acetylcysteine has been researched along with pd 98059 in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (10.53) | 18.2507 |
| 2000's | 33 (57.89) | 29.6817 |
| 2010's | 17 (29.82) | 24.3611 |
| 2020's | 1 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Charland, C; Fung, H; Goldberg, J; Janssen, YM; Jiménez, LA; Mossman, BT; Vacek, P; Zanella, C | 1 |
| Khan, M; Namboodiri, AM; Pahan, K; Sheikh, FG; Singh, I | 1 |
| Cunnick, JM; Sekharam, M; Trotti, A; Wu, J | 1 |
| Greene, LA; Yan, CY | 1 |
| Darnell, BF; Grammer, AC; Heaney, J; Lipsky, PE; McFarland, RD | 1 |
| Joe, E; Jou, I; Jung, S; Lee, SH; Pyo, H | 1 |
| Jonakait, GM; Ni, L; Wan, Y; Wen, Y | 1 |
| Gon, Y; Hashimoto, S; Horie, T; Kujime, K; Shimizu, K | 1 |
| Bonner, JC; Wang, YZ | 1 |
| Joe, E; Jou, I; Pyo, H; Ryu, J | 1 |
| Dehnade, F; Li, WQ; Zafarullah, M | 1 |
| Ahn, HJ; Fujiwara, H; Hamaoka, T; Kurimoto, M; Nakahira, M; Ohta, T; Park, CS; Park, WR; Sugimoto, N | 1 |
| Funakoshi, Y; Ichiki, T; Iino, N; Ito, K; Takeda, K; Takeshita, A; Tokunou, T | 1 |
| Grant, S; Vrana, JA | 1 |
| Chen, YC; Lee, WR; Lin, JK; Shen, SC; Tsai, SH | 1 |
| Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T | 2 |
| Inanami, O; Kuwabara, M; Tsuji, M | 1 |
| Hescheler, J; Klimm, B; Sauer, H; Wartenberg, M | 1 |
| Jonakait, GM; Ni, L; Peng, X; Wen, Y | 1 |
| Bhalla, RC; Deleon, J; Gurjar, MV; Sharma, RV | 1 |
| Gafni, M; Keren, O; Sarne, Y; Shapira, M | 1 |
| Bezombes, C; Demur, C; Filomenko, R; Hernandez, H; Jaffrézou, JP; Laurent, G; Maestre, N; Mas, VM; Plo, I; Quillet-Mary, A | 1 |
| Franklin, JL; Kirkland, RA | 1 |
| Fukuda, I; Hatakeyama, M; Imaizumi, T; Matsumiya, T; Munakata, H; Satoh, K; Shibata, T; Tamo, W; Yoshida, H | 1 |
| He, D; Natarajan, V; Parinandi, NL; Usatyuk, PV; Vepa, S; Watkins, T | 1 |
| Chen, SS; Gong, J | 1 |
| Li, L; Renier, G; Sawamura, T | 1 |
| Aoki, Y; Kanai, H; Kawai-Kowase, K; Kurabayashi, M; Maeno, T; Nagai, R; Ohyama, Y; Oyama, Y; Sakamoto, H; Sato, H; Sato, M; Suga, T; Tamura, J | 1 |
| Cheng, YW; Kang, JJ; Lee, CC | 1 |
| Anand-Srivastava, MB; Daou, GB; Lappas, G | 1 |
| Kim, CH; Kwon, TK; Lee, JT; Lee, TJ; Moon, SK; Park, JW | 1 |
| Costanzo, C; Dalla Pozza, E; Donadelli, M; Palmieri, M; Piacentini, P; Scarpa, A; Scupoli, MT | 1 |
| Bark, H; Choi, CH; Chung, JM; Kim, SH; Park, EK | 1 |
| Bang, S; Cho, DH; Hur, DY; Jung, MK; Kim, KE; Kim, T; Park, H; Song, HK | 1 |
| Chen, YC; Lin, CW; Shen, SC; Yang, LY | 1 |
| Cheng, D; Ding, Y; Hu, X; Jiang, F; Wen, F; Yang, D; Ying, B; Zhang, Y; Zhou, C | 1 |
| Chen, CH; Chen, TH; Chen, TW; Chen, YC; Cheng, CY; Hou, CC; Hsu, YH; Lin, SL; Sue, YM | 1 |
| Cheng, ML; Cheng, TH; Chiu, DT; Ho, HY; Lin, CJ; You, TH; Yu, JS | 1 |
| Cao, X; Qin, K; Wang, T; Xu, Y; Zhang, Z | 1 |
| Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yang, SF | 1 |
| Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J | 1 |
| Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B | 1 |
| Chen, YC; Cheng, MC; Chien, CC; Huang, GC; Lin, CT; Shen, SC; Wu, J; Yang, LY | 1 |
| Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yu, CC | 1 |
| Chang, YC; Huang, FM; Lee, SS; Tsai, CH | 1 |
| Radhika, A; Sudhakaran, PR | 1 |
| Chang, YC; Huang, FM; Kuan, YH; Lee, SS; Tsai, CH | 1 |
| Phelan, S; Taparra, K; Tehan, L | 1 |
| Cao, L; Chen, X; Li, W; Ma, Q; Xiao, X | 1 |
| Jang, HS; Lee, SH; Min, YS; Park, SY; Sohn, UD; Um, SI; Whang, WK | 1 |
| Cui, NX; Du, X; Gong, M; Liu, WJ; Wang, Y; Yi, ZC; Yu, CH | 1 |
| Chen, Y; Cheng, J; Li, Z; Shen, Y; Wang, W; Zhang, G | 1 |
| Cui, HX; Du, J; Kang, L; Li, S; Liu, HJ; Wang, L | 1 |
| Liang, N; Liang, Y; Lu, C; Ma, Y; Xiao, F; Zhang, Y | 1 |
| Okada, M; Otani, K; Sagara, A; Yamamoto, A; Yamawaki, H | 1 |
57 other study(ies) available for acetylcysteine and pd 98059
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2.
