acetylcysteine and tamoxifen

acetylcysteine has been researched along with tamoxifen in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's11 (61.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Han, XL; Liehr, JG1
Arnstein, HR; Cannon, M; Wiseman, H1
Sharma, M; Slocum, HK1
Dietrich, W; Huber, JC; Kolbus, A; Stonek, F; Tschugguel, W; Zhegu, Z1
Chang, T; Hayes, EC; Mitra, SW; Peekhaus, NT; Rohrer, SP; Schaeffer, JM; Wilkinson, HA1
Corbet, C; Heldt, JM; Jaouen, G; Jouy, N; Laïos, I; Leclercq, G; Lories, N; Toillon, RA; Vessières, A1
Kaufmann, Y; Klimberg, VS; Luo, S; Todorova, VK1
Dan, S; Guo, WZ; Ohashi, Y; Shiina, I; Uetake, S; Umeda, E; Wang, Y; Watanabe, C; Yamori, T1
Amarell, S; Cheng, Z; Linarelli, LE; Liu, D; Liu, L; Passaro, A; Zheng, L; Zou, P1
Ignatov, A; Kalinski, T; Nass, N; Roessner, A; Sel, S1
Cao, P; Gong, X; Lin, Y; Liu, L; Luo, M; Wu, T; Yang, Q; Zhou, L1

Reviews

1 review(s) available for acetylcysteine and tamoxifen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for acetylcysteine and tamoxifen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Induction of covalent DNA adducts in rodents by tamoxifen.
    Cancer research, 1992, Mar-01, Volume: 52, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cricetinae; DNA; Female; Kidney; Liver; Premedication; Rats; Rats, Inbred Strains; Tamoxifen

1992
Protection by glutathione against one component of the bimodal inhibition of growth by tamoxifen in Saccharomyces cerevisiae.
    Biochemical Society transactions, 1990, Volume: 18, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Breast Neoplasms; Cell Division; Glutathione; Humans; Saccharomyces cerevisiae; Tamoxifen; Tumor Cells, Cultured

1990
Prevention of quinone-mediated DNA arylation by antioxidants.
    Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Diethylstilbestrol; DNA Adducts; Horseradish Peroxidase; Hydrogen Peroxide; Male; Salmon; Tamoxifen; Testis

1999
Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Antibody Specificity; Arteries; Blotting, Western; Cell Nucleus; Cell-Free System; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation; Humans; Insulin; Kinetics; Multienzyme Complexes; Proteasome Endopeptidase Complex; Puromycin; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Uterus

2003
Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7.
    Journal of molecular endocrinology, 2004, Volume: 32, Issue:3

    Topics: Acetylcysteine; Animals; Breast Neoplasms; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Gene Expression Regulation; Genes, Reporter; Humans; Ligands; Point Mutation; Tamoxifen

2004
A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines.
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:5

    Topics: Acetylcysteine; Antioxidants; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cellular Senescence; Female; Ferrous Compounds; Humans; Reactive Oxygen Species; Receptors, Estrogen; Tamoxifen

2010
Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:2

    Topics: Acetylcysteine; Amino Acid Transport System ASC; Antioxidants; Apoptosis; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Estradiol; Female; Gene Expression; Glutamine; Glutathione; Humans; Minor Histocompatibility Antigens; Oxidative Stress; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen

2011
Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway.
    Biochemical pharmacology, 2013, Nov-01, Volume: 86, Issue:9

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Caspases; Cell Line, Tumor; Estrogen Receptor alpha; Free Radical Scavengers; Gene Knockdown Techniques; Gliosarcoma; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Protein Transport; Reactive Oxygen Species; Signal Transduction; Tamoxifen

2013
Tamoxifen reduces fat mass by boosting reactive oxygen species.
    Cell death & disease, 2015, Jan-08, Volume: 6

    Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Adiposity; Animals; Antioxidants; Apoptosis; Autophagy; Cell Count; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Male; Mice; Oxidative Stress; PPAR gamma; Reactive Oxygen Species; Tamoxifen

2015
Oxidative stress and glyoxalase I activity mediate dicarbonyl toxicity in MCF-7 mamma carcinoma cells and a tamoxifen resistant derivative.
    Biochimica et biophysica acta, 2016, Volume: 1860, Issue:6

    Topics: Acetylcysteine; Aldehydes; Drug Resistance, Neoplasm; Humans; Lactoylglutathione Lyase; MAP Kinase Signaling System; MCF-7 Cells; Oxidative Stress; Reactive Oxygen Species; Tamoxifen

2016
Tamoxifen Prevents D-galactosamine/Lipopolysaccharide-Induced Murine Acute Hepatic Failure through Inhibition of Oxidative Stress and Mmd-2 Upregulation.
    Immunological investigations, 2018, Volume: 47, Issue:6

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antigens, Differentiation; Antioxidants; Aspartate Aminotransferases; Catalase; Galactosamine; Glutathione Peroxidase; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Oxidative Stress; Superoxide Dismutase; Tamoxifen; Up-Regulation

2018