acetylcysteine has been researched along with naphthoquinones in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.88) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 12 (29.27) | 29.6817 |
| 2010's | 22 (53.66) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Highet, RJ; Hill, BA; Jones, TW; Lau, SS; Monks, TJ | 1 |
| Lewis, DC; Shibamoto, T | 1 |
| Iwata, S; Maesato, T | 1 |
| Chau, YP; Don, MJ; Kuo, ML; Shiah, SG | 1 |
| Hooper, AM; Rickards, RW | 1 |
| Aggarwal, BB; Gad, YP; Manna, SK; Mukhopadhyay, A | 1 |
| Böddinghaus, B; Brade, V; Briner, VA; Dorsch, S; Franzen, R; Huwiler, A; Pautz, A; Pfeilschifter, J | 1 |
| Gao, D; Hiromura, M; Sakurai, H; Yasui, H | 1 |
| Lindstrom, AB; Rappaport, SM; Troester, MA; Waidyanatha, S | 1 |
| Gao, F; Shi, GY; Tang, XM; Yi, J; Yuan, JQ | 1 |
| Aiuchi, T; Hori, K; Horie, M; Kajimoto, S; Masuda, Y; Nakajo, S; Nakaya, K; Shibayama-Imazu, T; Shima, G | 1 |
| Cai, YJ; Chen, Y; Ding, J; Huang, M; Lu, HR; Miao, ZH; Zhang, JS; Zhu, H | 1 |
| Brüne, B; Callapina, M; Köhl, R; Schmid, T; Zhou, J | 1 |
| Brüne, B; Köhl, R; Zhou, J | 1 |
| Goto, R; Ibuki, Y; Toyooka, T | 1 |
| Cai, Y; Ding, J; Lin, L; Lu, J; Miao, Z | 1 |
| Powolny, AA; Singh, SV | 1 |
| Hazra, B; Kumar, A; Kumar, B; Mishra, KP; Pandey, BN | 1 |
| Gammon, DW; Hunter, R; Marakalala, MJ; Mavumengwana, V; Mudzunga, TT; Munyololo, M; Steenkamp, DJ | 1 |
| Chang, IC; Chiang, TI; Hsu, LS; Huang, YJ; Yeh, CW | 1 |
| Lombard, C; McKallip, RJ; Ramakrishnan, R; Sun, J | 1 |
| McKallip, RJ; Sun, J | 1 |
| Ghosh, S; Hazra, B; Kumar, A; Kumar, B; Mishra, KP; Pandey, BN | 1 |
| Bigda, J; Kawiak, A; Lojkowska, E; Stasilojc, G; Wasilewska, A; Zawacka-Pankau, J | 1 |
| Jiang, YF; Qu, SC; Qu, XR; Sui, da Y; Xu, HL; Yu, XF | 1 |
| Chen, CH; Lin, ML; Ong, PL; Yang, JT | 1 |
| Andreatta, P; Boschetti, S; Gatti, R | 1 |
| Cao, Y; Fu, Z; Jiang, Y; Li, C; Lu, H; Miao, H; Shang, Q; Wang, L; Zhao, L | 1 |
| Cho, Y; Park, S; Shin, H | 1 |
| Baptista Ferreira, S; Barreiro Arcos, ML; Cremaschi, G; Di Rosso, ME; Dubin, M; Elingold, I; Ferreira, VF; Galleano, M; Sterle, H | 1 |
| Chao, JI; Chen, C; Liao, WS; Murugan, K; Wu, YH; Yang, CR | 1 |
| Hseu, YC; Hsu, LS; Hunag, JE; Kao, SH; Lee, MJ; Sheu, GT; Wang, CJ; Yeh, CW | 1 |
| Choi, EJ; Hong, MP; Kie, JH; Kim, HR; Lee, A; Lee, HK; Lim, W; Moon, BI; Seoh, JY | 1 |
| Duan, MH; Fu, YJ; Ma, WD; Sun, Y; Wang, P; Yao, XH; Yu, B; Zou, YP | 1 |
| Agostinelli, S; Arcuri, G; Bielli, A; Costanza, G; Doldo, E; Ferlosio, A; Orlandi, A; Scioli, MG; Tarquini, C | 1 |
| Deng, YT; Hsieh, YP; Kuo, MY; Wu, KJ; Yang, WH | 1 |
| Angerer, J; Klotz, K | 1 |
| Chen, W; Huang, H; Pan, Y; Xia, Y; Xie, H; Zheng, K | 1 |
| Fang, SH; Fu, YJ; Gao, C; Li, J; Wang, P; Wang, W; Yao, LP; Zhang, J; Zhang, SD | 1 |
| Feng, YC; Jin, CH; Li, JQ; Luo, YH; Piao, XJ; Shen, GN; Wang, CY; Wang, JR; Xu, WT; Zhang, T; Zhang, Y | 1 |
| Boga, C; Calonghi, N; Di Foggia, M; Esposito, E; Farruggia, G; Fiori, J; Micheletti, G; Rizzardi, N; Taddei, P; Zalambani, C | 1 |
41 other study(ies) available for acetylcysteine and naphthoquinones
| Article | Year |
|---|---|
Differences in the localization and extent of the renal proximal tubular necrosis caused by mercapturic acid and glutathione conjugates of 1,4-naphthoquinone and menadione.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Glutathione; Kidney Cortex; Kidney Medulla; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Magnetic Resonance Spectroscopy; Male; Naphthoquinones; Rats; Rats, Inbred Strains; Vitamin K | 1990 |
Relative metabolism of quinones to semiquinone radicals in xanthine oxidase system.
