Page last updated: 2024-09-02

acetylleucyl-leucyl-norleucinal and geldanamycin

acetylleucyl-leucyl-norleucinal has been researched along with geldanamycin in 3 studies

Compound Research Comparison

Studies
(acetylleucyl-leucyl-norleucinal)
Trials
(acetylleucyl-leucyl-norleucinal)
Recent Studies (post-2010)
(acetylleucyl-leucyl-norleucinal)
Studies
(geldanamycin)
Trials
(geldanamycin)
Recent Studies (post-2010) (geldanamycin)
32105396059
3210531,1671329

Protein Interaction Comparison

ProteinTaxonomyacetylleucyl-leucyl-norleucinal (IC50)geldanamycin (IC50)
Lysine-specific demethylase 6BHomo sapiens (human)0.4
Lysine-specific demethylase 4BHomo sapiens (human)0.7
Tyrosine-protein kinase ABL1Homo sapiens (human)3
ATP-dependent molecular chaperone HSP82Saccharomyces cerevisiae S288C3.9667
Cytochrome P450 1A2Homo sapiens (human)0.014
Heat shock protein HSP 90-alphaHomo sapiens (human)0.0917
Heat shock protein HSP 90-betaHomo sapiens (human)0.098
Cytochrome P450 3A4Homo sapiens (human)0.014
Cytochrome P450 2D6Homo sapiens (human)0.014
Breakpoint cluster region proteinHomo sapiens (human)3
Heat shock protein HSP 90Oryctolagus cuniculus (rabbit)1.141
Cytochrome P450 2C9 Homo sapiens (human)0.074
Cytochrome P450 3A5Homo sapiens (human)0.014
Cytochrome P450 3A7Homo sapiens (human)0.014
Lysine-specific demethylase 5AHomo sapiens (human)0.13
Cytochrome P450 2C19Homo sapiens (human)0.074
EndoplasminCanis lupus familiaris (dog)0.01
Heat shock protein 75 kDa, mitochondrialHomo sapiens (human)0.661
Putative heat shock protein HSP 90-alpha A4Homo sapiens (human)0.14
Lysine-specific demethylase 4CHomo sapiens (human)0.7
Cytochrome P450 3A43 Homo sapiens (human)0.014

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
An, WG; Blagosklonny, MV; Neckers, L; Schulte, T; Sutphin, P; Whitesell, L1

Other Studies

3 other study(ies) available for acetylleucyl-leucyl-norleucinal and geldanamycin

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo.
    Oncogene, 1997, Jun-12, Volume: 14, Issue:23

    Topics: Acetylcysteine; Animals; Benzoquinones; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Detergents; Enzyme Inhibitors; Half-Life; Humans; Lactams, Macrocyclic; Leupeptins; Mice; Multienzyme Complexes; Mutation; Octoxynol; Polyethylene Glycols; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Quinones; Rats; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins

1997