acetylcysteine and pentoxifylline

acetylcysteine has been researched along with pentoxifylline in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (15.15)18.2507
2000's10 (30.30)29.6817
2010's15 (45.45)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Blöhmer, A; Hänel, H; Heidemann, HT; Inselmann, G; Kottny, W; Nellessen, U1
Bernard, GR; Weikert, LF1
Bretschneider, E; Glusa, E; Schrör, K; Weber, AA; Wittpoth, M1
Demir, S; Inal-Erden, M1
Créteur, J; DeBacker, D; Silva, E; Vincent, JL1
Buwalda, M; Ince, C1
Futakuchi, M; Ogawa, K; Shirai, T; Takahashi, S; Tamano, S1
Filipov, NM; Lawrence, DA; Seegal, RF1
Adhikari, N; Burns, KE; Meade, MO1
Eşrefoğlu, M; Gül, M; Turan, F1
Cerqueira, NF; Hussni, CA; Padovani, CR; Sequeira, JL; Yoshida, WB1
Atli, Y; Bulbuloglu, E; Ciralik, H; Dogan, Z; Goksu, M; Kilinc, M; Oksuz, H; Ozkan, OV; Senoglu, N; Yildiz, H; Yuzbasioglu, MF1
Atli, Y; Bulbuloglu, E; Coskuner, I; Deniz, C; Dogan, Z; Kantarçeken, B; Kilinc, M; Oksuz, H; Senoglu, N; Yildiz, H; Yuzbasioglu, MF1
Lucey, MR; Mathurin, P1
Delavari, F; Kadkhodaee, M; Mikaeili, S; Ostad, SN; Seifi, B; Shams, S1
Nikiteas, N; Perrea, D; Tsigris, C; Yiannakopoulou, E1
Seitz, HK; Stickel, F1
Burroughs, AK; Papastergiou, V; Tsochatzis, EA1
Chayanupatkul, M; Liangpunsakul, S1
Atkinson, SR; Bongiorno, CM; Chandar, AK; Loomba, R; Murad, MH; Shah, VH; Singal, AK; Singh, S; Thursz, MR1
Parikh, ND; Schlansky, B1
Li, J; Rana, R; Song, MY; Wang, SL; Xia, L; Yang, CQ1
Donoviel, DB; Jones, JA; McLaughlin, MF1
Agarwal, R; Bhalla, A; Keisham, A; Sharma, N; Sharma, R; Singh, A; Singh, V1
Song, DS1
Ahmadi Kahjoogh, H; Behrangi, E; Goodarzi, A; Hejazi, P; Roohaninasab, M; Yazdanian, N1

Reviews

14 review(s) available for acetylcysteine and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacotherapy of sepsis.
    Clinics in chest medicine, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bradykinin; Cyclooxygenase Inhibitors; Humans; Naloxone; Pentoxifylline; Platelet Activating Factor; Sepsis

1996
Effects of vasoactive drugs on gastric intramucosal pH.
    Critical care medicine, 1998, Volume: 26, Issue:10

    Topics: Acetylcysteine; Cardiotonic Agents; Dobutamine; Dopamine; Epinephrine; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Nitric Oxide; Norepinephrine; Pentoxifylline; Prostaglandins; Research Design; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilator Agents

1998
Opening the microcirculation: can vasodilators be useful in sepsis?
    Intensive care medicine, 2002, Volume: 28, Issue:9

    Topics: Acetylcysteine; Animals; Epoprostenol; Hemodynamics; Humans; Microcirculation; Netherlands; Nitric Oxide Donors; Oxygen; Pentoxifylline; Sepsis; Treatment Outcome; Vasodilator Agents

2002
Pharmacologic treatments for acute respiratory distress syndrome and acute lung injury: systematic review and meta-analysis.
    Treatments in respiratory medicine, 2004, Volume: 3, Issue:5

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alprostadil; Humans; Pentoxifylline; Randomized Controlled Trials as Topic; Respiration, Artificial; Respiratory Distress Syndrome; Surface-Active Agents; Vasodilator Agents

