acetylcysteine and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

acetylcysteine has been researched along with n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Doroshow, JH1
Dear, J1
Ignarro, LJ; Jynge, P; Karlsson, JOG; Lundström, I1
Black, P; Dear, JW; Gallagher, B; Grahamslaw, J; Henriksen, D; Lee, RJ; Morrison, EE; O'Brien, R; Oatey, K; Oosthuyzen, W; Weir, CJ1
Karlsson, JOG1
Dear, JW1
Freeman, WE; Mullins, ME; Yeager, LH1
Akakpo, JY; Jaeschke, H; Ramachandran, A1

Reviews

2 review(s) available for acetylcysteine and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

ArticleYear
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate

2020
Novel strategies for the treatment of acetaminophen hepatotoxicity.
    Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate

2020

Trials

2 trial(s) available for acetylcysteine and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

ArticleYear
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi
    Trials, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design

2019
Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).
    EBioMedicine, 2019, Volume: 46

    Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult

2019

Other Studies

4 other study(ies) available for acetylcysteine and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

ArticleYear
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
    Journal of the National Cancer Institute, 2006, Feb-15, Volume: 98, Issue:4

    Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Edetic Acid; Humans; Hydrogen Peroxide; Leukocytes; Mice; Oxidation-Reduction; Pyridoxal Phosphate; Reactive Oxygen Species

2006
Letter in response to: "Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: stud
    Trials, 2019, 06-24, Volume: 20, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Drug Overdose; Edetic Acid; Humans; Pyridoxal Phosphate; Research Design

2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir?
    EBioMedicine, 2019, Volume: 47

    Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase

2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? - Authors' reply.
    EBioMedicine, 2019, Volume: 47

    Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase

2019