acetylcysteine and piperidines

acetylcysteine has been researched along with piperidines in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's1 (4.00)18.2507
2000's5 (20.00)29.6817
2010's16 (64.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Bloomer, WD; Lewis, FS; Rutman, RJ1
Funato, H; Kohsaka, S; Mochizuki, H; Shimojo, M; Takasugi, K; Yamamoto, I1
Bassirat, M; Khalil, Z1
Park, DS; Rideout, HJ; Stefanis, L; Wang, Q1
Miller, JM; Ohinata, Y; Schacht, J1
Giri, S; Gonzalez, FJ; Idle, JR; Krausz, KW1
Eliashar, R; Hirshoren, N1
Kawakami, T; Kirita, T; Morisugi, T; Tanaka, Y1
Haskó, G; Liaudet, L; Mackie, K; Mukhopadhyay, P; Pacher, P; Rajesh, M1
Cheng, WH; Lartey, FM; Qi, Y; Schoene, NW1
Green, KN; Hendrix, C; LaFerla, FM; Parachikova, A1
Di Maio, R; Greenamyre, JT; Hu, X; Mastroberardino, PG; Montero, LM1
Doucette, CD; Hoskin, DW; Walsh, M; Yaffe, PB1
Balaji, SN; Trivedi, V1
Akelma, FK; Aydın, GB; Ergil, J; Polat, R; Sayın, M1
Liu, K; Lu, W; Wang, W; Zhang, Y1
Bao, Y; Fan, Q; Ha, L; Ju, X; Li, J; Li, K; Qian, Y; Shang, H; Sun, X; Wang, Q; Zhang, S; Zou, L1
Boß, M; Brüne, B; Dehne, N; Fleming, I; Namgaladze, D; Snodgrass, RG; Weigert, A; Zezina, E1
Feng, Y; Jin, W; Li, H; Pan, H; Zhao, T; Zhao, Y1
Gu, X; Liu, Y; Ma, Z; Ni, Y; Sun, YE; Zhang, W1
Chao, X; Ding, WX; Du, K; Jaeschke, AH; Jaeschke, H; Ramachandran, A; Weemhoff, JL; Woolbright, BL1
Balhara, A; Deshpande, AY; Giri, S; Ladumor, MK; Patil, A; Pokharkar, S; Praneetha, P; Preethi, J; Singh, DK; Singh, S1
Guo, X; Han, L; Jia, Y; Li, W; Peng, Y; Zhang, Z; Zhao, Y; Zheng, J1
Chang, HW; Chen, PH; Huang, MY; Su, YC; Tang, JY; Wang, HR; Yen, CY1
Chen, YT; Hsu, YL; Hung, CH; Liao, WT; Lin, YC; Tsai, MK; Tsai, ML; Tsai, YG1

Reviews

1 review(s) available for acetylcysteine and piperidines

ArticleYear
Wound-healing modulation in upper airway stenosis-Myths and facts.
    Head & neck, 2009, Volume: 31, Issue:1

    Topics: Acetylcysteine; Aminopropionitrile; Animals; Antimetabolites; Colchicine; Fluorouracil; Humans; Hyperbaric Oxygenation; Laryngostenosis; Mitomycin; Nucleic Acid Synthesis Inhibitors; Piperidines; Protein Synthesis Inhibitors; Quinazolinones; Secondary Prevention; Wound Healing

2009

Trials

1 trial(s) available for acetylcysteine and piperidines

ArticleYear
Comparison of Siccoral® spray, Stomatovis ® gargle, and Strefen ® lozenges on postoperative sore throat.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Flurbiprofen; Humans; Male; Middle Aged; Mouthwashes; Pharmaceutical Solutions; Pharyngitis; Piperidines; Postoperative Complications; Prospective Studies; Remifentanil; Tablets; Treatment Outcome; Young Adult

2014

Other Studies

23 other study(ies) available for acetylcysteine and piperidines

ArticleYear
Bipiperidyl mustard, a new obesifying agent in the mouse.
    Science (New York, N.Y.), 1966, Aug-26, Volume: 153, Issue:3739

    Topics: Acetylcysteine; Adipose Tissue; Animals; Female; Gold; Hypothalamus; Lipid Metabolism; Liver; Mice; Muscles; Myocardium; Organ Size; Piperidines; Skin; Spleen

