acetylcysteine and phenethyl isothiocyanate

acetylcysteine has been researched along with phenethyl isothiocyanate in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (19.23)18.2507
2000's11 (42.31)29.6817
2010's10 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gajda, T; Grzywa, R; Oleksyszyn, J; Psurski, M; Rudnicka, A; Wietrzyk, J; Winiarski, Ł1
Khoury, MD; Pereira, MA1
Choi, CI; Chung, FL; Jiao, D; Kelloff, G; Pittman, B; Rigotty, J; Rivenson, A; Steele, V; Zang, E1
Chung, FL; Conaway, CC; Jiao, D; Koehl, W; Wang, MH; Yang, CS1
Eto, I; Grubbs, CJ; Juliana, MM; Kelloff, GJ; Lubet, RA; Steele, VE1
Espiritu, I; Willits, NH; Witschi, H; Yu, M1
Faulkner, K; Mithen, R; Rose, P; Williamson, G1
Amin, S; Chiao, JW; Chung, FL; Conaway, CC; Dai, W; Reinhardt, J; Wang, CX; Whysner, J; Yang, YM1
Espiritu, I; Pinkerton, KE; Suffia, M; Witschi, H1
Hopkins, RG; Loo, G; Powolny, A; Takahashi, K1
Chiao, JW; Chung, FL; Conaway, CC; Liu, D; Ramaswamy, G; Wang, L; Wu, H1
Johnson, CS; Singh, SV; Trump, DL; Xiao, D1
Lin, CC; Ng, LT; Wu, SJ1
Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM1
Li, G; Song, L; Tang, L; Zhang, Y1
Hwang, ES; Lee, HJ2
Gong, A; He, M; Karnes, RJ; Krishna Vanaja, D; Yin, P; Young, CY1
Balansky, R; De Flora, S; Ganchev, G; Iltcheva, M; Steele, VE1
Calin, GA; Cartiglia, C; Croce, CM; De Flora, S; Izzotti, A; Longobardi, M; Steele, VE1
Li, Y; Liu, B; Wu, X; Xu, K; Yan, H; Zhou, Q; Zhu, Y1
Li, Y; Liu, B; Wu, H; Wu, X; Xu, K; Yan, H; Zhou, Q; Zhu, Y1
Kukongviriyapan, U; Kukongviriyapan, V; Prawan, A; Senggunprai, L; Tusskorn, O1
Fenoglio, D; Filaci, G; Izzotti, A; Lee, JL; Parodi, A; Pulliero, A; Romani, M; Sinkam, PN; Soares, CP; Wu, Y1
Deng, YT; Hsieh, YP; Ko, HH; Kuo, MY; Wu, KJ; Yeh, CC1
Higuchi, Y; Honma, Y; Kasukabe, T; Kato, N; Kumakura, S; Okabe-Kado, J1

Other Studies

26 other study(ies) available for acetylcysteine and phenethyl isothiocyanate

ArticleYear
Synthesis and biological activity of diisothiocyanate-derived mercapturic acids.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Humans; Isothiocyanates

2016
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
    Cancer letters, 1991, Dec-09, Volume: 61, Issue:1

    Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Eflornithine; Ellagic Acid; Isothiocyanates; Male; Precancerous Conditions; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfides; Thiazoles; Thiazolidines; Thiocyanates

1991
Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats.
    Cancer research, 1996, Feb-15, Volume: 56, Issue:4

    Topics: Acetylcysteine; Analysis of Variance; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Chi-Square Distribution; Diet; Free Radical Scavengers; Incidence; Isothiocyanates; Leukemia, Experimental; Leydig Cell Tumor; Lung Neoplasms; Lymphoma; Male; Nicotiana; Nitrosamines; Pancreatic Neoplasms; Plants, Toxic; Rats; Rats, Inbred F344; Survival Rate; Testicular Neoplasms

1996
Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N-acetyl-L-cysteine conjugates.
    Chemical research in toxicology, 1996, Volume: 9, Issue:6

    Topics: Acetylcysteine; Animals; Cysteine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Glutathione; Humans; In Vitro Techniques; Isothiocyanates; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred F344

1996
Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model.
    International journal of cancer, 1997, Jul-03, Volume: 72, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Anethole Trithione; Animals; Anticarcinogenic Agents; Body Weight; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Miconazole; Rats; Rats, Sprague-Dawley; Time Factors

1997
The effects of phenethyl isothiocyanate, N-acetylcysteine and green tea on tobacco smoke-induced lung tumors in strain A/J mice.
    Carcinogenesis, 1998, Volume: 19, Issue:10

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Female; Isothiocyanates; Lung Neoplasms; Male; Mice; Nicotiana; Plants, Toxic; Smoke; Tea

1998
7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes.
    Carcinogenesis, 2000, Volume: 21, Issue:11

    Topics: Acetylcysteine; Animals; Brassicaceae; Chromatography, Liquid; Enzyme Induction; Glucosinolates; Humans; Isothiocyanates; Liver Neoplasms, Experimental; Male; Mass Spectrometry; Mice; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Vegetables

2000
Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 a
    Cancer research, 2002, Jan-01, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Benzo(a)pyrene; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Isothiocyanates; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription Factor AP-1; Tumor Suppressor Protein p53

