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Paxillin; Phosphorylation; Proteolysis; src-Family Kinases; Time-Lapse Imaging

Topics: Animals; Apoptosis; Calcium-Binding Proteins; Calpain; Cell Survival; Cells, Cultured; Cysteine; Dipeptides; Endoplasmic Reticulum Stress; Hippocampus; Leupeptins; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Spectrin

Topics: Actins; Blood Proteins; Calpain; Candida albicans; Cell Line; Chromones; Cytochalasin D; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Galectin 3; Galectins; Gingiva; Humans; Leupeptins; Morpholines; Phosphoinositide-3 Kinase Inhibitors

Topics: Animals; Anisomycin; Chick Embryo; Ganglia, Spinal; Gene Expression Regulation, Developmental; Growth Cones; Laminin; Leupeptins; Myelin Proteins; Nogo Proteins; Polylysine; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Recombinant Proteins; rhoA GTP-Binding Protein; Signal Transduction; Tissue Culture Techniques

Topics: Animals; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Induced Pluripotent Stem Cells; Leupeptins; Long QT Syndrome; Male; Mice; Mutation; Myocytes, Cardiac; Phenotype; Protein Transport

Topics: Adenine; Adenosine Diphosphate; Autophagy; Endocytosis; Hep G2 Cells; Hepatocytes; Humans; Leupeptins; Lipase; Microtubule-Associated Proteins; Protein Isoforms; Receptors, Purinergic P2; RNA Interference; RNA, Small Interfering; Time Factors

Topics: Animals; Binge Drinking; Calpain; Cardiomyopathies; Caspase 3; Cathepsin B; Cathepsin L; Creatine Kinase, MB Form; Cysteine Proteinase Inhibitors; Cytochromes c; Disease Models, Animal; Humans; Immunohistochemistry; Leupeptins; Male; Myocardium; Nerve Tissue Proteins

Topics: Animals; Calcium; Calpain; Cysteine Proteinase Inhibitors; Leupeptins; Male; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Plasmodium chabaudi; Plasmodium falciparum; Protozoan Proteins; Spectrometry, Fluorescence

Topics: Adenocarcinoma; Animals; Carcinogenesis; Caspases; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclins; Dependovirus; Female; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Leupeptins; Mice; Mice, Knockout; Mice, Nude; Signal Transduction; Ubiquitin; Ubiquitin-Conjugating Enzymes; Xenograft Model Antitumor Assays

Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Amyloid Precursor Protein Secretases; Dipeptides; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Leupeptins; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Mutation; Protein Structure, Tertiary; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Calpain; Cathepsin L; Cattle; Cell Line, Tumor; Cells, Cultured; Humans; L-Lactate Dehydrogenase; Leupeptins; Peptide Fragments; Proteolysis; Rats; Ubiquitination

Topics: Animals; Antibodies; Apoptosis; Cell Line, Transformed; Cell Proliferation; Enzyme Inhibitors; Humans; Leupeptins; Lipopolysaccharides; Mice; Microglia; Nerve Tissue Proteins; Neuroprotective Agents; NF-kappa B; Nitrites; Phagocytosis; Photoreceptor Cells; Proteasome Endopeptidase Complex; RNA, Messenger; Signal Transduction

Topics: Amino Acid Chloromethyl Ketones; Animals; Benzothiazoles; Cardiotonic Agents; Caspase 3; Caspase Inhibitors; Cell Hypoxia; Chlorides; Down-Regulation; ErbB Receptors; Lapatinib; Leupeptins; Myocytes, Cardiac; Organometallic Compounds; Phosphorylation; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Multimerization; Pyridines; Quinazolines; Rats; Receptor, ErbB-2; RNA, Messenger; Thiones; Tyrphostins; Zinc Compounds

Topics: Bortezomib; Cell Membrane; Drug Discovery; Ether-A-Go-Go Potassium Channels; Gene Expression; HEK293 Cells; High-Throughput Screening Assays; Humans; Intracellular Space; Leupeptins; Mutation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Interaction Domains and Motifs; Protein Isoforms; Protein Transport; Schizophrenia

Topics: Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Antibody Technique; L-Lactate Dehydrogenase; Leupeptins; Microtubule-Associated Proteins; Mitochondria; Necrosis; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Retinal Neurons; Time Factors

