acetylcysteine and wortmannin

acetylcysteine has been researched along with wortmannin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.00)18.2507
2000's16 (53.33)29.6817
2010's11 (36.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
McMorris, FA; Vemuri, GS1
Greene, LA; Yan, CY1
Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y1
Fujiwara, H; Furukawa, K; Hagiya, S; Matsunaga, K; Nakamura, H; Ohizumi, Y; Saito, M1
Egan, BM; Greene, EL; Lu, G; Zhang, D1
Felts, N; Floyd, RA; Hensley, K; Pye, QN; Salsman, S1
Inanami, O; Kuwabara, M; Tsuji, M1
Cho, HJ; Chung, MH; Hyun, JW; Jeong, HG; Lee, JS; Woo, ER; You, HJ1
Bezombes, C; Demur, C; Filomenko, R; Hernandez, H; Jaffrézou, JP; Laurent, G; Maestre, N; Mas, VM; Plo, I; Quillet-Mary, A1
Castranova, V; Hur, KC; Kang, JL; Lee, HS; Pack, IS1
Hebert, C; Nikitakis, NG; Norris, K; Sauk, JJ; Siavash, H; Stewart, J1
Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G1
Douglas, P; Kurz, EU; Lees-Miller, SP1
Balla, A; Balla, T; Tsiomenko, A; Tuymetova, G; Várnai, P1
Capra, V; Citro, S; Ravasi, S; Rovati, GE; Viviani, B1
Inageda, K; Matsuoka, M; Nishitai, G; Suzuki, K1
Blomqvist, G; Dahl, A; Gudmundsson, A; Gustafsson, M; Lindbom, J; Ljungman, AG; Swietlicki, E1
Faurschou, A; Gniadecki, R1
Chen, L; Chen, W; Han, X; Huang, S; Kontos, CD; Liu, L; Luo, Y; Shen, T; Xu, B; Zhou, H1
Heo, JS; Lee, JC1
Itoh, Y; Iwai, M; Jo, M; Kagawa, K; Minami, M; Mitsuyoshi, H; Nakajima, T; Nishikawa, T; Okada, Y; Yamaguchi, K; Yasui, K; Yoshikawa, T1
Chen, HT; Chiang, YC; Hsu, HC; Huang, PH; Tang, CH; Tsai, CH1
Ishigaki, Y; Matsunaga, T; Nakagawa, H; Nogawa, A; Takegami, T; Zhao, X1
Hsu, PY; Yang, YW1
Huang, X; Li, D; Wu, M; Wu, Y; Zhu, M1
Chen, SC; Kao, SH; Liao, TL; Tzeng, CR1
Chan, WT; Chen, WX; He, Q; Hu, Q; Li, P; Shi, J; Wang, YY; Zhang, LJ1
Fang, SH; Fu, YJ; Gao, C; Li, J; Wang, P; Wang, W; Yao, LP; Zhang, J; Zhang, SD1
Andrulewicz-Botulinska, E; Hlebowicz-Sarat, K; Karna, E; Palka, JA; Szoka, L1

Other Studies

30 other study(ies) available for acetylcysteine and wortmannin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival.
    Development (Cambridge, England), 1996, Volume: 122, Issue:8

    Topics: Acetylcysteine; Androstadienes; Apoptosis; Ascorbic Acid; Blood; Cell Survival; Chromones; Ciliary Neurotrophic Factor; Enzyme Inhibitors; Fibroblast Growth Factor 2; Insulin-Like Growth Factor I; Morpholines; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Oligodendroglia; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Signal Transduction; Stem Cells; Vitamin E; Wortmannin

1996
Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jun-01, Volume: 18, Issue:11

    Topics: Acetylcysteine; Androstadienes; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Survival; Chromones; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression Regulation; Genes, Immediate-Early; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neurons; Nitric Oxide Synthase; PC12 Cells; ras Proteins; Rats; Signal Transduction; Wortmannin

1998
Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:6

    Topics: Acetylcysteine; Androstadienes; Cell Differentiation; Chelating Agents; Cysteine; Dithiothreitol; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Sulfhydryl Reagents; Tyrosine; Unithiol; Wortmannin

1998
Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells.
    European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1

    Topics: Acetylcysteine; Androstadienes; Animals; Apoptosis; Blotting, Western; Cell Size; Cell Survival; DNA Fragmentation; Flow Cytometry; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Nerve Growth Factor; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Porifera; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinones; Rats; Wortmannin

2001
Signaling events mediating the additive effects of oleic acid and angiotensin II on vascular smooth muscle cell migration.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2

    Topics: Acetylcysteine; Analysis of Variance; Androstadienes; Angiotensin II; Animals; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oleic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Signal Transduction; Wortmannin

2001
Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.
    Archives of biochemistry and biophysics, 2001, Feb-15, Volume: 386, Issue:2

    Topics: Acetylcysteine; Androstadienes; Animals; Antimycin A; Astrocytes; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Hydrogen Peroxide; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rotenone; Signal Transduction; Tumor Suppressor Proteins; Uncoupling Agents; Wortmannin

