acetylcysteine and mesna

acetylcysteine has been researched along with mesna in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199012 (32.43)18.7374
1990's10 (27.03)18.2507
2000's5 (13.51)29.6817
2010's9 (24.32)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gobert, JG; Risack, LE; Vandevelde, ME1
Fournier, AM; Timon-David, P; Vanelle, P1
Einhorn, LH; Langefeld, C; Loehrer, PJ; Munshi, NC; Neuman, A; Nichols, CR; Roth, BJ; Sledge, G; Walsh, WB; Williams, SD1
Einhorn, LH; Loehrer, PJ; Munshi, N; Williams, SD1
Katterjohn, CJ; Pearce, HL; Rinzel, SM; Seitz, DE1
Alfredsson, H; Malmborg, AS; Strandvik, B1
Hilgard, P; Pohl, J1
Dietzsch, HJ; Pilz, U; Wichmann, G1
Czarnomska, A; Czyzewska-Szafran, H; Danysz, A; Jastrzebski, Z1
Konrádová, V; Sulová, J; Vávrová, V1
Ohno, Y; Ormstad, K1
Ovchinnikov, AA; Rabicheva, MI; Vaĭsberg, LA1
Janota, J; Konrádová, V; Vávrová, V1
Berrigan, MJ; Gurtoo, HL; Marinello, AJ; Pavelic, Z; Struck, RF; Williams, CJ1
Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Lebegue, N; Luyckx, M1
Beyersbergen van Henegouwen, GM; van den Broeke, LT1
Benjamin, RS; Legha, SS; Nicaise, C; Patel, SR1
Brunet, C; Cabanis, A; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Lebegue, S; Luyckx, M1
Furukawa, F; Hasegawa, R; Inoue, T; Kurokawa, Y; Nishikawa, A; Sai-Kato, K; Toyokuni, S; Uchida, K; Umemura, T1
Portel, L; Taytard, A; Tunon de Lara, JM; Vernejoux, JM; Weiss, I1
Averill, DA; Lord-Fontaine, S1
Csako, G1
Cao, D; Grdina, DJ; Kataoka, Y; Li, JJ; Murley, JS; Oberley, LW1
Hur, GM; Kim, YH; Lee, CJ; Lee, JH; Park, JS; Seok, JH; Seol, IC1
Castegnaro, M; Faucet-Marquis, V; Pfohl-Leszkowicz, A; Pont, F; Rizk, T; Størmer, FC1
Civelli, M; Facchinetti, F; Moretto, N; Patacchini, R; Singh, D; Southworth, T1
Sajewicz, W1
Chen, N; Hanly, L; Koren, G; Rieder, M; Yeger, H1
Nikiteas, N; Perrea, D; Tsigris, C; Yiannakopoulou, E1
Beltran, J; Blasi, A; Caballo, C; Escolar, G; Galán, AM; Lozano, M; Taura, P1
Grdina, DJ; Miller, RC; Murley, JS1
Arai, T; Kitamura, D; Koyama, R; Mizuta, R; Yuasa, M1
Button, BM; Holland, AE; Le Maitre, C; Romero, L; Steward, R; Tarrant, BJ; Thompson, BR1
Boskabadi, J; Salehifar, E; Yousefi-Mazhin, E1

Reviews

4 review(s) available for acetylcysteine and mesna

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Single-agent ifosfamide studies in sarcomas of soft tissue and bone: the M.D. Anderson experience.
    Cancer chemotherapy and pharmacology, 1993, Volume: 31 Suppl 2

    Topics: Acetylcysteine; Bone Neoplasms; Fluid Therapy; Humans; Ifosfamide; Mesna; Randomized Controlled Trials as Topic; Sarcoma; Soft Tissue Neoplasms; Treatment Outcome; Urinary Bladder Diseases

1993
Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2012, Volume: 22, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Erythromycin; Humans; Laparoscopy; Melatonin; Mesna; Oxidative Stress; Pentoxifylline; Pneumoperitoneum, Artificial; Rabbits; Rats; Verapamil; Zinc Compounds

2012
Mucoactive agents for chronic, non-cystic fibrosis lung disease: A systematic review and meta-analysis.
    Respirology (Carlton, Vic.), 2017, Volume: 22, Issue:6

    Topics: Acetylcysteine; Administration, Inhalation; Bronchiectasis; Chronic Disease; Deoxyribonuclease I; Expectorants; Forced Expiratory Volume; Humans; Lung Diseases; Mannitol; Mesna; Mucociliary Clearance; Quality of Life; Recombinant Proteins; Saline Solution, Hypertonic; Symptom Flare Up; Vital Capacity

