Compounds > acetylgalactosamine
Page last updated: 2024-08-23

acetylgalactosamine and phosphoramidite

acetylgalactosamine has been researched along with phosphoramidite in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Brad Wan, W; Chappell, AE; Gaus, H; Kinberger, GA; Low, A; Migawa, MT; Prakash, TP; Seth, PP; Swayze, EE; Yu, J; Østergaard, ME1
Echeverria, D; Hassler, MR; Khvorova, A; Ly, S; Martynenko-Makaev, YV; Osborn, MF; Sharma, VK; Shmanai, VV; Ulashchik, EA; Watts, JK; Zatsepin, TS1
Harada-Shiba, M; Kashiwada, K; Obika, S; Terada, C; Yamamoto, T; Yamayoshi, A1
Akhlamionok, TP; Martynenko-Makaev, YV; Melnik, DM; Shmanai, VV; Ulashchik, EA; Zatsepin, TS1
Barry, JD; Berman, D; Brown, CR; Castoreno, A; Charissé, K; Egli, M; Harp, JM; Maier, MA; Manoharan, M; Matsuda, S; Schlegel, MK; Schofield, S; Szeto, J1

Other Studies

5 other study(ies) available for acetylgalactosamine and phosphoramidite

ArticleYear
Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Acetylgalactosamine; Animals; Dose-Response Relationship, Drug; Liver; Mice; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA, Messenger; Scavenger Receptors, Class B; Structure-Activity Relationship

2015
Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo.
    Bioconjugate chemistry, 2018, 07-18, Volume: 29, Issue:7

    Topics: Acetylgalactosamine; Animals; Cell Membrane; Cells, Cultured; Gene Silencing; Hepatocytes; Liver; Macromolecular Substances; Mice; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA, Small Interfering; Solid-Phase Synthesis Techniques

2018
Synthesis of Monovalent N-Acetylgalactosamine Phosphoramidite for Liver-Targeting Oligonucleotides.
    Current protocols in nucleic acid chemistry, 2019, Volume: 78, Issue:1

    Topics: Acetylgalactosamine; Drug Delivery Systems; Ligands; Liver; Oligonucleotides; Organophosphorus Compounds

2019
Synthesis of GalNAc-Oligonucleotide Conjugates Using GalNAc Phosphoramidite and Triple-GalNAc CPG Solid Support.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2282

    Topics: Acetylgalactosamine; Immobilized Nucleic Acids; Oligodeoxyribonucleotides; Organophosphorus Compounds; Research Design; RNA, Small Interfering; Workflow

2021
Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs.
    Nucleic acids research, 2021, 11-08, Volume: 49, Issue:19

    Topics: Acetylgalactosamine; Adenosine; Alcohol Oxidoreductases; Animals; Base Pairing; Chlorocebus aethiops; COS Cells; Cytidine; Dimethylformamide; Ethylamines; Female; Glycols; Guanosine; Hepatocytes; Hydrogen Bonding; Mice; Mice, Inbred C57BL; Oligoribonucleotides; Organophosphorus Compounds; Prealbumin; Primary Cell Culture; RNA Stability; RNA, Double-Stranded; RNA, Small Interfering

2021