2004
Management of alcoholic hepatitis.
    Journal of hepatology, 2012, Volume: 56 Suppl 1

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcohol Drinking; Enteral Nutrition; Free Radical Scavengers; Hepatitis, Alcoholic; Humans; Liver Transplantation; Pentoxifylline; Prognosis; Severity of Illness Index; Tumor Necrosis Factor-alpha

2012
Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2012, Volume: 22, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Erythromycin; Humans; Laparoscopy; Melatonin; Mesna; Oxidative Stress; Pentoxifylline; Pneumoperitoneum, Artificial; Rabbits; Rats; Verapamil; Zinc Compounds

2012
Update on the management of alcoholic steatohepatitis.
    Journal of gastrointestinal and liver diseases : JGLD, 2013, Volume: 22, Issue:2

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcohol Abstinence; Animals; Enteral Nutrition; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Immunosuppressive Agents; Liver Transplantation; Pentoxifylline; Treatment Outcome

2013
Prognosis and treatment of patients with acute alcoholic hepatitis.
    Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:5

    Topics: Acetylcysteine; Acute Disease; Adrenal Cortex Hormones; Antioxidants; Drug Resistance; Drug Therapy, Combination; Hepatitis, Alcoholic; Hepatorenal Syndrome; Humans; Liver Transplantation; Patient Selection; Pentoxifylline; Phosphodiesterase Inhibitors; Risk Factors; Severity of Illness Index; Treatment Outcome

2014
Alcoholic hepatitis: a comprehensive review of pathogenesis and treatment.
    World journal of gastroenterology, 2014, May-28, Volume: 20, Issue:20

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcoholism; End Stage Liver Disease; Enteral Nutrition; Hepatitis, Alcoholic; Humans; Immunity, Innate; Inflammation; Liver Transplantation; Pentoxifylline; Propylthiouracil; S-Adenosylmethionine; Treatment Outcome

2014
Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis.
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Comparative Effectiveness Research; Disease Progression; Drug Therapy, Combination; Free Radical Scavengers; Hepatitis, Alcoholic; Humans; Pentoxifylline; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2015
A prognostic evaluation and management of alcoholic hepatitis.
    Minerva medica, 2017, Volume: 108, Issue:6

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Alcohol Abstinence; Bilirubin; Biomarkers; Biopsy; Combined Modality Therapy; Creatinine; Drug Substitution; Hepatitis, Alcoholic; Hepatorenal Syndrome; Humans; Liver; Liver Function Tests; Liver Transplantation; Models, Biological; Nutritional Support; Pentoxifylline; Prognosis; Risk Factors; Severity of Illness Index

2017
Novel Indications for Commonly Used Medications as Radiation Protectants in Spaceflight.
    Aerospace medicine and human performance, 2017, Jul-01, Volume: 88, Issue:7

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Aerospace Medicine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Astronauts; Calcium Channel Blockers; Fingolimod Hydrochloride; Free Radical Scavengers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Immunosuppressive Agents; Metformin; Pentoxifylline; Radiation Injuries; Radiation-Protective Agents; Space Flight

2017
[Medical Treatment of Alcoholic Liver Disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2020, 08-25, Volume: 76, Issue:2

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Enteral Nutrition; Fecal Microbiota Transplantation; Granulocyte Colony-Stimulating Factor; Humans; Liver Diseases, Alcoholic; Pentoxifylline; Severity of Illness Index

2020

Trials

2 trial(s) available for acetylcysteine and pentoxifylline

ArticleYear
Efficacy of Granulocyte Colony-Stimulating Factor and N-Acetylcysteine Therapies in Patients With Severe Alcoholic Hepatitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2018, Volume: 16, Issue:10

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Free Radical Scavengers; Granulocyte Colony-Stimulating Factor; Hepatitis, Alcoholic; Humans; Immunologic Factors; India; Liver Function Tests; Male; Middle Aged; Pentoxifylline; Pilot Projects; Prospective Studies; Survival Analysis; Treatment Outcome; Young Adult

2018
Efficacy, safety, tolerability, and satisfaction of N-acetylcysteine and pentoxifylline in lichen planopilaris patients under treatment with topical clobetasol: A triple arm blinded randomized controlled trial.
    Dermatologic therapy, 2022, Volume: 35, Issue:8