1966
Neuroprotective action of a novel compound--M50463--in primary cultured neurons.
    Brain research, 1999, Jan-02, Volume: 815, Issue:1

    Topics: Acetylcysteine; Animals; Antihypertensive Agents; Batrachotoxins; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Neurons; Neuroprotective Agents; Neurotoxins; Nicardipine; Nitroprusside; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Thiazoles; Veratrine; Vitamin E

1999
Endothelin and free radicals modulate microvascular responses in streptozotocin-induced diabetic rats.
    Microvascular research, 2000, Volume: 59, Issue:1

    Topics: Acetylcysteine; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelin Receptor Antagonists; Endothelins; Free Radicals; Laser-Doppler Flowmetry; Male; Microcirculation; Nitroprusside; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sciatic Nerve; Skin; Streptozocin; Substance P; Superoxide Dismutase; Vasodilator Agents

2000
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-15, Volume: 23, Issue:4

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Animals; Apoptosis; CDC2-CDC28 Kinases; Cell Cycle; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinases; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Flavonoids; Inclusion Bodies; Multienzyme Complexes; Neurons; Piperidines; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Retinoblastoma Protein; Ubiquitin

2003
Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea.
    Brain research, 2003, Mar-21, Volume: 966, Issue:2

    Topics: Acetylcysteine; Acoustic Stimulation; Animals; Auditory Threshold; Cell Count; Cochlea; Dinoprost; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; F2-Isoprostanes; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Noise; Piperidines; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate

2003
The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases.
    Biochemical pharmacology, 2007, Feb-15, Volume: 73, Issue:4

    Topics: Acetylcysteine; Administration, Oral; Animals; Arecoline; Chromatography, Liquid; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Dogs; Humans; Kinetics; Male; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Molecular Structure; Nipecotic Acids; Oxygenases; Piperidines; Recombinant Proteins; Stereoisomerism; Sulfhydryl Compounds; Urinalysis

2007
Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells.
    Journal of biochemistry, 2010, Volume: 147, Issue:5

    Topics: Acetylcysteine; Animals; Cells, Cultured; Curcumin; Cyclooxygenase 2; Free Radical Scavengers; Gene Expression Regulation; Isoquinolines; Leupeptins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Piperidines; Poly Adenosine Diphosphate Ribose; Pyrrolidines; Rabbits; Stress, Mechanical; Structure-Activity Relationship; Synovial Membrane; Thiocarbamates

2010
Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.
    British journal of pharmacology, 2010, Volume: 160, Issue:3

    Topics: Acetylcysteine; Arachidonic Acids; Cell Death; Cell Line; Coronary Vessels; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Endothelial Cells; Humans; Mitogen-Activated Protein Kinases; Morpholines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction

2010
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
    The Journal of biological chemistry, 2010, Oct-22, Volume: 285, Issue:43

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; DNA Breaks; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Guanosine; Humans; Mismatch Repair Endonuclease PMS2; Morpholines; MutL Protein Homolog 1; Nuclear Proteins; Organoselenium Compounds; Piperidines; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.
    PloS one, 2010, Nov-17, Volume: 5, Issue:11

    Topics: Acetylcysteine; Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ascorbic Acid; Benzodioxoles; Brain; Catechin; Cerebral Cortex; Cognition; Curcumin; Dietary Supplements; Folic Acid; Hippocampus; Humans; Immunoblotting; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Piperidines; Polyunsaturated Alkamides; Thioctic Acid; Vitamin B Complex; Vitamins

2010
Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
    Neurobiology of disease, 2013, Volume: 49

    Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pilocarpine; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Compounds

2013
Piperine impairs cell cycle progression and causes reactive oxygen species-dependent apoptosis in rectal cancer cells.
    Experimental and molecular pathology, 2013, Volume: 94, Issue:1

    Topics: Acetylcysteine; Adenocarcinoma; Alkaloids; Apoptosis; Benzodioxoles; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 Enzyme Inhibitors; Free Radical Scavengers; Humans; Mitochondria; Piperidines; Polyunsaturated Alkamides; Reactive Oxygen Species; Rectal Neoplasms; Succinate Dehydrogenase

2013
Suicidal inactivation of methemoglobin by generation of thiyl radical: insight into NAC mediated protection in RBC.
    Current molecular medicine, 2013, Volume: 13, Issue:6

