acetylcysteine and serine

acetylcysteine has been researched along with serine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's6 (15.79)18.2507
2000's19 (50.00)29.6817
2010's9 (23.68)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Chong, S; Fung, HL; Hough, K; Kakemi, M; Kowaluk, E1
Boomsma, F; Man in 't Veld, AJ; Schalekamp, MA; van der Hoorn, FA1
Deprun, C; Lamthanh, H; Ménez, A; Roumestand, C1
Barreto, JC; Miller, TA; Smith, GS; Tornwall, MS1
Anderson, MT; Ela, SW; Herzenberg, LA; Raju, PA; Roederer, M; Staal, FJ1
Aalbers, T; Commandeur, JN; de Rooij, BM; Groot, EJ; Hommes, JW; Vermeulen, NP1
Aarsman, CJ; Sprong, RC; van Asbeck, BS; van der Bruggen, T; van Oirschot, JF; Winkelhuyzen-Janssen, AM1
Nakagawa, K; Tamai, K; Taya, Y; Yamaizumi, M1
Haruta, T; Iwata, M; Kawahara, J; Kobayashi, M; Takano, A; Uno, T; Usui, I1
Weber, AL1
Anestis, DK; Ball, JG; Brown, PI; Henderson, TT; Hong, SK; Rankin, GO; Valentovic, MA1
Neeman, I; Resnick, N; Schubert, SY1
Faivre, E; Horwitz, KB; Lange, CA; Olsen, A; Qiu, M1
Griendling, KK; Rocic, P; Seshiah, P1
Caltagirone, A; Chahine, D; Fillebeen, C; Pantopoulos, K; Segal, P1
Lee, JR1
Rey, O; Rozengurt, E; Waldron, RT; Zhukova, E1
Huang, J; Hupfeld, CJ; Imamura, T; Lefkowitz, RJ; Olefsky, JM; Satoh, H; Shenoy, SK; Usui, I1
Douglas, P; Kurz, EU; Lees-Miller, SP1
Cao, D; Grdina, DJ; Kataoka, Y; Li, JJ; Murley, JS; Oberley, LW1
Hu, Z; Lelli, KM; Maines, MD; Miralem, T; Torno, MD1
Bauer, NN; Erickson, PF; Fankell, D; Garat, CV; Klemm, DJ; McMurtry, IF; Reusch, JE1
Kobayashi, H; Maruta, T; Nemoto, T; Satoh, S; Sugano, T; Wada, A; Yanagita, T; Yokoo, H; Yoshikawa, N1
Dai, W; Darzynkiewicz, Z; Huang, X; Kurose, A; Tanaka, T; Traganos, F1
Inageda, K; Matsuoka, M; Nishitai, G; Suzuki, K1
Cai, W; Chen, X; He, JC; Striker, GE; Vlassara, H; Zhu, L1
Campos, EI; Garate, M; Li, G; Wang, Y; Wong, RP1
Pattenden, G; Rescourio, G1
Gui, Y; Jiang, Y; Li, H; Li, J; Yin, H; Zheng, XL1
Hasegawa, M; Iguchi, Y; Ishigaki, S; Katsuno, M; Niwa, J; Sobue, G; Takagi, S; Tanaka, F1
Barbanel, G; Billard, JM; Dutar, P; Haxaire, C; Kervern, M; Mothet, JP; Potier, B; Sinet, PM; Turpin, FR1
Corkey, BE; Ferrante, T; Haller, JF; Krawczyk, SA; Zoeller, RA1
Chen, MC; Du, JY; Huang, CH; Lee, CF; Lee, YJ; Lin, TH; Shen, HJ; Wang, JH; Wu, YY1
Higa-Nakamine, S; Izumi, S; Kakinohana, M; Maeda, N; Nishi, H; Sugahara, K; Toku, S; Yamamoto, H1
Bartoli, M; Colasanti, M; Gliozzi, M; Harris, MB; Lamoke, F; Maraschi, A; Mazzone, V; Mollace, V; Muscoli, C; Persichini, T; Venema, RC1
Ahmed, A; Gu, J; Gu, Y; Guo, D; Jiang, H; Zhang, Z1
Ali, I; Fang, NZ; Hu, DB; Li, ZS; Xu, LJ1
Adiels, M; Arif, M; Benfeitas, R; Bergh, PO; Bidkhori, G; Bjornson, E; Borén, J; Bosley, J; Juszczak, K; Kim, JT; Kim, W; Lovric, A; Mardinoglu, A; Marschall, HU; Nielsen, J; Ozcan, M; Ståhlman, M; Taskinen, MR; Tebani, A; Turkez, H; Uhlén, M; Zhang, C1

