acetylcysteine and naloxone

acetylcysteine has been researched along with naloxone in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's3 (13.04)18.2507
2000's6 (26.09)29.6817
2010's7 (30.43)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Heller, MB1
Tenenbein, M1
Lange, PG; Moores, K1
Prescott, LF1
Litovitz, TL1
Proudfoot, AT2
Bernard, GR; Weikert, LF1
Bowden, CA; Krenzelok, EP1
Cadet, P; Goumon, Y; Hempelmann, G; Hughes, TK; Menges, T; Menzebach, A; Stefano, GB; Welters, ID1
Bailey, B; Bussières, JF1
Dines, A1
Choi, DH; Jung, EB; Kim, MS; Kim, TY; Lee, J; Moon, SK; Park, C; Park, R1
Cechinel-Filho, V; Gurgel, LA; Lima-Júnior, RC; Martins, DT; Rao, VS; Santos, FA1
Hoffman, RS1
Traynor, JR; Wang, Q1
Cooper, JG; Teo, AI1
Heppell, SPE; Isbister, GK1
Goldberger, D; Vearrier, D1
Brown, TR; Jenkins, DD; Kalivas, P; Moss, HG; Ward, P1

Reviews

6 review(s) available for acetylcysteine and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pediatric toxicology: current controversies and recent advances.
    Current problems in pediatrics, 1986, Volume: 16, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Child Abuse; Child, Preschool; Digitoxin; Digoxin; Emetics; Female; Gastric Lavage; Humans; Hydrocarbons; Immunoglobulin Fab Fragments; Infant; Male; Naloxone; Narcotics; Poisoning

1986
The anecdotal antidotes.
    Emergency medicine clinics of North America, 1984, Volume: 2, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Antidotes; Child; Cimetidine; Female; Ferrocyanides; Folic Acid; Heart Diseases; Humans; Magnesium; Male; Middle Aged; Naloxone; Niacinamide; Physostigmine; Poisoning; Pyridoxine; Thioctic Acid

1984
Antidotes: benefits and risks.
    Toxicology letters, 1995, Volume: 82-83

    Topics: Acetylcysteine; Animals; Antidotes; Deferoxamine; Flumazenil; Humans; Naloxone

1995
Pharmacotherapy of sepsis.
    Clinics in chest medicine, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bradykinin; Cyclooxygenase Inhibitors; Humans; Naloxone; Pentoxifylline; Platelet Activating Factor; Sepsis

1996
Clinical applications of commonly used contemporary antidotes. A US perspective.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer

1997

Other Studies

17 other study(ies) available for acetylcysteine and naloxone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Overdoses.
    American family physician, 1985, Volume: 31, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cathartics; Charcoal; Humans; Hypnotics and Sedatives; Ipecac; Naloxone; Narcotics; Parasympatholytics; Poisoning; Salicylates

1985
Antidotes in the treatment of acute poisoning.
    Iowa medicine : journal of the Iowa Medical Society, 1987, Volume: 77, Issue:8

    Topics: Acetylcysteine; Antidotes; Digoxin; Ethanol; Glucagon; Humans; Immunoglobulin Fab Fragments; Methylene Blue; Naloxone; Poisoning; Pyridoxine

1987
New approaches in managing drug overdosage and poisoning.
    British medical journal (Clinical research ed.), 1983, Jul-23, Volume: 287, Issue:6387

    Topics: Acetaminophen; Acetylcysteine; Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Child; Cholinesterase Inhibitors; Glucagon; Humans; Immunotherapy; Intestinal Absorption; Methionine; Naloxone; Physostigmine; Poisoning; Poisons; Self Administration

1983
Clinical features and management of Distalgesic overdose.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Acetaminophen; Acetylcysteine; Dextropropoxyphene; Drug Combinations; Drug Interactions; Humans; Naloxone

1984
Morphine inhibits NF-kappaB nuclear binding in human neutrophils and monocytes by a nitric oxide-dependent mechanism.
    Anesthesiology, 2000, Volume: 92, Issue:6

