acetylcysteine and mustard gas

acetylcysteine has been researched along with mustard gas in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's12 (44.44)29.6817
2010's11 (40.74)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Becks, LL; Dabrowska, MI; Hinshaw, DB; Lelli, JL; Levee, MG1
Baeza-Squiban, A; Calvet, J; Marano, F; Rappeneau, S1
Atkins, KB; Hinshaw, DB; Hurley, LL; Lodhi, IJ1
Anderson, DR; Byers, SL; Vesely, KR1
Chatterjee, D; Das, SK; Mukherjee, S; Smith, MG2
Arfsten, DP; Bobb, AJ; Jederberg, WW1
Alaedini, F; Aslani, J; Eshraghi, M; Ghanei, M; Shohrati, M1
Flierl, MA; Hoesel, LM; McClintock, SD; Niederbichler, AD; Pianko, MJ; Reuben, JS; Rittirsch, D; Sarma, JV; Smith, M; Stone, W; Ward, PA; Yang, H1
Paromov, V; Qui, M; Smith, M; Stone, WL; Yang, H1
Alaeddini, F; Aslani, J; Ghaderi, S; Ghanei, M; Jafari, M; Shohrati, M1
Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M; Stone, WL1
Saberi, M; Zaree Mahmodabady, A1
Balszuweit, F; Bloch, W; Bölck, B; Dühr, S; Ibrahim, M; Kehe, K; Schwarz, J; Steinritz, D; Thiermann, H1
Agarwal, C; Agarwal, R; Day, BJ; Huang, J; Tewari-Singh, N; White, CW1
Fairhall, S; Jenner, J; Jugg, B; Mann, T; Perrott, R; Rutter, S; Salguero, J; Sciuto, AM; Shute, J; Smith, A1
Ghanei, M; Karimzadeh, I; Khalili, H; Saburi, A; Shohrati, M1
Balszuweit, F; Kehe, K; Menacher, G; Popp, T; Schmidt, A; Steinritz, D; Thiermann, H; Worek, F1
David, J; Dillman, JF; Hoard-Fruchey, H; Jenner, J; Jugg, BJ; Rothwell, C; Sciuto, AM1
Gudermann, T; John, H; Mückter, H; Popp, T; Schmidt, A; Siegert, M; Steinritz, D; Stenger, B; Thiermann, H; Tsoutsoulopoulos, A1
Abtahi, H; Foroumandi, M; Peiman, S; Safavi, E1
John, H; Kranawetvogl, A; Siegert, M; Thiermann, H1
Ghanei, M; Hashjin, MM; Panahi, Y; Rezaee, R; Sahebkar, A1
Almacioglu, M; Demirkasimoglu, M; Eyison, RK; Ivelik, K; Kenar, L; Kunak, ZI; Ortatatli, M; Sezigen, S1
Eghtedardoost, M; Ghanei, M; Ghavami, S; Ghazanfari, T; Hassan, ZM; Sadeghipour, A1
Sawyer, TW1
Aghamollaei, H; Haddadi, M; Karami, A; Sabzevare, M; Shahriary, A; Yazdani, F1

Reviews

5 review(s) available for acetylcysteine and mustard gas

ArticleYear
N-acetyl-L-Cysteine as prophylaxis against sulfur mustard.
    Military medicine, 2005, Volume: 170, Issue:1

    Topics: Acetylcysteine; Animals; Chemical Warfare Agents; Chemoprevention; Humans; Mustard Gas; Protective Agents; Safety

2005
Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Survival; Cells, Cultured; Dermatitis; DNA; Female; Glutathione; Humans; Mice; Mice, Hairless; Mustard Gas; Peroxidase; Skin; Skinfold Thickness

2011
The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review.
    Inhalation toxicology, 2014, Volume: 26, Issue:9

    Topics: Acetylcysteine; Animals; Bronchiolitis Obliterans; Chemical Warfare Agents; Disease Models, Animal; Humans; Lung; Mustard Gas; Oxidative Stress; Randomized Controlled Trials as Topic

2014
Potential Utility of N-acetylcysteine for Treating Mustard Lung.
    Critical reviews in eukaryotic gene expression, 2017, Volume: 27, Issue:3

    Topics: Acetylcysteine; Apoptosis; Chemical Warfare Agents; Humans; Inflammation; Lung; Lung Diseases; Mustard Gas; Oxidative Stress

2017
N-Acetylcysteine as a treatment for sulphur mustard poisoning.
    Free radical biology & medicine, 2020, Volume: 161

    Topics: Acetylcysteine; Chemical Warfare Agents; Glutathione; Humans; Iran; Mustard Gas

