acetylcysteine has been researched along with nadp in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (21.62) | 18.7374 |
| 1990's | 4 (10.81) | 18.2507 |
| 2000's | 13 (35.14) | 29.6817 |
| 2010's | 9 (24.32) | 24.3611 |
| 2020's | 3 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kramer, RA | 1 |
| Fischer, V; Mason, RP; Schreiber, J; Takahashi, N | 1 |
| Kammerer, RC; Lampe, MA | 1 |
| McCay, PB; Powell, SR | 1 |
| Araya, H; Awazu, S; Hayashi, M; Horie, T | 1 |
| Smith, AG; Stewart, FP | 1 |
| Repine, JE; White, CW | 1 |
| Farber, JL; Hoek, JB; Starke, PE | 1 |
| Cadenas, E; Forman, HJ; Qiu, X; Schönthal, AH | 1 |
| Numazawa, M; Tachibana, M | 1 |
| Castranova, V; Colburn, NH; Ding, M; Leonard, SS; Li, JJ; Shi, X; Vallyathan, V; Ye, JP | 1 |
| Cederbaum, AI; Goasduff, T | 1 |
| Rozanski, GJ; Xu, Z | 1 |
| Aw, TY; Pias, EK | 1 |
| Suntres, ZE | 1 |
| Lee, JH; Park, JE; Park, JW; Yang, ES; Yang, JH; Yoon, SJ | 1 |
| Descamps-Latscha, B; Drüeke, T; Gausson, V; Nguyen, AT; Santangelo, F; Touam, M; Witko-Sarsat, V | 1 |
| Cui, X; Hayakawa, T; Hirano, S; Kanno, S; Kobayashi, Y; Li, S; Shraim, A | 1 |
| Johnson, BM; van Breemen, RB | 1 |
| Baer, BR; Henne, KR; Rettie, AE | 1 |
| Im, MJ; Kim, BJ; Kim, UH; Okamoto, H; Park, KH; Takasawa, S; Yim, CY | 1 |
| Asbury, CR; Aykin-Burns, N; Coleman, MC; Cullen, JJ; Daniels, D; Du, J; Li, L; Smith, BJ; Spitz, DR | 1 |
| Chang, ZJ; Wang, NL; Zhang, L; Zhang, W | 1 |
| Carlson, L; Chen, W; Foll, R; Guan, X; Hanson, S; Herman, J; Raza, AS; Seefeldt, T; Stoebner, A; Zhao, Y | 1 |
| Chen, W; Guan, X; Hu, Y; Matthees, D; Seefeldt, T; Wang, X; Zhao, Y | 1 |
| Chen, N; Ko, M | 1 |
| Choudhury, M; Jackson, D; Park, PH; Shukla, SD | 1 |
| Daniels, JS; Gan, LS; LeDuc, BW; Mahajan, MK; Uttamsingh, V; Williams, DA | 1 |
| Muller, M | 1 |
| Du, J; King, I; Nassar, AE | 1 |
| Cho, EW; Kim, IG; Kim, JS; Lee, JH | 1 |
| Burant, CF; Davis, M; Dresser, J; Feng, FY; Kachman, M; Lawrence, TS; Lyssiotis, CA; Morgan, MA; Parsels, JD; Speers, C; Wahl, DR; Wernisch, S; Wilder-Romans, K; Zhao, L; Zhao, SG | 1 |
| Ku, HJ; Lee, JH; Park, JH; Park, JW | 1 |
| Bandyopadhaya, A; Rahme, LG; Tzika, AA | 1 |
| Cao, MM; Li, YM; Sun, B; Xu, C; Yang, LY; Yu, L; Zhao, YR | 1 |
| Dong, Y; Du, GF; Fan, X; Le, YJ; Yang, XY; Yin, A | 1 |
| Kang, J; Liu, S; Shen, Q; Wu, H; Yao, Q; Zou, X | 1 |
2 review(s) available for acetylcysteine and nadp
| Article | Year |
|---|---|
Pulmonary antioxidant defense mechanisms.
Topics: Acetylcysteine; Animals; Antioxidants; Diet; Dietary Fats; Dietary Proteins; Dimethyl Sulfoxide; Glutathione Peroxidase; Lipid Peroxides; Lung; Mammals; Models, Biological; NADP; Polyethylene Glycols; Superoxide Dismutase; Thiourea; Vitamin E | 1985 |
Role of antioxidants in paraquat toxicity.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E | 2002 |
1 trial(s) available for acetylcysteine and nadp
| Article | Year |
|---|---|
In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh).
