acetylcysteine and morphine

acetylcysteine has been researched along with morphine in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (35.14)	18.7374
1990's	2 (5.41)	18.2507
2000's	11 (29.73)	29.6817
2010's	10 (27.03)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Schreiber, EC	1
Beltrame, JF; Brennan, RJ; Horowitz, JD; Hunt, A; Moran, JL; Unger, SA; Zeitz, CJ	1
Cadet, P; Goumon, Y; Hempelmann, G; Hughes, TK; Menges, T; Menzebach, A; Stefano, GB; Welters, ID	1
Beebe, SJ; Hargrave, BY; Lattanzio, FA; Tiangco, DA	1
Choi, DH; Jung, EB; Kim, MS; Kim, TY; Lee, J; Moon, SK; Park, C; Park, R	1
Beheshtian, A; Dehpour, AR; Ghahremani, MH; Kiumehr, S; Payabvash, S; Sabzevari, O; Salmasi, AH; Tavangar, SM	1
Chi, ZQ; Ju, YW; Li, Q; Lin, X; Liu, JG; Wang, MW; Wang, YJ	1
Cechinel-Filho, V; Gurgel, LA; Lima-Júnior, RC; Martins, DT; Rao, VS; Santos, FA	1
Lim, G; Mao, J; Sung, B; Wang, S; Yang, L	1
Coderre, TJ; Laferrière, A; Nguyen, TM; Poon, AW; Saray, A; Schiller, PW	1
Saadat, I; Saadat, M; Saify, K	1
Haghparast, A; Katebi, SN; Riahi, E; Torkaman-Boutorabi, A; Vousooghi, N	1
Landman, ME; Spiro, RK	1
Breslow, L; Ingal, D; Perman, J	1
Gray, S; Langer, JC; Paes, BM	1
Eichler, I; Götz, M; Wagner, U	1
Belloli, G; Campobasso, P; Frigiola, S; Musi, L; Roberto, N	1
Kalayoglu, M; Kiesewetter, WB; Rodnan, JB; Sieber, WK	1
Shaw, A	1
Willital, GH	1
Burgert, EO; Lynn, HB; Simpson, TE	1
Hsia, DY; O'Flynn, M; Rowley, WF	1
Docter, JM; Eidelman, S; Lillibridge, CB	1
LYNN, HB	1
MEEKER, IA	1
Emil, S	1
Cohen, R; Cooke, A; Deshpande, AV; Wong, CK	1
Cober, MP; Fohl, AL; Johnson, CE	1
Calkovska, A; Drgova, A; Kopincova, J; Mokra, D; Pullmann, R	1
Calkovska, A; Drgova, A; Mokra, D; Mokry, J; Pistekova, H; Tonhajzerova, I; Visnovcova, Z	1
Antosova, M; Calkovska, A; Drgova, A; Mokra, D; Mokry, J; Petras, M	1
Antosova, M; Calkovska, A; Drgova, A; Durdik, P; Mokra, D; Mokry, J	1
Cheon, JE; Cho, HH; Choi, JH; Choi, YH; Kim, EK; Kim, HS; Kim, IO; Kim, WS; Lee, SM; Shin, SM; You, SK	1

Reviews

3 review(s) available for acetylcysteine and morphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Metabolically oxygenated compounds: formation, conjugation, and possible biological implications. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:8 Topics: Acetylcysteine; Alcohols; Animals; Biotransformation; Ethers, Cyclic; Glucuronates; Half-Life; Humans; Hydro-Lyases; Hydroxylation; Mixed Function Oxygenases; Morphine; Mutation; Neoplasms; Nitrogen; Oxides; Oxygen Consumption; Oxygenases; Pharmaceutical Preparations; Phenols; Phenylacetates; Species Specificity; Sulfates; Uracil Nucleotides	1974
Meconium ileus: a critical review of treatment and eventual prognosis. Journal of pediatric surgery, 1971, Volume: 6, Issue:3 Topics: Acetylcysteine; Adolescent; Autopsy; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Hydrogen Peroxide; Ileum; Infant; Infant, Newborn; Intestinal Obstruction; Intestinal Perforation; Intestine, Small; Male; Meconium; Pancreatin; Peritonitis; Prognosis; Radiography, Abdominal; Therapeutic Irrigation; Vitamin K Deficiency	1971