Topics: Acetylcysteine; Animals; Apoptosis; Asbestos; Asbestos, Crocidolite; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Glutathione Transferase; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Pleura; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Recombinant Fusion Proteins; Signal Transduction | 1997 |
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
Topics: Acetylcysteine; Alkyl and Aryl Transferases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Ceramides; Cytokines; Drug Interactions; Enzyme Induction; Flavonoids; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase Inhibitors; Pyrrolidines; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Thiocarbamates | 1998 |
Suppression of fibroblast cell cycle progression in G1 phase by N-acetylcysteine.
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Death; Cell Division; Cyclin D1; DNA; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Free Radical Scavengers; G1 Phase; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases | 1998 |
Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway.
Topics: Acetylcysteine; Androstadienes; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Survival; Chromones; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression Regulation; Genes, Immediate-Early; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neurons; Nitric Oxide Synthase; PC12 Cells; ras Proteins; Rats; Signal Transduction; Wortmannin | 1998 |
Expression, regulation, and function of B cell-expressed CD154 in germinal centers.
Topics: Acetylcysteine; B-Lymphocyte Subsets; CD40 Antigens; CD40 Ligand; Cell Communication; Cell Count; Cell Separation; Cells, Cultured; Cyclosporine; Flavonoids; Germinal Center; Humans; Immunologic Memory; Immunophenotyping; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Palatine Tonsil; Protein Synthesis Inhibitors; Receptors, Antigen, B-Cell; Up-Regulation | 1999 |
Gangliosides activate cultured rat brain microglia.
Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Brain; Culture Techniques; Cyclooxygenase 2; Enzyme Inhibitors; Flavonoids; Gangliosides; Imidazoles; Isoenzymes; Lipopolysaccharides; MAP Kinase Signaling System; Microglia; Mitogen-Activated Protein Kinases; Neuraminidase; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 1999 |
Macrophage cell-conditioned medium promotes cholinergic differentiation of undifferentiated progenitors and synergizes with nerve growth factor action in the developing basal forebrain.
Topics: Acetylcysteine; Animals; Cell Differentiation; Cells, Cultured; Choline O-Acetyltransferase; Culture Media, Conditioned; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Macrophages; Microglia; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurons; Phenotype; Prosencephalon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Reactive Oxygen Species; Receptors, Cholinergic; RNA, Messenger; Septal Nuclei; Stem Cells | 2000 |
p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells.
Topics: Acetylcysteine; Bronchi; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Line; Chemokine CCL5; Cytokines; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Imidazoles; Indoles; Influenza A virus; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines | 2000 |
Mechanism of extracellular signal-regulated kinase (ERK)-1 and ERK-2 activation by vanadium pentoxide in rat pulmonary myofibroblasts.
Topics: Acetylcysteine; Animals; Asthma; Bronchitis; Carbon; Coal Ash; Colforsin; Enzyme Activation; ErbB Receptors; Fibroblasts; Flavonoids; Intracellular Signaling Peptides and Proteins; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Quinazolines; Rats; Titanium; Tyrphostins; Vanadium Compounds | 2000 |
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B.
