Compounds > acetylcysteine

acetylcysteine and tacrine

acetylcysteine has been researched along with tacrine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M1
Ekins, S; Williams, AJ; Xu, JJ1
Bastida, A; Chioua, M; Colmena, I; de los Ríos, C; Del Barrio, L; Gandía, L; González-Lafuente, L; López, MG; Marco-Contelles, J; Martín-de-Saavedra, MD; Romero, A; Samadi, A; Valderas, C; Villarroya, M1
Andrisano, V; Bartolini, M; Belluti, F; Bisi, A; Bottegoni, G; Cavalli, A; De Simone, A; Djemil, A; Gobbi, S; Montanari, S; Rampa, A; Tarozzi, A1
Bartolini, M; Bolognesi, ML; Guidotti, L; Hrabinova, M; Jeřábek, J; Korábečný, J; Kuča, K; Monti, B; Peña-Altamira, LE; Petralla, S; Roberti, M; Sepsova, V; Soukup, O; Uliassi, E1
Benek, O; Benkova, M; Dolezal, R; Hepnarova, V; Hrabinova, M; Janockova, J; Jun, D; Kobrlova, T; Korabecny, J; Kucera, T; Mezeiova, E; Prchal, L; Sobolova, K; Soukup, O1

Other Studies

9 other study(ies) available for acetylcysteine and tacrine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Cell Line, Tumor; Cholinesterase Inhibitors; Humans; Kinetics; Models, Molecular; Neuroprotective Agents; Nitriles; Tacrine; Vascular Diseases

2011
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease.
    European journal of medicinal chemistry, 2014, May-06, Volume: 78

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Antioxidants; Benzophenones; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2014
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Liver; Molecular Targeted Therapy; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Resveratrol; Stilbenes; Tacrine

2017
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
    European journal of medicinal chemistry, 2020, Oct-01, Volume: 203

    Topics: Berberine; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Prolyl Oligopeptidases

2020