acetylcysteine and n-acetylcysteine lysinate

acetylcysteine has been researched along with n-acetylcysteine lysinate in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (26.67)18.2507
2000's14 (46.67)29.6817
2010's4 (13.33)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
App, EM; Coffiner, M; Fossion, J; King, M; Maes, P; Tomkiewicz, RP1
App, EM; Coffiner, M; De Sanctis, GT; King, M; Maes, P; Rubin, BK; Tomkiewicz, RP1
Dasgupta, B; King, M1
Maes, P; Nève, J; Vanderbist, F1
App, EM; Cantin, AM; Coffiner, M; Gillissen, A; Jaworska, M; Maes, P; Orth, M; Schultze-Werninghaus, G1
Gillissen, A1
Bartling, A; Gillissen, A; Schoen, S; Schultze-Werninghaus, G1
Moës, AJ; Moyano-Pavon, I; Vanderbist, F; Wery, B1
Baran, D; Moës, AJ; Schoutens, A; Van Gansbeke, B; Vanderbist, F; Wery, B1
Alton, EW; Colledge, WH; Evans, MJ; Farley, R; Ferrari, S; Geddes, DM; Kitson, C; Marriott, C; Parkins, DA; Scarpa, M; Steel, R; Wainwright, B1
App, EM; Baran, D; Coffiner, M; Dab, I; King, M; Malfroot, A; Vanderbist, F1
Antonicelli, F; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I1
De Wit, D; Goldman, M; Nève, J; Verhasselt, V; Vosters, O; Willems, F1
Borm, PJ; Brown, DM; Dehnhardt, M; Donaldson, K; Gilmour, P; Jimenez, LA; Schins, RP; Stone, V1
Becker, HH; Dopp, E; Lohani, M; Poser, I; Rahman, Q; Schiffmann, D; Weiss, DG; Yadav, S1
Antonicelli, F; Brown, D; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I1
Holland, SM; Kishida, KT; Klann, E; Pao, M1
Babar, S; Boudjeltia, KZ; Ducobu, J; Legssyer, I; Moguilevsky, N; Moreau, P; Nève, J; Van Antwerpen, P; Vanhaeverbeek, M1
Cao, H; Hu, J; Kushwah, R; Oliver, JR1
Alipour, M; Omri, A; Smith, MG; Suntres, ZE1
Beuneu, C; Goldman, M; Verhasselt, V; Vosters, O1
Bumke, MA; ElSohly, MA; Galal, AM; Gul, W; Han, B; Hollingshead, MG; Newton, DL; Slade, D; Stockwin, LH; Yu, SX1
Cosgarea, M; Maniu, A; Perde-Schrepler, M1
Bielefeld, EC; Chen, G; Henderson, D; Hu, B; Yang, W1
Barbanel, G; Billard, JM; Dutar, P; Haxaire, C; Kervern, M; Mothet, JP; Potier, B; Sinet, PM; Turpin, FR1
Alapinar, C; Debelec-Butuner, B; Erbaykent-Tepedelen, B; Gonen-Korkmaz, C; Hamid, SM; Korkmaz, KS; Varisli, L1
Chen, W; Chen, YH; Ruan, Q; Sun, H; Tang, A; Wan, X; Wang, J; Yan, D; Yang, X; Zamani, A; Zhang, H1
Baby, SM; Bates, JN; Gaston, B; Getsy, PM; Hsieh, YH; Lewis, SJ; Lewis, THJ; May, WJ1
Liang, X; Su, Z; Sun, D; Tu, M; Wang, Y; Xie, M; Zeng, R; Zhang, G1
Chen, J; Cheng, T; Guan, Y; Hao, Z; Liao, B; Liu, S; Shi, J; Tong, L; Weng, Y1

Reviews

1 review(s) available for acetylcysteine and n-acetylcysteine lysinate

ArticleYear
[New perspectives of antioxidant therapy with thiols: nacystelyn].
    Pneumologie (Stuttgart, Germany), 1996, Volume: 50 Suppl 3

    Topics: Acetylcysteine; Antioxidants; Cystic Fibrosis; Expectorants; Humans; Lysine; Prodrugs

1996

Trials

2 trial(s) available for acetylcysteine and n-acetylcysteine lysinate

ArticleYear
Deposition of nacystelyn from a dry powder inhaler in healthy volunteers and cystic fibrosis patients.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:3

    Topics: Absorption; Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Analysis of Variance; Child; Cystic Fibrosis; Expectorants; Female; Humans; Lung; Lysine; Male; Powders; Radionuclide Imaging; Technetium; Tissue Distribution

2001
Dose-finding and 24-h monitoring for efficacy and safety of aerosolized Nacystelyn in cystic fibrosis.
    The European respiratory journal, 2002, Volume: 19, Issue:2

