acetylcysteine has been researched along with tyrosine in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.33) | 18.7374 |
| 1990's | 11 (12.22) | 18.2507 |
| 2000's | 48 (53.33) | 29.6817 |
| 2010's | 26 (28.89) | 24.3611 |
| 2020's | 2 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Salemnick, G; Stöhrer, G | 1 |
| Glatt, H | 1 |
| Ekman, L; Magnusson, I; Wahren, J; Wångdahl, M | 1 |
| Bässler, B; Neuhäuser, M; Welsch, B | 1 |
| Earp, HS; Huckle, WR | 1 |
| Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC; Sun, SC | 1 |
| Bartsch, H; Friesen, MD; Lin, D; Ohshima, H; Prevost, V; Shuker, DE | 1 |
| Bärtsch, P; Dröge, W; Edler, L; Fischbach, T; Friedmann, B; Hack, V; Kinscherf, R; Weiss, C | 1 |
| Kanterewicz, BI; Klann, E; Knapp, LT | 1 |
| Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y | 1 |
| Fang, CH; Fischer, JE; Hasselgren, PO; Hobler, S; Li, BG; Wang, JJ | 1 |
| Chrétien, S; Gisselbrecht, S; Lacombe, C; Mayeux, P; Muller, O; Varlet, P; Verdier, F; Yoshimura, A | 1 |
| Bloom, ET; Furuke, K | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S | 1 |
| Gon, Y; Hashimoto, S; Horie, T; Jibiki, I; Kudoh, S; Matsumoto, K; Takeshita, I; Takizawa, H | 1 |
| Carpino, N; Feng, J; Ihle, JN; Marine, JC; Moriggl, R; Stravopodis, D; Teglund, S; Wang, D | 1 |
| Abas, L; Bogoyevitch, MA; Court, NW; Dhillon, A; Draper, KA; Ng, DC | 1 |
| Calabrò, G; Caputi, AP; Costantino, G; Cucinotta, G; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E; Serraino, I | 1 |
| Gamero, AM; Larner, AC | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Gieche, J; Grune, T; Klotz, LO; Rudeck, M; Sies, H | 1 |
| Halliwell, B; Hyun, DH; Jenner, P; Lee, MH | 1 |
| Haruta, T; Iwata, M; Kawahara, J; Kobayashi, M; Takano, A; Uno, T; Usui, I | 1 |
| Besner, JG; Bouchard, JF; Cabassi, A; de Champlain, J; Dumont, EC; Girouard, H; Lamontagne, D; Le Jossec, M | 1 |
| Britti, D; Caputi, AP; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
| Huh, KW; Siddiqui, A; Waris, G | 1 |
| Bloch, KD; Ichinose, F; Orbach, P; Raveh, Y; Zapol, WM | 1 |
| Granner, DK; Hall, RK; Law, BK; Nawano, M; Waltner-Law, ME; Wang, XL | 1 |
| Kato, M; Mantani, T; Toyo'oka, T | 1 |
| Chang, CH; Chang, GD; Che, D; Chen, ZJ; Liu, S; Vetter, M | 1 |
| Chang, YH; Chen, CW; Lin, WW; Tsi, CJ | 1 |
| Castranova, V; Hur, KC; Kang, JL; Lee, HS; Pack, IS | 1 |
| Hinson, JA; James, LP; Mayeux, PR | 1 |
| Hasegawa, K; Inoue, S; Ito, S; Olivares, C; Otake, H; Solano, F; Wakamatsu, K; Yukitake, J | 1 |
| Becker, D; Bruchhausen, S; Knop, J; Valk, E; Zahn, S | 1 |
| Desaki, M; Kawasaki, S; Kohyama, T; Okazaki, H; Takizawa, H; Yamamoto, K; Yamauchi, Y | 1 |
| Andersen, CI; Bennett, RG; Berhanu, P; Duckworth, WC; Fawcett, J; Hamel, FG | 1 |
| Rey, O; Rozengurt, E; Waldron, RT; Zhukova, E | 1 |
| Cinel, I; Cinel, L; Ercan, B; Kanik, A; Koksel, O; Oral, U; Ozdulger, A; Tamer, L | 1 |
| Ahokas, RA; Bhattacharya, SK; Gerling, IC; Sun, Y; Weber, KT | 1 |
| Loo, JA; Nel, AE; Xiao, GG | 1 |
| Descamps-Latscha, B; Drüeke, TB; Ivanovski, O; Lacour, B; Massy, ZA; Nguyen-Khoa, T; Phan, O; Ruellan, N; Szumilak, D | 1 |
| Cheng, X; Leo, JM; Pang, CC; Xia, Z | 1 |
| Halliwell, B; Hyun, DH; Jenner, P; Lee, M | 1 |
| Alvarez, FJ; Barreiro, E; Gáldiz, JB; Gea, J; Hussain, SN; Mariñán, M | 1 |
| Atlas, D; Bartov, O; Butterfield, DA; Sultana, R | 1 |
| Cook, CC; Hinson, JA; Light, KE; Pierce, DR | 1 |
| Chen, YS; Hsu, MF; Huang, LJ; Kuo, SC; Tsao, LT; Wang, JP | 1 |
