acetylcysteine and okadaic acid

acetylcysteine has been researched along with okadaic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's9 (50.00)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Los Ríos, C; Egea, J; Gálvez, E; García, AG; Iriepa, I; León, R; López, MG; Marco-Contelles, J; Moraleda, I; Romero, A; Samadi, A; Villarroya, M1
Arima, S; Inokoshi, J; Katagiri, M; Matsuzaki, K; Omura, S; Tanaka, H1
Fox, ES; Leingang, KA1
Callahan, KS; Clikeman, JA; Hoidal, JR; Terry, CM1
Chen, KD; Chen, LY; Cho, JH; Lai, MT; Lai, YK1
Antonicelli, F; Donaldson, K; Hirani, N; MacNee, W; Parmentier, M; Rahman, I1
Choi, I; Kang, HS1
Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T1
Griendling, KK; Rocic, P; Seshiah, P1
Chan, CB; De Leo, D; Der, S; Fantus, IG; Giacca, A; Guo, W; Koshkin, V; Li, H; Wang, X; Wheeler, MB1
Antonicelli, F; Brown, D; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I1
Martín, ME; O'Loghlen, A; Pérez-Morgado, MI; Salinas, M1
Chen, XQ; Liao, XM; Liu, GP; Ren, QG; Wang, JZ1
Arawaka, S; Fukushima, S; Hara, S; Kato, T; Koyama, S; Machiya, Y; Sakamoto, M; Sato, H1
Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J1
Anderson, D; Cemeli, E; Laffon, B; Méndez, J; Pásaro, E; Valdiglesias, V1
Bekier, ME; Borton, MT; Date, D; Dreier, MR; Taylor, WR1
Petrov, AM; Yakovleva, AA; Zefirov, AL1

Other Studies

18 other study(ies) available for acetylcysteine and okadaic acid

ArticleYear
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Calcium; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytotoxins; Electron Transport Chain Complex Proteins; Electrophorus; Glucose; Hippocampus; Humans; Isomerism; Models, Molecular; Naphthyridines; Neuroprotective Agents; Okadaic Acid; Oligomycins; Oxygen; Peptide Fragments; Protein Binding; Protein Phosphatase 2; Rats; Rotenone; Structure-Activity Relationship

2010
Neuronal differentiation of Neuro 2a cells by lactacystin and its partial inhibition by the protein phosphatase inhibitors calyculin A and okadaic acid.
    Biochemical and biophysical research communications, 1995, Nov-02, Volume: 216, Issue:1

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antifungal Agents; Biomarkers; Bucladesine; Cell Differentiation; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Ethers, Cyclic; Hydroquinones; Kinetics; Marine Toxins; Neurites; Neurons; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Pyrans; Spiro Compounds; Time Factors

1995
Inhibition of LPS-mediated activation in rat Kupffer cells by N-acetylcysteine occurs subsequent to NF-kappaB translocation and requires protein synthesis.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:4

    Topics: Acetylcysteine; Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kupffer Cells; Lipopolysaccharides; Macrophage Activation; Male; NF-kappa B; Okadaic Acid; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha

1998
TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Acetylcysteine; Blotting, Northern; Calcimycin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Interleukin-1; Ionophores; Marine Toxins; Membrane Proteins; Okadaic Acid; Oxazoles; Phospholipases A; Phospholipases A2; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins

1999
Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A.
    Journal of cellular biochemistry, 2000, Volume: 76, Issue:4

    Topics: Acetylcysteine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Imidazoles; Marine Toxins; Mitochondria; Mitogen-Activated Protein Kinases; Molecular Chaperones; Okadaic Acid; Oxazoles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Proline; Promoter Regions, Genetic; Pyridines; Rats; RNA, Messenger; Ruthenium Red; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured

2000
Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells.
    The European respiratory journal, 2000, Volume: 16, Issue:5

    Topics: Acetylcysteine; Cell Line; Cycloheximide; Enzyme Inhibitors; Glutathione; Humans; Interleukin-1; Lipopolysaccharides; Macrophages; NF-kappa B; Okadaic Acid; Protein Isoforms; Protein Synthesis Inhibitors; RNA, Messenger