Trials

1 trial(s) available for acetylcysteine and morphine

Article	Year
Nitrate therapy is an alternative to furosemide/morphine therapy in the management of acute cardiogenic pulmonary edema. Journal of cardiac failure, 1998, Volume: 4, Issue:4 Topics: Acetylcysteine; Acute Disease; Diuretics; Drug Tolerance; Female; Free Radical Scavengers; Furosemide; Humans; Male; Morphine; Nitroglycerin; Prospective Studies; Pulmonary Edema; Treatment Outcome	1998

Other Studies

33 other study(ies) available for acetylcysteine and morphine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Morphine inhibits NF-kappaB nuclear binding in human neutrophils and monocytes by a nitric oxide-dependent mechanism. Anesthesiology, 2000, Volume: 92, Issue:6 Topics: Acetylcysteine; Analgesics, Opioid; Cell Nucleus; Enzyme Inhibitors; Flow Cytometry; Humans; In Vitro Techniques; Lipopolysaccharides; Male; Monocytes; Morphine; Naloxone; Narcotic Antagonists; Neutrophils; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Binding; Receptors, Opioid, mu	2000
Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kappaB in transiently cotransfected heart cells. Cardiovascular toxicology, 2003, Volume: 3, Issue:2 Topics: Acetylcysteine; Animals; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Free Radicals; Genes, Reporter; Glutathione; Morphine; Myocytes, Cardiac; Narcotics; NF-kappa B; Rats; Reactive Oxygen Species; Signal Transduction; Thioctic Acid; Transfection	2003
Morphine prevents glutamate-induced death of primary rat neonatal astrocytes through modulation of intracellular redox. Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:1 Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Astrocytes; Benzeneacetamides; Benzimidazoles; Bisbenzimidazole; Carbocyanines; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Glutamic Acid; Glutathione; Hydrogen Peroxide; Ion Channels; Microscopy, Fluorescence; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Morphine; Naloxone; Narcotic Antagonists; Neuroglia; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123	2004
Chronic morphine treatment induces oxidant and apoptotic damage in the mice liver. Life sciences, 2006, Aug-01, Volume: 79, Issue:10 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Survival; Chronic Disease; Glutathione; Liver; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Oxidative Stress; Pain; Signal Transduction	2006
Morphine inhibits doxorubicin-induced reactive oxygen species generation and nuclear factor kappaB transcriptional activation in neuroblastoma SH-SY5Y cells. The Biochemical journal, 2007, Sep-01, Volume: 406, Issue:2 Topics: Acetylcysteine; Apoptosis; Caspase 3; Cell Line, Tumor; Cytochromes c; Cytoprotection; Doxorubicin; Enzyme Activation; Humans; I-kappa B Kinase; Morphine; Neuroblastoma; NF-kappa B; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Transcriptional Activation	2007
Dragon's blood from Croton urucurana (Baill.) attenuates visceral nociception in mice. Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2 Topics: Abdominal Pain; Acetylcysteine; Administration, Oral; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Capsaicin; Clonidine; Croton; Cyclophosphamide; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Pentobarbital; Plant Extracts; Sleep; Time Factors	2007
Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation. The Journal of biological chemistry, 2008, Aug-01, Volume: 283, Issue:31 Topics: Acetylcysteine; Amino Acid Transport System X-AG; Analgesics, Opioid; Animals; Chloroquine; Excitatory Amino Acid Transporter 3; Humans; Leupeptins; Male; Morphine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitin	2008
The bifunctional μ opioid agonist/antioxidant [Dmt(1)]DALDA is a superior analgesic in an animal model of complex regional pain syndrome-type i. ACS chemical neuroscience, 2015, Nov-18, Volume: 6, Issue:11 Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antioxidants; Area Under Curve; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Hot Temperature; Hyperalgesia; Male; Morphine; Oligopeptides; Rats, Long-Evans; Receptors, Opioid, mu; Reflex Sympathetic Dystrophy; Touch	2015
