acetylcysteine and metallothionein

acetylcysteine has been researched along with metallothionein in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's7 (38.89)18.2507
2000's7 (38.89)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, HM; Cherian, MG; Tabarrok, R; Tamura, Y1
Kägi, JH; Pande, J; Vasák, M1
Ali, SF; Hussain, S; Slikker, W1
Gong, Q; Hart, BA1
Inoue, M; Kashiba, M; Kuroki, T; Nishikawa, M; Sato, EF; Utsumi, K1
Galdzicki, Z; Hanbauer, I; Rapoport, SI; Scortegagna, M1
Abe, T; Gotoh, S; Higashi, K; Kashimura, M; Yamamura, K1
Harvey, I; Li, H; Sadler, PJ; Sun, H1
Argentati, K; Bartozzi, B; Bernardini, G; Di Stasio, G; Donnini, A; Provinciali, M1
Suntres, ZE1
Huang, D; Liu, J; Song, G; Zhang, Y1
Aizu, T; Arima, Y; Hanada, K; Ikenaga, S; Kaneko, T; Matsuzaki, Y; Nakano, H; Tsuchida, S1
Baek, SH; Chung, HJ; Kim, JH; Kim, JR; Kim, SW; Kwun, WH; Lee, JH; Ryu, HH1
Bohrer, D; Brandão, R; Farina, M; Nogueira, CW; Rocha, JB; Santos, FW; Zeni, G1
Barchowsky, A; Leikauf, GD; Nemec, AA; Pitt, BR; Wasserloos, KJ1
Dubé, A; Harrisson, JF; Saint-Gelais, G; Séguin, C1
Hu, N; Jiang, S; Ren, J; Xiong, L; Yang, J; Yang, L; Zou, Y1
Costa, LM; Fiuza, Tda L; Mesquita, M; Oliveira, CS; Oliveira, VA; Pedroso, TF; Pereira, ME1

Reviews

1 review(s) available for acetylcysteine and metallothionein

ArticleYear
Role of antioxidants in paraquat toxicity.
    Toxicology, 2002, Oct-30, Volume: 180, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E

2002

Other Studies

17 other study(ies) available for acetylcysteine and metallothionein

ArticleYear
The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats.
    Chemico-biological interactions, 1992, Sep-28, Volume: 84, Issue:2

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Cytosol; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Metallothionein; Methionine Sulfoximine; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley; Sulfates; Vitamin K; Zinc; Zinc Sulfate

1992
Interaction of lysine residues with the metal thiolate clusters in metallothionein.
    Biochemistry, 1985, Nov-05, Volume: 24, Issue:23

    Topics: Acetylcysteine; Amino Acids; Animals; Cadmium; Circular Dichroism; Edetic Acid; Kinetics; Liver; Lysine; Metallothionein; Nitrobenzenes; Protein Conformation; Rats; Trinitrobenzenesulfonic Acid; Zinc

1985
Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection.
    Neurochemistry international, 1996, Volume: 29, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Cysteine; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Glutathione; Male; Metallothionein; Mice; Mice, Inbred C57BL; Nervous System Diseases; Nitrites; Superoxides

1996
Effect of thiols on cadmium-induced expression of metallothionein and other oxidant stress genes in rat lung epithelial cells.
    Toxicology, 1997, May-16, Volume: 119, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cadmium Chloride; Carcinogens; Cell Death; Cell Line; DNA Probes; Dose-Response Relationship, Drug; Epithelium; Gene Expression; Glutathione; Glutathione Transferase; Heme Oxygenase (Decyclizing); Kinetics; Lung; Metallothionein; Oxidoreductases; Rats; RNA, Messenger

1997
Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2

    Topics: Acetylcysteine; Adenosine Diphosphate; Animals; Cysteine; Digitonin; Dose-Response Relationship, Drug; Energy Metabolism; Glutathione; Liver Neoplasms, Experimental; Male; Mercaptoethanol; Metallothionein; Mitochondria; Nitric Oxide; Nitroso Compounds; Rats; Rats, Inbred Strains; S-Nitrosoglutathione; S-Nitrosothiols; Time Factors

1998
In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation.
    Brain research, 1998, Mar-23, Volume: 787, Issue:2

    Topics: Acetylcysteine; Animals; Astrocytes; Blotting, Western; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Free Radical Scavengers; Hydrogen Peroxide; Lead; Male; Metallothionein; Mice; Mice, Inbred C57BL; Oxidants; Oxidation-Reduction; Receptors, Glutamate; Stimulation, Chemical; Trisomy; Up-Regulation