2020

Trials

2 trial(s) available for acetylcysteine and mustard gas

ArticleYear
Therapeutics effect of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test.
    Respiratory medicine, 2008, Volume: 102, Issue:3

    Topics: Acetylcysteine; Antioxidants; Bronchiolitis Obliterans; Chemical Warfare Agents; Double-Blind Method; Female; Forced Expiratory Volume; Free Radical Scavengers; Free Radicals; Humans; Male; Middle Aged; Mustard Gas; Treatment Outcome; Vital Capacity

2008
N-acetylcysteine improves the clinical conditions of mustard gas-exposed patients with normal pulmonary function test.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:5

    Topics: Acetylcysteine; Adult; Antioxidants; Bronchiolitis Obliterans; Chemical Warfare Agents; Double-Blind Method; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Middle Aged; Mustard Gas; Oxidative Stress; Respiratory Function Tests; Spirometry; Sputum; Time Factors; Vital Capacity

2008

Other Studies

20 other study(ies) available for acetylcysteine and mustard gas

ArticleYear
Sulfur mustard induces apoptosis and necrosis in endothelial cells.
    Toxicology and applied pharmacology, 1996, Volume: 141, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Apoptosis; Cattle; Cell Adhesion; Cells, Cultured; Chemical Warfare Agents; Cytoskeleton; Dose-Response Relationship, Drug; Endothelium, Vascular; GTP-Binding Proteins; Microtubules; Mustard Gas; Necrosis

1996
Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Acetylcysteine; Bronchi; Cells, Cultured; Citrulline; Cytoprotection; Dose-Response Relationship, Drug; Doxycycline; Drug Combinations; Drug Interactions; Epithelial Cells; Humans; Mechlorethamine; Mercaptoethylamines; Methenamine; Mustard Gas; NG-Nitroarginine Methyl Ester; Niacinamide; Protective Agents; Radiation-Protective Agents; Tetrazolium Salts; Thiourea

2000
N-acetylcysteine and endothelial cell injury by sulfur mustard.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Acetylcysteine; Animals; Apoptosis; Cattle; Cytokines; Dermatologic Agents; Endothelium; Gene Expression Regulation; Glutathione; Inflammation; Mustard Gas; NF-kappa B

2000
Treatment of sulfur mustard (HD)-induced lung injury.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage; Dermatologic Agents; Free Radical Scavengers; gamma-Glutamyltransferase; Lung; Lung Diseases; Male; Mustard Gas; Neutrophils; Niacinamide; Rats

2000
Prophylactic protection by N-acetylcysteine against the pulmonary injury induced by 2-chloroethyl ethyl sulfide, a mustard analogue.
    Journal of biochemical and molecular toxicology, 2003, Volume: 17, Issue:3

    Topics: Acetylcysteine; Animals; Caspases; Ceramides; Electrophoretic Mobility Shift Assay; Free Radical Scavengers; Free Radicals; Guinea Pigs; Lung; Lung Diseases; Male; Mustard Gas; NF-kappa B; Sphingomyelin Phosphodiesterase; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2003
Evidence of hair loss after subacute exposure to 2-chloroethyl ethyl sulfide, a mustard analog, and beneficial effects of N-acetyl cysteine.
    Journal of biochemical and molecular toxicology, 2004, Volume: 18, Issue:3

    Topics: Acetylcysteine; Alopecia; Animals; Biomarkers; Guinea Pigs; Hair; Mustard Gas; Toxicity Tests, Acute

2004
Ability of antioxidant liposomes to prevent acute and progressive pulmonary injury.
    Antioxidants & redox signaling, 2008, Volume: 10, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Free Radical Scavengers; Humans; Liposomes; Lung; Macrophages, Alveolar; Male; Mustard Gas; Rats; Rats, Long-Evans; Respiratory Distress Syndrome; Tocopherols

2008
The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue.
    BMC cell biology, 2008, Jun-20, Volume: 9

    Topics: Acetylcysteine; Animals; Cell Survival; Free Radical Scavengers; Glutathione; Lipopolysaccharides; Macrophages; Mice; Microscopy, Fluorescence; Mustard Gas; Nitric Oxide; Oxidative Stress; Polymyxin B

2008
Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
    Toxicology, 2009, Jul-10, Volume: 261, Issue:3

