acetylcysteine and propofol

acetylcysteine has been researched along with propofol in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's7 (50.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Amer, J; Fibach, E; Reich, S; Shapira, MY; Slavin, S; Weiss, L1
Cekic, B; Coskun, I; Eroglu, A; Erturk, E; Geze, S; Karahan, C; Kerimoglu, S; Kosucu, M; Mentese, A; Ulusoy, H1
Bulbuloglu, E; Ciralik, H; Coskuner, I; Goksu, M; Kale, IT; Kantarceken, B; Kurutas, EB; Senoglu, N; Silay, E; Yildiz, H; Yormaz, S; Yuzbasioglu, MF1
Gan, X; Hei, Z; Irwin, MG; Li, H; Li, S; Luo, C; Su, G; Xia, Z; Xing, D1
Hsu, SS; Jan, CR; Liang, WZ1
Albillos-Blanco, M; Burgueño Gómez, B; Carbajo López, A; Chavarría, C; de Benito Sanz, M; Fuentes-Valenzuela, E; García-Alonso, FJ; Miguel Peña, A; Pérez-Arenas, E; Salvador de Las Heras, A; Sánchez-Ocaña, R; Tejedor-Tejada, J1

Reviews

1 review(s) available for acetylcysteine and propofol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetylcysteine and propofol

ArticleYear
Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Blood Gas Analysis; Double-Blind Method; Female; Humans; Lactic Acid; Male; Malondialdehyde; Middle Aged; Propofol; Prospective Studies; Reperfusion Injury; Tourniquets; Treatment Outcome; Young Adult

2009

Other Studies

12 other study(ies) available for acetylcysteine and propofol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
The oxidative status of blood cells in a murine model of graft-versus-host disease.
    Annals of hematology, 2007, Volume: 86, Issue:10

    Topics: Acetylcysteine; Animals; Blood Cells; Cells, Cultured; Disease Models, Animal; Female; Flow Cytometry; Free Radical Scavengers; Graft vs Host Disease; Humans; Hypnotics and Sedatives; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Propofol; Reactive Oxygen Species; Spleen; Tocopherols; Transplantation, Homologous; Transplantation, Isogeneic; Vitamin E; Whole-Body Irradiation

2007
The comparison of the effects of hepatic regeneration after partial hepatectomy, silybum marinaum, propofol, N-acetylcysteine and vitamin E on liver.
    Bratislavske lekarske listy, 2012, Volume: 113, Issue:3

    Topics: Acetylcysteine; Anesthetics, Intravenous; Animals; Antioxidants; Free Radical Scavengers; Hepatectomy; Liver; Liver Regeneration; Male; Plant Preparations; Propofol; Rats; Rats, Wistar; Silybum marianum; Vitamin E

2012
Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Acetylcysteine; Animals; Antioxidants; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Line; Cell Survival; Female; Hydrogen Peroxide; Intestinal Mucosa; Mast Cells; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; p-Methoxy-N-methylphenethylamine; Propofol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tryptases; Up-Regulation

2015
Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes.
    Environmental toxicology, 2017, Volume: 32, Issue:12

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Astrocytes; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Glioblastoma; Humans; Propofol; Rats; Reactive Oxygen Species

2017
Prospective cohort study to evaluate premedication with simethicone and n-acetilcysteine for upper diagnostic gastrointestinal endoscopy.
    Revista espanola de enfermedades digestivas, 2023, Volume: 115, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Endoscopy, Gastrointestinal; Female; Humans; Middle Aged; Premedication; Propofol; Prospective Studies; Simethicone

2023