acetylcysteine and u 0126

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins

Topics: Acetylcysteine; Active Transport, Cell Nucleus; Breast Neoplasms; Butadienes; Cell Nucleus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Epidermal Growth Factor; Fatty Acids, Unsaturated; Humans; Ligands; Mitogen-Activated Protein Kinase Kinases; Multienzyme Complexes; Mutation; Nitriles; Phosphorylation; Promegestone; Proteasome Endopeptidase Complex; Receptors, Progesterone; Serine; Transcription, Genetic; Tumor Cells, Cultured

Topics: Acetaldehyde; Acetylcysteine; Animals; Anthracenes; Apoptosis; Blotting, Western; Butadienes; Buthionine Sulfoximine; Caspase 3; Caspases; Cell Nucleus; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Hepatocytes; Hydrogen Peroxide; Indoles; JNK Mitogen-Activated Protein Kinases; Male; Maleates; Maleimides; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors

Topics: Acetylcysteine; Anthracenes; Antioxidants; Apoptosis; Ascorbic Acid; Butadienes; Cell Line, Tumor; Cell Proliferation; DNA Damage; Enzyme Inhibitors; Fluoresceins; HeLa Cells; Humans; Imidazoles; MAP Kinase Signaling System; Melatonin; Mitochondria; Nitriles; Nitrites; Oxazines; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Radiation Tolerance; Rhodamines; Spectrometry, Fluorescence; Xanthenes

Topics: Acetylcysteine; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Butadienes; Catalase; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; DNA-Binding Proteins; Epithelial Cells; Humans; Lung; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vanadates; Wortmannin

Topics: Acetylcysteine; Activating Transcription Factor 2; Animals; Antioxidants; Brain; Butadienes; Buthionine Sulfoximine; Glutathione; Imidazoles; Kidney; Liver; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Nitriles; Oxidative Stress; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; Sulfhydryl Compounds

Topics: Acetophenones; Acetylcysteine; Butadienes; Cells, Cultured; Curcumin; Cytoplasm; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Kinase Kinases; Myocytes, Smooth Muscle; NADPH Oxidases; NF-kappa B; Nitriles; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; RNA, Small Interfering; Sesquiterpenes; Sesquiterpenes, Guaiane; Smoking; Trachea; Transcription Factor AP-1; Transcriptional Activation

Topics: Acetylcysteine; Animals; Blotting, Western; Butadienes; Catalase; Cell Line; Fluorescent Antibody Technique; Glutathione; HEK293 Cells; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Hydrogen Peroxide; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Kaposi; Signal Transduction; Virus Activation; Virus Latency; Virus Replication

Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Butadienes; Calpain; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Cytoprotection; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Gestational Age; In Situ Nick-End Labeling; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Neuroprotective Agents; Nitriles; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Signal Transduction; Spectrin; Time Factors

Topics: Acetylcysteine; Actins; Animals; Biomarkers; Butadienes; Cadherins; Cell Line; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; MAP Kinase Signaling System; Nitriles; Pulmonary Alveoli; Radiation Pneumonitis; Radiation, Ionizing; Radiotherapy; Rats; Respiratory Mucosa; Snail Family Transcription Factors; Transcription Factors

Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Butadienes; Caspases; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Disulfides; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Imidazoles; MAP Kinase Signaling System; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfinic Acids

Topics: Acetylcysteine; Antioxidants; ATP-Binding Cassette Transporters; Butadienes; Cell Line, Tumor; DNA-Binding Proteins; Humans; Hydrogen Peroxide; Imidazoles; Janus Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein D; Pyridines; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Transcription Factors; Tyrphostins

Topics: Acetylcysteine; Animals; Anthracenes; Aorta; Butadienes; Cell Movement; Cell Proliferation; Cells, Cultured; Chromones; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Imidazoles; Inula; Male; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Nitriles; Platelet-Derived Growth Factor; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sesquiterpenes

Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Butadienes; Cadmium; Cell Line; Extracellular Signal-Regulated MAP Kinases; Glutathione Peroxidase; Imidazoles; JNK Mitogen-Activated Protein Kinases; Malondialdehyde; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

Topics: Acetylcysteine; Butadienes; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Maleimides; MAP Kinase Kinase Kinases; Mitochondria; Nitric Oxide Synthase Type III; Nitriles; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; rho-Associated Kinases; Threonine

Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Butadienes; Cell Line; Cell Survival; Enzyme Inhibitors; Flavanones; Fruit; Glucose; Hyperglycemia; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Pyridines; Rats; Reactive Oxygen Species

Topics: Acetylcysteine; Butadienes; Docosahexaenoic Acids; Down-Regulation; Heme Oxygenase-1; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-E2-Related Factor 2; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Response Elements; U937 Cells; Up-Regulation

Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Butadienes; Caspase 3; Cell Survival; Cochlea; Gene Expression Regulation; Gentamicins; Hair Cells, Auditory; Humans; Mice; Mitochondria; Nitriles; Organ of Corti; Protein Serine-Threonine Kinases; Reactive Oxygen Species