Other Studies

38 other study(ies) available for acetylcysteine and serine

ArticleYear
Mechanisms for the pharmacologic interaction of organic nitrates with thiols. Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Acetylcysteine; Animals; Aorta; Blood Pressure; Glutathione; Humans; In Vitro Techniques; Male; Metabolic Clearance Rate; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Serine; Vasodilation

1988
Determination of D,L-threo-3,4-dihydroxyphenylserine and of the D- and L-enantiomers in human plasma and urine.
    Journal of chromatography, 1988, Jun-03, Volume: 427, Issue:2

    Topics: Acetylcysteine; Droxidopa; Humans; o-Phthalaldehyde; Serine; Spectrometry, Fluorescence; Stereoisomerism

1988
Side reaction during the deprotection of (S-acetamidomethyl)cysteine in a peptide with a high serine and threonine content.
    International journal of peptide and protein research, 1993, Volume: 41, Issue:1

    Topics: Acetylcysteine; Amino Acid Sequence; Animals; Chemistry, Organic; Cobra Neurotoxin Proteins; Cystine; Ferricyanides; Fluoroacetates; Iodine; Mercury; Molecular Sequence Data; Peptide Fragments; Serine; Snakes; Thallium; Threonine; Trifluoroacetic Acid

1993
Protective action of oral N-acetylcysteine against gastric injury: role of hypertonic sodium.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: Acetylcysteine; Administration, Oral; Animals; Female; Gastric Mucosa; Hypertonic Solutions; Rats; Rats, Sprague-Dawley; Serine; Sodium; Stomach Diseases; Stomach Ulcer

1993
Antioxidants inhibit stimulation of HIV transcription.
    AIDS research and human retroviruses, 1993, Volume: 9, Issue:4

    Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Gene Expression Regulation, Viral; Glutathione; HIV; HIV Long Terminal Repeat; Humans; NF-kappa B; Serine; Transcription, Genetic; Virus Replication

1993
Urinary metabolite profile of phenyl and o-cresyl glycidyl ether in rats: identification of a novel pathway leading to N-acetylserine O-conjugates.
    Chemical research in toxicology, 1998, Volume: 11, Issue:2

    Topics: Acetylcysteine; Animals; Biomarkers; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Kinetics; Lactic Acid; Male; Occupational Exposure; Rats; Rats, Wistar; Serine; Structure-Activity Relationship

1998
Low-dose N-acetylcysteine protects rats against endotoxin-mediated oxidative stress, but high-dose increases mortality.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:4 Pt 1

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Glutathione; Humans; Hydrogen Peroxide; Infusions, Intravenous; Lipopolysaccharides; Lung; Male; Monocytes; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Serine; Survival Rate; Tumor Necrosis Factor-alpha

1998
Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks.
    Molecular and cellular biology, 1999, Volume: 19, Issue:4

    Topics: Acetylcysteine; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Deoxyribonucleases, Type II Site-Specific; DNA Damage; DNA-Binding Proteins; Heat-Shock Response; Humans; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Proteins; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Xeroderma Pigmentosum

1999
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Molecular and cellular biology, 2001, Volume: 21, Issue:15

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenoviridae; Amino Acids; Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cytosol; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Glucose; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tyrosine

2001
Alanine synthesis from glyceraldehyde and ammonium ion in aqueous solution.
    Journal of molecular evolution, 1985, Volume: 21

    Topics: Acetylcysteine; Alanine; Evolution, Chemical; Evolution, Molecular; Formates; Glyceraldehyde; Glycine; Glycolates; Lactic Acid; Quaternary Ammonium Compounds; Serine; Sulfhydryl Compounds

1985
Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.
    Journal of toxicology and environmental health. Part A, 2002, Apr-12, Volume: 65, Issue:7

    Topics: Acetylcysteine; Alanine; Amino Acids; Animals; Fungicides, Industrial; Injections, Intraperitoneal; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Rats; Rats, Inbred F344; Serine; Serotonin; Succinates; Succinimides

2002
A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:14

    Topics: Acetylcysteine; Animals; Antioxidants; Cattle; Cells, Cultured; Endothelium, Vascular; I-kappa B Proteins; Lythraceae; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Serine; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Wine

