acetylcysteine and ondansetron

acetylcysteine has been researched along with ondansetron in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Deshpande, JK; Gregory, DF; Tobias, JD1
Scharman, EJ1
Bird, SB; Donovan, JL; Miller, MA; Navarro, M1
Amore, M; Ciccocioppo, R; Donnini, C; Gerra, G; Gerra, ML; Kalluppi, M; Malagoli, M; Raggi, MA; Saracino, MA; Somaini, L1
Bateman, DN; Coyle, J; Dear, JW; Eddleston, M; Gray, A; Lewis, S; Sandilands, EA; Thanacoody, HK; Thomas, SH; Webb, DJ1
Antoine, DJ; Park, K; Pirmohamed, M1
Bateman, DN; Butcher, I; Cooper, JG; Coyle, J; Dear, JW; Eddleston, M; Gray, A; Lewis, SC; Rodriguez, A; Sandilands, EA; Thanacoody, HK; Thomas, SH; Veiraiah, A; Vliegenthart, AD; Webb, DJ1
Hoffman, R; Kessler, B1
Bateman, DN; Dear, JW; Eddleston, M; Thanacoody, HK; Thomas, SH1
Bateman, DN1
Antoine, DJ; Bateman, DN; Clarke, JI; Cooper, JG; Dargan, PI; Dear, JW; Eddleston, M; Gray, A; Homer, NZ; Kimmitt, RA; Lewis, SC; Seymour, JH; Vliegenthart, A; Webb, DJ; Wood, DM1

Reviews

2 review(s) available for acetylcysteine and ondansetron

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Promising medications for cocaine dependence treatment.
    Recent patents on CNS drug discovery, 2011, May-01, Volume: 6, Issue:2

    Topics: Acetylcysteine; Atomoxetine Hydrochloride; Baclofen; Benzhydryl Compounds; Buprenorphine; Cocaine-Related Disorders; Fructose; Humans; Modafinil; Ondansetron; Patents as Topic; Propylamines; Topiramate

2011

Trials

2 trial(s) available for acetylcysteine and ondansetron

ArticleYear
Scottish and Newcastle antiemetic pre-treatment for paracetamol poisoning study (SNAP).
    BMC pharmacology & toxicology, 2013, Apr-04, Volume: 14

    Topics: Acetaminophen; Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Double-Blind Method; Humans; Ondansetron; Scotland; Vomiting

2013
Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.
    Lancet (London, England), 2014, Feb-22, Volume: 383, Issue:9918

    Topics: Acetaminophen; Acetylcysteine; Adult; Aged; Alanine Transaminase; Antiemetics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Liver Failure, Acute; Male; Middle Aged; Nausea; Ondansetron; Poisoning; Treatment Outcome; United Kingdom; Vomiting

2014

Other Studies

12 other study(ies) available for acetylcysteine and ondansetron

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Ondansetron to prevent emesis following N-acetylcysteine for acetaminophen intoxication.
    Pediatric emergency care, 1992, Volume: 8, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Female; Humans; Infusions, Intravenous; Ipecac; Ondansetron; Poisoning; Recurrence; Vomiting

1992
Use of ondansetron and other antiemetics in the management of toxic acetaminophen ingestions.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:1-2

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Analgesics, Non-Narcotic; Antidotes; Antiemetics; Female; Humans; Male; Ondansetron; Poison Control Centers; Retrospective Studies; Vomiting

1998
Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization?
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antidotes; Antiemetics; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Ondansetron; Poisoning; Retrospective Studies; Treatment Outcome

2007
Treatment of paracetamol overdose: room for improvement?
    Lancet (London, England), 2014, Feb-22, Volume: 383, Issue:9918

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antiemetics; Female; Humans; Male; Ondansetron; Vomiting

2014
Treatment of paracetamol overdose.
    Lancet (London, England), 2014, Apr-19, Volume: 383, Issue:9926

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antiemetics; Female; Humans; Male; Ondansetron; Vomiting

2014
Treatment of paracetamol overdose--authors' reply.
    Lancet (London, England), 2014, Apr-19, Volume: 383, Issue:9926

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antiemetics; Female; Humans; Male; Ondansetron; Vomiting

2014
Changing the Management of Paracetamol Poisoning.
    Clinical therapeutics, 2015, Volume: 37, Issue:9

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Anaphylaxis; Antidotes; Antiemetics; Biomarkers; Chemical and Drug Induced Liver Injury; Clinical Protocols; Free Radical Scavengers; HMGB1 Protein; Humans; MicroRNAs; Ondansetron; Vomiting

2015
Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury.
    Clinical pharmacology and therapeutics, 2017, Volume: 101, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Alanine Transaminase; Analgesics, Non-Narcotic; Antiemetics; Area Under Curve; Biomarkers; Chemical and Drug Induced Liver Injury; Cohort Studies; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Overdose; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Ondansetron; Reproducibility of Results; ROC Curve; Toxicokinetics; Young Adult

2017