Topics: Acetaminophen; Acetylcysteine; Adult; Biotransformation; Catechols; Cimicifuga; Dietary Supplements; Dose-Response Relationship, Drug; Female; Glutathione; Humans; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; NADP; Plant Extracts; Quinones | 2003 |
34 other study(ies) available for acetylcysteine and nadp
| Article | Year |
|---|---|
Cytochrome P-450-dependent formation of alkylating metabolites of the 2-chloroethylnitrosoureas MeCCNU and CCNU.
Topics: Acetylcysteine; Alkylating Agents; Alkylation; Animals; Biotransformation; Cytochrome P-450 Enzyme System; DNA; Glutathione; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred F344; Semustine | 1989 |
An ESR study of nonenzymatic reactions of nitroso compounds with biological reducing agents.
Topics: Acetylcysteine; Chemical Phenomena; Chemistry; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; NADP; Naphthalenesulfonates; Nitroso Compounds; Oxidation-Reduction | 1988 |
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
Inhibition of doxorubicin-initiated membrane damage by N-acetylcysteine: possible mediation by a thiol-dependent, cytosolic inhibitor of lipid peroxidation.
Topics: Acetylcysteine; Animals; Cytosol; Doxorubicin; Heart; Iodoacetates; Iodoacetic Acid; Lipid Peroxides; Male; Membranes; NADP; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1988 |
Alteration in rat liver microsomal membranes induced by acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Animals; Cytochrome P-450 Enzyme System; Fluorescence Polarization; Male; Membranes; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains | 1987 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes.
Topics: Acetylcysteine; Animals; Calcium; Cell Survival; Cells, Cultured; Deferoxamine; Dithiothreitol; Glucose Oxidase; Glutathione; Homeostasis; Hydrogen Peroxide; Iron; Liver; Male; NADP; Onium Compounds; Phosphorylase a; Rats; Rats, Inbred Strains; Trityl Compounds; Vitamin K | 1986 |
Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.
Topics: Acetylcysteine; Alanine; Antineoplastic Agents; Aziridines; Benzoquinones; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dicumarol; Enzyme Inhibitors; Free Radicals; Humans; Hydrogen Peroxide; NADP; Oxidation-Reduction; Oxygen; Tumor Cells, Cultured | 1996 |
Aromatase inactivation by a suicide substrate, androst-5-ene-4,7,17-trione: the 5beta,6beta-epoxy-19-oxo derivative, as a possible reactive electrophile irreversibly binding to the active site.
Topics: Acetylcysteine; Androstanes; Androstenedione; Androstenes; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Cysteine; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta; Pregnancy | 1997 |
Vanadate-induced activation of activator protein-1: role of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Epidermal Cells; Formates; Free Radical Scavengers; Gene Expression Regulation; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Mice; NADP; Naphthalenes; Oxidation-Reduction; Oxygen Consumption; Protein Kinase C; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase; Superoxides; Transcription Factor AP-1; Transcriptional Activation; Transfection; Vanadates | 1999 |
NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species.
Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Stability; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Multienzyme Complexes; NADP; Oxidative Stress; Proteasome Endopeptidase Complex; Reactive Oxygen Species | 1999 |
Glutathione and K(+) channel remodeling in postinfarction rat heart.
Topics: Acetylcysteine; Animals; Colorimetry; Electric Conductivity; Electrophysiology; Glucose; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Male; Myocardial Infarction; NADP; Oxidative Stress; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function | 2002 |
Apoptosis in mitotic competent undifferentiated cells is induced by cellular redox imbalance independent of reactive oxygen species production.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Differentiation; Cytochrome c Group; Dehydroepiandrosterone; Diamide; Drug Synergism; Enzyme Activation; Free Radical Scavengers; Glucose; Glutathione; Glutathione Disulfide; Kinetics; Mitosis; NADP; Oxidation-Reduction; PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species | 2002 |
Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells.
Topics: Acetylcysteine; Amidines; Catalase; Cell Survival; Cyclic N-Oxides; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Microscopy, Confocal; NADP; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; tert-Butylhydroperoxide; Time Factors; U937 Cells | 2002 |
AOPP-induced activation of human neutrophil and monocyte oxidative metabolism: a potential target for N-acetylcysteine treatment in dialysis patients.
Topics: Acetylcysteine; Blood Proteins; Dose-Response Relationship, Drug; Humans; Monocytes; NADP; Neutrophils; Oxidation-Reduction; Oxygen; Peroxidase; Platelet Activating Factor; Serum Albumin; Uremia | 2003 |
Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Arsenates; Arsenites; Biological Transport; Buthionine Sulfoximine; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Drug-Related Side Effects and Adverse Reactions; Endothelium, Vascular; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; NADP; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Thioredoxins | 2003 |
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2005 |
Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.
