Page last updated: 2024-09-02

acetylleucyl-leucyl-norleucinal and beta-lapachone

acetylleucyl-leucyl-norleucinal has been researched along with beta-lapachone in 3 studies

Compound Research Comparison

Studies
(acetylleucyl-leucyl-norleucinal)
Trials
(acetylleucyl-leucyl-norleucinal)
Recent Studies (post-2010)
(acetylleucyl-leucyl-norleucinal)
Studies
(beta-lapachone)
Trials
(beta-lapachone)
Recent Studies (post-2010) (beta-lapachone)
3210534412255

Protein Interaction Comparison

ProteinTaxonomyacetylleucyl-leucyl-norleucinal (IC50)beta-lapachone (IC50)
Lysine-specific demethylase 4EHomo sapiens (human)3
Tyrosyl-DNA phosphodiesterase 2Homo sapiens (human)0.97
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.61
60 kDa heat shock protein, mitochondrialHomo sapiens (human)2.1
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)0.72
NADHomo sapiens (human)3.2
Protein kinase C alpha typeHomo sapiens (human)1.8
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)4
Protein-glutamine gamma-glutamyltransferase 2Homo sapiens (human)1.8
Caspase-1Homo sapiens (human)1.69
M-phase inducer phosphatase 1Homo sapiens (human)1.8
Tyrosine-protein kinase JAK3Homo sapiens (human)1.8
10 kDa heat shock protein, mitochondrialHomo sapiens (human)2.1
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)4
Transcription factor p65Homo sapiens (human)4
Receptor-type tyrosine-protein phosphatase etaHomo sapiens (human)1.8
Thiosulfate sulfurtransferaseHomo sapiens (human)0.12
Receptor protein-tyrosine kinase Homo sapiens (human)1.8
60 kDa chaperonin Escherichia coli0.945
10 kDa chaperonin Escherichia coli0.945
Mucosa-associated lymphoid tissue lymphoma translocation protein 1Homo sapiens (human)1.55

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Chau, GY; Chau, YP; Chien, CL; Don, MJ; Kung, HN; Lu, KS1

Other Studies

3 other study(ies) available for acetylleucyl-leucyl-norleucinal and beta-lapachone

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
Involvement of NO/cGMP signaling in the apoptotic and anti-angiogenic effects of beta-lapachone on endothelial cells in vitro.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Angiogenesis Inhibitors; Apoptosis; Arginine; Calcium; Calpain; Caspases; Cell Line; Cell Survival; Chelating Agents; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Leupeptins; Membrane Potential, Mitochondrial; Naphthoquinones; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oligopeptides; Signal Transduction; Time Factors

2007