Compounds > acetylleucyl-leucyl-norleucinal
Page last updated: 2024-09-02

acetylleucyl-leucyl-norleucinal and cyclosporine

acetylleucyl-leucyl-norleucinal has been researched along with cyclosporine in 4 studies

Compound Research Comparison

Studies
(acetylleucyl-leucyl-norleucinal)		Trials
(acetylleucyl-leucyl-norleucinal)		Recent Studies (post-2010)
(acetylleucyl-leucyl-norleucinal)		Studies
(cyclosporine)		Trials
(cyclosporine)		Recent Studies (post-2010) (cyclosporine)
32105319014
3210533772170
32105330,5473,8026,558

Protein Interaction Comparison

ProteinTaxonomyacetylleucyl-leucyl-norleucinal (IC50)cyclosporine (IC50)
ATP-binding cassette sub-family C member 3Homo sapiens (human)0.6315
Bile salt export pumpRattus norvegicus (Norway rat)0.6
Bile salt export pumpHomo sapiens (human)3.5
Interleukin-2Mus musculus (house mouse)0.005
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.6792
Cytochrome P450 3A4Homo sapiens (human)3.734
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 25.82
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)9.34
Cytochrome P450 3A5Homo sapiens (human)2.06
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.8
Substance-K receptorHomo sapiens (human)4.139
Peptidyl-prolyl cis-trans isomerase BHomo sapiens (human)0.0088
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)9.34
Cytochrome P450 3A7Homo sapiens (human)2.06
Cytochrome P450 2C19Homo sapiens (human)7
Multidrug resistance-associated protein 1 Homo sapiens (human)3.5082
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)9.34
Peptidyl-prolyl cis-trans isomerase A Homo sapiens (human)0.0252
Peptidyl-prolyl cis-trans isomerase FKBP4Homo sapiens (human)0.016
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.183
Peptidyl-prolyl cis-trans isomerase DHomo sapiens (human)0.0036
Sodium/bile acid cotransporterHomo sapiens (human)1
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.455
Cytochrome P450 3A43 Homo sapiens (human)2.06
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Mus musculus (house mouse)0.57
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.95

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Joly, A; Kohler, NG; Meyer, S1
Endo, H; Hamamoto, T; Inoki, Y; Kagawa, Y; Kajimoto, T; Kawase, M; Kawase, Y; Kinouchi, T; Miura, T; Tsuji, S; Yoshida, Y1

Other Studies

4 other study(ies) available for acetylleucyl-leucyl-norleucinal and cyclosporine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-kappaB activation.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Animals; Brain; Cattle; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Leupeptins; Lipopolysaccharides; Multienzyme Complexes; NF-kappa B; NF-kappa B p50 Subunit; Polyenes; Proteasome Endopeptidase Complex; Protein Precursors; Proto-Oncogene Proteins; Sirolimus; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha

1997
Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria.
    Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3

    Topics: Animals; Blotting, Western; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell-Free System; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Egtazic Acid; Gangliosides; Ion Channels; Leupeptins; Membrane Proteins; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Mimicry; Oligomycins; Rats

2000