acetylcysteine has been researched along with zidovudine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Clotet, B; Gomez, M; Romeu, J; Ruiz, L; Sirera, G | 1 |
| La Colla, P; Marongiu, ME; Pani, A | 1 |
| Agrawal, KC; Gogu, SR | 1 |
| Bauer, G; Chen, P; Factor, R; Markham, R; Mitchell, J; Schwartz, DH | 1 |
| Agrawal, KC; Ali, M; Mondal, D; Pradhan, L | 1 |
| Ahmad, IM; Aykin-Burns, N; Dayal, D; Dornfeld, KJ; Li, L; Mattson, DM; Orcutt, KP; Parsons, AD; Simons, AL; Spitz, DR | 1 |
| Banerjee, A; Banks, WA; Ercal, N; Manda, KR | 1 |
1 review(s) available for acetylcysteine and zidovudine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for acetylcysteine and zidovudine
| Article | Year |
|---|---|
Lack of short-term efficacy of N-acetyl-L-cysteine in human immunodeficiency virus-positive patients with CD4 cell counts < 250/mm3.
Topics: Acetylcysteine; Administration, Oral; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Seropositivity; Humans; Male; Zidovudine | 1995 |
16 other study(ies) available for acetylcysteine and zidovudine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Modulatory effect of N-acetyl-L-cysteine on the HIV-1 multiplication in chronically and acutely infected cell lines.
Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Division; Cell Fusion; Cell Line; Dextran Sulfate; HIV-1; Humans; Lymphoid Tissue; T-Lymphocytes; Virus Replication; Zidovudine | 1993 |
The protective role of zinc and N-acetylcysteine in modulating zidovudine induced hematopoietic toxicity.
Topics: Acetylcysteine; Animals; Antidotes; Bone Marrow; Cell Survival; Female; Hematopoietic Stem Cells; Mice; Zidovudine; Zinc | 1996 |
N-acetyl-cysteine and L-2-oxothiazolidine-4-carboxylic acid enhance contact-dependent growth of HIV in resting peripheral blood mononuclear cells (PBMC) in vitro and increase recovery of HIV from human-PBMC SCID mice.
Topics: Acetylcysteine; Animals; Anti-HIV Agents; CD2 Antigens; Cell Division; Cells, Cultured; Coculture Techniques; Down-Regulation; Female; HIV-1; Humans; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Male; Mice; Mice, SCID; Monocytes; Peritoneal Cavity; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Virus Replication; Zidovudine | 1997 |
Pot shots.
Topics: Acetylcysteine; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Antiviral Agents; Cattle; CD4 Lymphocyte Count; China; Clarithromycin; Clinical Trials as Topic; Clofazimine; Cryptosporidiosis; Drug Combinations; Ethambutol; Expectorants; Glutathione; Hepatitis B; Humans; Immunoglobulins; Interferon-alpha; Italy; Leprostatic Agents; Mycobacterium avium-intracellulare Infection; Philippines; Protease Inhibitors; Survival Rate; Taiwan; Thymosin; Zidovudine | 1996 |
HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants.
Topics: Acetylcysteine; Alkynes; Antioxidants; Antiretroviral Therapy, Highly Active; Benzoxazines; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cyclopropanes; Endothelial Cells; Endothelium, Vascular; Gene Expression; Glutathione; Humans; Indinavir; Interleukin-1; Leukocytes, Mononuclear; Nelfinavir; Oxazines; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Zidovudine | 2004 |
Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism.
Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Therapy, Combination; Glutathione; Head and Neck Neoplasms; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Sulfhydryl Compounds; Zidovudine | 2009 |
Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells.
Topics: Acetylcysteine; Adenosine Triphosphate; Antiretroviral Therapy, Highly Active; Apoptosis; Blood-Brain Barrier; Caspase 3; Cell Line, Transformed; Cytochromes c; Endothelial Cells; Glutathione; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Zidovudine | 2011 |