Topics: 1-Propanol; Acetylcysteine; Anthraquinones; Benzoquinones; Cytochrome c Group; Ethanol; Naphthoquinones; Oxidation-Reduction; Quinones; Xanthine Oxidase | 1989 |
Studies on the mercapturic acid pathway in the rabbit lens.
Topics: Acetylcysteine; Animals; Aqueous Humor; Cataract; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Glutathione Transferase; Lens, Crystalline; Naphthalenes; Naphthoquinones; Rabbits | 1988 |
Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Differentiation; DNA Fragmentation; Drug Resistance; Enzyme Inhibitors; Glutathione; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Monocytes; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vitamin E | 1998 |
3-amino-5-hydroxybenzoic acid in antibiotic biosynthesis. XI. Biological origins and semisynthesis of thionaphthomycins, and the structures of naphthomycins I and J.
Topics: Acetylcysteine; Aminobenzoates; Anthraquinones; Anti-Bacterial Agents; Fermentation; Hydroxybenzoates; Lactams, Macrocyclic; Magnetic Resonance Spectroscopy; Molecular Structure; Naphthoquinones; Streptomyces | 1998 |
Suppression of tumor necrosis factor-activated nuclear transcription factor-kappaB, activator protein-1, c-Jun N-terminal kinase, and apoptosis by beta-lapachone.
Topics: Acetylcysteine; Apoptosis; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Cell Line; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Gene Expression; Genes, Reporter; HeLa Cells; Humans; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Naphthoquinones; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Superoxide potently induces ceramide formation in glomerular endothelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cattle; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Hypoxanthine; Kidney Glomerulus; Naphthoquinones; Superoxides; Vitamin K; Xanthine Oxidase | 2001 |
Direct reaction between shikonin and thiols induces apoptosis in HL60 cells.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; DNA Fragmentation; Enzyme Activation; HL-60 Cells; Humans; Lipid Peroxides; Naphthoquinones; Sulfhydryl Compounds | 2002 |
Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats.
Topics: Acetylcysteine; Animals; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Mesylates; Molecular Structure; Naphthalenes; Naphthoquinones; Protein Binding; Rats; Rats, Inbred F344; Sensitivity and Specificity; Serum Albumin | 2002 |
The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of reactive oxygen species.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Catalase; Cell Cycle; Cell Division; Cell Line, Tumor; Dactinomycin; Flow Cytometry; Fluoresceins; Humans; In Situ Nick-End Labeling; Interphase; Naphthoquinones; Oxides; Propidium; Reactive Oxygen Species | 2004 |
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Coloring Agents; Cytochromes c; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Genetic Vectors; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Mitochondria; Naphthoquinones; Oligonucleotide Array Sequence Analysis; Plasmids; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection | 2004 |
Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; DNA; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Naphthoquinones; Nuclear Proteins; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Topoisomerase II Inhibitors | 2005 |
NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Carcinoma, Hepatocellular; Cell Line; Humans; Hydroxylation; Hypoxia; Naphthoquinones; Nitric Oxide; Nitric Oxide Donors; Procollagen-Proline Dioxygenase; Reactive Oxygen Species; Triazenes; Tumor Cells, Cultured; Von Hippel-Lindau Tumor Suppressor Protein | 2005 |
Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Apoptosis; Catalase; Cell Extracts; Cell Line; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Naphthoquinones; Nitric Oxide; Peroxynitrous Acid; Protein Biosynthesis; Reactive Oxygen Species; Time Factors; Transcriptional Activation | 2006 |
Inhibition of apoptosis by menadione on exposure to UVA.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; DNA Fragmentation; Mice; Naphthoquinones; NIH 3T3 Cells; Peroxides; Ultraviolet Rays; Vitamin K 3 | 2006 |
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Hydrogen Peroxide; K562 Cells; Naphthoquinones; Reactive Oxygen Species | 2007 |
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Male; Naphthoquinones; Oxidation-Reduction; Peroxidases; Prostatic Neoplasms; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells.