    Topics: Acetylcysteine; Cytoprotection; Erythrocytes; Free Radicals; Heme; Hemolysis; Humans; Hydrogen Peroxide; Kinetics; Methemoglobin; Oxidation-Reduction; Oxidative Stress; Peroxidase; Piperidines; Protective Agents; Spectrometry, Mass, Electrospray Ionization

2013
Mitochondrial reactive oxygen species regulate adipocyte differentiation of mesenchymal stem cells in hematopoietic stress induced by arabinosylcytosine.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Acetylcysteine; Adipocytes; Adipogenesis; Animals; Antioxidants; Cytarabine; Hematopoiesis; Humans; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mitochondria; Organophosphorus Compounds; Oxidative Stress; Piperidines; Reactive Oxygen Species

2015
BA-j as a novel CDK1 inhibitor selectively induces apoptosis in cancer cells by regulating ROS.
    Scientific reports, 2015, Sep-02, Volume: 5

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Fas Ligand Protein; Flavones; Humans; Inhibitory Concentration 50; Macaca; Metabolic Networks and Pathways; Piperidines; Protein Kinase Inhibitors; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2015
Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages.
    The Journal of biological chemistry, 2016, Jan-01, Volume: 291, Issue:1

    Topics: Acetylcysteine; Adipocytes; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cells, Cultured; Culture Media, Conditioned; Cytokines; Dual-Specificity Phosphatases; Endoplasmic Reticulum Stress; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Inflammation Mediators; Macrophages; Mice, Inbred C57BL; Mitochondria; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; NF-kappa B; Organophosphorus Compounds; Oxygen; Palmitates; Phosphorylation; Piperidines; Reactive Oxygen Species; Signal Transduction

2016
Rosbin, a synthetic small molecule, induces A549 cells apoptosis through a ROS-mediated pathway.
    Cell biology international, 2017, Volume: 41, Issue:2

    Topics: A549 Cells; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Caspase 9; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Mitochondria; Piperidines; Reactive Oxygen Species; Thiophenes

2017
N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia.
    Oncotarget, 2017, Mar-07, Volume: 8, Issue:10

    Topics: Acetylcysteine; Analgesics, Opioid; Animals; Blotting, Western; Enzyme Activation; Free Radical Scavengers; Ganglia, Spinal; Hyperalgesia; Infusions, Subcutaneous; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Pain Measurement; Phosphorylation; Piperidines; Postoperative Period; Protein Kinase C; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil

2017
Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity.
    Archives of toxicology, 2019, Volume: 93, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Hepatocytes; Male; Mice, Inbred C57BL; Necrosis; Organophosphorus Compounds; Piperidines; Receptor-Interacting Protein Serine-Threonine Kinases

2019
Characterization of stable and reactive metabolites of piperine formed on incubation with human liver microsomes.
    Journal of mass spectrometry : JMS, 2019, Volume: 54, Issue:9

    Topics: Acetylcysteine; Alkaloids; Benzodioxoles; Chromatography, High Pressure Liquid; Glutathione; Humans; Isomerism; Microsomes, Liver; Piperidines; Polyunsaturated Alkamides; Tandem Mass Spectrometry

2019
Metabolic Activation of Tofacitinib Mediated by Myeloperoxidase
    Chemical research in toxicology, 2019, 12-16, Volume: 32, Issue:12

    Topics: Acetylcysteine; Activation, Metabolic; Animals; Antirheumatic Agents; Hypochlorous Acid; Leukocytes; Leukopenia; Peroxidase; Piperidines; Pyrimidines; Pyrroles; Rats, Sprague-Dawley

2019
Manoalide Shows Mutual Interaction between Cellular and Mitochondrial Reactive Species with Apoptosis in Oral Cancer Cells.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Survival; Ethidium; Fluoresceins; Humans; Mitochondria; Mouth Neoplasms; Oligopeptides; Organophosphorus Compounds; Phenanthridines; Piperidines; Reactive Oxygen Species; Terpenes

2021
IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy.
    International journal of molecular sciences, 2021, Dec-21, Volume: 23, Issue:1

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Antimycin A; Ascorbic Acid; Cell Polarity; Flow Cytometry; Humans; Interleukin-17; Macrophages; Microscopy, Confocal; Mitochondria; Mitophagy; Monocytes; Organophosphorus Compounds; Phosphorylation; Piperidines; Reactive Oxygen Species; THP-1 Cells

2021