| Ippolito, S; Mani, AR; Moore, KP; Ollosson, R | 1 |
| Bosari, S; Carelli, S; Di Giulio, AM; Gorio, A; Paratore, S | 1 |
| MacLeod, KM; McNeill, JH; Nagareddy, PR; Xia, Z | 1 |
| Alvarez-Barrientos, A; Fernández, AP; Lamas, S; León-Gómez, E; Navarro-Antolín, J; Redondo-Horcajo, M; Rodrigo, J; Zaragoza, C | 1 |
| Biswas, SK; de Faria, JB | 1 |
| Celedón, G; González, G; Lissi, EA; Pino, J | 1 |
| Deng, L; Frank, SJ; Fuchs, SY; He, K; Jiang, J; Thangavel, C; Wang, X; Yang, N | 1 |
| Aburatani, H; Fukayama, M; Goto, A; Ishikawa, S; Matsubara, D; Miyazawa, K; Nakamura, Y; Niki, T; Ota, S; Sachiko, O | 1 |
| Burke, AS; Hinson, JA; James, LP; Kurten, RC; Redeker, K | 1 |
| Bigam, DL; Cheung, PY; Lee, TF; Tymafichuk, CN | 1 |
| Hou, MC; Huang, YT; Lee, FY; Lee, KC; Lee, SD; Lin, HC; Wang, YW; Yang, YY | 1 |
| Güler, G; Karasu, C; Ozgur, E; Seyhan, N; Tomruk, A; Türközer, Z | 1 |
| Anantharam, V; Bravosanpedro, JM; Fuentes, JM; González-Polo, RA; Kanthasamy, AG; Morán, JM; Niso-Santano, M; Ortiz-Ortiz, MA; Soler, G | 1 |
| Abdelsaid, MA; Al-Shabrawey, M; El-Remessy, AB; Matragoon, S; Pillai, BA; Prakash, R | 1 |
| Colles, SM; Graham, LM; Miyazaki, K; Rosenbaum, MA | 1 |
| Goldammer, T; Krüger, B; Löhrke, B; Viergutz, T; Weitzel, JM; Xu, J | 1 |
| Ahmed, M; Girnun, GD; Goldberg, SN; Levchenko, T; Rahmanuddin, S; Schor-Bardach, R; Signoretti, S; Solazzo, SA; Spitz, DR; Torchilin, V; Yang, W | 1 |
| Bradley, EA; Dywer, RM; McConell, GK; Merry, TL; Rattigan, S | 1 |
| Unger, EC | 1 |
| Ahn, JY; Bennett, JP; Onyango, IG; Swerdlow, RH; Tuttle, JB | 1 |
| Ali, SF; Bains, M; Clark, RA; Imam, SZ; Kahle, PJ; Li, S; Roberts, JL; Valente, AJ; Yamamoto, A; Zhou, Q | 1 |
| Ahmad, A; Aloisi, C; Catania, MA; Cuzzocrea, S; Di Paola, R; Esposito, E; Italiano, D; Mazzon, E; Mondello, P; Mondello, S | 1 |
| Evans, LC; Liu, H; Pinkas, GA; Thompson, LP | 1 |
| Akgul, Y; Cheong, N; Dannevig, I; Liao, J; Longoria, C; Mahendroo, M; Mija, DS; Nakstad, B; Ramgopal, M; Saugstad, OD; Savani, RC; Wyckoff, MH; Østerholt, HC | 1 |
| Accili, D; Ferrante, AW; Murphy, AJ; Subramanian, V; Tall, AR; Tsuchiya, K; Westerterp, M | 1 |
| Haidari, M; Wakame, K; Zhang, W | 1 |
| Goldstein, GA; Pandya, JD; Patel, SP; Pauly, JR; Rabchevsky, AG; Readnower, RD; Sullivan, PG; Yonutas, HM | 1 |
| Bonnaure, G; Néron, S | 1 |
| Andrade, CF; da Rosa, DP; Forgiarini, LA; Forgiarini, LF; Mariano, R; Paludo, Ade O; Silva, MB | 1 |
| Aguirre, A; Díaz, MI; Leyton, L; Llanos, P; Mc Master, C; Ortiz, R; Quest, AF; Valenzuela, M; Wehinger, S | 1 |
| Bonomo, C; Cezar, MD; Damatto, RL; Fernandes, DC; Guizoni, DM; Junior, SA; Laurindo, FR; Lima, AR; Martinez, PF; Matsubara, LS; Novelli, EL; Okoshi, K; Okoshi, MP; Pagan, LU; Seiva, FR; Zornoff, LA | 1 |
| Čalkovská, A; Kolomazník, M; Kopincová, J; Mikolka, P; Mokrá, D | 1 |
| Chen, J; Hill, K; Lemasters, J; Sha, SH; Wang, X; Yang, SM; Yuan, H | 1 |
| Amboni, RT; Arent, CO; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS | 1 |
| Colares, JR; da Silva, J; Fisher, C; Hartmann, RM; Licks, F; Marques, C; Marroni, NP; Reys, J; Schemitt, E; Soares, Mdo C | 1 |
| Gao, F; He, Z; Hu, Y; Ma, S; Xiao, X; Zhao, D | 1 |
| Carvalho-Silva, M; De Prá, SD; Ferreira, GC; Gomes, LM; Rebelo, J; Scaini, G; Schuck, PF; Streck, EL; Teixeira, LJ; Teodorak, BP; Zeni, N | 1 |
| Chan, PC; Chen, YL; Hsieh, PS; Hsu, WN; Tian, YF; Wang, YC | 1 |
| Bogo, MR; Carvalho-Silva, M; de Moura, AB; Deroza, PFP; Ferreira, GC; Gomes, LM; Gomes, ML; Kist, LW; Malgarin, F; Quevedo, J; Réus, GZ; Rico, EP; Scaini, G; Schuck, PF; Streck, EL; Zugno, AI | 1 |
