Page last updated: 2024-09-02

acetylleucyl-leucyl-norleucinal and chloroquine

acetylleucyl-leucyl-norleucinal has been researched along with chloroquine in 6 studies

Compound Research Comparison

Studies
(acetylleucyl-leucyl-norleucinal)
Trials
(acetylleucyl-leucyl-norleucinal)
Recent Studies (post-2010)
(acetylleucyl-leucyl-norleucinal)
Studies
(chloroquine)
Trials
(chloroquine)
Recent Studies (post-2010) (chloroquine)
32105316,4057634,029

Protein Interaction Comparison

ProteinTaxonomyacetylleucyl-leucyl-norleucinal (IC50)chloroquine (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei43
Spike glycoproteinBetacoronavirus England 15.47
Replicase polyprotein 1abBetacoronavirus England 15.47
Transmembrane protease serine 2Homo sapiens (human)5.47
Dihydrofolate reductase Bos taurus (cattle)0.0301
Amyloid-beta precursor proteinHomo sapiens (human)7
Histidine-rich protein PFHRP-IIPlasmodium falciparum (malaria parasite P. falciparum)0.2383
Procathepsin LHomo sapiens (human)5.47
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.47
Replicase polyprotein 1abHuman coronavirus 229E5.47
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.47
Spike glycoproteinSevere acute respiratory syndrome coronavirus 23.58
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.375
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.5
Serine/threonine-protein kinase mTORHomo sapiens (human)0.27
Beta-secretase 1Homo sapiens (human)7
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.47
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.503
Angiotensin-converting enzyme 2 Homo sapiens (human)6.235
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.02
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.2

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bar-Nun, S; Inoue, S; Roitelman, J; Simoni, RD1
Getz, GS; Reardon, CA; Ye, SQ1
Beyer, EC; Green, K; Laing, JG; Saffitz, JE; Tadros, PN1
Chen, YT; Nelson, WJ; Stewart, DB1
Davis, RA; Du, EZ; Fleming, JF; Hui, TY; Olivier, L; Raabe, M; Spitsen, GM1
Ann, EJ; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH1

Other Studies

6 other study(ies) available for acetylleucyl-leucyl-norleucinal and chloroquine

ArticleYear
Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors.
    The Journal of biological chemistry, 1991, Jul-15, Volume: 266, Issue:20

    Topics: Animals; beta-Galactosidase; Calcium; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Egtazic Acid; Hydroxymethylglutaryl CoA Reductases; Kinetics; Leupeptins; Oligopeptides; Recombinant Fusion Proteins; Transfection

1991
Inhibition of apolipoprotein E degradation in a post-Golgi compartment by a cysteine protease inhibitor.
    The Journal of biological chemistry, 1993, Apr-25, Volume: 268, Issue:12

    Topics: Albumins; Ammonium Chloride; Animals; Apolipoproteins E; Brefeldin A; Calcium; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Golgi Apparatus; Humans; Kinetics; Leupeptins; Molecular Sequence Data; Transfection; Tumor Cells, Cultured

1993
Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.
    Cardiovascular research, 1998, Volume: 38, Issue:3

    Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats

1998
Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells.
    The Journal of cell biology, 1999, Feb-22, Volume: 144, Issue:4

    Topics: Amino Acid Sequence; Animals; Base Sequence; beta Catenin; Binding Sites; Cadherins; Cell Adhesion; Cell Line; Cell Membrane; Cell Polarity; Chloroquine; Cytoplasm; Cytoskeletal Proteins; Dogs; Endoplasmic Reticulum; Leupeptins; Macromolecular Substances; Molecular Sequence Data; Plasmids; Rats; Recombinant Fusion Proteins; Trans-Activators

1999
Chinese hamster ovary cells require the coexpression of microsomal triglyceride transfer protein and cholesterol 7alpha-hydroxylase for the assembly and secretion of apolipoprotein B-containing lipoproteins.
    The Journal of biological chemistry, 1999, Apr-02, Volume: 274, Issue:14

    Topics: Animals; Apolipoproteins B; Biological Transport; Carrier Proteins; Chloroquine; CHO Cells; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Dithiothreitol; Endoplasmic Reticulum; HeLa Cells; Humans; Leupeptins; Lipoproteins; Liver; Mice; Transfection

1999
Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
    Journal of cell science, 2012, Mar-01, Volume: 125, Issue:Pt 5

    Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination

2012