acetylcysteine has been researched along with trichostatin a in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (75.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davie, JR; Lucktong, A; Melkoumian, ZK; Moniwa, M; Strobl, JS; Zhou, Q | 1 |
| Chen, CY; Chen, JS; Faller, DV; Liou, JS | 1 |
| Chen, J; Kang, J; Lin, C; Liu, Q; Zhang, D | 1 |
| Csordas, A; Galfi, P; Jakus, J; Molnar, T; Neogrady, S | 1 |
| Alao, JP; Coombes, RC; Lam, EW; Stavropoulou, AV; Vigushin, DM | 1 |
| Guo, SW; Wu, Y | 1 |
| Bai, H; Chen, J; Kang, J; Wang, C | 1 |
| Chen, J; Jia, J | 1 |
| Ha, H; Kim, YO; Lee, HB; Noh, H; Oh, EY; Seo, JY; Yu, MR | 1 |
| Hiraku, Y; Ikemura, K; Iwamoto, T; Kagawa, Y; Kawanishi, S; Mizutani, H; Murata, M; Okuda, M; Tada-Oikawa, S | 1 |
| Park, WH; You, BR | 1 |
| Cao, W; Kan, Y; Koumbadinga, GA; Lei, L; Lobo, VG; Mahmood, N; Xie, J; Yao, X; Zhang, S | 1 |
12 other study(ies) available for acetylcysteine and trichostatin a
| Article | Year |
|---|---|
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1.
Topics: Acetylation; Acetylcysteine; Animals; Anti-Bacterial Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Division; Chickens; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeleton; Down-Regulation; Enzyme Inhibitors; Female; G1 Phase; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunoblotting; Keratins; Leupeptins; Multienzyme Complexes; Peptides; Phosphorylation; Proteasome Endopeptidase Complex; Quinidine; Retinoblastoma Protein; Time Factors; Tumor Cells, Cultured | 2000 |
Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species.
Topics: 3T3 Cells; Acetylcysteine; Animals; Antifungal Agents; Apoptosis; Butyrates; Cell Cycle; Cell Separation; Cell Survival; Cyclosporins; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Fluoresceins; Free Radical Scavengers; Glyceryl Ethers; Hydrogen Peroxide; Hydroxamic Acids; Mice; Mitosis; Oxygen; Protein Kinase C; ras Proteins; Reactive Oxygen Species; Time Factors; Transfection; Up-Regulation | 2000 |
Antioxidants and trichostatin A synergistically protect against in vitro cytotoxicity of Ni2+ in human hepatoma cells.
Topics: Acetylation; Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione; Hepatocytes; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Liver Neoplasms; Nickel; Reactive Oxygen Species | 2005 |
Divergent effects of resveratrol, a polyphenolic phytostilbene, on free radical levels and type of cell death induced by the histone deacetylase inhibitors butyrate and trichostatin A.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Butyrates; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Female; Free Radicals; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intestinal Mucosa; Kinetics; Mammary Neoplasms, Animal; Mice; Necrosis; Resveratrol; Stilbenes | 2005 |
Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.
Topics: Acetylcysteine; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cyclin D1; Cytoplasm; Enzyme Inhibitors; Exportin 1 Protein; Fatty Acids, Unsaturated; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Karyopherins; Leupeptins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; RNA Interference; Transfection; Ubiquitin | 2006 |
Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780.
Topics: Acetylcysteine; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endometriosis; Endometrium; Enzyme Inhibitors; Estradiol; Fas Ligand Protein; fas Receptor; Female; Fulvestrant; Humans; Hydrogen Peroxide; Hydroxamic Acids; Mifepristone; Norpregnadienes; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Stromal Cells | 2006 |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells.
Topics: Acetylation; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Drug Synergism; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Indicators and Reagents; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Protein Synthesis Inhibitors; Reactive Oxygen Species | 2006 |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death.
Topics: Acetylation; Acetylcysteine; Cell Death; Cell Proliferation; Free Radical Scavengers; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Leukemia; Lipid Peroxidation; Malondialdehyde; Quercetin; Reactive Oxygen Species | 2008 |
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.
Topics: Acetylcysteine; Amides; Animals; Antioxidants; Biphenyl Compounds; Cell Line; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Kidney; Male; Mice; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recombinant Proteins; Repressor Proteins; RNA Interference; RNA, Messenger; Transforming Growth Factor beta1; Valproic Acid | 2009 |
Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Depsipeptides; Glutathione; Histone Deacetylase Inhibitors; Humans; Hydrogen Peroxide; Hydroxamic Acids | 2010 |
Trichostatin A induces apoptotic cell death of HeLa cells in a Bcl-2 and oxidative stress-dependent manner.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Proliferation; Flow Cytometry; Glutathione; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Membrane Potential, Mitochondrial; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA, Small Interfering | 2013 |
Increased stability of heterogeneous ribonucleoproteins by a deacetylase inhibitor.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Heterogeneous-Nuclear Ribonucleoproteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mutation; PC12 Cells; Protein Stability; Rats; RNA Splicing; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2015 |