Compounds > acetylcysteine

acetylcysteine and sevoflurane

acetylcysteine has been researched along with sevoflurane in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Anders, MW; Baggs, RB; Iyer, RA; Uttamsingh, V1
Jubert, C; Kharasch, ED1
Gul Altuntas, T; Kharasch, ED1
Altuntas, TG; Kharasch, ED; Park, SB1
Chen, S; Fang, X; Jin, Y; Li, H; Wu, S; Xie, G1
Irwin, MG; Li, H; Li, Y; Lin, J; Wang, M; Wang, T; Xia, Z1
Adeyi, OA; Barbas, AS; Echeverri, J; Goldaracena, N; Grant, DR; Kaths, JM; Louis, KS; Selzner, M; Selzner, N; Spetzler, VN1

Trials

1 trial(s) available for acetylcysteine and sevoflurane

ArticleYear
Compound A uptake and metabolism to mercapturic acids and 3,3,3-trifluoro-2-fluoromethoxypropanoic acid during low-flow sevoflurane anesthesia: biomarkers for exposure, risk assessment, and interspecies comparison.
    Anesthesiology, 1999, Volume: 91, Issue:5

    Topics: Acetylation; Acetylcysteine; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cysteine; Elective Surgical Procedures; Ethers; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Hydrocarbons, Fluorinated; Inactivation, Metabolic; Male; Methyl Ethers; Middle Aged; Propionates; Rats; Sevoflurane

1999

Other Studies

8 other study(ies) available for acetylcysteine and sevoflurane

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Fate and toxicity of 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived mercapturates in male, Fischer 344 rats.
    Anesthesiology, 1998, Volume: 89, Issue:5

    Topics: Acetylcysteine; Acyltransferases; Anesthetics, Inhalation; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytosol; Dealkylation; Drug Contamination; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Magnetic Resonance Spectroscopy; Male; Methyl Ethers; Rats; Rats, Inbred F344; Sevoflurane

1998
Biotransformation of L-cysteine S-conjugates and N-acetyl-L-cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human kidney in vitro: interindividual variability in N-acety
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:2

    Topics: Acetylation; Acetylcysteine; Anesthetics, Inhalation; Biotransformation; Cysteine; Ethers; Free Radical Scavengers; Humans; Hydrocarbons, Fluorinated; Kidney; Lyases; Methyl Ethers; Sevoflurane

2002
Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A).
    Chemical research in toxicology, 2004, Volume: 17, Issue:3

    Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Cysteine; Cytochrome P-450 Enzyme System; Ethers; Humans; Hydrocarbons, Fluorinated; Kidney; Methyl Ethers; Microsomes, Liver; Oxidation-Reduction; Rats; Sevoflurane; Sulfoxides

2004
Sevoflurane combined with ATP activates caspase-1 and triggers caspase-1-dependent pyroptosis in murine J774 macrophages.
    Inflammation, 2013, Volume: 36, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Caspase 1; Caspase Inhibitors; Cell Death; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Inflammation; Macrophages; Methyl Ethers; Mice; Onium Compounds; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Sevoflurane

2013
N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Acetylcysteine; Adiponectin; Animals; Antioxidants; CD36 Antigens; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Male; Methyl Ethers; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nerve Tissue Proteins; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Sevoflurane; STAT3 Transcription Factor; Time Factors; Troponin I

2016
Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2016, Volume: 22, Issue:11

    Topics: Acetylcysteine; Allografts; Alprostadil; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Biliary Tract; Bilirubin; Cold Ischemia; Cytokines; Endothelial Cells; Hyaluronic Acid; Inflammation Mediators; Liver; Liver Transplantation; Male; Methyl Ethers; Models, Animal; Organ Preservation; Perfusion; Reperfusion Injury; Sevoflurane; Sus scrofa; Swine; Temperature; Tissue and Organ Harvesting

2016