    Topics: Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Aerosols; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Female; Humans; Lysine; Male; Nebulizers and Vaporizers; Respiratory Mechanics; Sputum; Viscosity

2002

Other Studies

27 other study(ies) available for acetylcysteine and n-acetylcysteine lysinate

ArticleYear
Mucolytic treatment with N-acetylcysteine L-lysinate metered dose inhaler in dogs: airway epithelial function changes.
    The European respiratory journal, 1994, Volume: 7, Issue:1

    Topics: Acetylcysteine; Animals; Bronchi; Dogs; Epithelium; In Vitro Techniques; Lysine; Mucociliary Clearance; Mucus; Nebulizers and Vaporizers; Rana pipiens; Rheology; Trachea

1994
A comparison of a new mucolytic N-acetylcysteine L-lysinate with N-acetylcysteine: airway epithelial function and mucus changes in dog.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:6

    Topics: Acetylcysteine; Administration, Inhalation; Animals; Bronchi; Dogs; Expectorants; Female; Lysine; Male; Mucociliary Clearance; Mucus; Trachea; Viscosity

1995
Reduction in viscoelasticity in cystic fibrosis sputum in vitro using combined treatment with nacystelyn and rhDNase.
    Pediatric pulmonology, 1996, Volume: 22, Issue:3

    Topics: Acetylcysteine; Adolescent; Adult; Cystic Fibrosis; Deoxyribonuclease I; Elasticity; Expectorants; Humans; In Vitro Techniques; Lysine; Recombinant Proteins; Rheology; Sputum; Viscosity

1996
In vitro comparative assessment of the antioxidant activity of nacystelyn against three reactive oxygen species.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Captopril; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Lysine; Reactive Oxygen Species

1996
Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro.
    Respiratory medicine, 1997, Volume: 91, Issue:3

    Topics: Acetylcysteine; Antioxidants; Cell-Free System; Cells, Cultured; Depression, Chemical; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Lysine; Neutrophils; Reactive Oxygen Species

1997
Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in vitro.
    Lung, 1997, Volume: 175, Issue:4

    Topics: Acetylcysteine; Adult; Ambroxol; Antioxidants; Catalase; Expectorants; Female; Free Radical Scavengers; Glutathione; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lysine; Male; Neutrophils; Reactive Oxygen Species; Superoxide Dismutase

1997
Optimization of a dry powder inhaler formulation of nacystelyn, a new mucoactive agent.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:11

    Topics: Acetylcysteine; Administration, Inhalation; Capsules; Drug Carriers; Expectorants; Hydrogen-Ion Concentration; Lactose; Lysine; Microscopy, Electron, Scanning; Particle Size; Powders; Solubility

1999
Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium.
    Gene therapy, 2001, Volume: 8, Issue:18

    Topics: Acetylcysteine; Animals; Chloramphenicol O-Acetyltransferase; Cholinergic Antagonists; Cystic Fibrosis; Dose-Response Relationship, Drug; Expectorants; Gene Expression; Genetic Therapy; Genetic Vectors; Glycopyrrolate; Injections, Intramuscular; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred CFTR; Models, Animal; Nasal Mucosa; Sheep; Trachea

2001
Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells.
    Free radical biology & medicine, 2002, Mar-15, Volume: 32, Issue:6

    Topics: Acetylcysteine; Binding Sites; Cell Line; Chemotaxis; Epithelial Cells; Humans; Hydrogen Peroxide; Interleukin-8; Lysine; NF-kappa B; Oxidants; Oxidation-Reduction; Pulmonary Alveoli; RNA, Messenger; Tumor Necrosis Factor-alpha

2002
Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory t cells.
    Transplantation, 2003, Feb-15, Volume: 75, Issue:3

    Topics: Acetylcysteine; Cell Differentiation; Cells, Cultured; Dendritic Cells; Flow Cytometry; Humans; Immune Tolerance; Lipopolysaccharides; Lysine; T-Lymphocytes; Transplantation Immunology; Transplantation, Homologous

2003
Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:2

    Topics: Acetylcysteine; Air Pollutants; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbon; Chelating Agents; Egtazic Acid; Gene Expression; Lysine; Macrophages, Alveolar; Male; Particle Size; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Verapamil

2004
Modulation of genotoxic effects in asbestos-exposed primary human mesothelial cells by radical scavengers, metal chelators and a glutathione precursor.
    Mutation research, 2004, Apr-11, Volume: 559, Issue:1-2

    Topics: Acetylcysteine; Asbestos, Crocidolite; Asbestos, Serpentine; Chelating Agents; Deferoxamine; Epithelial Cells; Free Radical Scavengers; Humans; Kinetochores; Lysine; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenesis; Phytic Acid; Superoxide Dismutase; Thiourea