Topics: Acetylcysteine; Allopurinol; Animals; Antimycin A; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cardiolipins; Cell Line, Tumor; Cyclosporine; Cytochromes c; Female; Free Radical Scavengers; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rotenone; Uncoupling Agents; Vitamin K 3 | 2009 |
Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol.
Topics: Acetylcysteine; Amidohydrolases; Bacterial Proteins; Cell Survival; Cysteine; Enzyme Inhibitors; Glycopeptides; Indicators and Reagents; Inositol; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Naphthoquinones; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Thioglucosides | 2010 |
Shikonin induces apoptosis through reactive oxygen species/extracellular signal-regulated kinase pathway in osteosarcoma cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Humans; Inhibitory Concentration 50; Naphthoquinones; Osteosarcoma; Phosphorylation; Phytotherapy; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2010 |
Plumbagin-induced apoptosis in lymphocytes is mediated through increased reactive oxygen species production, upregulation of Fas, and activation of the caspase cascade.
Topics: Acetylcysteine; Animals; Apoptosis; Atrophy; Caspases; Dinitrofluorobenzene; Enterotoxins; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; fas Receptor; Female; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Lymphocytes; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Spleen; Thymus Gland; Up-Regulation | 2010 |
Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Catalase; Cell Survival; Flow Cytometry; Gene Expression; Humans; In Situ Nick-End Labeling; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Polyethylene Glycols; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction | 2011 |
Diospyrin derivative, an anticancer quinonoid, regulates apoptosis at endoplasmic reticulum as well as mitochondria by modulating cytosolic calcium in human breast carcinoma cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Calcium; Calcium Channels; Carcinoma; Cell Line, Tumor; Chelating Agents; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Estrenes; Female; Humans; Mitochondria; Naphthoquinones; Oxidation-Reduction; Phosphodiesterase Inhibitors; Pyrrolidinones; Ruthenium Red; Type C Phospholipases | 2012 |
Induction of apoptosis in HL-60 cells through the ROS-mediated mitochondrial pathway by ramentaceone from Drosera aliciae.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Drosera; Drug Screening Assays, Antitumor; Free Radical Scavengers; HL-60 Cells; Humans; Mitochondria; Molecular Structure; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2012 |
Juglone, from Juglans mandshruica Maxim, inhibits growth and induces apoptosis in human leukemia cell HL-60 through a reactive oxygen species-dependent mechanism.
Topics: Acetylcysteine; Annexin A5; Antioxidants; Apoptosis; Caspases; Cell Division; Cytochromes c; Enzyme Activation; Glutathione; HL-60 Cells; Humans; Juglans; Leukemia; Membrane Potentials; Naphthoquinones; Reactive Oxygen Species | 2012 |
Novel multiple apoptotic mechanism of shikonin in human glioma cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Catalase; Cell Line, Tumor; Cyclosporine; G1 Phase Cell Cycle Checkpoints; Glioma; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidative Stress; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Toluene; Tumor Suppressor Protein p53 | 2012 |
Study of 1,4-naphthoquinone as a new useful derivatization reagent for LC analysis of aliphatic thiols in dietary supplements and pharmaceuticals.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Dietary Supplements; Naphthoquinones; Pharmaceutical Preparations; Sulfhydryl Compounds | 2013 |
Inhibitory effect of Shikonin on Candida albicans growth.