| Chen, XY; Ha, W; Jin, XJ; Shi, YP | 1 |
| Jensen, RT; Moody, TW; Ramos-Alvarez, I | 1 |
2 review(s) available for acetylcysteine and tyrosine
| Article | Year |
|---|---|
Urinary markers for measuring exposure to endogenous and exogenous alkylating agents and precursors.
Topics: Acetylcysteine; Adenine; Alkylating Agents; Animals; Biomarkers; DNA Damage; Environmental Monitoring; Humans; Tyrosine | 1993 |
Acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Chemical and Drug Induced Liver Injury; Cytokines; Humans; Kupffer Cells; Liver Diseases; Mitochondria, Liver; Oxidative Stress; Tyrosine | 2003 |
2 trial(s) available for acetylcysteine and tyrosine
| Article | Year |
|---|---|
Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals: the effect of N-acetyl-cysteine.
Topics: Acetylcysteine; Adult; Aerobiosis; Anaerobiosis; Body Weight; Cachexia; Cystine; Exercise; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Tyrosine | 1996 |
N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI.
Topics: Acetylcysteine; Aldehydes; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Double-Blind Method; Energy Metabolism; Glutathione; Male; Maze Learning; Mitochondria; Neuroprotective Agents; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2014 |
86 other study(ies) available for acetylcysteine and tyrosine
| Article | Year |
|---|---|
Oxidizing action of purine N-oxide esters.
Topics: Acetylation; Acetylcysteine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic N-Oxides; Cysteine; Esters; Guanine; Hydrogen-Ion Concentration; Iodides; Iodine; Mercaptopurine; Methionine; Oxidation-Reduction; Purines; Pyridines; Sulfates; Sulfhydryl Compounds; Tryptophan; Tyrosine; Uric Acid; Xanthines | 1975 |
Endogenous mutagens derived from amino acids.
Topics: Acetylcysteine; Amino Acids; Animals; Cells, Cultured; Homogentisic Acid; Levodopa; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Tyrosine | 1990 |
N-acetyl-L-tyrosine and N-acetyl-L-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans.
Topics: Acetylcysteine; Adult; Amino Acids, Essential; Biological Availability; Cysteine; Female; Humans; Infusions, Intravenous; Kidney; Male; Parenteral Nutrition, Total; Tyrosine | 1989 |
[Utilization of N-acetylated amino acids in solutions for intravenous feeding. Cleavage of N-acetyltyrosine and N-acetylcysteine in rat tissues].
Topics: Acetylcysteine; Amidohydrolases; Animals; Cytosol; Kidney; Liver; Muscles; Organ Specificity; Parenteral Nutrition; Rats; Tyrosine | 1982 |
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates | 1994 |
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1995 |
Stimulation of p42 and p44 mitogen-activated protein kinases by reactive oxygen species and nitric oxide in hippocampus.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Free Radical Scavengers; Hippocampus; Hydrogen Peroxide; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitric Oxide; Organ Culture Techniques; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine | 1998 |
Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells.
Topics: Acetylcysteine; Androstadienes; Cell Differentiation; Chelating Agents; Cysteine; Dithiothreitol; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Sulfhydryl Reagents; Tyrosine; Unithiol; Wortmannin | 1998 |
Proteasome blockers inhibit protein breakdown in skeletal muscle after burn injury in rats.
