acetylcysteine and minocycline

acetylcysteine has been researched along with minocycline in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (36.36)29.6817
2010's11 (50.00)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cheema, SS; Lopes, EC; Turner, BJ1
Aslam, S; Darouiche, RO; Ramanathan, V; Trautner, BW2
Ahn, TB; Jeon, BS; Kwon, SJ; Yoon, MY1
Basu, A; Duseja, R; Ghosh, D; Mishra, MK1
Mannargudi, B; McNally, D; Reynolds, W; Uetrecht, J1
Abdel Baki, SG; Bergold, PJ; Fenton, AA; Haber, M; Schwab, B1
Aslam, S; Darouiche, RO1
Butterworth, RF1
Abdel Baki, SG; Bergold, PJ; Dash, P; Ershova, A; Grill, RJ; Grin'kina, NM; Haber, M; Irizarry, R; Orsi, S1
Bergold, PJ; Grin'kina, NM; Haber, M; Hartman, I; Ho, J; Irizarry, R; James, J; Kim, J; Nikulina, E; Ramadani, A; Sangobowale, M1
Kimmitt, BA; Moore, GE; Stiles, J1
Bergold, PJ; Nikulina, E; Sangobowale, M1
Domoto, R; Kawabata, A; Nakashima, K; Nishibori, M; Sekiguchi, F; Tsubota, M; Wake, H; Yamanishi, H; Yamasoba, D1
Koola, MM1
Alexis, A; Bergold, PJ; Nikulina, E; Rahman, SN; Whitney, K1
Bahcivan, E; Dik, B; Eser Faki, H; Ozdemir Kutahya, Z; Tras, B; Uney, K1
Arteaga-HenrĂ­quez, G; Gisbert, L; Ramos-Quiroga, JA1

Reviews

3 review(s) available for acetylcysteine and minocycline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hepatic encephalopathy: a central neuroinflammatory disorder?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Animals; Brain Edema; Hepatic Encephalopathy; Humans; Hypothermia, Induced; Liver Failure, Acute; Minocycline

2011
Immunoregulatory and/or Anti-inflammatory Agents for the Management of Core and Associated Symptoms in Individuals with Autism Spectrum Disorder: A Narrative Review of Randomized, Placebo-Controlled Trials.
    CNS drugs, 2023, Volume: 37, Issue:3

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Autism Spectrum Disorder; Celecoxib; Fatty Acids, Omega-3; Humans; Immunologic Factors; Minocycline; Prednisolone; Randomized Controlled Trials as Topic

2023

Trials

1 trial(s) available for acetylcysteine and minocycline

ArticleYear
Pilot trial of N-acetylcysteine and tigecycline as a catheter-lock solution for treatment of hemodialysis catheter-associated bacteremia.
    Infection control and hospital epidemiology, 2008, Volume: 29, Issue:9

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bacteremia; Catheterization; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Minocycline; Pilot Projects; Prospective Studies; Renal Dialysis; Tigecycline; Treatment Outcome

2008

Other Studies

18 other study(ies) available for acetylcysteine and minocycline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
    Journal of cellular biochemistry, 2004, Apr-01, Volume: 91, Issue:5

    Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Chelating Agents; Chlorides; Copper; Detergents; Disease Models, Animal; Ditiocarb; Fibroblasts; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Minocycline; Mutation; Oxidative Stress; Paraquat; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds

2004
Combination of tigecycline and N-acetylcysteine reduces biofilm-embedded bacteria on vascular catheters.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bacteria; Biofilms; Catheterization, Central Venous; Catheters, Indwelling; Drug Combinations; Drug Resistance, Bacterial; Equipment Contamination; Minocycline; Staphylococcus aureus; Staphylococcus epidermidis; Tigecycline

2007
BV-2 stimulation by lactacystin results in a strong inflammatory reaction and apoptotic neuronal death in SH-SY5Y cells.
    Brain research, 2008, Apr-18, Volume: 1205

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Apoptosis; Cell Line; Cell Survival; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; I-kappa B Proteins; Inflammation; Macrophage Activation; Mice; Microglia; Minocycline; Neurons; NF-KappaB Inhibitor alpha; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Proteasome Endopeptidase Complex

2008
Antioxidant potential of Minocycline in Japanese Encephalitis Virus infection in murine neuroblastoma cells: correlation with membrane fluidity and cell death.
    Neurochemistry international, 2009, Volume: 54, Issue:7

