acetylcysteine and succimer

acetylcysteine has been researched along with succimer in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's6 (30.00)18.2507
2000's8 (40.00)29.6817
2010's3 (15.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Corbella, J; Domingo, JL; Llobet, JM1
Ercal, N; Grannemann, NH; Hammond, TC; Matthews, RH; Spitz, DR; Treeratphan, P1
Bossuyt, PM; de Jong, JM; Louwerse, ES; Timmer, JG; Vyth, A1
Bowden, CA; Krenzelok, EP1
Erçal, N; Gürer, H; Neal, R; Ozgünes, H; Spitz, DR1
Cooper, K; Ercal, N; Gurer, H; Neal, R1
Flora, SJ1
Prasad, S; Siddiqui, MK; Singh, S; Srivastava, S; Tandon, SK1
Chatterjee, M; Dwivedi, VK; Khandekar, K; Mathur, N; Prasad, S; Singh, S; Tandon, SK1
Flora, SJ; Kannan, GM; Mehta, A; Pande, M1
Flora, SJ; Kannan, GM1
Luchese, C; Nogueira, CW; Rocha, JB; Santos, FW; Zeni, G1
Flora, G; Flora, SJ; Mishra, M; Saxena, G1
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N1
Gailer, J; Zeini Jahromi, E1
Abdel-Moneim, AM; Abu El-Saad, AM; Al-Kahtani, MA1
Aydin, A; Hasçiçek, AM; Hücümenoğlu, S; Huri, E; Karakan, T; Korkmaz, M; Özcan, S; Sunay, MM; Surer, H; Yardimci, İ1
Güven, D; Özbek, İ1

Reviews

4 review(s) available for acetylcysteine and succimer

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical applications of commonly used contemporary antidotes. A US perspective.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer

1997
Arsenic and lead induced free radical generation and their reversibility following chelation.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E

2007
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
    Journal of environmental biology, 2007, Volume: 28, Issue:2 Suppl

    Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc

2007

Trials

1 trial(s) available for acetylcysteine and succimer

ArticleYear
Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants.
    Journal of the neurological sciences, 1996, Volume: 139 Suppl

    Topics: Acetylcysteine; Administration, Oral; Amyotrophic Lateral Sclerosis; Antioxidants; Capsules; Chelating Agents; Dithioerythritol; Dithiothreitol; Free Radical Scavengers; Gastric Juice; Humans; Injections, Subcutaneous; Methionine; Succimer; Sulfhydryl Reagents; Survival Analysis

1996

Other Studies

15 other study(ies) available for acetylcysteine and succimer

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Comparative effects of repeated parenteral administration of several chelators on the distribution and excretion of cobalt.
    Research communications in chemical pathology and pharmacology, 1988, Volume: 60, Issue:2

    Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Edetic Acid; Glutathione; Injections, Intraperitoneal; Male; Pentetic Acid; Rats; Rats, Inbred Strains; Succimer

1988
In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2,3-dimercaptosuccinic acid or N-acetylcysteine.
    Free radical biology & medicine, 1996, Volume: 21, Issue:2

    Topics: Acetylcysteine; Animals; Brain; Cysteine; Glutathione; Lead; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Succimer

1996
Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats.
    Toxicology, 1998, Jul-17, Volume: 128, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Cell Count; Erythrocytes; Glutathione; Lead; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Inbred F344; Succimer

1998
Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lenses.
    Toxicology, 1998, Sep-15, Volume: 130, Issue:2-3

    Topics: Acetylcysteine; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Cysteine; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Lens, Crystalline; Male; Malondialdehyde; Organometallic Compounds; Oxidative Stress; Rats; Rats, Inbred F344; Succimer

1998
Arsenic-induced oxidative stress and its reversibility following combined administration of N-acetylcysteine and meso 2,3-dimercaptosuccinic acid in rats.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; 5-Aminolevulinate Synthetase; Acetylcysteine; Animals; Arsenic Poisoning; Brain; Chelating Agents; Erythrocytes; Free Radical Scavengers; Glutathione; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer

1999
Reversal of lead-induced oxidative stress by chelating agent, antioxidant, or their combination in the rat.
    Environmental research, 2002, Volume: 90, Issue:1

    Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Antioxidants; Brain; Catalase; Chelating Agents; Free Radical Scavengers; Glutathione; Kidney; Lead; Lead Poisoning; Male; Malondialdehyde; Oxidative Stress; Rats; Succimer

2002
Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat.
    Toxicology letters, 2003, Dec-10, Volume: 145, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Brain; Cadmium Chloride; Cadmium Poisoning; Catalase; Chelating Agents; Drug Synergism; Drug Therapy, Combination; Glutathione; Liver; Male; Malondialdehyde; Mannitol; Oxidative Stress; Rats; Succimer; Superoxide Dismutase

2003
Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2004, Volume: 50 Online Pub

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Chemistry; Chelating Agents; Kidney; Lead; Lead Poisoning; Liver; Male; Melatonin; Oxidative Stress; Rats; Succimer

2004
Combined administration of N-acetylcysteine and monoisoamyl DMSA on tissue oxidative stress during arsenic chelation therapy.
    Biological trace element research, 2006, Volume: 110, Issue:1

    Topics: Acetylcysteine; Animals; Arsenic; Chelation Therapy; Guinea Pigs; Male; Oxidative Stress; Succimer

2006
Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.
    Chemico-biological interactions, 2007, Jan-30, Volume: 165, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Cadmium Chloride; Chelating Agents; Chlorides; Dithiothreitol; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Environmental Pollutants; Enzyme Inhibitors; Lung; Male; Organoselenium Compounds; Porphobilinogen Synthase; Rats; Rats, Wistar; Succimer; Unithiol; Zinc Compounds

2007
In vitro assessment of chelating agents with regard to their abstraction efficiency of Cd(2+) bound to plasma proteins.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:9

    Topics: Acetylcysteine; Animals; Blood Proteins; Cadmium; Calcium; Chelating Agents; Chromatography, Gel; Humans; Rabbits; Spectrophotometry, Atomic; Succimer; Unithiol; Zinc

2012
N-acetylcysteine and meso-2,3-dimercaptosuccinic acid alleviate oxidative stress and hepatic dysfunction induced by sodium arsenite in male rats.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Acetylcysteine; Animals; Arsenites; Chemical and Drug Induced Liver Injury; Male; Oxidative Stress; Rats; Rats, Wistar; Sodium Compounds; Succimer

2016
The examination of the nephroprotective effect of montelukast sodium and N-acetylcysteine ın renal ıschemia with dimercaptosuccinic acid imaging in a placebo-controlled rat model.
    Acta cirurgica brasileira, 2020, Volume: 35, Issue:9

    Topics: Acetates; Acetylcysteine; Animals; Cyclopropanes; Kidney; Quinolines; Rats; Rats, Wistar; Reperfusion Injury; Succimer; Sulfides; Tomography, X-Ray Computed

2020
Characteristics, Treatment, and Prognosis of Elemental Mercury Intoxication in Children: A Single-Center Retrospective Study.
    Pediatric emergency care, 2022, Oct-01, Volume: 38, Issue:10

    Topics: Acetylcysteine; Child; Humans; Mercury; Mercury Poisoning; Penicillamine; Prognosis; Retrospective Studies; Succimer; Sulfonic Acids

2022