Down-regulation of antioxidant genes in human SH-SY5Y cells after treatment with morphine. Life sciences, 2016, Jan-01, Volume: 144 Topics: Acetylcysteine; Analgesics, Opioid; Antioxidants; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Morphine; Reactive Oxygen Species; RNA, Messenger	2016
Systemic administration of N-acetylcysteine during the extinction period and on the reinstatement day decreased the maintenance of morphine rewarding properties in the rats. Behavioural brain research, 2021, 09-10, Volume: 413 Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Conditioning, Classical; Disease Models, Animal; Locomotion; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reinforcement, Psychology; Reward	2021
Meconium ileus equivalent. The American journal of gastroenterology, 1978, Volume: 69, Issue:3 Pt 1 Topics: Acetylcysteine; Adolescent; Adult; Age Factors; Child; Child, Preschool; Cystic Fibrosis; Fecal Impaction; Humans; Ileum; Infant; Infant, Newborn; Intestinal Obstruction; Male; Meconium; Radiography; Respiration, Artificial	1978
Nonoperative treatment of meconium ileus equivalent. American journal of diseases of children (1960), 1975, Volume: 129, Issue:10 Topics: Acetylcysteine; Child; Cystic Fibrosis; Enema; Feces; Female; Humans; Intestinal Obstruction; Lipase; Meconium	1975
Hypernatremia associated with N-acetylcysteine therapy for meconium ileus in a premature infant. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1990, Aug-01, Volume: 143, Issue:3 Topics: Acetylcysteine; Female; Humans; Hypernatremia; Infant, Newborn; Infant, Premature, Diseases; Intestinal Obstruction; Meconium	1990
[Gastrointestinal complications in cystic fibrosis: meconium ileus equivalent]. Padiatrie und Padologie, 1986, Volume: 21, Issue:2 Topics: Acetylcysteine; Adolescent; Child; Child, Preschool; Cystic Fibrosis; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Ileal Diseases; Intestinal Obstruction; Male; Meconium; Recurrence	1986
[Diagnostic and therapeutic possibilities and limitations of enemas with Gastrografin in meconium ileus]. La Pediatria, 1972, Volume: 80, Issue:4 Topics: Acetylcysteine; Amino Sugars; Diatrizoate; Enema; Humans; Infant, Newborn; Intestinal Obstruction; Male; Meconium; Radiography; Sorbitol	1972
Safety of N-acetylcysteine in treatment of meconium obstruction of the newborn. Journal of pediatric surgery, 1969, Volume: 4, Issue:1 Topics: Acetylcysteine; Animals; Dogs; Fecal Impaction; Gastrointestinal Hemorrhage; Humans; Hydrogen Peroxide; Hyperemia; Infant, Newborn; Infant, Newborn, Diseases; Meconium; Viscosity	1969
[Meconium ileus]. Munchener medizinische Wochenschrift (1950), 1970, Nov-13, Volume: 112, Issue:46 Topics: Acetylcysteine; Humans; Infant, Newborn; Intestinal Obstruction; Meconium; Methods	1970
Nonoperative treatment of meconium ileus: report of a case. Mayo Clinic proceedings, 1968, Volume: 43, Issue:10 Topics: Acetylcysteine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Intubation, Gastrointestinal; Meconium; Radiography	1968
Cystic fibrosis of the pancreas. Advances in cardiopulmonary diseases, 1966, Volume: 3 Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Child; Cystic Fibrosis; Digestive System; Drainage; Fecal Impaction; Humans; Hyperglycemia; Intestinal Obstruction; Liver Cirrhosis; Lung; Lung Diseases; Meconium; Mucus; Pneumatosis Cystoides Intestinalis; Respiratory Function Tests; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Diseases; Salivary Glands; Sweat	1966
Oral administration of n-acetyl cysteine in the prophylaxis of "meconium ileus equivalent". The Journal of pediatrics, 1967, Volume: 71, Issue:6 Topics: Acetylcysteine; Adult; Cystic Fibrosis; Enema; Humans; Intestinal Obstruction; Male; Meconium; Mucus; Pancreas; Pharmaceutical Vehicles	1967