Topics: Acetylcysteine; Animals; Carbazoles; Cells, Cultured; Cerebral Cortex; Enzyme Induction; Flavonoids; Imidazoles; Indoles; Maleimides; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Kinase C; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thrombin | 2000 |
Thiol antioxidant, N-acetylcysteine, activates extracellular signal-regulated kinase signaling pathway in articular chondrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Free Radical Scavengers; Glutathione; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates; Time Factors | 2000 |
Differential effects of N-acetyl-l-cysteine on IL-2- vs IL-12-driven proliferation of a T cell clone: implications for distinct signalling pathways.
Topics: Acetylcysteine; Animals; Cell Division; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Imidazoles; Interleukin-12; Interleukin-2; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Precipitin Tests; Pyridines; Recombinant Proteins; Signal Transduction; T-Lymphocytes | 2000 |
Reactive oxygen species-mediated homologous downregulation of angiotensin II type 1 receptor mRNA by angiotensin II.
Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antioxidants; Binding, Competitive; Cells, Cultured; Down-Regulation; Enzyme Activation; Flavonoids; Gene Expression Regulation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transfection | 2001 |
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins | 2001 |
Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.
Topics: Acetylcysteine; Arsenites; Blotting, Northern; Blotting, Western; Colorectal Neoplasms; Curcumin; Cyclooxygenase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Indomethacin; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation.
Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cell Division; Cells, Cultured; DNA; Drug Synergism; Flavonoids; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; Probucol; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Tyrphostins | 2001 |
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
Topics: Acetylcysteine; Androstadienes; Animals; Cyclic N-Oxides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Indoles; Isoquinolines; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurites; Neuroprotective Agents; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Kinase C; ras Proteins; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Wortmannin | 2001 |
Activation of p90RSK and growth stimulation of multicellular tumor spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP.
Topics: Acetylcysteine; Adenosine Triphosphate; Calcium; Cell Division; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Free Radical Scavengers; Humans; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phospholipases A; Phospholipases A2; Phosphorylation; Prostatic Neoplasms; Purinergic Agonists; Reactive Oxygen Species; Receptors, Purinergic; Ribosomal Protein S6 Kinases; Spheroids, Cellular; Thiourea; Tumor Cells, Cultured; Vitamin E | 2001 |
Antioxidants N-acetylcysteine (NAC) and 2-mercaptoethanol (2-ME) affect the survival and differentiative potential of cholinergic precursors from the embryonic septal nuclei and basal forebrain: involvement of ras signaling.
Topics: Acetylcysteine; Animals; Antioxidants; Astrocytes; Cell Differentiation; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Mercaptoethanol; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurites; Neurons; Phosphorylation; ras Proteins; Rats; Septal Nuclei; Signal Transduction; Stem Cells | 2001 |
Role of reactive oxygen species in IL-1 beta-stimulated sustained ERK activation and MMP-9 induction.
Topics: Acetylcysteine; Animals; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; Interleukin-1; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2001 |
Divers pathways mediate delta-opioid receptor down regulation within the same cell.
Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antirheumatic Agents; Chloroquine; Cysteine Proteinase Inhibitors; Diprenorphine; Down-Regulation; Etorphine; Flavonoids; Genistein; GTP-Binding Proteins; Humans; Kidney; MAP Kinase Signaling System; Narcotic Antagonists; Neuroblastoma; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Staurosporine; Teprotide; Transfection; Tritium; Tumor Cells, Cultured | 2001 |
Lysophosphatidylcholine is a major contributor to the synergistic effect of mildly oxidized low-density lipoprotein with endothelin-1 on vascular smooth muscle cell proliferation.
Topics: Acetylcysteine; Aldehydes; Animals; Aorta, Thoracic; Cell Count; Cell Division; Cells, Cultured; DNA; Endothelin Receptor Antagonists; Endothelin-1; Flavonoids; Free Radical Scavengers; Growth Inhibitors; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Oxidants; Peptides, Cyclic; Rabbits; Reactive Oxygen Species | 2002 |
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antioxidants; Bridged-Ring Compounds; Cell Death; Daunorubicin; Diglycerides; Enzyme Activation; Flavonoids; Humans; Leukemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Thiocarbamates; Thiones; Transfection; Tumor Cells, Cultured; Wortmannin | 2003 |
Prooxidant effects of NGF withdrawal and MEK inhibition in sympathetic neurons.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cycloheximide; Fetus; Flavonoids; Glutathione; MAP Kinase Signaling System; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Nerve Growth Factor; Neurons; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superior Cervical Ganglion; Sympathetic Nervous System | 2003 |
Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Topics: Acetylcysteine; Anthracenes; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; I-kappa B Proteins; Imidazoles; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Leupeptins; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Umbilical Veins | 2003 |
Redox regulation of reactive oxygen species-induced p38 MAP kinase activation and barrier dysfunction in lung microvascular endothelial cells.