Topics: Animals; Calcium; Calpain; Cell Death; Cells, Cultured; Hippocampus; Leupeptins; Neurons; Protease Inhibitors; Proteolysis; Rats; Rats, Wistar; Receptor, trkB; Status Epilepticus

Topics: Animals; Calcineurin; Calcium; Calcium Signaling; Calmodulin; Calpain; Cell Death; Cell Line; Cell Survival; Dynamins; Ferric Compounds; Hippocampus; Iron; Iron Overload; Leupeptins; Mice; Mitochondria; Neurons; Quaternary Ammonium Compounds; Sulfonamides

Topics: Chromosomes, Human, Pair 8; Genes, myc; Genetic Loci; Genetic Predisposition to Disease; Hodgkin Disease; Humans; Leupeptins; Polymorphism, Single Nucleotide; Prognosis; RNA, Long Noncoding; Survival Analysis

Topics: Animals; Apoptosis Inducing Factor; Calpain; Gene Expression Regulation; Glucose; Humans; Leupeptins; Mice; Oxygen; Retinal Ganglion Cells; Retinal Necrosis Syndrome, Acute

Topics: Actins; Animals; Calpain; Cardiomyopathies; Disease Models, Animal; Dystrophin; Gene Expression; Leupeptins; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Myocardium; Myosins; Proteasome Endopeptidase Complex; Proteolysis; Sepsis; TOR Serine-Threonine Kinases; Ubiquitin

Topics: A549 Cells; Animals; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspase 12; Caspase 8; Caspase 9; Cell Proliferation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; fas Receptor; Humans; Ink; Leupeptins; Lung Neoplasms; Mitochondria; Oligopeptides; Proline; Proto-Oncogene Proteins c-bcl-2; Sepia; Thiocarbamates; Transcription Factor CHOP

Topics: Calnexin; Calreticulin; ERG1 Potassium Channel; HEK293 Cells; Humans; Leupeptins; Long QT Syndrome; Molecular Chaperones; Mutation; Patch-Clamp Techniques; Propranolol; Protein Transport

Topics: Apoptosis; Calpain; Cells, Cultured; Humans; Imidazoles; Indoles; Leupeptins; Lung Transplantation; Necrosis; Phosphorylation; Primary Graft Dysfunction; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Death Domain; Reperfusion Injury; Signal Transduction; STAT3 Transcription Factor

Topics: Animals; Apoptosis; Beclin-1; Calpain; Caspases; Cell Line; Cell Survival; Cellular Senescence; Glutamic Acid; HeLa Cells; Hippocampus; Humans; Leupeptins; Mice; Neurons; NIH 3T3 Cells; Oxidative Stress; Reactive Oxygen Species

Topics: Adult; Clinical Decision-Making; Diagnosis, Differential; Disease Management; Female; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Leupeptins; Lymphoma, Non-Hodgkin; Male; Middle Aged

Topics: Antineoplastic Agents; Biological Transport, Active; Bortezomib; HEK293 Cells; Humans; Leupeptins; Oligopeptides; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Ubiquitination

Topics: Amino Acid Chloromethyl Ketones; Animals; Antiviral Agents; Azoles; Chlorocebus aethiops; Coronavirus 3C Proteases; Drug Evaluation, Preclinical; Enzyme Assays; Fluorescence Resonance Energy Transfer; High-Throughput Screening Assays; Isoindoles; Leupeptins; Organoselenium Compounds; Peptidomimetics; Reproducibility of Results; RNA-Binding Proteins; SARS-CoV-2; Small Molecule Libraries; Vero Cells; Viral Nonstructural Proteins

Topics: Animals; Apoptosis; Brain; Calcium; Calcium Signaling; Calpain; Cysteine Proteinase Inhibitors; Dipeptides; Isoenzymes; Leupeptins; Male; Mitochondria; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Molecular Weight; Muscle Proteins; Phosphorylation; Protein Transport; Rats

Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Diseases; Atherosclerosis; ATP Binding Cassette Transporter 1; Calpain; Cholesterol; Cysteine Proteinase Inhibitors; Disease Models, Animal; Gene Expression Regulation; Leupeptins; Lipid Metabolism; Liver X Receptors; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; PPAR gamma; RNA, Messenger; Scavenger Receptors, Class A