Topics: Acetylcysteine; Antifungal Agents; Candida albicans; Gene Expression Regulation, Fungal; Genes, Fungal; Glutathione; Membrane Potential, Mitochondrial; Microbial Sensitivity Tests; Naphthoquinones; Reactive Oxygen Species | 2012 |
Shikonin induces programmed necrosis-like cell death through the formation of receptor interacting protein 1 and 3 complex.
Topics: Acetylcysteine; Animals; Apoptosis; Mice; Naphthoquinones; NIH 3T3 Cells; Protein Binding; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases | 2013 |
Novel o-naphthoquinones induce apoptosis of EL-4 T lymphoma cells through the increase of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Benzopyrans; Benzoquinones; Cell Line, Tumor; Cell Nucleus Shape; Cell Proliferation; Cell Survival; Chromatin Assembly and Disassembly; Free Radical Scavengers; Glutathione; Kinetics; Lymphoma, T-Cell; Membrane Potential, Mitochondrial; Mice; Naphthoquinones; Reactive Oxygen Species; Trypanocidal Agents; Up-Regulation | 2013 |
CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.
Topics: Acetylcysteine; Aged; Animals; Apoptosis; Cell Survival; Cytochromes c; Female; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species; Survivin; Vitamin K 3 | 2013 |
Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Flow Cytometry; Free Radical Scavengers; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Necrosis; Phosphorylation; Reactive Oxygen Species; Stomach Neoplasms; Time Factors | 2014 |
Reactive oxygen species prevent imiquimod-induced psoriatic dermatitis through enhancing regulatory T cell function.
Topics: Acetylcysteine; Aminoquinolines; Animals; Dermatitis; Disease Progression; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hyperbaric Oxygenation; Imiquimod; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice, Inbred C57BL; NADPH Oxidases; Naphthoquinones; Psoriasis; Reactive Oxygen Species; T-Lymphocytes, Regulatory | 2014 |
Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway.
Topics: Acetylcysteine; Annexin A5; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caspase 3; Caspase 9; Cell Proliferation; DNA Fragmentation; Fluorescein-5-isothiocyanate; Humans; Inhibitory Concentration 50; MCF-7 Cells; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Passiflora; Propidium; Reactive Oxygen Species | 2014 |
Antioxidant treatment prevents serum deprivation- and TNF-α-induced endothelial dysfunction through the inhibition of NADPH oxidase 4 and the restoration of β-oxidation.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Carnitine; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Cytokines; Cytoprotection; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Mitochondria; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; RNA Interference; Serum; Transfection; Tumor Necrosis Factor-alpha | 2014 |
NADPH Oxidase 4 Mediates TGFβ1-induced CCN2 in Gingival Fibroblasts.
Topics: Acetylcysteine; Cell Culture Techniques; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Free Radical Scavengers; Gene Silencing; Gingiva; Gingival Overgrowth; Humans; MAP Kinase Signaling System; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Smad3 Protein; src-Family Kinases; Superoxides; Transforming Growth Factor beta1 | 2015 |
Quantification of naphthoquinone mercapturic acids in urine as biomarkers of naphthalene exposure.
Topics: Acetylcysteine; Biomarkers; Chromatography, Liquid; Environmental Exposure; Humans; Limit of Detection; Linear Models; Naphthoquinones; Reproducibility of Results; Tandem Mass Spectrometry | 2016 |
Plumbagin Triggers ER Stress-Mediated Apoptosis in Prostate Cancer Cells via Induction of ROS.
Topics: Acetylcysteine; Activating Transcription Factor 4; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; eIF-2 Kinase; Endoplasmic Reticulum Stress; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; Transcription Factor CHOP; Transplantation, Heterologous | 2018 |
Juglone induces apoptosis and autophagy via modulation of mitogen-activated protein kinase pathways in human hepatocellular carcinoma cells.
Topics: Acetylcysteine; Adenine; Amino Acid Chloromethyl Ketones; Androstadienes; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Enzyme Activation; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Wortmannin | 2018 |
The design of 1,4-naphthoquinone derivatives and mechanisms underlying apoptosis induction through ROS-dependent MAPK/Akt/STAT3 pathways in human lung cancer cells.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Drug Design; G1 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinases; Naphthoquinones; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor | 2019 |
Synthesis of thia-Michael-Type Adducts between Naphthoquinones and
Topics: Acetylcysteine; Cell Line, Tumor; HeLa Cells; Humans; Naphthoquinones; Neuroblastoma; Reactive Oxygen Species | 2022 |