acetylcysteine and vancomycin

acetylcysteine has been researched along with vancomycin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's10 (55.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, F; Chen, W; Hu, L; Lan, L; Li, B; Li, J; Li, X; Lin, D; Liu, W; Liu, Y; Lu, Y; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Xu, Y; Zheng, X; Zhu, J1
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J1
Chen, F; Hu, L; Lan, L; Li, B; Li, J; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Zheng, X; Zhu, J1
Abouelhassan, Y; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Kim, YS; Luesch, H; Tan, H1
Brumfitt, W; Hamilton-Miller, JM; Maple, PA1
Cheng, N; Chow, AW1
Pohlod, DJ; Saravolatz, LD; Somerville, MM1
Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV1
Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S1
Kocyigit, I; Oymak, O; Sipahioglu, M; Somdas, M; Tokgoz, B; Ucar, C; Unal, A; Utas, C; Vural, A1
Inokoshi, J; Koyama, N; Tomoda, H1
Badri, S; Khorvash, F; Meidani, M; Sayadi, M; Soltani, R; Taheri, S1

Reviews

2 review(s) available for acetylcysteine and vancomycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Anti-infectious agents against MRSA.
    Molecules (Basel, Switzerland), 2012, Dec-24, Volume: 18, Issue:1

    Topics: Acetylcysteine; Alkyl and Aryl Transferases; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Cell Wall; Diterpenes; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycotoxins; Organothiophosphorus Compounds; Peptidoglycan; Spiro Compounds; Teichoic Acids; Vancomycin; Virulence Factors; Xanthophylls

2012

Trials

2 trial(s) available for acetylcysteine and vancomycin

ArticleYear
Protective effect of N-acetylcysteine from drug-induced ototoxicity in uraemic patients with CAPD peritonitis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:12

    Topics: Acetylcysteine; Amikacin; Anti-Bacterial Agents; Ear Diseases; Free Radical Scavengers; Humans; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Prospective Studies; Vancomycin

2011
Effect of N-acetylcysteine against Vancomycin-Induced Nephrotoxicity: A Randomized Controlled Clinical Trial.
    Archives of Iranian medicine, 2020, 06-01, Volume: 23, Issue:6

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Antioxidants; Blood Urea Nitrogen; Creatinine; Female; Humans; Male; Middle Aged; Reactive Oxygen Species; Vancomycin

2020

Other Studies

14 other study(ies) available for acetylcysteine and vancomycin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Drug Resistance, Bacterial; Ether-A-Go-Go Potassium Channels; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship; Vancomycin; Vancomycin Resistance; Xanthophylls

2017
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
    Journal of medicinal chemistry, 2018, 01-11, Volume: 61, Issue:1

    Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water

2018
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.
    European journal of medicinal chemistry, 2018, Feb-10, Volume: 145

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin; Mice; Microbial Sensitivity Tests; Molecular Structure; Oxidoreductases; Piperonyl Butoxide; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin

2018
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Halogenation; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenazines

2018
Comparative in-vitro activity of vancomycin, teicoplanin, ramoplanin (formerly A16686), paldimycin, DuP 721 and DuP 105 against methicillin and gentamicin resistant Staphylococcus aureus.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23, Issue:4

    Topics: Acetylcysteine; Anti-Bacterial Agents; Culture Media; Depsipeptides; Disaccharides; Drug Resistance, Microbial; Gentamicins; Glycopeptides; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillin Resistance; Peptides, Cyclic; Staphylococcus aureus; Teicoplanin; Temperature; Vancomycin

1989
In vitro activities of daptomycin (LY146032) and paldimycin (U-70,138F) against anaerobic gram-positive bacteria.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bacteria, Anaerobic; Culture Media; Daptomycin; Disaccharides; Glycopeptides; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Penicillin G; Peptides; Vancomycin

1988
In vitro susceptibility of gram-positive cocci to paldimycin.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Acetylcysteine; Anti-Bacterial Agents; Culture Media; Disaccharides; Enterococcus faecalis; Glycopeptides; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Temperature; Vancomycin

1987
In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4

    Topics: Acetylcysteine; Bacterial Infections; Disaccharides; Glycopeptides; Gram-Positive Bacteria; Neoplasms; Vancomycin

1987
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply

2007