2001
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
    The Journal of biological chemistry, 2001, Aug-31, Volume: 276, Issue:35

    Topics: Acetylcysteine; Androstadienes; Animals; Cyclic N-Oxides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Indoles; Isoquinolines; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurites; Neuroprotective Agents; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Kinase C; ras Proteins; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Wortmannin

2001
Oncogenic H-Ras enhances DNA repair through the Ras/phosphatidylinositol 3-kinase/Rac1 pathway in NIH3T3 cells. Evidence for association with reactive oxygen species.
    The Journal of biological chemistry, 2002, May-31, Volume: 277, Issue:22

    Topics: 3T3 Cells; Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Line; Cell Survival; Chromones; Cisplatin; DNA; DNA Repair; Enzyme Inhibitors; Genes, ras; Luciferases; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Plasmids; rac1 GTP-Binding Protein; ras Proteins; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection; Ultraviolet Rays; Wortmannin

2002
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin.
    Blood, 2003, Feb-15, Volume: 101, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antioxidants; Bridged-Ring Compounds; Cell Death; Daunorubicin; Diglycerides; Enzyme Activation; Flavonoids; Humans; Leukemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Thiocarbamates; Thiones; Transfection; Tumor Cells, Cultured; Wortmannin

2003
Phosphoinositide 3-kinase activity leads to silica-induced NF-kappaB activation through interacting with tyrosine-phosphorylated I(kappa)B-alpha and contributing to tyrosine phosphorylation of p65 NF-kappaB.
    Molecular and cellular biochemistry, 2003, Volume: 248, Issue:1-2

    Topics: Acetylcysteine; Androstadienes; Animals; Antioxidants; Blotting, Western; Cell Line; Cell Nucleus; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Lipopolysaccharides; Mice; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Pyrrolidines; Reactive Oxygen Species; Silicon Dioxide; Superoxide Dismutase; Thiocarbamates; Time Factors; Tyrosine; Wortmannin

2003
Phenotypic switching of VEGF and collagen XVIII during hypoxia in head and neck squamous carcinoma cells.
    Oral oncology, 2003, Volume: 39, Issue:8

    Topics: Acetylcysteine; Androstadienes; Antimutagenic Agents; Biomarkers; Cell Hypoxia; Cell Line, Tumor; Cobalt; Collagen Type XVIII; Enzyme Inhibitors; Head and Neck Neoplasms; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Humans; Imidazoles; MAP Kinase Signaling System; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Vascular Endothelial Growth Factor A; Wortmannin

2003
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
    American journal of respiratory cell and molecular biology, 2004, Volume: 31, Issue:5

    Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin

2004
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2004
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.
    Molecular biology of the cell, 2005, Volume: 16, Issue:3

    Topics: 1-Phosphatidylinositol 4-Kinase; Acetylcysteine; Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Blotting, Western; Calcium; Carrier Proteins; Cell Membrane; Chelating Agents; Chlorocebus aethiops; COS Cells; Cytoplasm; DNA; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Golgi Apparatus; Green Fluorescent Proteins; Humans; Immunohistochemistry; Ionomycin; Ionophores; Lipid Metabolism; Microscopy, Confocal; Phosphatidylinositol Phosphates; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Steroid; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection; Wortmannin

2005
CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation.
    Respiratory research, 2006, Mar-22, Volume: 7

    Topics: Acetylcysteine; Androstadienes; Bronchi; Cell Proliferation; Cells, Cultured; Chromones; DNA; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Humans; Leukotriene D4; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Myocytes, Smooth Muscle; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; ras Proteins; Reactive Oxygen Species; Receptors, Leukotriene; Transcriptional Activation; Wortmannin

2006
Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: involvement of ATM pathway.
    Toxicology and applied pharmacology, 2007, Apr-01, Volume: 220, Issue:1

    Topics: Acetylcysteine; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Butadienes; Catalase; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; DNA-Binding Proteins; Epithelial Cells; Humans; Lung; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vanadates; Wortmannin

2007
Wear particles generated from studded tires and pavement induces inflammatory reactions in mouse macrophage cells.
    Chemical research in toxicology, 2007, Volume: 20, Issue:6

    Topics: Acetylcysteine; Androstadienes; Animals; Cell Line; Cell Survival; Cytokines; Deferoxamine; Free Radical Scavengers; Gene Expression; Inflammation; Interleukin-6; Lipid Peroxidation; Macrophages; Mice; Microscopy, Electron, Scanning; Motor Vehicles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Particulate Matter; Quartz; Reactive Oxygen Species; RNA, Messenger; Silicon Dioxide; Tumor Necrosis Factor-alpha; Wortmannin

2007
TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes.
    Experimental dermatology, 2008, Volume: 17, Issue:12

    Topics: Acetylcysteine; Androstadienes; Apoptosis; Blotting, Western; Caspases; Cell Line; Cell Survival; Chromones; Deferoxamine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Keratinocytes; Leupeptins; Morpholines; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tocopherols; Tumor Necrosis Factor-alpha; Wortmannin