2002
Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:4

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Breast Neoplasms; Butadienes; Cell Nucleus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Epidermal Growth Factor; Fatty Acids, Unsaturated; Humans; Ligands; Mitogen-Activated Protein Kinase Kinases; Multienzyme Complexes; Mutation; Nitriles; Phosphorylation; Promegestone; Proteasome Endopeptidase Complex; Receptors, Progesterone; Serine; Transcription, Genetic; Tumor Cells, Cultured

2003
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors

2003
A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation.
    Molecular and cellular biology, 2003, Volume: 23, Issue:19

    Topics: Acetylcysteine; Amino Acid Sequence; Animals; Cell Line; Cysteine Proteinase Inhibitors; Deferoxamine; Humans; Iron; Iron Chelating Agents; Iron Regulatory Protein 1; Leupeptins; Mice; Molecular Sequence Data; Mutation; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine

2003
Reactive oxygen species play roles on B cell surface receptor CD40-mediated proximal and distal signaling events: effects of an antioxidant, N-acetyl-L-cysteine treatment.
    Molecular and cellular biochemistry, 2003, Volume: 252, Issue:1-2

    Topics: Acetylcysteine; Animals; Antioxidants; CD40 Antigens; Cell Line, Tumor; Mass Spectrometry; Mice; Phosphorylation; Reactive Oxygen Species; Receptors, Antigen, B-Cell; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Spectrometry, Fluorescence

2003
Oxidative stress induces protein kinase C-mediated activation loop phosphorylation and nuclear redistribution of protein kinase D.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Acetylcysteine; Amino Acid Substitution; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Enzyme Activation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Protein Kinase C; Recombinant Proteins; Serine; Signal Transduction; Swiss 3T3 Cells; Transfection; Tyrosine

2004
beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.
    Molecular and cellular biology, 2004, Volume: 24, Issue:20

    Topics: Acetylcysteine; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Cells, Cultured; Cysteine Proteinase Inhibitors; Fibroblasts; Humans; Insulin; Insulin Receptor Substrate Proteins; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Receptor, Insulin; RNA, Small Interfering; Serine; Signal Transduction; Ubiquitin

2004
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2004
Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.
    Radiation research, 2004, Volume: 162, Issue:5

    Topics: Acetylcysteine; Amifostine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Cell Line, Tumor; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; I-kappa B Proteins; Mercaptoethylamines; Mesna; Mice; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Plasmids; Protective Agents; Radiation-Protective Agents; Serine; Sulfhydryl Compounds; Superoxide Dismutase; Time Factors; Transfection

2004
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; Arsenites; Biliverdine; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Silencing; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Luciferases; Membrane Glycoproteins; Membrane Proteins; Oligonucleotides; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Phosphorylation; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Retroviridae; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Compounds; Threonine; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha

2005
Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells.
    Molecular and cellular biology, 2006, Volume: 26, Issue:13

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Animals; Becaplermin; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Cysteine Proteinase Inhibitors; Fatty Acids, Unsaturated; Humans; Mutation; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Rats; Recombinant Fusion Proteins; Serine; Signal Transduction; Ubiquitin

2006
Constitutive activity of glycogen synthase kinase-3beta: positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells.
    Brain research, 2006, Sep-19, Volume: 1110, Issue:1

    Topics: Acetylcysteine; Adjuvants, Immunologic; Adrenal Glands; Animals; Blotting, Northern; Cattle; Cells, Cultured; Chromaffin Cells; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycogen Synthase Kinase 3; Indoles; Lactones; Lithium Chloride; Maleimides; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Time Factors

2006
Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status.
    Cell proliferation, 2006, Volume: 39, Issue:4

    Topics: Acetylcysteine; Cell Cycle; Cell Line, Tumor; DNA Damage; DNA Repair; Fluorescent Dyes; Free Radical Scavengers; Histones; Humans; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Serine; Tumor Suppressor Protein p53

2006
Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: involvement of ATM pathway.
    Toxicology and applied pharmacology, 2007, Apr-01, Volume: 220, Issue:1

    Topics: Acetylcysteine; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Butadienes; Catalase; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; DNA-Binding Proteins; Epithelial Cells; Humans; Lung; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vanadates; Wortmannin

2007
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:1

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Antioxidants; Cell Line; Chromones; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glycation End Products, Advanced; Humans; Lysine; Morpholines; Mutation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; RNA, Small Interfering; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxide Dismutase; Transfection

2008
NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b).
    EMBO reports, 2008, Volume: 9, Issue:6

    Topics: Acetylcysteine; Animals; Cell Cycle; Cell Line, Tumor; Cycloheximide; Cysteine Proteinase Inhibitors; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Leupeptins; NAD(P)H Dehydrogenase (Quinone); Nuclear Proteins; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Serine; Tumor Suppressor Proteins; Ultraviolet Rays