Topics: Acetylcysteine; ADP-ribosyl Cyclase 1; Animals; Calcium; Cyclic ADP-Ribose; Endoplasmic Reticulum; Erythromycin; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred ICR; Mice, Knockout; NADP; Signal Transduction | 2008 |
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxyglucose; Free Radical Scavengers; Glucose; Humans; Mice; Mice, Inbred Strains; NADP; Oxidative Stress; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Sulfhydryl Compounds | 2008 |
[Suppression of cell proliferation by inhibitors to redox signaling in human lens epithelial cells].
Topics: Acetylcysteine; Arachidonic Acids; Catalase; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Fibroblast Growth Factor 2; Humans; Lens, Crystalline; Male; NADP; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction | 2008 |
Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione.
Topics: Acetylcysteine; Biocatalysis; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glutathione; Glutathione Reductase; NADP; Thiocarbamates | 2009 |
Effects of glutathione reductase inhibition on cellular thiol redox state and related systems.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Disulfides; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione Disulfide; Glutathione Reductase; Intracellular Space; NAD; NADP; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates | 2009 |
Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Cardiovascular Agents; Cyclooctanes; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Female; Glutathione; Lignans; Microsomes; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NADP; Oxidation-Reduction; Phytotherapy; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Schisandra | 2010 |
Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes.
Topics: Acetylation; Acetylcysteine; Alcohol Dehydrogenase; Animals; Antioxidants; Cells, Cultured; Ethanol; Free Radical Scavengers; Glutathione; Hepatocytes; Histones; Hydrogen Peroxide; Lysine; Male; Mitochondria, Liver; NADP; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger | 2010 |
In vitro metabolism of oxymetazoline: evidence for bioactivation to a reactive metabolite.
Topics: Acetylcysteine; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Glutathione; Humans; Hydroxylation; In Vitro Techniques; Indolequinones; Liver; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxymetazoline; Rabbits; Rats; Sympathomimetics | 2011 |
Glutathione modulates the toxicity of, but is not a biologically relevant reductant for, the Pseudomonas aeruginosa redox toxin pyocyanin.
Topics: Acetylcysteine; Cell Division; Cells, Cultured; Cysteine; Electron Spin Resonance Spectroscopy; Glutathione; Humans; NADP; Oxidation-Reduction; Pseudomonas aeruginosa; Pyocyanine; Reactive Oxygen Species | 2011 |
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M).
Topics: Acetylcysteine; Antineoplastic Agents; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Microsomes, Liver; NADP; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sulfonamides | 2011 |
Genistein decreases cellular redox potential, partially suppresses cell growth in HL‑60 leukemia cells and sensitizes cells to γ‑radiation‑induced cell death.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation; Down-Regulation; G2 Phase; Gamma Rays; Genistein; HL-60 Cells; Humans; Isocitrate Dehydrogenase; Leukemia; Lymphocytes; NADP; Oxidation-Reduction; Reactive Oxygen Species; Up-Regulation | 2014 |
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Mice; NADP; Radiation Tolerance; Xenograft Model Antitumor Assays | 2017 |
Topics: Acetylcysteine; Acrolein; Animals; Carcinoma, Lewis Lung; Isocitrate Dehydrogenase; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NADP; Oxidation-Reduction; Oxidative Stress; RNA, Small Interfering | 2017 |
Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Male; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; NADP; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reactive Oxygen Species; Transcription Factors; Uncoupling Protein 3; Xanthine Oxidase | 2019 |
NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF-1α signaling in hepatocellular carcinoma.
Topics: Acetylcysteine; Analysis of Variance; Animals; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Disease-Free Survival; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Free Radical Scavengers; Heterografts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice; Middle Aged; NADP; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasm Transplantation; Oxidation-Reduction; Racemases and Epimerases; Reactive Oxygen Species; Risk Factors | 2021 |
Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli.
Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Deferoxamine; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Iron; NAD; NADP; Proteomics; Quinones; Reactive Oxygen Species; Siderophores; Sulfur | 2022 |
Oxidative Stress as a Contributor to Insulin Resistance in the Skeletal Muscles of Mice with Polycystic Ovary Syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Dehydroepiandrosterone; Female; Humans; Insulin Resistance; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NADP; Oxidative Stress; Oxidoreductases; Polycystic Ovary Syndrome; Reactive Oxygen Species; Receptors, Androgen; Testosterone | 2022 |