Topics: Acetylcysteine; Animals; Blotting, Western; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutathione; Hydrogen Peroxide; Imidazoles; Lung; MAP Kinase Signaling System; Microcirculation; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Permeability; Pyridines; Reactive Oxygen Species; Time Factors | 2003 |
Polyphenolic antioxidants inhibit peptide presentation by antigen-presenting cells.
Topics: Acetylcysteine; Animals; Antigen Presentation; Antigen-Presenting Cells; Antigens, CD; Antioxidants; B-Lymphocytes; B7-2 Antigen; Bone Marrow Cells; CD40 Antigens; Chlorogenic Acid; Cysteine Endopeptidases; Down-Regulation; Fibroblasts; Flavonoids; Histocompatibility Antigens Class II; Hybridomas; Interleukin-2; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Mast Cells; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Nuclear Proteins; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Protein Biosynthesis; Proteins; Quercetin; Reactive Oxygen Species; Rutin; Signal Transduction; Spleen; T-Lymphocytes; Tobacco, Smokeless; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor alpha-Induced Protein 3 | 2003 |
Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.
Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; Curcumin; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Flavonoids; Foam Cells; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Macrophages; Male; MAP Kinase Signaling System; Mesylates; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Processing, Post-Translational; Pyrroles; Receptors, LDL; RNA, Messenger; Signal Transduction; Sulfones; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2004 |
c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.
Topics: Acetophenones; Acetylcysteine; Animals; Catalase; Cell Line; Ditiocarb; DNA-Binding Proteins; Fibroblasts; Flavonoids; Fluoresceins; Gene Expression Regulation; Gene Targeting; Hydrogen Peroxide; Mice; Mice, Inbred C3H; Microfilament Proteins; Muscle Proteins; NADPH Oxidases; Naphthalenes; Plasminogen Activator Inhibitor 1; Proto-Oncogene Proteins pp60(c-src); Pyrazoles; Pyrimidines; Recombinant Fusion Proteins; Serum Response Factor; Signal Transduction; Smad3 Protein; Smad4 Protein; Smad6 Protein; src-Family Kinases; Sulfones; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.
Topics: Acetylcysteine; Anthracenes; Cell Line, Tumor; Cell Survival; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Motorcycles; NF-kappa B; Proline; RNA, Messenger; Thiocarbamates; Vehicle Emissions | 2005 |
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Onium Compounds; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Superoxides | 2005 |
Age-related differential growth rate and response to 4-hydroxynonenal in mouse aortic smooth muscle cells.
Topics: Acetylcysteine; Age Factors; Aging; Aldehydes; Animals; Aorta; Cell Cycle; Cell Death; Cell Proliferation; Cells, Cultured; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Growth Inhibitors; MAP Kinase Signaling System; Mice; Myocytes, Smooth Muscle; Reactive Oxygen Species | 2006 |
Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA Primers; Fibroblasts; Flavonoids; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoblotting; Mice; Oligonucleotides, Antisense; Pancreatic Neoplasms; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; Thiocarbamates | 2006 |
Elevated reactive oxygen species but not glutathione regulate mercury resistance to AML-2/DX100 cells.
Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Imidazoles; Mercuric Chloride; Multidrug Resistance-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Probenecid; Pyridines; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates | 2006 |
IL-18 enhances the migration ability of murine melanoma cells through the generation of ROI and the MAPK pathway.
Topics: Acetylcysteine; Animals; Cell Movement; Flavonoids; Free Radical Scavengers; Interleukin-18; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Reactive Oxygen Species; Transfection | 2006 |
IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Anthracenes; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Flavanones; Flavonoids; Glycosides; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Molecular Structure; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Quercetin; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship; Transfection | 2007 |
Mechanical stress upregulates intercellular adhesion molecule-1 in pulmonary epithelial cells.
Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Epithelial Cells; Flavonoids; Humans; Intercellular Adhesion Molecule-1; Pulmonary Alveoli; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical; Time Factors; Up-Regulation | 2008 |
Urotensin II induces transactivation of the epidermal growth factor receptor via transient oxidation of SHP-2 in the rat renal tubular cell line NRK-52E.
Topics: Acetylcysteine; Animals; Cell Line; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Kidney Tubules, Proximal; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Rats; Reactive Oxygen Species; Transcriptional Activation; Urotensins | 2009 |
Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis.