Topics: Acetylcysteine; Animals; Burns; Culture Techniques; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Lactones; Leupeptins; Male; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tyrosine; Ubiquitins | 1998 |
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein.
Topics: Acetylcysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; Immediate-Early Proteins; Leupeptins; Milk Proteins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Receptors, Erythropoietin; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Tyrosine; Ubiquitins | 1998 |
Redox-sensitive events in Fas-induced apoptosis in human NK cells include ceramide generation and protein tyrosine dephosphorylation.
Topics: Acetylcysteine; Antibodies, Monoclonal; Apoptosis; Buthionine Sulfoximine; Caspase 3; Caspases; Cells, Cultured; Ceramides; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Glutamate-Cysteine Ligase; Glutathione; Humans; Interleukin-2; Killer Cells, Natural; Membrane Glycoproteins; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Signal Transduction; Sulfhydryl Compounds; Transfection; Tyrosine | 1998 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation.
Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions | 2000 |
A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5.
Topics: Acetylcysteine; Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Leupeptins; Milk Proteins; Multienzyme Complexes; Phosphorylation; Phosphotyrosine; Proteasome Endopeptidase Complex; Protein Structure, Secondary; STAT5 Transcription Factor; Trans-Activators; Transcriptional Activation; Tyrosine | 2000 |
Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antifungal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radicals; Glutathione Transferase; Heart Ventricles; Hydrogen Peroxide; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Methacrylates; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Osmotic Pressure; Oxidative Stress; Phenylephrine; Phosphorylation; Protein Kinases; Rats; Signal Transduction; Thiazoles; Time Factors; Tyrosine; Uncoupling Agents | 2000 |
Beneficial effects of n-acetylcysteine on ischaemic brain injury.
Topics: Acetylcysteine; Animals; Brain; Brain Edema; Brain Ischemia; Free Radical Scavengers; Gerbillinae; Male; Malondialdehyde; Motor Activity; Nitric Oxide; Peroxidase; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Time Factors; Tyrosine | 2000 |
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Aorta; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Ileum; In Vitro Techniques; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitrites; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splenic Artery; Tyrosine; Vasodilation | 2000 |
Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspases; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Immunoblotting; Interferon-alpha; Janus Kinase 1; Jurkat Cells; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Ribonucleases; Signal Transduction; STAT1 Transcription Factor; STAT2 Transcription Factor; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; TYK2 Kinase; Tyrosine; Vanadates | 2001 |
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Erythrocytes; Free Radical Scavengers; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung; Macrophages; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite.
Topics: Acetylcysteine; Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Ferritins; Free Radicals; Hydrogen Peroxide; Liver; Multienzyme Complexes; Naphthols; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteins; Rats; Singlet Oxygen; Tyrosine | 2001 |
Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production.
Topics: Acetylcysteine; Cell Physiological Phenomena; Cell Survival; Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Damage; Free Radicals; Glutathione; Humans; Lipid Metabolism; Multienzyme Complexes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrogen; Oxidative Stress; Proteasome Endopeptidase Complex; Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Cells, Cultured; Tyrosine; Ubiquitins | 2001 |
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenoviridae; Amino Acids; Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cytosol; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Glucose; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tyrosine | 2001 |
Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats.
Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Drug Synergism; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypertension; In Vitro Techniques; Isoproterenol; Male; Malondialdehyde; Nitrates; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents; Vasomotor System | 2001 |
Effect of N-acetylcysteine on gentamicin-mediated nephropathy in rats.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Gentamicins; Kidney; Male; Malondialdehyde; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Tyrosine | 2001 |
Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress.
Topics: Acetylcysteine; Antioxidants; DNA-Binding Proteins; Hepatitis B virus; Humans; Mitochondria; NF-kappa B; Oxidative Stress; Phosphorylation; Pyrrolidines; STAT3 Transcription Factor; Superoxide Dismutase; Thiocarbamates; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Viral Regulatory and Accessory Proteins | 2001 |
Radical scavengers protect murine lungs from endotoxin-induced hyporesponsiveness to inhaled nitric oxide.
Topics: Acetylcysteine; Administration, Inhalation; Animals; Female; Free Radical Scavengers; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Reactive Oxygen Species; Tyrosine; Vasodilation | 2002 |
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production.
Topics: Acetylcysteine; Animals; Catechin; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Insulin; Liver; Liver Neoplasms, Experimental; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Superoxide Dismutase; Tumor Cells, Cultured; Tyrosine | 2002 |
Reversible labeling of tyrosine residue in peptide using 4-fluoro-7-nitro-2,1,3-benzoxadiazole and N-acetyl-L-cysteine.
