acetylcysteine and metyrapone

acetylcysteine has been researched along with metyrapone in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Birkett, DJ; Lelo, A; Miners, JO1
Kammerer, RC; Lampe, MA1
Smith, AG; Stewart, FP1
Pistelli, A; Salvemini, D; Vane, J1
Cantoni, O; Palomba, L; Sestili, P1

Reviews

1 review(s) available for acetylcysteine and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for acetylcysteine and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:8

    Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid

1990
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole

1987
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole

1986
Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Acetylcysteine; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Humans; In Vitro Techniques; Male; Metyrapone; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Proadifen; Rabbits; Sulfobromophthalein

1993
The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state.
    Free radical research, 1999, Volume: 31, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Buthionine Sulfoximine; Butylated Hydroxytoluene; Catalase; Cytochrome P-450 Enzyme Inhibitors; DNA Fragmentation; Drug Combinations; Drugs, Chinese Herbal; Electrophoresis, Agar Gel; Enzyme Inhibitors; Free Radical Scavengers; Glycyrrhiza; Humans; Hydrogen Peroxide; Iron Chelating Agents; Metyrapone; Oxidation-Reduction; Paeonia; Phenanthrolines; U937 Cells

1999