1998
Concentration-dependent differential effects of N-acetyl-L-cysteine on the expression of HSP70 and metallothionein genes induced by cadmium in human amniotic cells.
    Biochimica et biophysica acta, 1998, Mar-12, Volume: 1380, Issue:1

    Topics: Acetylcysteine; Amnion; Cadmium; Cell Line; Dose-Response Relationship, Drug; Gene Expression; Glutathione; HSP70 Heat-Shock Proteins; Humans; Lipid Peroxidation; Metallothionein; RNA, Messenger

1998
Interactions of bismuth complexes with metallothionein(II).
    The Journal of biological chemistry, 1999, Oct-08, Volume: 274, Issue:41

    Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Binding, Competitive; Bismuth; Cadmium; Glutathione; Kinetics; Magnetic Resonance Spectroscopy; Metallothionein; Organometallic Compounds; Protein Binding; Rabbits; Spectrum Analysis; Zinc

1999
Reactive oxygen species modulate Zn(2+)-induced apoptosis in cancer cells.
    Free radical biology & medicine, 2002, Mar-01, Volume: 32, Issue:5

    Topics: Acetylcysteine; Adenocarcinoma; Animals; Apoptosis; Bacterial Proteins; Blotting, Western; Cell Division; Cell Survival; DNA Primers; Fas Ligand Protein; Free Radical Scavengers; Gene Expression; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Metallothionein; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Zinc

2002
Cadmium induced MTs synthesis via oxidative stress in yeast Saccharomyces cerevisiae.
    Molecular and cellular biochemistry, 2005, Volume: 280, Issue:1-2

    Topics: Acetylcysteine; Cadmium; Catalase; Cell Survival; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Metallothionein; Oxidative Stress; Saccharomyces cerevisiae; Superoxide Dismutase

2005
Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:1

    Topics: Acetylcysteine; Alkaloids; Benzophenanthridines; Blotting, Western; Enzyme Inhibitors; Epidermal Cells; Free Radical Scavengers; Genes, Reporter; Humans; Keratinocytes; Metallothionein; Monoterpenes; Phenanthridines; Plasmids; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Tropolone; Up-Regulation

2006
Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation.
    Experimental & molecular medicine, 2006, Apr-30, Volume: 38, Issue:2

    Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Adipose Tissue; Aged; Animals; Anti-Obesity Agents; Body Weight; Cell Differentiation; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Male; Metallothionein; Mice; Mice, Inbred C57BL; Middle Aged; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Time Factors; Viscera

2006
Antioxidants and metallothionein levels in mercury-treated mice.
    Cell biology and toxicology, 2006, Volume: 22, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Benzene Derivatives; Body Weight; Chelating Agents; Drug Therapy, Combination; Free Radical Scavengers; Injections, Subcutaneous; Kidney; Liver; Male; Mercuric Chloride; Mercury Poisoning; Metallothionein; Mice; Organoselenium Compounds; Porphobilinogen Synthase; Sulfhydryl Compounds; Unithiol; Urea

2006
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Bronchi; Cell Separation; Cells, Cultured; Chelating Agents; Chlorides; DNA-Binding Proteins; Epithelial Cells; Ethylamines; Flow Cytometry; Fluorescent Dyes; Humans; Metallothionein; Mice; Mice, Knockout; Nickel; Polycyclic Compounds; Pyridines; Pyrimidines; Reactive Oxygen Species; RNA, Messenger; Time Factors; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Zinc Compounds

2009
Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:6

    Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Hypoxia; Chlorides; Chromosome Mapping; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genes, Reporter; HEK293 Cells; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Luciferases; Metallothionein; Methacrylates; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Stability; Rotenone; Signal Transduction; Thiazoles; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Zinc Compounds

2011
Heavy metal scavenger metallothionein attenuates ER stress-induced myocardial contractile anomalies: role of autophagy.
    Toxicology letters, 2014, Mar-21, Volume: 225, Issue:3

    Topics: Acetylcysteine; Adenine; Animals; Autophagy; Echocardiography; Endoplasmic Reticulum Stress; Heart; Male; Metallothionein; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Tunicamycin

2014
Zinc and N-acetylcysteine modify mercury distribution and promote increase in hepatic metallothionein levels.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 32

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatinine; Female; Kidney; Liver; Mercury; Metallothionein; Porphobilinogen Synthase; Rats, Wistar; Sulfhydryl Compounds; Urea; Zinc

2015