acetylcysteine has been researched along with trichloroethylene in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Boogaard, PJ; Commandeur, JN; Mulder, GJ; Vermeulen, NP | 1 |
| Bakke, JE; Davison, KL | 1 |
| Dekant, W; Henschler, D; Koob, M | 1 |
| Conti, G; Pelaia, P; Sposato, M; Volturo, P | 1 |
| Calabrese, SR; Emilio, G; Giuffrida, L; Imberti, R; Marchi, L | 1 |
| Dekant, W; Henschler, D; Metzler, M | 1 |
| Birner, G; Dekant, W; Henschler, D; Vamvakas, S | 1 |
| Bernauer, U; Birner, G; Dekant, W; Henschler, D | 1 |
| Abuladze, N; Avliyakulov, NK; Bondar, G; Dekant, W; Faull, K; Koag, MC; Kurtz, I; Newman, D; Pushkin, A; Scholz, K; Tsirulnikov, K; Zhu, Q | 1 |
| Elfarra, AA; Irving, RM | 1 |
| Elfarra, AA; Irving, RM; Pinkerton, ME | 1 |
| Ansari, GA; Khan, MF; Ma, H; Wang, G; Wang, J | 1 |
| Chiu, W; Furuya, S; Luo, YS; Rusyn, I | 1 |
| Khan, MF; Ma, H; Wang, G; Wang, J | 1 |
| Boor, PJ; Du, X; Khan, MF; Liang, Y; Sun, J; Wang, G; Wang, H | 1 |
| Aniagu, S; Chen, T; Ji, C; Jiang, Y; Jin, H; Ren, F; Tong, J | 1 |
| Bergin, IL; Bjork, F; Lash, LH; Loch-Caruso, R; Su, AL | 1 |
| Bakulski, KM; Boldenow, E; Bridges, D; Colacino, JA; Dou, JF; Elkin, ER; Harris, SM; Loch-Caruso, R; Padmanabhan, V; Su, AL | 1 |
| Lash, LH; Loch-Caruso, R; Su, AL | 1 |
1 review(s) available for acetylcysteine and trichloroethylene
| Article | Year |
|---|---|
Role of reactive metabolites in the circulation in extrahepatic toxicity.
Topics: Acetylcysteine; Cysteine; Humans; Kidney; Liver; Trichloroethylene | 2012 |
21 other study(ies) available for acetylcysteine and trichloroethylene
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.
Topics: Acetylcysteine; Animals; Cysteine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Stereoisomerism; Trichloroethylene | 1991 |
Elimination of 14C by calves, pigs and rats renally perfused with radiolabelled dichlorovinyl or acetamide substrates.
Topics: Acetanilides; Acetylation; Acetylcysteine; Animals; Carbon Radioisotopes; Cattle; Cysteine; Herbicides; Iodoacetamide; Kidney; Perfusion; Rats; Rats, Inbred Strains; Swine; Trichloroethylene | 1990 |
Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation.
Topics: Acetylcysteine; Animals; Bile; Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Male; Microsomes, Liver; Molecular Structure; Rats; Rats, Inbred Strains; Trichloroethylene | 1990 |
[A new therapeutic approach in the treatment of acute trichloroethylene poisoning. First clinical results].
Topics: Acetylcysteine; Adolescent; Adult; Humans; Male; Plasmapheresis; Suicide, Attempted; Trichloroethylene | 1988 |
[Acute poisoning with solvents: chlorinated aliphatic hydrocarbons].
Topics: Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Antidotes; Child; Child, Preschool; Female; Humans; Hydrocarbons, Chlorinated; Infant; Male; Middle Aged; Prognosis; Propane; Retrospective Studies; Trichloroethylene | 1987 |
Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats.
Topics: Acetylcysteine; Animals; Biotransformation; Kidney Neoplasms; Male; Rats; Rats, Inbred Strains; Trichloroethylene | 1986 |
Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure.
Topics: Acetylcysteine; Animals; Female; Humans; In Vitro Techniques; Kidney; Male; Mice; Mutagens; Occupational Exposure; Rats; Rats, Wistar; Risk Factors; Trichloroethylene | 1993 |
Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
Topics: Acetylcysteine; Administration, Inhalation; Adult; Aged; Animals; Biotransformation; Cysteine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Male; Middle Aged; Rats; Trichloroethylene | 1996 |
Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).
Topics: Acetylcysteine; Animals; Biological Transport; Cells, Cultured; Kidney Tubules, Proximal; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rabbits; RNA, Messenger; Transport Vesicles; Trichloroethylene; Vesicle-Associated Membrane Protein 2 | 2010 |
Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, a potential reactive metabolite of trichloroethylene.
Topics: Acetylcysteine; Animals; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Trichloroethylene | 2013 |
N-Acetylcysteine protects against trichloroethene-mediated autoimmunity by attenuating oxidative stress.
Topics: Acetylcysteine; Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Female; Interleukin-17; Kidney; Lipid Peroxidation; Liver; Mice; Mice, Inbred MRL lpr; Oxidative Stress; Protein Carbonylation; RNA, Messenger; Spleen; Trichloroethylene | 2013 |
Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.
Topics: Acetylcysteine; Animals; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred Strains; Signal-To-Noise Ratio; Tissue Distribution; Trichloroethylene | 2018 |
Contribution of poly(ADP-ribose)polymerase-1 activation and apoptosis in trichloroethene-mediated autoimmunity.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antibodies, Antinuclear; Apoptosis; Autoimmunity; bcl-2-Associated X Protein; Deoxyguanosine; DNA Damage; Female; Liver; Mice, Knockout; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins c-bcl-2; Solvents; Trichloroethylene | 2019 |
Redox regulation of hepatic NLRP3 inflammasome activation and immune dysregulation in trichloroethene-mediated autoimmunity.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Autoimmune Diseases; Female; Free Radical Scavengers; Inflammasomes; Inflammation; Liver; Mice; Mice, Inbred Strains; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Trichloroethylene | 2019 |
AHR-mediated oxidative stress contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish embryos.
Topics: Acetylcysteine; Animals; Azo Compounds; Cardiotoxicity; DNA Damage; Embryo, Nonmammalian; Embryonic Development; Heart; Heart Defects, Congenital; Oxidative Stress; Purines; Pyrazoles; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Trichloroethylene; Zebrafish; Zebrafish Proteins | 2020 |
N-Acetyl-L-cysteine and aminooxyacetic acid differentially modulate trichloroethylene reproductive toxicity via metabolism in Wistar rats.
Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutathione; Male; Oxidative Stress; Placenta; Pregnancy; Pregnancy Outcome; Rats; Rats, Wistar; Reproduction; Solvents; Trichloroethylene | 2021 |
Sexually concordant and dimorphic transcriptional responses to maternal trichloroethylene and/or N-acetyl cysteine exposure in Wistar rat placental tissue.
Topics: Acetylcysteine; Animals; Antioxidants; Female; Male; Placenta; Pregnancy; Rats; Rats, Wistar; Trichloroethylene | 2023 |
N-Acetyl-L-cysteine and aminooxyacetic acid differentially modulate toxicity of the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine in human placental villous trophoblast BeWo cells.
Topics: Acetylcysteine; Aminooxyacetic Acid; Cysteine; Cytochrome P-450 CYP3A; Female; Humans; Hydrogen Peroxide; Placenta; Pregnancy; RNA, Messenger; Trichloroethylene; Trophoblasts | 2023 |