Topics: 4-Chloro-7-nitrobenzofurazan; Acetylcysteine; Chromatography; Molecular Structure; Peptides; Tyrosine | 2003 |
Cyclosporin A disrupts bradykinin signaling through superoxide.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Animals; Antioxidants; Blotting, Western; Bradykinin; Cyclic GMP; Cyclosporine; Enzyme Activation; Free Radical Scavengers; GTP-Binding Proteins; Guanylate Cyclase; LLC-PK1 Cells; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Onium Compounds; Phospholipases; Quercetin; Receptor, Bradykinin B2; Receptors, Bradykinin; Signal Transduction; Solubility; Superoxides; Swine; Tyrosine; Vitamin K 3 | 2003 |
Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; DNA-Binding Proteins; Down-Regulation; Enzyme Induction; Glutathione; HT29 Cells; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-6; Janus Kinase 2; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisomes; Phosphoproteins; Phosphorylation; Prostaglandin D2; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2003 |
Phosphoinositide 3-kinase activity leads to silica-induced NF-kappaB activation through interacting with tyrosine-phosphorylated I(kappa)B-alpha and contributing to tyrosine phosphorylation of p65 NF-kappaB.
Topics: Acetylcysteine; Androstadienes; Animals; Antioxidants; Blotting, Western; Cell Line; Cell Nucleus; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Lipopolysaccharides; Mice; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Pyrrolidines; Reactive Oxygen Species; Silicon Dioxide; Superoxide Dismutase; Thiocarbamates; Time Factors; Tyrosine; Wortmannin | 2003 |
Synthesis and selective in vitro anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol.
Topics: 3T3 Cells; Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cysteamine; Glutathione; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Melanoma; Melanoma, Experimental; Mice; Models, Chemical; Monophenol Monooxygenase; Phenols; Stereoisomerism; Time Factors; Tyrosine | 2003 |
Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers.
Topics: Acetylcysteine; Antigen-Presenting Cells; Antioxidants; Cells, Cultured; Cysteine; Dermatitis, Contact; Glutathione; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Picryl Chloride; Sulfhydryl Compounds; Tyrosine | 2003 |
Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells.
Topics: Acetylcysteine; Bronchi; Cell Line; Cycloheximide; Epithelial Cells; Folic Acid Antagonists; Free Radical Scavengers; Glucose; Humans; Hypoglycemia; Interleukin-1; Interleukin-8; Lipopolysaccharides; Methotrexate; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pulmonary Alveoli; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Insulin inhibition of protein degradation in cells expressing wild-type and mutant insulin receptors.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Insulin; Leucine; Molecular Sequence Data; Mutation; Proteins; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Transfection; Tyrosine | 2003 |
Oxidative stress induces protein kinase C-mediated activation loop phosphorylation and nuclear redistribution of protein kinase D.
Topics: Acetylcysteine; Amino Acid Substitution; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Enzyme Activation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Protein Kinase C; Recombinant Proteins; Serine; Signal Transduction; Swiss 3T3 Cells; Transfection; Tyrosine | 2004 |
N-acetylcysteine inhibits peroxynitrite-mediated damage in oleic acid-induced lung injury.
Topics: Acetylcysteine; Animals; Female; Lung; Malondialdehyde; Microscopy; Oleic Acid; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine | 2004 |
Aldosteronism and a proinflammatory vascular phenotype: role of Mg2+, Ca2+, and H2O2 in peripheral blood mononuclear cells.
Topics: Acetylcysteine; Amlodipine; Animals; Biomarkers; Body Weight; Calcium; Dietary Supplements; Hydrogen Peroxide; Hyperaldosteronism; Leukocytes, Mononuclear; Magnesium; Male; Oxidation-Reduction; Oxidative Stress; Phenotype; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tyrosine; Vasculitis | 2005 |
Nitrotyrosine-modified proteins and oxidative stress induced by diesel exhaust particles.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Cell Line; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Protein Processing, Post-Translational; Proteins; Tyrosine; Vehicle Emissions | 2005 |
The antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Apolipoproteins E; Arteriosclerosis; Body Weight; Collagen; Female; Mice; Mice, Knockout; Tyrosine; Uremia | 2005 |
The effect of N-acetylcysteine on cardiac contractility to dobutamine in rats with streptozotocin-induced diabetes.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dinoprost; Dobutamine; Dose-Response Relationship, Drug; Heart Rate; Immunohistochemistry; Male; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tyrosine | 2005 |
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Aldehydes; Apoptosis; Cell Death; Cell Line, Tumor; Drug Resistance; Enzyme Inhibitors; Genetic Predisposition to Disease; Glutamic Acid; Guanine; Humans; Hydrogen Peroxide; Mutation; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Substantia Nigra; Tyrosine; Ubiquitin-Protein Ligases | 2005 |
Respiratory loading intensity and diaphragm oxidative stress: N-acetyl-cysteine effects.
Topics: Acetylcysteine; Animals; Antioxidants; Diaphragm; Dogs; Male; Muscle Fatigue; Oxidative Stress; Protein Carbonylation; Proteins; Respiration; Tyrosine; Work of Breathing | 2006 |
Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity.