MECONIUM ILEUS. The American surgeon, 1964, Volume: 30 Topics: Acetylcysteine; Child; Cysteine; Cystic Fibrosis; Diagnosis; Humans; Ileus; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Intussusception; Meconium; Pancreatic Extracts; Rectal Prolapse; Surgical Procedures, Operative	1964
ACETYLCYSTEINE USED TO LIQUEFY INSPISSATED MECONIUM CAUSING INTESTINAL OBSTRUCTION IN THE NEWBORN. Surgery, 1964, Volume: 56 Topics: Acetylcysteine; Cysteine; Cystic Fibrosis; Fetal Diseases; Hernia, Umbilical; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Intestinal Perforation; Meconium; Peritonitis; Surgical Procedures, Operative	1964
Meconium obstruction in the very low birth weight premature infant. Pediatrics, 2004, Volume: 114, Issue:5 Topics: Acetylcysteine; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Intestinal Obstruction; Intestinal Perforation; Intussusception; Meconium; Risk Factors	2004
Hepatic derangement following N-Acetylcysteine enemas in an infant with cystic fibrosis. Journal of paediatrics and child health, 2008, Volume: 44, Issue:11 Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Cystic Fibrosis; Enema; Fecal Impaction; Free Radical Scavengers; Humans; Ileus; Infant, Newborn; Meconium	2008
Stability of extemporaneously prepared acetylcysteine 1% and 10% solutions for treatment of meconium ileus. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, Jan-01, Volume: 68, Issue:1 Topics: Acetylcysteine; Administration, Oral; Chromatography, High Pressure Liquid; Drug Stability; Humans; Ileus; Infant, Newborn; Infant, Newborn, Diseases; Meconium; Solutions	2011
Anti-inflammatory treatment in dysfunction of pulmonary surfactant in meconium-induced acute lung injury. Advances in experimental medicine and biology, 2013, Volume: 756 Topics: Acetylcysteine; Acute Lung Injury; Aminophylline; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Budesonide; Dexamethasone; Disease Models, Animal; Humans; Imidazoles; Infant, Newborn; Leukocyte Count; Lung; Meconium; Meconium Aspiration Syndrome; Neutrophils; Oxidative Stress; Phosphodiesterase Inhibitors; Pulmonary Edema; Pulmonary Surfactants; Pyridones; Rabbits	2013
Cardiovascular effects of N-acetylcysteine in meconium-induced acute lung injury. Advances in experimental medicine and biology, 2015, Volume: 832 Topics: Acetylcysteine; Acute Lung Injury; Aldosterone; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Heart Rate; Humans; Infant, Newborn; Injections, Intravenous; Intubation, Intratracheal; Lung; Meconium; Meconium Aspiration Syndrome; Oxidative Stress; Rabbits; Respiration, Artificial; Thiobarbituric Acid Reactive Substances	2015
N-acetylcysteine alleviates the meconium-induced acute lung injury. Advances in experimental medicine and biology, 2015, Volume: 832 Topics: Acetylcysteine; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Infant, Newborn; Injections, Intravenous; Intubation, Intratracheal; Leukocyte Count; Lipid Peroxidation; Lung; Meconium; Meconium Aspiration Syndrome; Oxidative Stress; Pulmonary Edema; Rabbits; Respiration, Artificial; Thiobarbituric Acid Reactive Substances; Trachea	2015
N-acetylcysteine effectively diminished meconium-induced oxidative stress in adult rabbits. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2015, Volume: 66, Issue:1 Topics: Acetylcysteine; Age Factors; Animals; Antioxidants; Biomarkers; Disease Models, Animal; Humans; Infant, Newborn; Inflammation Mediators; Leukocytes; Lipid Peroxidation; Lung; Lung Injury; Meconium; Meconium Aspiration Syndrome; Mitochondria; Oxidative Stress; Pneumonia; Pulmonary Edema; Rabbits; Thiobarbituric Acid Reactive Substances; Time Factors	2015
Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success. European journal of radiology, 2015, Volume: 84, Issue:10 Topics: Acetylcysteine; Birth Weight; Cathartics; Contrast Media; Diatrizoate Meglumine; Enema; Expectorants; Female; Gestational Age; Humans; Ileal Diseases; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intestinal Obstruction; Intestinal Perforation; Iothalamic Acid; Male; Meconium; Radiography; Retreatment; Sodium Chloride; Time Factors; Treatment Outcome; Ultrasonography, Interventional	2015