Topics: Acetylcysteine; Anthracenes; Apoptosis; Dual Specificity Phosphatase 1; Flavonoids; Gene Knockdown Techniques; Glucosephosphate Dehydrogenase; Hep G2 Cells; Humans; Hydrogen Peroxide; Imidazoles; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Pyridines | 2010 |
Cell cycle events mediate lactacystin-induced apoptotic death of neuronal PC12 cells.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Mitogen-Activated Protein Kinase 3; Neurons; PC12 Cells; Rats | 2010 |
Hypoxia inducible factor-1α expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Acetylcysteine; Areca; Arecoline; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Line; Cholinergic Agonists; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radical Scavengers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mouth Mucosa; Mouth Neoplasms; Protein Kinase C; Staurosporine; Time Factors; Transcription Factor AP-1 | 2010 |
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells | 2011 |
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells | 2011 |
Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells.
Topics: Acetylcysteine; Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Chromatin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Vitamin K 3 | 2011 |
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Catechin; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Male; Middle Aged; Mouth Neoplasms; Nitrobenzenes; Pyridines; Quercetin; Sulfonamides | 2012 |
Regulation of protease-activated receptor-1 expression in human buccal fibroblasts stimulated with arecoline.
Topics: Acetylcysteine; Arecoline; Blotting, Western; Cell Culture Techniques; Cholinergic Agonists; Chromones; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Immunohistochemistry; Morpholines; Mouth Mucosa; Nitrobenzenes; Oral Submucous Fibrosis; Receptor, PAR-1; Rifabutin; Sulfonamides | 2013 |
Upregulation of macrophage-specific functions by oxidized LDL: lysosomal degradation-dependent and -independent pathways.
Topics: Acetylcysteine; Cell Differentiation; Cells, Cultured; Chloroquine; Chromones; Copper Sulfate; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression; Humans; Imidazoles; Leukocytes, Mononuclear; Lipoproteins, LDL; Lysosomes; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Morpholines; Naphthalenes; NF-kappa B; Oxidation-Reduction; PPAR gamma; Proteolysis; Pyridines; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation | 2013 |
The upregulation of transglutaminase-2 by cyclosporin a in human gingival fibroblasts is augmented by oxidative stress.
Topics: Acetylcysteine; Adult; Antioxidants; Catechin; Cell Culture Techniques; Cells, Cultured; Chromones; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Flavonoids; Free Radical Scavengers; Gingiva; GTP-Binding Proteins; Humans; Imidazoles; Immunosuppressive Agents; Male; Morpholines; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Protease Inhibitors; Protein Glutamine gamma Glutamyltransferase 2; Pyridines; Reactive Oxygen Species; Transglutaminases; Up-Regulation | 2013 |
Peroxiredoxin overexpression in MCF-7 breast cancer cells and regulation by cell proliferation and oxidative stress.
Topics: Acetylcysteine; Anthracenes; Antioxidants; Breast Neoplasms; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; RNA, Messenger; Up-Regulation | 2013 |
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hyperglycemia; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
The protective mechanism of QGC in feline esophageal epithelial cells by interleukin-1β treatment.
Topics: Acetylcysteine; Animals; Antioxidants; Cats; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Epithelial Cells; Esophageal Mucosa; Flavonoids; Fluoresceins; I-kappa B Kinase; Imidazoles; Interleukin-1beta; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Pyridines; Quercetin; Reactive Oxygen Species; Rumex; Signal Transduction | 2017 |
High glucose induced endothelial to mesenchymal transition in human umbilical vein endothelial cell.
Topics: Acetylcysteine; Actins; Antigens, CD; Cadherins; Cells, Cultured; Epithelial-Mesenchymal Transition; Flavonoids; Gene Expression Regulation; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Mitogen-Activated Protein Kinase 3; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1 | 2017 |
High Uric Acid Inhibits Cardiomyocyte Viability Through the ERK/P38 Pathway via Oxidative Stress.
Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hyperuricemia; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Uric Acid | 2018 |
Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Databases, Factual; Flavonoids; G2 Phase Cell Cycle Checkpoints; Humans; Isothiocyanates; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proportional Hazards Models; RNA Interference; RNA, Small Interfering; Sulfoxides; Tubulin | 2018 |
Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes.
Topics: Acetylcysteine; Antioxidants; Carcinogens, Environmental; Chromium; Dynamins; Flavonoids; Hepatocytes; Humans; Liver; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction | 2019 |
Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Movement; Chemokines; Chromones; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Male; Morpholines; Myocardium; Naphthalenes; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quaternary Ammonium Compounds; Rats, Wistar; Reactive Oxygen Species; Receptors, Chemokine | 2021 |