2000
Protein phosphatase 2A modulates the proliferation of human multiple myeloma cells via regulation of the production of reactive oxygen intermediates and anti-apoptotic factors.
    Cellular immunology, 2001, Oct-10, Volume: 213, Issue:1

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Division; Enzyme Inhibitors; Gene Expression; Glutathione; Humans; Interleukin-6; Intracellular Fluid; Mice; Multiple Myeloma; NF-kappa B; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Transfection; Tumor Cells, Cultured

2001
Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35.
    Brain research. Molecular brain research, 2002, Oct-15, Volume: 106, Issue:1-2

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Animals, Newborn; Brain Chemistry; Calpain; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Embryo, Mammalian; Enzyme Inhibitors; Hippocampus; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Okadaic Acid; Phosphorylation; Proteasome Endopeptidase Complex; Purines; Rats; Rats, Wistar; Roscovitine

2002
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors

2003
Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.
    Diabetes, 2004, Volume: 53, Issue:1

    Topics: Acetylcysteine; Animals; Cell Line; Enzymes; Gene Expression Profiling; Islets of Langerhans; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Protein Kinases; Reactive Oxygen Species; RNA Processing, Post-Transcriptional

2004
Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Chemotaxis; Cycloheximide; Enzyme Inhibitors; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Lipopolysaccharides; Lysine; Male; Monocytes; Neutrophils; Okadaic Acid; Pneumonia; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors

2004
N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways.
    Cellular signalling, 2006, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Carrier Proteins; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factor-4G; Hydrogen Peroxide; Imidazoles; Intracellular Signaling Peptides and Proteins; Okadaic Acid; PC12 Cells; Phosphoproteins; Pyridines; Rats; Signal Transduction; Sirolimus

2006
Effects of tau phosphorylation on proteasome activity.
    FEBS letters, 2007, Apr-03, Volume: 581, Issue:7

    Topics: Acetylcysteine; Cells, Cultured; Colforsin; Cysteine Proteinase Inhibitors; Humans; Okadaic Acid; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; tau Proteins

2007
Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
    The Journal of biological chemistry, 2010, Dec-24, Volume: 285, Issue:52

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Cell Line, Tumor; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Lewy Bodies; Neurons; Okadaic Acid; Parkinson Disease; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Phosphatase 1; Protein Phosphatase 2; Protein Synthesis Inhibitors; Rabbits; Ubiquitin

2010
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:2

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells

2011
Induction of oxidative DNA damage by the marine toxin okadaic acid depends on human cell type.
    Toxicon : official journal of the International Society on Toxinology, 2011, Volume: 57, Issue:6

    Topics: Acetylcysteine; Catalase; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Glycosylases; Humans; Leukocytes; Marine Toxins; Okadaic Acid; Oxidative Stress; Statistics, Nonparametric

2011
Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation.
    Journal of biochemistry, 2012, Volume: 151, Issue:4

    Topics: Acetylcysteine; Amino Acid Substitution; CDC2 Protein Kinase; Cell Cycle Proteins; Dual-Specificity Phosphatases; Gene Expression; HeLa Cells; Humans; Leupeptins; Okadaic Acid; Peptide Fragments; Phosphoric Monoester Hydrolases; Phosphorylation; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Ubiquitin

2012
Role of membrane cholesterol in spontaneous exocytosis at frog neuromuscular synapses: reactive oxygen species-calcium interplay.
    The Journal of physiology, 2014, Nov-15, Volume: 592, Issue:22

    Topics: Acetophenones; Acetylcysteine; Animals; beta-Cyclodextrins; Calcium; Calcium Signaling; Capsaicin; Cholesterol; Cyclosporine; Exocytosis; Neuromuscular Junction; Okadaic Acid; Ranidae; Reactive Oxygen Species; Ruthenium Red; Synaptic Membranes; TRPV Cation Channels

2014