acetylcysteine and pyrazinamide

acetylcysteine has been researched along with pyrazinamide in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's10 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abouelhassan, Y; Bai, F; Burch, GM; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Luesch, H; Nguyen, MT; Norwood, VM; Rolfe, M1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Abouelhassan, Y; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Kim, YS; Luesch, H; Tan, H1
Ramirez, J1
Baniasadi, S; Eftekhari, P; Fahimi, F; Masjedi, MR; Raoufy, MR; Tabarsi, P; Velayati, AA1
Amarapurkar, DN; Gupta, VH; Rai, G; Sasi, P; Singh, M; Wangikar, PP1

Reviews

1 review(s) available for acetylcysteine and pyrazinamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetylcysteine and pyrazinamide

ArticleYear
Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:10

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Free Radical Scavengers; Humans; Isoniazid; Liver; Male; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary

2010

Other Studies

10 other study(ies) available for acetylcysteine and pyrazinamide

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, 04-28, Volume: 59, Issue:8

    Topics: Biofilms; Carbon-13 Magnetic Resonance Spectroscopy; Drug Resistance, Bacterial; Drug Screening Assays, Antitumor; Halogens; HeLa Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenazines; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Halogenation; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenazines

2018
Pulmonary alveolar proteinosis. Treatment in a case complicated by tuberculosis.
    The American review of respiratory disease, 1967, Volume: 95, Issue:3

    Topics: Acetylcysteine; Aminosalicylic Acids; Cycloserine; Ethionamide; Heparin; Humans; Isoniazid; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Pulmonary Alveolar Proteinosis; Pyrazinamide; Radiography, Thoracic; Respiratory Function Tests; Therapeutic Irrigation; Tuberculosis, Pulmonary

1967
Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model.
    Human & experimental toxicology, 2012, Volume: 31, Issue:8

    Topics: Acetylcysteine; Antitubercular Agents; Cell Cycle; Cell Survival; Chemical and Drug Induced Liver Injury; Curcumin; Hep G2 Cells; Humans; Isoniazid; Membrane Potential, Mitochondrial; Protective Agents; Pyrazinamide; Silymarin

2012