2002
Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents.
    Carcinogenesis, 2002, Volume: 23, Issue:2

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Aspirin; Blotting, Western; Cell Nucleus; Cyclin D1; Cyclin D2; Cyclins; Cyclohexenes; Dexamethasone; Free Radical Scavengers; Immunohistochemistry; Inositol; Isothiocyanates; Limonene; Lung; Lung Neoplasms; Male; Mice; Nicotiana; Organoselenium Compounds; Tea; Terpenes; Time Factors

2002
Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells.
    Journal of cellular biochemistry, 2003, Dec-15, Volume: 90, Issue:6

    Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Antigens, Differentiation; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Size; Colonic Neoplasms; Dactinomycin; DNA Damage; GADD45 Proteins; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Protein Phosphatase 1; Proteins; RNA, Messenger; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Tumor Suppressor Protein p53

2003
Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Flow Cytometry; G1 Phase; Humans; Isothiocyanates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Neoplasm Transplantation; Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; S Phase; Time Factors; Tumor Suppressor Proteins; Up-Regulation; Vegetables

2004
Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:5

    Topics: Acetylcysteine; Anticarcinogenic Agents; Apoptosis; bcl-X Protein; Caspases; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine Proteinase Inhibitors; G2 Phase; Gene Expression Regulation; Humans; Isothiocyanates; Male; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Transfection

2004
Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; fas Receptor; Flow Cytometry; Humans; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Liver Neoplasms; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Oligopeptides; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Up-Regulation; Vitamin E; X-Linked Inhibitor of Apoptosis Protein

2005
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
    Cancer research, 2005, Sep-15, Volume: 65, Issue:18

    Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinogens; Caspase 3; Caspases; Cell Growth Processes; Disease Progression; Female; In Situ Nick-End Labeling; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Smoking; Sulfoxides; Thiocyanates

2005
The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
    Anti-cancer drugs, 2006, Volume: 17, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Sulfoxides; Thiocyanates; Urinary Bladder Neoplasms

2006
Phenylethyl isothiocyanate and its N-acetylcysteine conjugate suppress the metastasis of SK-Hep1 human hepatoma cells.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:12

    Topics: Acetylcysteine; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Drug Screening Assays, Antitumor; Humans; Isothiocyanates; Liver Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured

2006
Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:7

    Topics: Acetylcysteine; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Cell Proliferation; G2 Phase; Humans; Interleukin-6; Isothiocyanates; Janus Kinase 2; Male; Phosphorylation; Prostatic Neoplasms; Receptors, Androgen; STAT3 Transcription Factor

2009
Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine.
    International journal of cancer, 2010, Mar-01, Volume: 126, Issue:5

    Topics: Acetylcysteine; Animals; Animals, Newborn; Anticarcinogenic Agents; Budesonide; Disease Models, Animal; Female; Isothiocyanates; Lung Neoplasms; Male; Mice; Tobacco Smoke Pollution

2010
Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:1

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Chemoprevention; Cluster Analysis; Enzyme Inhibitors; Gene Expression; Indoles; Isothiocyanates; Lung; Male; MicroRNAs; Oligonucleotide Array Sequence Analysis; Principal Component Analysis; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thiones; Thiophenes; Tobacco Smoke Pollution

2010
Effects of phenylethyl isothiocyanate and its metabolite on cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells.
    International journal of food sciences and nutrition, 2010, Volume: 61, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Brassicaceae; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Glucosinolates; Humans; Isothiocyanates; Male; Phytotherapy; Plant Extracts; Prostatic Neoplasms

2010
Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.
    BMC cancer, 2010, Jun-09, Volume: 10

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Humans; Inhibitory Concentration 50; Isothiocyanates; Lung Neoplasms; Matrix Metalloproteinase 2; Neoplasm Invasiveness; NF-kappa B; Nuclear Proteins; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transfection; Twist-Related Protein 1

2010
Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
    The British journal of nutrition, 2011, Volume: 106, Issue:12

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin B1; Gene Expression; Humans; Isothiocyanates; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Metastasis; Transcription Factor AP-1

2011
Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells.
    BMC cancer, 2013, Dec-05, Volume: 13

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Calcium Signaling; Caspases; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Drug Screening Assays, Antitumor; Enzyme Activation; Glutathione; Humans; Inhibitory Concentration 50; Isothiocyanates; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Reactive Oxygen Species

2013
Nanoparticles increase the efficacy of cancer chemopreventive agents in cells exposed to cigarette smoke condensate.
    Carcinogenesis, 2015, Volume: 36, Issue:3

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Bronchial Neoplasms; Cell Line, Tumor; Humans; Isothiocyanates; Mice, Inbred Strains; Nanoparticles; Resveratrol; Smoking; Stilbenes; Tobacco Smoke Pollution

2015
Phenethyl isothiocyanate enhances TRAIL-induced apoptosis in oral cancer cells and xenografts.
    Clinical oral investigations, 2016, Volume: 20, Issue:9

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Heterografts; Humans; In Situ Nick-End Labeling; Isothiocyanates; Mice; Mouth Neoplasms; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand

2016
Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclohexylamines; Diterpenes; Glycosides; Humans; Isothiocyanates; Pancreatic Neoplasms; Phenylenediamines; Quinolines; Reactive Oxygen Species

2016