2008
Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death.
    Free radical biology & medicine, 2011, Mar-01, Volume: 50, Issue:5

    Topics: Acetylcysteine; Androstadienes; Animals; Apoptosis; Cadmium; Carrier Proteins; Environmental Pollutants; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; NADPH Oxidases; Neurodegenerative Diseases; Neurons; PC12 Cells; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Receptors, Somatomedin; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Wortmannin

2011
β-Catenin mediates cyclic strain-stimulated cardiomyogenesis in mouse embryonic stem cells through ROS-dependent and integrin-mediated PI3K/Akt pathways.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:7

    Topics: Acetylcysteine; Androstadienes; Animals; Antioxidants; Ascorbic Acid; beta Catenin; Cell Culture Techniques; Cell Differentiation; Cell Line; Connexin 43; Embryoid Bodies; Embryonic Stem Cells; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Integrin alpha5beta1; Mice; Myocytes, Cardiac; Periodicity; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Stress, Mechanical; Transcription Factors; Wortmannin

2011
Oxidative stress is closely associated with tumor angiogenesis of hepatocellular carcinoma.
    Journal of gastroenterology, 2011, Volume: 46, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Androstadienes; Antioxidants; Carcinoma, Hepatocellular; Cell Proliferation; Endothelial Cells; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neovascularization, Pathologic; Oxidative Stress; Proto-Oncogene Proteins c-akt; RNA, Messenger; Umbilical Cord; Vascular Endothelial Growth Factor A; Wortmannin

2011
High glucose induces vascular endothelial growth factor production in human synovial fibroblasts through reactive oxygen species generation.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:3

    Topics: Acetylcysteine; Androstadienes; Chromones; Curcumin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Glucose; Humans; Joint Capsule; Morpholines; NADPH Oxidases; Osteoarthritis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1; Vascular Endothelial Growth Factor A; Wortmannin

2013
Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.
    International journal of oncology, 2014, Volume: 44, Issue:1

    Topics: Acetylcysteine; Androstadienes; Cycloheximide; Exons; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Nonsense Mediated mRNA Decay; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteasome Inhibitors; Protein Serine-Threonine Kinases; RNA Helicases; RNA-Binding Proteins; RNA, Small Interfering; Trans-Activators; Transcription Factors; Ubiquitin; Wortmannin

2014
Gene delivery via the hybrid vector of recombinant adeno-associated virus and polyethylenimine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: Acetylcysteine; Androstadienes; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cytochalasin B; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyethyleneimine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Vitamin E; Wortmannin

2014
TREM-2 promotes macrophage-mediated eradication of Pseudomonas aeruginosa via a PI3K/Akt pathway.
    Scandinavian journal of immunology, 2014, Volume: 79, Issue:3

    Topics: Acetylcysteine; Androstadienes; Animals; Bacterial Load; Cell Line; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Macrophages; Membrane Glycoproteins; Mice; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pseudomonas aeruginosa; Pseudomonas Infections; Reactive Oxygen Species; Receptors, Immunologic; RNA Interference; RNA, Small Interfering; Signal Transduction; Wortmannin

2014
TCDD induces the hypoxia-inducible factor (HIF)-1α regulatory pathway in human trophoblastic JAR cells.
    International journal of molecular sciences, 2014, Sep-30, Volume: 15, Issue:10

    Topics: Acetylcysteine; Androstadienes; Cell Line; Cell Movement; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Matrix Metalloproteinase 9; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Polychlorinated Dibenzodioxins; PPAR gamma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Vascular Endothelial Growth Factor A; Wortmannin

2014
Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cells.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Acetylcysteine; Analysis of Variance; Androstadienes; Apoptosis Regulatory Proteins; Autophagy; Bacterial Proteins; Beclin-1; Blotting, Western; Cell Line; DNA Primers; Epithelial Cells; Humans; Membrane Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mutation; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Polymerase Chain Reaction; Pulmonary Alveoli; Reactive Oxygen Species; Signal Transduction; Streptococcus pneumoniae; Streptolysins; TOR Serine-Threonine Kinases; Wortmannin

2015
Juglone induces apoptosis and autophagy via modulation of mitogen-activated protein kinase pathways in human hepatocellular carcinoma cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 116, Issue:Pt B

    Topics: Acetylcysteine; Adenine; Amino Acid Chloromethyl Ketones; Androstadienes; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Enzyme Activation; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Wortmannin

2018
The mechanism for differential effect of nelfinavir and indinavir on collagen metabolism in human skin fibroblasts.
    Experimental dermatology, 2019, Volume: 28, Issue:7

    Topics: Acetylcysteine; Ascorbic Acid; Cell Survival; Collagen; Dipeptidases; DNA; Down-Regulation; Fibroblasts; Glutamine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; NF-kappa B p50 Subunit; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Skin; Wortmannin

2019