Topics: Acetylcysteine; Amides; Amyloid beta-Peptides; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Neurons; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
Are oxidative mechanisms primary in ethanol induced Purkinje neuron death of the neonatal rat?
Topics: Acetylcysteine; Animals; Animals, Newborn; Cell Count; Cell Death; Cerebellum; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Male; Peroxynitrous Acid; Pregnancy; Purkinje Cells; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2006 |
GEA3162, a nitric oxide-releasing agent, activates non-store-operated Ca2+ entry and inhibits store-operated Ca2+ entry pathways in neutrophils through thiol oxidation.
Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Male; Membrane Potentials; Mercaptoethanol; Mitochondrial Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Donors; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors; Triazoles; Tyrosine; Unithiol | 2006 |
Nitration of cardiac proteins is associated with abnormal cardiac chronotropic responses in rats with biliary cirrhosis.
Topics: Acetylcysteine; Animals; Enzyme Inhibitors; Heart Rate; Immunohistochemistry; Liver Cirrhosis, Biliary; Male; Microscopy, Electron; Muscle Proteins; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Osmolar Concentration; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tyrosine | 2006 |
Degradation of insulin-like growth factor-I receptor occurs via ubiquitin-proteasome pathway in human lung cancer cells.
Topics: Acetylcysteine; Cell Line; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Down-Regulation; Humans; Kinetics; Lung Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Receptor, IGF Type 1; Tyrosine; Ubiquitin | 2006 |
N-acetylcysteine prevents nitrosative stress-associated depression of blood pressure and heart rate in streptozotocin diabetic rats.
Topics: Acetylcysteine; Animals; Blood Glucose; Blood Pressure; Blotting, Western; Cholesterol; Diabetes Mellitus, Experimental; Free Radical Scavengers; Heart Rate; Immunohistochemistry; Insulin; Isoprostanes; Male; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Stress, Physiological; Triglycerides; Tyrosine | 2006 |
Role of peroxynitrite in endothelial damage mediated by Cyclosporine A.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Cattle; Cell Membrane; Cell Survival; Cells, Cultured; Cyclosporine; Endothelial Cells; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Nitric Oxide; Peroxynitrous Acid; Superoxide Dismutase; Tyrosine | 2007 |
Which comes first: renal inflammation or oxidative stress in spontaneously hypertensive rats?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Age Factors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Disease Progression; DNA Damage; Glutathione; Hypertension; Kidney Cortex; Male; NADPH Oxidases; Nephritis; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Tyrosine | 2007 |
Peroxynitrite oxidizes erythrocyte membrane band 3 protein and diminishes its anion transport capacity.
Topics: Acetylcysteine; Anion Exchange Protein 1, Erythrocyte; Anions; Catechin; Erythrocytes; Hemoglobins; Humans; Ion Transport; Nitrates; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Tyrosine | 2007 |
Determinants of growth hormone receptor down-regulation.
Topics: Acetylcysteine; Animals; Cell Line; Chloroquine; Cycloheximide; Down-Regulation; Human Growth Hormone; Humans; Janus Kinase 2; Lysosomes; Mice; Mutation; Phosphorylation; Proteasome Inhibitors; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Rabbits; Receptors, Somatotropin; Recombinant Proteins; Transfection; Tyrosine | 2007 |
Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Antibodies; Blotting, Western; Cadherins; Cell Adhesion; Cell Line, Tumor; Culture Media, Conditioned; DNA, Neoplasm; Dogs; Down-Regulation; Extracellular Matrix; Hepatocyte Growth Factor; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Phosphorylation; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-met; Tyrosine | 2008 |
Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Cells, Cultured; Chloroform; Cyclosporine; Female; Glutathione; Hepatocytes; Membrane Potential, Mitochondrial; Mice; Mice, Inbred Strains; Mitochondria, Liver; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine | 2007 |
Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets.
Topics: Acetylcysteine; Animals; Animals, Newborn; Carotid Arteries; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen Peroxide; Hypoxia-Ischemia, Brain; Lactates; Nitric Oxide; Oxidative Stress; Oxygen; Random Allocation; Regional Blood Flow; Swine; Tyrosine | 2008 |
Effects of N-acetylcysteine administration in hepatic microcirculation of rats with biliary cirrhosis.
Topics: Acetylcysteine; Animals; Antioxidants; Bile Ducts; Disease Models, Animal; Free Radical Scavengers; Ligation; Liver Circulation; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Microcirculation; Oxidants; Peptide Fragments; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Thromboxane-A Synthase; Tyrosine; Vascular Resistance | 2008 |
Protein oxidation under extremely low frequency electric field in guinea pigs. Effect of N-acetyl-L-cysteine treatment.
