acetylcysteine has been researched along with sulfasalazine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Breckenridge, AM; Coleman, MD; Hussain, F; Park, BK; Pirmohamed, M | 1 |
| Dunn, RJ | 1 |
| Haddad, JJ; Land, SC | 1 |
| Heidari, R; Najibi, A; Niknahad, H; Rahimi, HR; Shirazi Yeganeh, B; Taheri, V | 1 |
| Jin, B; Ondrejcak, T; Rowan, MJ; Zhang, D | 1 |
| Kasukabe, T; Kumakura, S; Yamaguchi, Y | 1 |
| Fujiwara, K; Imaue, S; Jawaid, P; Kondo, T; Mitsuhashi, Y; Moniruzzaman, R; Noguchi, K; Noguchi, M; Ogawa, R; Rehman, MU; Saitoh, JI; Tomihara, K; Zhao, QL | 1 |
| Li, Z; Long, Y; Luo, G; Shen, W; Shi, X; Zhang, X; Zheng, Z | 1 |
| Chen, MC; Hsu, CY; Hsu, LL; Lee, HC; Tseng, LM; Wang, SF | 1 |
1 review(s) available for acetylcysteine and sulfasalazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
14 other study(ies) available for acetylcysteine and sulfasalazine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes.
Topics: Acetylcysteine; Ascorbic Acid; Biotransformation; Cell Survival; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione; Humans; Ketoconazole; Leukocytes, Mononuclear; Methemoglobin; Microsomes, Liver; Sulfasalazine | 1991 |
Massive sulfasalazine and paracetamol ingestion causing acidosis, hyperglycemia, coagulopathy, and methemoglobinemia.
Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Acute Disease; Adult; Anti-Inflammatory Agents; Blood Coagulation Disorders; Blood Platelets; Drug Combinations; Drug Overdose; Humans; Hyperglycemia; Infusions, Intravenous; Male; Methemoglobinemia; Methylene Blue; Partial Thromboplastin Time; Sodium Bicarbonate; Suicide, Attempted; Sulfasalazine | 1998 |
The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting.
Topics: Acetylcysteine; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Buthionine Sulfoximine; Dipeptides; DNA Fragmentation; Enzyme Inhibitors; Epithelium; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Models, Biological; NF-kappa B; Oxidation-Reduction; Oxygen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pulmonary Alveoli; Pyrrolidines; Sulfasalazine; Thiocarbamates | 2000 |
Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antirheumatic Agents; Dithiothreitol; Drug Evaluation, Preclinical; Free Radical Scavengers; Male; Random Allocation; Rats, Sprague-Dawley; Sulfasalazine | 2016 |
Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xc- on the inhibition of hippocampal LTP by Aß.
Topics: Acetylcysteine; Amino Acid Transport Systems, Acidic; Amyloid beta-Peptides; Animals; Catheters, Indwelling; Central Nervous System Agents; Excitatory Postsynaptic Potentials; Glutathione; Hippocampus; Long-Term Potentiation; Male; Maleates; Peptide Fragments; Rats, Wistar; Sulfasalazine; Tumor Necrosis Factor-alpha | 2016 |
Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Dioxolanes; Diterpenes; Drug Synergism; Fibroblasts; Humans; Iron; Mice; Pancreatic Neoplasms; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Spiro Compounds; Sulfasalazine | 2018 |
Roles of intracellular and extracellular ROS formation in apoptosis induced by cold atmospheric helium plasma and X-irradiation in the presence of sulfasalazine.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Calcium; Caspase 3; Caspase 8; Cations, Divalent; Cell Line, Tumor; Cell Survival; DNA Fragmentation; fas Receptor; Gene Expression Regulation; HCT116 Cells; Helium; Humans; Hydroxyl Radical; Membrane Potential, Mitochondrial; Mitochondria; Oxidants; Oxidative Stress; Plasma Gases; Signal Transduction; Sulfasalazine; T-Lymphocytes; X-Rays | 2018 |
The X
Topics: Acetylcysteine; Amino Acid Transport System y+; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Glutathione; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Reactive Oxygen Species; Sulfasalazine; Transplantation, Heterologous | 2020 |
ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation.
Topics: Acetylcysteine; Amino Acid Transport System y+; AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Death; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glutamic Acid; Glutathione; Humans; Ketoglutaric Acids; Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering; Sirtuin 3; Sulfasalazine; Up-Regulation | 2020 |