acetylleucyl-leucyl-norleucinal and carbobenzoxy-leucyl-leucyl-norvalinal

acetylleucyl-leucyl-norleucinal has been researched along with carbobenzoxy-leucyl-leucyl-norvalinal in 8 studies

Compound Research Comparison

Studies (acetylleucyl-leucyl-norleucinal)	Trials (acetylleucyl-leucyl-norleucinal)	Recent Studies (post-2010) (acetylleucyl-leucyl-norleucinal)	Studies (carbobenzoxy-leucyl-leucyl-norvalinal)	Trials (carbobenzoxy-leucyl-leucyl-norvalinal)	Recent Studies (post-2010) (carbobenzoxy-leucyl-leucyl-norvalinal)
321	0	53	84	0	16

Protein Interaction Comparison

Protein	Taxonomy	acetylleucyl-leucyl-norleucinal (IC50)	carbobenzoxy-leucyl-leucyl-norvalinal (IC50)
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus		3.14
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2		3.1401

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (50.00)	18.2507
2000's	3 (37.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (12.50)	2.80

Authors

Authors	Studies
Amin, SA; Banerjee, S; Gayen, S; Ghosh, K; Jha, T	1
Collins, T; Luscinskas, FW; Maniatis, T; Neish, AS; Palombella, VJ; Read, MA	1
Clark, K; Dick, L; Goldberg, AL; Gramm, C; Hwang, D; Rock, KL; Rothstein, L; Stein, R	1
Goldberg, AL; Maniatis, T; Palombella, VJ; Rando, OJ	1
Chan, L; Chen, SH; Yeung, SJ	1
Goldenberg, GJ; Lam, V; McPherson, JP; Salmena, L	1
Karlsen, AE; Sandler, S; Sternesjö, J	1
Hong, M; Lee, AS; Li, M; Mao, C	1

Reviews

1 review(s) available for acetylleucyl-leucyl-norleucinal and carbobenzoxy-leucyl-leucyl-norvalinal

Article	Year
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors. Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29 Topics: Antiviral Agents; Catalytic Domain; Coronavirus 3C Proteases; Cysteine Proteinase Inhibitors; Drug Discovery; Drug Evaluation, Preclinical; Molecular Docking Simulation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; SARS-CoV-2	2021

Article

Year

Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors.

Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

Topics: Antiviral Agents; Catalytic Domain; Coronavirus 3C Proteases; Cysteine Proteinase Inhibitors; Drug Discovery; Drug Evaluation, Preclinical; Molecular Docking Simulation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; SARS-CoV-2

2021

Other Studies

7 other study(ies) available for acetylleucyl-leucyl-norleucinal and carbobenzoxy-leucyl-leucyl-norvalinal

Article	Year
The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression. Immunity, 1995, Volume: 2, Issue:5 Topics: Base Sequence; Calpain; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cysteine Endopeptidases; E-Selectin; Endothelium, Vascular; Gene Expression; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-8; Leukocytes; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; Oligodeoxyribonucleotides; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; RNA, Messenger; Time Factors; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	1995
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell, 1994, Sep-09, Volume: 78, Issue:5 Topics: Amino Acid Sequence; Animals; Antigen Presentation; B-Lymphocytes; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Histocompatibility Antigens Class I; Leupeptins; Lymphocytes; Mice; Molecular Sequence Data; Multienzyme Complexes; Ovalbumin; Protease Inhibitors; Proteasome Endopeptidase Complex; T-Lymphocytes; Ubiquitins	1994
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell, 1994, Sep-09, Volume: 78, Issue:5 Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Cells, Cultured; Cysteine Endopeptidases; DNA-Binding Proteins; Humans; I-kappa B Proteins; Leupeptins; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Precursors; Protein Processing, Post-Translational; Ubiquitins	1994
Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B. Biochemistry, 1996, Oct-29, Volume: 35, Issue:43 Topics: Adenosine Triphosphate; Antibodies; Apolipoproteins B; Blotting, Western; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Leupeptins; Liver; Models, Biological; Multienzyme Complexes; Precipitin Tests; Protease Inhibitors; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Ubiquitins	1996
Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression. Biochemical pharmacology, 2001, Apr-01, Volume: 61, Issue:7 Topics: Acetylcysteine; Adenosine Triphosphate; Antigens, Neoplasm; Cell Cycle; Cell Extracts; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Topoisomerases, Type II; DNA-Binding Proteins; HeLa Cells; Humans; Isoenzymes; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured	2001
Involvement of the proteasome in IL-1beta induced suppression of islets of Langerhans in the rat. Upsala journal of medical sciences, 2003, Volume: 108, Issue:1 Topics: Animals; Base Sequence; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA; DNA Primers; Electrophoretic Mobility Shift Assay; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Leupeptins; Male; Multienzyme Complexes; Nitrites; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction	2003
Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6. Journal of cellular biochemistry, 2004, Jul-01, Volume: 92, Issue:4 Topics: Activating Transcription Factor 6; Animals; CHO Cells; Cricetinae; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Humans; Kidney; Leupeptins; Mice; Molecular Chaperones; NF-kappa B; NIH 3T3 Cells; Protease Inhibitors; Proteasome Endopeptidase Complex; Thapsigargin; Transcription Factors	2004