Topics: Acetylcysteine; Analysis of Variance; Animals; Electromagnetic Fields; Free Radical Scavengers; Guinea Pigs; Hydroxyproline; Liver; Male; Oxidation-Reduction; Protein Carbonylation; Proteins; Radiation-Protective Agents; Random Allocation; Tyrosine | 2009 |
Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Line, Transformed; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation; Herbicides; Hydrogen Peroxide; Mesencephalon; Neurons; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Paraquat; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tyrosine; Vitamin E | 2009 |
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Glutathione; Hyperoxia; Hypoxia; Ischemia; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Protective Agents; Retinal Neovascularization; Retinal Vessels; Tyrosine | 2010 |
Antioxidant therapy reverses impaired graft healing in hypercholesterolemic rabbits.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta, Abdominal; Blood Vessel Prosthesis Implantation; Cell Movement; Cell Proliferation; Cholesterol; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; Hyperplasia; Macrophages; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Rabbits; Thiobarbituric Acid Reactive Substances; Tyrosine; Wound Healing | 2010 |
N-acetylcysteine impairs survival of luteal cells through mitochondrial dysfunction.
Topics: Acetylcysteine; Animals; Aurintricarboxylic Acid; Biomarkers; Cattle; Cell Nucleus; Cell Survival; Female; Flow Cytometry; Fluorescence; Intracellular Space; Lipid Peroxides; Luteal Cells; Membrane Potential, Mitochondrial; Mitochondria; Molecular Imaging; Oxidation-Reduction; Progesterone; Reactive Oxygen Species; Rhodamines; Signal Transduction; Steroids; Time Factors; Tyrosine | 2010 |
Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Apoptosis; Caspase 3; Catheter Ablation; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Female; Histones; HSP70 Heat-Shock Proteins; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Inbred F344; Tyrosine | 2010 |
Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Biological Transport; Blood Pressure; Cysteine; Cystine; Electric Stimulation; Glucose; Glutathione; Heart Rate; Hindlimb; Infusions, Intra-Arterial; Male; Muscle Contraction; Muscle Fatigue; Muscle Strength; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Regional Blood Flow; Time Factors; Tyrosine; Vascular Resistance | 2010 |
Science to practice: will randomized prospective clinical trials be necessary for RF ablation of large liver tumors with liposomal doxorubicin?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Aldehydes; Animals; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Catheter Ablation; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Histones; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Oxidative Stress; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Tyrosine | 2010 |
Nerve growth factor attenuates oxidant-induced β-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids.
Topics: Acetylcysteine; Aged; Alzheimer Disease; Amyloid beta-Peptides; Cell Survival; Cells, Cultured; DNA, Mitochondrial; Female; Glutathione; Humans; Hybrid Cells; Male; Mitochondria; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Neurons; NF-kappa B; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine | 2010 |
Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease.
Topics: Acetylcysteine; Animals; Benzamides; Brain; Case-Control Studies; Cell Line; Disease Models, Animal; Dopamine; Drug Administration Schedule; Free Radical Scavengers; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Imatinib Mesylate; Immunoprecipitation; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Oxidative Stress; Peptide Elongation Factors; Phosphorylation; Piperazines; Polyethylene Glycols; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; RNA, Small Interfering; Statistics, Nonparametric; Transfection; Tumor Suppressor Proteins; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination | 2011 |
Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: a comparison with n-acetylcysteine.
Topics: Acetophenones; Acetylcysteine; Acute-Phase Proteins; Animals; Apoptosis; Contrast Media; Cytosine; Diabetic Nephropathies; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Iopamidol; Isoenzymes; Kidney Glomerulus; Lipocalin-2; Lipocalins; Male; NADPH Oxidases; Poly(ADP-ribose) Polymerases; Potassium; Proto-Oncogene Proteins; Rats; Rats, Wistar; Sodium; Time Factors; Tyrosine | 2012 |
Chronic hypoxia increases peroxynitrite, MMP9 expression, and collagen accumulation in fetal guinea pig hearts.
Topics: Acetylcysteine; Animals; Body Weight; Collagen; Female; Fetal Heart; Guinea Pigs; Hypoxia; Lipid Peroxidation; Matrix Metalloproteinase 9; Nitric Oxide Synthase Type II; Organ Size; Peroxynitrous Acid; Pregnancy; Tyrosine | 2012 |
Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100% oxygen.
Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Asphyxia; Bronchoalveolar Lavage; DNA Primers; Enzyme-Linked Immunosorbent Assay; Hyaluronic Acid; Interleukin-1beta; Lung; Oxidative Stress; Oxygen Inhalation Therapy; Peroxynitrous Acid; Real-Time Polymerase Chain Reaction; Sus scrofa; Tumor Necrosis Factor-alpha; Tyrosine | 2012 |
Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Atherosclerosis; Cell Cycle Proteins; Cysteine; Female; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Free Radical Scavengers; Hematopoietic Stem Cells; Insulin; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Neutrophils; Nitrogen; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Tyrosine | 2013 |
Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.