    Topics: Acetylcysteine; Activating Transcription Factors; Animals; Antidotes; Antioxidants; Blood Proteins; Cell Proliferation; Cyclin D1; Disease Models, Animal; Erythrocytes; Guinea Pigs; Liposomes; Lung; Lung Injury; Male; Mitogen-Activated Protein Kinases; Mustard Gas; Neutrophil Infiltration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pulmonary Eosinophilia; Time Factors; Tocopherols; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2009
The protective effects of N-Acetl-cysteine, oxo-thiazolidine-carboxylate, acetaminophen and their combinations against sulfur mustard cytotoxicity on human skin fibroblast cell line (HF2FF).
    Iranian biomedical journal, 2009, Volume: 13, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Catalase; Cell Line; Cell Survival; Chemical Warfare Agents; Cytoprotection; Drug Interactions; Fibroblasts; Free Radical Scavengers; Glutathione; Humans; Mustard Gas; Pyrrolidonecarboxylic Acid; Skin; Thiazolidines

2009
Effect of N-acetyl cysteine and alpha-linolenic acid on sulfur mustard caused impairment of in vitro endothelial tube formation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Acetylcysteine; alpha-Linolenic Acid; Animals; Apoptosis; Caspase 3; Cell Proliferation; Cells, Cultured; Chemical Warfare Agents; Drug Administration Schedule; Embryoid Bodies; Endothelial Cells; Free Radical Scavengers; Ki-67 Antigen; Mice; Mustard Gas; Neovascularization, Physiologic; Platelet Endothelial Cell Adhesion Molecule-1; Time Factors; Wound Healing

2010
N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:4

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Animals; Antidotes; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; Expectorants; Female; Gas Poisoning; Lung; Lung Diseases; Mustard Gas; Neutrophil Infiltration; Random Allocation; Respiratory Insufficiency; Survival Analysis; Sus scrofa

2013
Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line.
    Toxicology letters, 2016, Feb-26, Volume: 244

    Topics: Acetylcysteine; Antidotes; Apoptosis; Cell Line; Chemical Warfare Agents; Cytoprotection; Dose-Response Relationship, Drug; Glutathione; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Keratinocytes; Mustard Gas; Necrosis; Sulfhydryl Compounds; Time Factors

2016
Acute Gene Expression Profile of Lung Tissue Following Sulfur Mustard Inhalation Exposure in Large Anesthetized Swine.
    Chemical research in toxicology, 2016, 10-17, Volume: 29, Issue:10

    Topics: Acetylcysteine; Administration, Inhalation; Anesthesia; Animals; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Inhalation Exposure; Lung; Models, Animal; Mustard Gas; Swine; Toxicity Tests

2016
N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx.
    Archives of toxicology, 2017, Volume: 91, Issue:5

    Topics: Acetylcysteine; Antioxidants; Calcium; Chemical Warfare Agents; Dose-Response Relationship, Drug; Glutathione; HEK293 Cells; Humans; Mustard Gas; Oximes; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; TRPA1 Cation Channel

2017
Long Term Follow-Up of Sulfur Mustard Related Bronchiolitis Obliterans Treatment.
    Acta medica Iranica, 2016, Volume: 54, Issue:9

    Topics: Acetylcysteine; Adult; Asthma; Bronchiolitis Obliterans; Follow-Up Studies; Humans; Lung; Male; Middle Aged; Mustard Gas; Retrospective Studies; Spirometry

2016
N-Acetylcysteine as a chemical scavenger for sulfur mustard: New insights by mass spectrometry.
    Drug testing and analysis, 2018, Volume: 10, Issue:2

    Topics: Acetylcysteine; Alkylation; Antidotes; Chromatography, Liquid; Kinetics; Mustard Gas; Proteolysis; Serum Albumin, Human; Tandem Mass Spectrometry

2018
Victims of chemical terrorism, a family of four who were exposed to sulfur mustard.
    Toxicology letters, 2019, Mar-15, Volume: 303

    Topics: Acetaminophen; Acetylcysteine; Administration, Cutaneous; Administration, Inhalation; Adult; Albuterol; Asian People; Chemical Terrorism; Child, Preschool; Cyclopentolate; Female; Gentamicins; Humans; Infant, Newborn; Lidocaine; Male; Methylprednisolone; Mustard Gas; Silver Sulfadiazine; Skin; Syria; Terrorism; Turkey

2019
Delayed effects of sulfur mustard on autophagy suppression in chemically-injured lung tissue.
    International immunopharmacology, 2020, Volume: 80

    Topics: Acetylcysteine; Adult; Albuterol; Armed Conflicts; Autophagy; Beclin-1; Case-Control Studies; Chemical Warfare Agents; Down-Regulation; Female; Humans; Iran; Lung; Lung Injury; Male; Microtubule-Associated Proteins; Middle Aged; Military Personnel; Mustard Gas; Oxidative Stress; Time Factors

2020
The effect of
    Immunopharmacology and immunotoxicology, 2021, Volume: 43, Issue:4

    Topics: Acetylcysteine; Angiogenesis Inducing Agents; Animals; Cornea; Doxycycline; Inflammation Mediators; Male; Mustard Gas; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2021