2004
Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Chemotaxis; Cycloheximide; Enzyme Inhibitors; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Lipopolysaccharides; Lysine; Male; Monocytes; Neutrophils; Okadaic Acid; Pneumonia; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors

2004
NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1.
    Journal of neurochemistry, 2005, Volume: 94, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcysteine; Animals; Azoles; Blotting, Western; Catalase; Catecholamines; Dopamine Agonists; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Hippocampus; Imidazolines; In Vitro Techniques; Isoindoles; Lysine; Metalloporphyrins; Mice; Mice, Inbred C57BL; N-Methylaspartate; NADPH Oxidases; Neurons; NG-Nitroarginine Methyl Ester; Organoselenium Compounds; Patch-Clamp Techniques; Phosphorylation; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase

2005
Thiol-containing molecules interact with the myeloperoxidase/H2O2/chloride system to inhibit LDL oxidation.
    Biochemical and biophysical research communications, 2005, Nov-11, Volume: 337, Issue:1

    Topics: Acetylcysteine; Antioxidants; Captopril; Chlorides; Flufenamic Acid; Glutathione; Hydrogen Peroxide; Lipoproteins, LDL; Lysine; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds

2005
Nacystelyn enhances adenoviral vector-mediated gene delivery to mouse airways.
    Gene therapy, 2007, Volume: 14, Issue:16

    Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line; DEAE-Dextran; Expectorants; Gene Expression; Genetic Therapy; Genetic Vectors; Lac Operon; Lung; Lysine; Mice; Mice, Inbred C57BL; Staining and Labeling; Transduction, Genetic

2007
Prophylactic effect of liposomal N-acetylcysteine against LPS-induced liver injuries.
    Journal of endotoxin research, 2007, Volume: 13, Issue:5

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chloramines; Disease Models, Animal; Lipid Peroxidation; Lipopolysaccharides; Liver; Lysine; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

2007
N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells.
    Pancreas, 2008, Volume: 36, Issue:4

    Topics: Acetylcysteine; Adenocarcinoma; CD40 Antigens; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lysine; NF-kappa B; Pancreatic Ducts; Pancreatic Neoplasms; Transcription, Genetic

2008
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
    International journal of cancer, 2009, Sep-15, Volume: 125, Issue:6

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisia; Artemisinins; Biomarkers; Blotting, Western; Calcium; Cell Cycle; Dimerization; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Profiling; Heme; Heme Oxygenase-1; Humans; Lysine; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin

2009
Protective effect of L-N-acetylcysteine against gentamycin ototoxicity in the organ cultures of the rat cochlea.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2011, Volume: 52, Issue:1

    Topics: Acetylcysteine; Animals; Cochlea; Dissection; Gentamicins; Hair Cells, Auditory; Lysine; Organ Culture Techniques; Protective Agents; Rats

2011
[L-NAC protect hair cells in the rat cochlea from injury of exposure to styrene].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2011, Volume: 25, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cochlea; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory; Lysine; Rats; Rats, Long-Evans; Styrene

2011
Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
    Aging cell, 2012, Volume: 11, Issue:2

    Topics: Acetylcysteine; Aging; Animals; Hippocampus; Lysine; Male; Neuronal Plasticity; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine

2012
Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:2

    Topics: Acetylcysteine; Androgens; Antioxidants; Apoptosis; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Glutathione Peroxidase; Homeodomain Proteins; Humans; I-kappa B Proteins; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Kallikreins; Lysine; Macrophages; Male; Matrix Metalloproteinase 9; NF-kappa B; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatitis; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Receptors, Androgen; Signal Transduction; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation

2014
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis.
    The Journal of experimental medicine, 2020, 02-03, Volume: 217, Issue:2

    Topics: Acetylcysteine; Adoptive Transfer; Animals; Carcinogenesis; Cell Polarity; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myeloid Cells; Myeloid-Derived Suppressor Cells; Reactive Oxygen Species; Signal Transduction; Transfection

2020
L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Acetylcysteine; Analgesics, Opioid; Animals; Fentanyl; Humans; Lysine; Male; Pain; Rats; Rats, Sprague-Dawley

2022
Softness enhanced macrophage-mediated therapy of inhaled apoptotic-cell-inspired nanosystems for acute lung injury.
    Journal of nanobiotechnology, 2023, May-30, Volume: 21, Issue:1

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Lung; Macrophages; Mice

2023
Genome-wide identification of the NAC gene family and its functional analysis in Liriodendron.
    BMC plant biology, 2023, Sep-08, Volume: 23, Issue:1

    Topics: Acetylcysteine; Cell Nucleus; Cytoplasm; Liriodendron

2023