    Topics: Acetylcysteine; Animals; Anisotropy; Anti-Bacterial Agents; Antioxidants; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Encephalitis, Japanese; Enzyme Inhibitors; Free Radicals; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Membrane Fluidity; Membrane Potentials; Mice; Mice, Inbred BALB C; Minocycline; Mitochondrial Membranes; Neuroblastoma; Onium Compounds; Reactive Oxygen Species

2009
Bioactivation of minocycline to reactive intermediates by myeloperoxidase, horseradish peroxidase, and hepatic microsomes: implications for minocycline-induced lupus and hepatitis.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:9

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Biotransformation; Chromatography, High Pressure Liquid; Free Radical Scavengers; Free Radicals; Hepatitis, Autoimmune; Horseradish Peroxidase; In Vitro Techniques; Lupus Erythematosus, Systemic; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Minocycline; Oxidation-Reduction; Peroxidase; Rats; Rats, Inbred BN; Tandem Mass Spectrometry

2009
Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats.
    PloS one, 2010, Aug-31, Volume: 5, Issue:8

    Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition; Conditioning, Psychological; Drug Synergism; Interleukin-1beta; Memory; Minocycline; Myelin Sheath; Perception; Rats; Rats, Sprague-Dawley; Task Performance and Analysis; Time Factors

2010
Mechanical integrity of hemodialysis catheters after exposure to a novel catheter lock solution.
    Infection control and hospital epidemiology, 2010, Volume: 31, Issue:11

    Topics: Acetylcysteine; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Catheters, Indwelling; Heparin; Humans; Infection Control; Minocycline; Renal Dialysis; Solutions; Tigecycline

2010
Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury.
    Experimental neurology, 2013, Volume: 249

    Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inflammation; Memory Disorders; Minocycline; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2013
Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes and modifies neuroinflammation in a rat model of mild traumatic brain injury.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018, Volume: 38, Issue:8

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Brain Injuries, Traumatic; Disease Models, Animal; Drug Synergism; Inflammation; Male; Minocycline; Oligodendroglia; Rats; Rats, Sprague-Dawley; Remyelination

2018
Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model.
    American journal of veterinary research, 2018, Volume: 79, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Collagenases; Cornea; Corneal Diseases; Disease Models, Animal; Dogs; Doxycycline; Edetic Acid; Horses; Matrix Metalloproteinase Inhibitors; Minocycline; Serum; Tetracycline

2018
Minocycline plus N-acetylcysteine protect oligodendrocytes when first dosed 12 hours after closed head injury in mice.
    Neuroscience letters, 2018, 08-24, Volume: 682

    Topics: Acetylcysteine; Animals; Corpus Callosum; Drug Therapy, Combination; Free Radical Scavengers; Head Injuries, Closed; Male; Mice; Mice, Inbred C57BL; Minocycline; Neuroprotection; Oligodendroglia; Time Factors

2018
Paclitaxel-induced HMGB1 release from macrophages and its implication for peripheral neuropathy in mice: Evidence for a neuroimmune crosstalk.
    Neuropharmacology, 2018, Volume: 141

    Topics: Acetylcysteine; Animals; Antibodies; Cells, Cultured; Clodronic Acid; Coculture Techniques; Ganglia, Spinal; HMGB1 Protein; Hyperalgesia; Imidazoles; Macrophages; Male; Membrane Proteins; Mice; Minocycline; Neurons; p300-CBP Transcription Factors; Paclitaxel; Peripheral Nervous System Diseases; Phosphoproteins; Phosphorylation; Proline; Pyridines; Pyruvates; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, CXCR4; Recombinant Proteins; Sciatic Nerve; Thiocarbamates; Thrombomodulin; Up-Regulation

2018
Antipsychotic-minocycline-acetylcysteine combination for positive, cognitive, and negative symptoms of schizophrenia.
    Asian journal of psychiatry, 2019, Volume: 40

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antipsychotic Agents; Drug Therapy, Combination; Free Radical Scavengers; Humans; Minocycline; Schizophrenia

2019
Delayed dosing of minocycline plus N-acetylcysteine reduces neurodegeneration in distal brain regions and restores spatial memory after experimental traumatic brain injury.
    Experimental neurology, 2021, Volume: 345

    Topics: Acetylcysteine; Animals; Brain; Brain Injuries, Traumatic; Drug Administration Schedule; Drug Therapy, Combination; Free Radical Scavengers; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Minocycline; Neurodegenerative Diseases; Neuroprotective Agents; Spatial Memory

2021
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats.
    Polish journal of veterinary sciences, 2022, Volume: 25, Issue:3

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Dexamethasone; Male; Matrix Metalloproteinase 9; Minocycline; Rats; Rats, Wistar; Reducing Agents; Ubiquinone; Vitamin E

2022