    Topics: Acetylcysteine; Administration, Topical; Adult; Clobetasol; Female; Humans; Lichen Planus; Male; Middle Aged; Patient Satisfaction; Pentoxifylline; Personal Satisfaction; Treatment Outcome

2022

Other Studies

17 other study(ies) available for acetylcysteine and pentoxifylline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Modification of cisplatin-induced renal p-aminohippurate uptake alteration and lipid peroxidation by thiols, Ginkgo biloba extract, deferoxamine and torbafylline.
    Nephron, 1995, Volume: 70, Issue:4

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Deferoxamine; Glutathione; In Vitro Techniques; Kidney Cortex; Lipid Peroxidation; Male; p-Aminohippuric Acid; Pentoxifylline; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

1995
Activation of NFkappaB is essential but not sufficient to stimulate mitogenesis of vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1997, Jun-18, Volume: 235, Issue:2

    Topics: Acetylcysteine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Arteries; Blotting, Western; Cattle; Cell Division; Cells, Cultured; Coronary Vessels; Molecular Sequence Data; Muscle, Smooth, Vascular; NF-kappa B; Pentoxifylline; Peptide Fragments; Peptides; Protease Inhibitors; Thrombin; Thymidine; Vasodilator Agents

1997
Pentoxifylline and N-acetylcysteine in hepatic ischemia/reperfusion injury.
    Clinica chimica acta; international journal of clinical chemistry, 1998, Jul-28, Volume: 275, Issue:2

    Topics: Acetylcysteine; Animals; Catalase; Female; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Ischemia; Lipid Peroxidation; Liver; Malondialdehyde; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Vasodilator Agents

1998
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma.
    Cancer science, 2004, Volume: 95, Issue:1

    Topics: Acetylcysteine; Animals; Aspirin; Blotting, Western; Carcinogens; Diethylnitrosamine; E-Selectin; Enzyme Inhibitors; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasm Metastasis; NF-kappa B; Nitrosamines; Pentoxifylline; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Cell Adhesion Molecule-1

2004
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cytokines; Enzyme Inhibitors; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Manganese Poisoning; Mice; Microglia; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pentoxifylline; Phosphodiesterase Inhibitors; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

2005
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; Liver Diseases; Melatonin; Pancreatitis; Pentoxifylline; Rats; Rats, Wistar; Statistics, Nonparametric

2008
Effects of pentoxifylline and n-acetylcysteine on injuries caused by ischemia and reperfusion of splanchnic organs in rats.
    International angiology : a journal of the International Union of Angiology, 2008, Volume: 27, Issue:6

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Hemodynamics; Intestinal Mucosa; Intestine, Small; Male; Mesenteric Vascular Occlusion; Oxidative Stress; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Shock; Splanchnic Circulation; Time Factors

2008
Re-protective effects of pre- and post-laparoscopy conditioning, zinc, pentoxifylline, and N-acetylcysteine in an animal model of laparoscopy-induced ischemia/reperfusion injury of the kidney.
    Renal failure, 2009, Volume: 31, Issue:4

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Kidney; Laparoscopy; Male; Pentoxifylline; Pneumoperitoneum, Artificial; Postoperative Care; Preoperative Care; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Zinc

2009
Protective effects of zinc, pentoxifylline, and N-acetylcysteine in an animal model of laparoscopy-induced ischemia/reperfusion injury of the small intestine.
    Journal of laparoendoscopic & advanced surgical techniques. Part A, 2011, Volume: 21, Issue:10

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Intestine, Small; Laparoscopy; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Zinc

2011
Pretreatment with pentoxifylline and N-acetylcysteine in liver ischemia reperfusion-induced renal injury.
    Renal failure, 2012, Volume: 34, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Liver; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2012
Comparative Effectiveness of Medical Therapies for Severe Alcoholic Hepatitis: Guidance at Last?
    Gastroenterology, 2015, Volume: 149, Issue:4

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Free Radical Scavengers; Hepatitis, Alcoholic; Humans; Pentoxifylline

2015