Compounds > acetylcysteine

acetylcysteine and mitoxantrone

acetylcysteine has been researched along with mitoxantrone in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (63.64)	29.6817
2010's	3 (27.27)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Dai, W; Darzynkiewicz, Z; Huang, X; Kurose, A; Tanaka, T; Traganos, F	1
Banerji, S; Los, M	1
Bougnoux, P; Chourpa, I; Dubois, P; Goré, J; Mahéo, K; Vibet, S	1
Darzynkiewicz, Z; Halicka, HD; Seiter, K; Tanaka, T; Traganos, F	1
Arnold, M; Bissinger, R; Lang, F	1

Reviews

1 review(s) available for acetylcysteine and mitoxantrone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

10 other study(ies) available for acetylcysteine and mitoxantrone

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine. Cancer biology & therapy, 2006, Volume: 5, Issue:8 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; DNA Damage; DNA-Binding Proteins; Flow Cytometry; Fluorescent Antibody Technique; Histones; HL-60 Cells; Humans; Lung Neoplasms; Mitoxantrone; Phosphorylation; Protein Serine-Threonine Kinases; Topotecan; Tumor Cells, Cultured; Tumor Suppressor Proteins	2006
Important differences between topoisomerase-I and -II targeting agents. Cancer biology & therapy, 2006, Volume: 5, Issue:8 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Damage; DNA-Binding Proteins; Histones; Humans; Mitoxantrone; Phosphorylation; Protein Serine-Threonine Kinases; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured; Tumor Suppressor Proteins	2006
Differential subcellular distribution of mitoxantrone in relation to chemosensitization in two human breast cancer cell lines. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:5 Topics: Acetylcysteine; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Survival; Cytosol; Docosahexaenoic Acids; Female; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Microscopy, Confocal; Mitoxantrone; Molecular Structure; Reactive Oxygen Species; Rhodamine 123; Time Factors	2007
Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase. Cell cycle (Georgetown, Tex.), 2007, Feb-01, Volume: 6, Issue:3 Topics: Acetylcysteine; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line; DNA Damage; DNA Replication; DNA-Binding Proteins; Etoposide; Flow Cytometry; Free Radical Scavengers; G1 Phase; Histones; Humans; Immunohistochemistry; Mitoxantrone; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Suppressor Proteins	2007
Mitoxantrone-induced suicidal erythrocyte death. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 34, Issue:5 Topics: Acetylcysteine; Annexin A5; Apoptosis; Calcium; Cell Death; Cell Membrane; Cell Size; Ceramides; Erythrocytes; Fluoresceins; Humans; Mitoxantrone; Multiple Sclerosis; Oxidative Stress; Phosphatidylserines; Reactive Oxygen Species	2014