2008
A new synthetic approach to (+)-lactacystin based on radical cyclisation of enantiopure alpha-ethynyl substituted serine derivatives to 4-methylenepyrrolidinones.
    Organic & biomolecular chemistry, 2008, Sep-21, Volume: 6, Issue:18

    Topics: Acetylcysteine; Cyclization; Free Radicals; Methylation; Molecular Structure; Pyrrolidinones; Serine; Stereoisomerism

2008
Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells.
    Journal of cellular physiology, 2011, Volume: 226, Issue:7

    Topics: Acetylcysteine; Actins; Animals; Binding Sites; Carotid Artery Injuries; Cells, Cultured; Chromatin Immunoprecipitation; Collagen; Cysteine Proteinase Inhibitors; Disease Models, Animal; DNA Polymerase II; Gels; Gene Expression Regulation; Genotype; Humans; Leupeptins; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Phenotype; Phosphorylation; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Serine; Serum Response Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Vasoconstriction

2011
Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Acetylcysteine; Animals; Benzamides; Cells, Cultured; Cerebral Cortex; Cinnamates; DNA-Binding Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; Green Fluorescent Proteins; Humans; Hydrogen Peroxide; Imidazoles; Indoles; Mice; Mice, Inbred C57BL; Neurons; Oxidants; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Serine; Time Factors; Transfection

2012
Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
    Aging cell, 2012, Volume: 11, Issue:2

    Topics: Acetylcysteine; Aging; Animals; Hippocampus; Lysine; Male; Neuronal Plasticity; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine

2012
Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Adult; Antioxidants; Biphenyl Compounds; Colforsin; Female; Humans; Lipids; Lipolysis; Middle Aged; Obesity; Onium Compounds; Phosphorylation; Primary Cell Culture; Protein Transport; Reactive Oxygen Species; Resveratrol; Serine; Signal Transduction; Sterol Esterase; Stilbenes

2012
Suppression of prolactin signaling by pyrrolidine dithiocarbamate is alleviated by N-acetylcysteine in mammary epithelial cells.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Acetylcysteine; Animals; Caseins; Cattle; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Insulin; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Mammary Glands, Animal; Mice; NF-kappa B; Phosphorylation; Pregnancy; Prolactin; Pyrrolidines; Serine; Signal Transduction; Thiocarbamates

2014
Differential regulation of epidermal growth factor receptor by hydrogen peroxide and flagellin in cultured lung alveolar epithelial cells.
    European journal of pharmacology, 2015, Feb-05, Volume: 748

    Topics: Acetylcysteine; Cell Line; Cell Survival; Enzyme Activation; Epithelial Cells; ErbB Receptors; Flagellin; HSP27 Heat-Shock Proteins; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pulmonary Alveoli; Serine; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation.
    Journal of neuroinflammation, 2015, May-03, Volume: 12

    Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Endothelium, Vascular; Free Radical Scavengers; HSP90 Heat-Shock Proteins; Immunoprecipitation; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Vascular Endothelial Growth Factor A

2015
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension.
    Journal of molecular and cellular cardiology, 2016, Volume: 91

    Topics: Acetophenones; Acetylcysteine; Animals; Apoptosis; Calcium; Calcium Channels, L-Type; Cell Proliferation; Gene Expression Regulation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Metalloporphyrins; Monocrotaline; Myocytes, Smooth Muscle; Organ Culture Techniques; Pentose Phosphate Pathway; Phosphorylation; Primary Cell Culture; Pulmonary Artery; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serine

2016
Effect of potential role of p53 on embryo development arrest induced by H
    In vitro cellular & developmental biology. Animal, 2017, Volume: 53, Issue:4

    Topics: Acetylcysteine; Animals; Benzothiazoles; Cell Cycle; Cell Cycle Checkpoints; Embryo, Mammalian; Embryonic Development; Female; Hydrogen Peroxide; Intracellular Space; Male; Mice; Oxidative Stress; Phosphorylation; Serine; Toluene; Tumor Suppressor Protein p53; Zygote

2017
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
    Molecular systems biology, 2020, Volume: 16, Issue:4

    Topics: Acetylcysteine; Adult; Animals; Carnitine; Dietary Supplements; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Metabolomics; Models, Animal; Niacinamide; Non-alcoholic Fatty Liver Disease; Precision Medicine; Pyridinium Compounds; Rats; Serine

2020