acetylcysteine has been researched along with spironolactone in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kachru, DN; Khandelwal, S; Tandon, SK | 1 |
| Coimbra, TM; de Araujo, M; Menezes, LF; Seguro, AC; Shimizu, MH | 1 |
| Bao, Y; Jia, R; Yuan, J | 1 |
| Rudakova, E; Volk, T; Wagner, M | 1 |
| Liu, X; Wang, Q; Xu, R; Yang, J; Zang, M; Zhang, J | 1 |
1 review(s) available for acetylcysteine and spironolactone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
11 other study(ies) available for acetylcysteine and spironolactone
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Chelation in metal intoxication. XXVIII: Effect of thiochelators on mercury (II) toxicity: pre- and post treatment.
Topics: Acetylcysteine; Acrylates; Animals; Chelating Agents; Male; Mercury; Mercury Poisoning; Mercury Radioisotopes; Rats; Rats, Inbred Strains; Spironolactone; Tiopronin | 1988 |
N-acetylcysteine attenuates the progression of chronic renal failure.
Topics: Acetylcysteine; Aldosterone; Animals; Antioxidants; Drug Therapy, Combination; Glomerular Filtration Rate; Kidney Failure, Chronic; Lipid Peroxidation; Male; Mineralocorticoid Receptor Antagonists; Nephrectomy; Rats; Rats, Wistar; Spironolactone | 2005 |
Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells.
Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antibodies; Cells, Cultured; Dose-Response Relationship, Drug; Mesangial Cells; Neutralization Tests; Plasminogen Activator Inhibitor 1; Rats; Reactive Oxygen Species; RNA, Messenger; Spironolactone; Time Factors; Transforming Growth Factor beta1; Up-Regulation | 2007 |
Aldosterone-induced changes in the cardiac L-type Ca(2+) current can be prevented by antioxidants in vitro and are absent in rats on low salt diet.
Topics: Acetylcysteine; Action Potentials; Aldosterone; Animals; Antioxidants; Calcium Channels, L-Type; Corticosterone; Diet, Sodium-Restricted; Electrocardiography; Heart Rate; Heart Ventricles; Kinetics; Male; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Oxidation-Reduction; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Spironolactone; Time Factors | 2008 |
Changes in pharmacokinetic profiles of acetaminophen and its glucuronide after pretreatment with combinations of N-acetylcysteine and either glycyrrhizin, silibinin or spironolactone in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Glycyrrhizic Acid; Hepatobiliary Elimination; Injections, Intraperitoneal; Liver; Male; Rats, Sprague-Dawley; Silybin; Silymarin; Spironolactone; Time Factors | 2014 |