Topics: Acetylcysteine; Adherens Junctions; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Breast Neoplasms; Cadherins; Cell Movement; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Male; Ovarian Neoplasms; Plant Extracts; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 2013 |
N-acetyl cysteine regulates the phosphorylation of JAK proteins following CD40-activation of human memory B cells.
Topics: Acetylcysteine; B-Lymphocytes; CD40 Antigens; Cell Differentiation; Cells, Cultured; Humans; Immunologic Memory; Janus Kinases; Lymphocyte Activation; Phosphorylation; STAT3 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Tyrosine | 2014 |
N-acetylcysteine administration confers lung protection in different phases of lung ischaemia-reperfusion injury.
Topics: Acetylcysteine; Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Cytoprotection; Disease Models, Animal; Hemodynamics; I-kappa B Kinase; Inflammation Mediators; Interleukin-1beta; Lipid Peroxidation; Lung; Lung Injury; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells.
Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Caveolin 1; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydrogen Peroxide; Insulin-Secreting Cells; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microscopy, Confocal; Oxidants; Palmitates; Phosphorylation; Pyrimidines; Reactive Oxygen Species; Sphingosine; src-Family Kinases; Tyrosine | 2015 |
Influence of N- acetylcysteine on oxidative stress in slow-twitch soleus muscle of heart failure rats.
Topics: Acetylcysteine; Animals; Ethidium; Free Radical Scavengers; Glutathione Peroxidase; Heart Failure; Heart Ventricles; Male; Malondialdehyde; Muscle, Skeletal; Myocardial Infarction; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2015 |
N-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms.
Topics: Acetylcysteine; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Cell Migration Assays, Leukocyte; Cytokines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Edema; Expectorants; Leukocyte Count; Lung; Meconium Aspiration Syndrome; Pilot Projects; Pulmonary Surfactants; Rabbits; Random Allocation; Respiratory Function Tests; Thiobarbituric Acid Reactive Substances; Tyrosine | 2014 |
Autophagy attenuates noise-induced hearing loss by reducing oxidative stress.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Autophagy; Hair Cells, Auditory, Outer; Hearing Loss, Noise-Induced; Male; Mice; Microtubule-Associated Proteins; Oxidative Stress; Sirolimus; Tyrosine | 2015 |
The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania.
Topics: Acetylcysteine; Aldehydes; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; Deferoxamine; Disease Models, Animal; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Sleep Deprivation; Tyrosine | 2015 |
N-acetylcysteine modulates angiogenesis and vasodilation in stomach such as DNA damage in blood of portal hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Comet Assay; Disease Models, Animal; DNA Damage; Gastric Mucosa; Hypertension, Portal; Immunohistochemistry; Male; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; Portal Pressure; Rats, Wistar; Stomach; Tyrosine; Vascular Endothelial Growth Factor A; Vasodilation | 2015 |
Sensing tyrosine enantiomers by using chiral CdSe/CdS quantum dots capped with N-acetyl-l-cysteine.
Topics: Acetylcysteine; Cadmium Compounds; Quantum Dots; Selenium Compounds; Stereoisomerism; Sulfides; Tyrosine | 2017 |
Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Citrate (si)-Synthase; Citric Acid Cycle; Creatine Kinase; Deferoxamine; Electron Transport; Energy Metabolism; Male; Oxidative Stress; Rats; Rats, Wistar; Succinate Dehydrogenase; Tyrosine; Tyrosinemias | 2017 |
Importance of NADPH oxidase-mediated redox signaling in the detrimental effect of CRP on pancreatic insulin secretion.
Topics: Acetophenones; Acetylcysteine; Animals; C-Reactive Protein; Cell Line; Dose-Response Relationship, Drug; Etanercept; Gene Expression Regulation; Guanidines; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred BALB C; NADPH Oxidases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Oxidation-Reduction; Proline; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine | 2017 |
Antioxidants Reverse the Changes in the Cholinergic System Caused by L-Tyrosine Administration in Rats.
Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Brain; Choline O-Acetyltransferase; Deferoxamine; Male; Memory; Neuroprotective Agents; Rats, Wistar; Tyrosine | 2018 |
PEGylated NALC-functionalized gold nanoparticles for colorimetric discrimination of chiral tyrosine.
Topics: Acetylcysteine; Colorimetry; Gold; Metal Nanoparticles; Polyethylene Glycols; Tyrosine | 2020 |
Adding of neurotensin to non-small cell lung cancer cells increases tyrosine phosphorylation of HER3.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Antibodies, Monoclonal; Antioxidants; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Neuregulins; Neurotensin; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-3; Receptors, Neurotensin; Superoxides; Tyrosine | 2022 |