    Topics: Acetylcysteine; Analgesics, Opioid; Cell Nucleus; Enzyme Inhibitors; Flow Cytometry; Humans; In Vitro Techniques; Lipopolysaccharides; Male; Monocytes; Morphine; Naloxone; Narcotic Antagonists; Neutrophils; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Binding; Receptors, Opioid, mu

2000
Antidote availability in Quebec hospital pharmacies: impact of N-acetylcysteine and naloxone consumption.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2000,Winter, Volume: 7, Issue:4

    Topics: Acetylcysteine; Antidotes; Drug Utilization Review; Humans; Naloxone; Pharmacy Service, Hospital; Quebec; Surveys and Questionnaires

2000
Antidotes.
    Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2001, Volume: 9, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Free Radical Scavengers; Humans; Naloxone; Narcotic Antagonists; Narcotics

2001
Morphine prevents glutamate-induced death of primary rat neonatal astrocytes through modulation of intracellular redox.
    Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:1

    Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Astrocytes; Benzeneacetamides; Benzimidazoles; Bisbenzimidazole; Carbocyanines; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Glutamic Acid; Glutathione; Hydrogen Peroxide; Ion Channels; Microscopy, Fluorescence; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Morphine; Naloxone; Narcotic Antagonists; Neuroglia; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123

2004
Dragon's blood from Croton urucurana (Baill.) attenuates visceral nociception in mice.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Abdominal Pain; Acetylcysteine; Administration, Oral; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Capsaicin; Clonidine; Croton; Cyclophosphamide; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Pentobarbital; Plant Extracts; Sleep; Time Factors

2007
Toxicology from across the pond.
    The journal of the Royal College of Physicians of Edinburgh, 2010, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Antidotes; Child; Fat Emulsions, Intravenous; Humans; Naloxone; Poisoning; Risk Factors; Substance-Related Disorders; Suicide

2010
Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.
    The Journal of biological chemistry, 2011, Mar-11, Volume: 286, Issue:10

    Topics: Acetylcysteine; Analgesics, Opioid; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; HEK293 Cells; Humans; Leupeptins; Naloxone; Narcotic Antagonists; Pertussis Toxin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha-2; Receptors, Bradykinin; Receptors, Opioid, delta; Receptors, Opioid, mu; RGS Proteins; Signal Transduction; Time Factors; Ubiquitination

2011
The epidemiology and management of adult poisonings admitted to the short-stay ward of a large Scottish emergency department.
    Scottish medical journal, 2013, Volume: 58, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Antidotes; Central Nervous System Depressants; Charcoal; Drug Overdose; Emergency Service, Hospital; Ethanol; Female; Follow-Up Studies; Free Radical Scavengers; Hospitalization; Humans; Length of Stay; Male; Mental Disorders; Middle Aged; Naloxone; Narcotic Antagonists; Patient Admission; Patient Discharge; Public Health; Retrospective Studies; Scotland; Self-Injurious Behavior

2013
Lack of respiratory depression in paracetamol-codeine combination overdoses.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Child; Codeine; Critical Care; Drug Combinations; Drug Overdose; Female; Glasgow Coma Scale; Humans; Length of Stay; Male; Middle Aged; Naloxone; Narcotic Antagonists; Respiration, Artificial; Respiratory Insufficiency; Retrospective Studies; Suicide, Attempted; Treatment Outcome; Young Adult

2017
Evaluation of a Food and Drug Administration Mandate to Limit Acetaminophen in Prescription Combination Products.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2017, Volume: 13, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug and Narcotic Control; Drug Approval; Drug Combinations; Drug Compounding; Drug Overdose; Female; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Poison Control Centers; Policy Making; Pregnancy; Prescription Drugs; Program Evaluation; Protective Factors; Risk Factors; Time Factors; United States; United States Food and Drug Administration; Young Adult

2017
N-acetylcysteine mitigates acute opioid withdrawal behaviors and CNS oxidative stress in neonatal rats.
    Pediatric research, 2020, Volume: 88, Issue:1

    Topics: Acetylcysteine; Analgesics, Opioid; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System; Female; Glutamic Acid; Glutathione; Magnetic Resonance Spectroscopy; Maternal Exposure; Naloxone; Neonatal Abstinence Syndrome; Osmosis; Oxidative Stress; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley

2020