acetylcysteine and omeprazole

acetylcysteine has been researched along with omeprazole in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's6 (35.29)29.6817
2010's8 (47.06)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Ammann, R; Flury, R; Meyenberger, C; Wirth, HP; Wüst, J; Zala, G1
Chen, X; Xie, Z; Zhong, D1
Krishna, M; Lalmuanpuii, J1
Demirturk, L; Gurbuz, AK; Ozel, AM; Ozturk, R; Yazgan, Y; Yildirim, S1
Chen, X; Hao, J; Hao, X; Lee, M; Liu, B; Reuhl, KR; Yang, CS; Zhang, B1
Bali, M; Gill, NS; Muthuraman, A; Sharma, PD; Sood, S1
Araújo, JH; Cardoso, MR; Dal-Pizzol, F; Daufenbach, JF; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Schwartsmann, G; Streck, EL1
Amali, A; Dabirmoghaddam, P; Hejazi, M; Motiee Langroudi, M; Samavati Fard, MR; Sharifian Razavi, M1
Hu, Z; Peng, Y; Shi, J; Su, M; Sun, C; Zhao, Y; Zheng, J1

Reviews

1 review(s) available for acetylcysteine and omeprazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for acetylcysteine and omeprazole

ArticleYear
[Omeprazole/amoxicillin: improved eradication of Helicobacter pylori in smokers because of N-acetylcysteine].
    Schweizerische medizinische Wochenschrift, 1994, Aug-09, Volume: 124, Issue:31-32

    Topics: Acetylcysteine; Adult; Aged; Amoxicillin; Drug Therapy, Combination; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Prospective Studies

1994
Effect of N-acetyl cysteine on Helicobacter pylori.
    Southern medical journal, 2005, Volume: 98, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcysteine; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Expectorants; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Stomach Diseases

2005
The effect of N-acetyl cysteine on laryngopharyngeal reflux.
    Acta medica Iranica, 2013, Volume: 51, Issue:11

    Topics: Acetylcysteine; Adult; Female; Humans; Laryngopharyngeal Reflux; Male; Middle Aged; Omeprazole; Placebos; Proton Pump Inhibitors

2013

Other Studies

13 other study(ies) available for acetylcysteine and omeprazole

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
    Journal of medicinal chemistry, 2018, 01-11, Volume: 61, Issue:1

    Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water

2018
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Metabolism of pantoprazole involving conjugation with glutathione in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcysteine; Administration, Oral; Animals; Anti-Ulcer Agents; Benzimidazoles; Chromatography, High Pressure Liquid; Glutathione; Magnetic Resonance Spectroscopy; Male; Omeprazole; Pantoprazole; Pyridines; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Sulfoxides

2005
Helicobacter pylori treatment.
    Southern medical journal, 2005, Volume: 98, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcysteine; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Expectorants; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole

2005
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
    International journal of cancer, 2009, Mar-15, Volume: 124, Issue:6

    Topics: Acetylcysteine; Adenocarcinoma; alpha-Tocopherol; Animals; Disease Models, Animal; Esophageal Neoplasms; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Vitamin A

2009
Role of 7,8-dimethoxycoumarin in anti-secretary and anti-inflammatory action on pyloric ligation-induced gastritis in rats.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:7

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Citrus; Coumarins; Gastritis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Omeprazole; Pylorus; Rats; Rats, Wistar

2010
Gastrin-releasing peptide receptor antagonist or N-acetylcysteine combined with omeprazol protect against mitochondrial complex II inhibition in a rat model of gastritis.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:3

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bombesin; Drug Therapy, Combination; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Gastric Mucosa; Gastritis; Indomethacin; Male; Mitochondria; Omeprazole; Peptide Fragments; Proton Pump Inhibitors; Rats; Rats, Wistar; Receptors, Bombesin; Severity of Illness Index; Stomach; Stomach Ulcer

2011
Evidence for Metabolic Activation of Omeprazole In Vitro and In Vivo.
    Chemical research in toxicology, 2022, 09-19, Volume: 35, Issue:9

    Topics: Acetylcysteine; Activation, Metabolic; Animals; Benzoquinones; Cytochrome P-450 CYP3A; Glutathione; Humans; Imines; Ketoconazole; Microsomes, Liver; Omeprazole; Proton Pump Inhibitors; Rats

2022