acetylcysteine and phenanthrenes

acetylcysteine has been researched along with phenanthrenes in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aihara, M; Araki, T; Dobashi, K; Hamuro, J; Iizuka, K; Mori, M; Murata, Y; Nakazawa, T; Shimizu, Y; Utsugi, M1
BOYLAND, E; SIMS, P2
Hecht, SS; Hochalter, JB; Villalta, PW1
Berg, JZ; Hecht, SS; Hochalter, JB1
Chen, H; Gao, X; Liang, QS; Luo, JL; Wang, ZH; Yang, GT; Yang, L; Zou, XJ1
Lee, WY; Liu, KW; Yeung, JH1
Du, F; Liu, T; Wan, Y; Wang, Y; Xing, J1
Antus, C; Engelmann, P; Gallyas, F; Lorand, T; Priber, JK; Racz, B; Radnai, B; Sumegi, B; Tucsek, Z; Turi, Z; Veres, B1
Hiransai, P; Itharat, A1
Aarts, JM; Ibuki, Y; Shinmen, T; Toyooka, T1
Ahn, JH; Cho, MG; Choi, HS; Lee, JH1
Balbo, S; Cheng, G; Hecht, SS; Upadhyaya, P; Villalta, PW; Zarth, AT1
al'Absi, M; Allen, SS; Benowitz, NL; Carmella, SG; Chen, M; Cinciripini, PM; Denlinger-Apte, R; Donny, EC; Drobes, DJ; Hatsukami, DK; Hecht, SS; Jensen, JA; Koopmeiners, JS; Lane, T; Le, CT; Leischow, S; Luo, K; Luo, X; McClernon, FJ; Murphy, SE; Paiano, V; Robinson, JD; Severson, H; Sipe, C; Strasser, AA; Strayer, LG; Tang, MK; Vandrey, R1

Trials

1 trial(s) available for acetylcysteine and phenanthrenes

ArticleYear
Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.
    JAMA, 2018, 09-04, Volume: 320, Issue:9

    Topics: Acetylcysteine; Adult; Area Under Curve; Biomarkers; Breath Tests; Carbon Monoxide; Creatinine; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Phenanthrenes; Smoke; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Products; Tobacco Use Disorder

2018

Other Studies

13 other study(ies) available for acetylcysteine and phenanthrenes

ArticleYear
Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages.
    Clinical and experimental immunology, 2001, Volume: 124, Issue:2

    Topics: Acetylcysteine; Cell Line; Glutathione; Glutathione Disulfide; Humans; Interferon-gamma; Interleukin-12; Interleukin-4; Lipopolysaccharides; Macrophages, Alveolar; Monocytes; Phenanthrenes

2001
Metabolism of polycyclic compounds. 20. The metabolism of phenanthrene in rabbits and rats: mercapturic acids and related compounds.
    The Biochemical journal, 1962, Volume: 84

    Topics: Acetylcysteine; Animals; Phenanthrenes; Polycyclic Compounds; Rabbits; Rats; Sulfhydryl Compounds

1962
METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS.
    The Biochemical journal, 1965, Volume: 95

    Topics: Acetylcysteine; Animals; Chromatography; Cysteine; Epoxy Compounds; Ethers; Ethers, Cyclic; Glutathione; Metabolism; Phenanthrenes; Polycyclic Compounds; Rabbits; Rats; Research

1965
Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.
    Carcinogenesis, 2008, Volume: 29, Issue:5

    Topics: Acetylcysteine; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Glutathione Transferase; Humans; Inactivation, Metabolic; Models, Molecular; Neoplasms; Phenanthrenes; Polymorphism, Genetic; Spectrometry, Mass, Electrospray Ionization

2008
Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer.
    Chemical research in toxicology, 2009, Mar-16, Volume: 22, Issue:3

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Bay-Region, Polycyclic Aromatic Hydrocarbon; Female; Glutathione; Glutathione Transferase; Hepatocytes; Humans; Male; Metabolic Detoxication, Phase II; Middle Aged; Neoplasms; Phenanthrenes; Polymorphism, Genetic

2009
Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro.
    Experimental & molecular medicine, 2009, Jul-31, Volume: 41, Issue:7

    Topics: Acetylcysteine; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Collagen Type I; Drugs, Chinese Herbal; Fibroblasts; Free Radical Scavengers; In Vitro Techniques; Matrix Metalloproteinase 1; Myocardium; NADPH Oxidases; Oxidative Stress; Phenanthrenes; Rats; Rats, Wistar; Reactive Oxygen Species

2009
Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.
    Cancer letters, 2009, Nov-18, Volume: 285, Issue:1

    Topics: Abietanes; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Furans; Humans; Imidazoles; Inhibitory Concentration 50; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Liver Neoplasms; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Transport; Pyridines; Quinones; Reactive Oxygen Species; Time Factors

2009
Metabolite identification of triptolide by data-dependent accurate mass spectrometric analysis in combination with online hydrogen/deuterium exchange and multiple data-mining techniques.
    Rapid communications in mass spectrometry : RCM, 2011, Oct-30, Volume: 25, Issue:20

    Topics: Acetylcysteine; Animals; Biotransformation; Data Mining; Deuterium Exchange Measurement; Diterpenes; Epoxy Compounds; Mass Spectrometry; Phenanthrenes; Rats; Rats, Wistar

2011
Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
    Molecular cancer, 2012, May-14, Volume: 11

    Topics: Acetylcysteine; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 9; Necrosis; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA Interference; Signal Transduction

2012
Dioscoreanone suppresses LPS-induced nitric oxide production and inflammatory cytokine expression in RAW 264.7 macrophages by NF-κB and ERK1/2 signaling transduction.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:11

    Topics: Acetylcysteine; Animals; Antineoplastic Agents, Phytogenic; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Inhibitory Concentration 50; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Luciferases; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenanthrenes; Quinones

2012
Dual effects of N-acetyl-L-cysteine dependent on NQO1 activity: suppressive or promotive of 9,10-phenanthrenequinone-induced toxicity.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Acetylcysteine; Animals; Cell Line; Cricetinae; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Keratinocytes; NAD(P)H Dehydrogenase (Quinone); Phenanthrenes

2012
DNA double-strand breaks and Aurora B mislocalization induced by exposure of early mitotic cells to H
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Acetylcysteine; Aurora Kinase B; Catalase; Chromatin Assembly and Disassembly; Cytokinesis; DNA Breaks, Double-Stranded; HeLa Cells; Humans; Hydrogen Peroxide; Mitosis; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Protein Transport; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species

2017
Investigation of the presence in human urine of mercapturic acids derived from phenanthrene, a representative polycyclic aromatic hydrocarbon.
    Chemico-biological interactions, 2017, Aug-25, Volume: 274

    Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Glutathione Transferase; Humans; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Stereoisomerism; Tandem Mass Spectrometry

2017