2017

Other Studies

33 other study(ies) available for acetylcysteine and mesna

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of thiol derivatives on mixed mucus and blood clots in vitro.
    Resuscitation, 1978, Volume: 6, Issue:1

    Topics: Acetylcysteine; Blood Coagulation; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Mercaptoethanol; Mesna; Mucus; Respiratory System; Saline Solution, Hypertonic

1978
[Double contrast studies of the colon. Use of acetyl-cystein or mucofluid? (author's transl)].
    Journal de radiologie, 1979, Volume: 60, Issue:12

    Topics: Acetylcysteine; Colon; Contrast Media; Costs and Cost Analysis; Humans; Mercaptoethanol; Mesna; Radiography

1979
Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors.
    Investigational new drugs, 1992, Volume: 10, Issue:3

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dysgerminoma; Etoposide; Hematuria; Humans; Ifosfamide; Male; Mesna; Severity of Illness Index; Vinblastine

1992
Cyclophosphamide and ifosfamide: role of uroprotective agents.
    Cancer investigation, 1990, Volume: 8, Issue:2

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Hematuria; Humans; Ifosfamide; Mercaptoethanol; Mesna; Urogenital Neoplasms

1990
Thermodynamic analysis of the reaction of phosphoramide mustard with protector thiols.
    Cancer research, 1989, Jul-01, Volume: 49, Issue:13

    Topics: Acetylcysteine; Alkylation; Animals; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; In Vitro Techniques; Mesna; Phosphoramide Mustards; Sulfhydryl Compounds; Thermodynamics

1989
N-acetylcysteine and 2-mercaptoethane sulphonate inhibit anti-pseudomonas activity of antibiotics in vitro.
    European journal of respiratory diseases, 1987, Volume: 70, Issue:4

    Topics: Acetylcysteine; Anti-Bacterial Agents; Drug Interactions; Mercaptoethanol; Mesna; Microbial Sensitivity Tests; Pseudomonas aeruginosa

1987
Cause and prevention of mafosfamide-induced venous pain.
    Investigational new drugs, 1986, Volume: 4, Issue:4

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cyclophosphamide; Mesna; Pain; Rats; Veins

1986
[Effect of mucolytic agents on various antibiotics].
    Kinderarztliche Praxis, 1987, Volume: 55, Issue:5

    Topics: Acetylcysteine; Anti-Bacterial Agents; Child; Dose-Response Relationship, Drug; Humans; Mercaptoethanol; Mesna; Pseudomonas aeruginosa

1987
The effect of sodium-2-mercaptoethane-sulphonate, N-acetylcysteine and cysteine on the uptake of cytosine arabinoside by normal and neoplastic thymus cells of mice.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine; Cytarabine; Female; Male; Mercaptoethanol; Mesna; Mice; Thymus Gland; Thymus Neoplasms; Tumor Cells, Cultured

1988
Comparison of the effect of three oral mucolytics on the ultrastructure of the tracheal epithelium in rabbits.
    Respiration; international review of thoracic diseases, 1985, Volume: 48, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Animals; Carbocysteine; Epithelium; Expectorants; Mercaptoethanol; Mesna; Rabbits; Time Factors; Trachea

1985
N-acetylcysteine and sodium 2-mercaptoethane sulfonate as sources of urinary thiol groups in the rat.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Acetylcysteine; Animals; Intestinal Mucosa; Kidney; Kinetics; Liver; Lung; Male; Mercaptoethanol; Mesna; Myocardium; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Tissue Distribution

1984
[Comparative effectiveness of various methods of bronchoscopic sanation in chronic nonspecific lung diseases].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:3

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Bronchoscopy; Evaluation Studies as Topic; Expectorants; Furagin; Humans; Lung Diseases; Mesna; Middle Aged; Sodium Chloride; Therapeutic Irrigation

1980
Comparison of the effect of aerosols of four mucolytic solutions on the ultrastructure of the tracheal epithelium in rabbits.
    Respiration; international review of thoracic diseases, 1982, Volume: 43, Issue:1

    Topics: Acetylcysteine; Aerosols; Animals; Drug Combinations; Epithelium; Expectorants; Mesna; Propylene Glycols; Rabbits; Time Factors; Trachea

1982
Protective role of thiols in cyclophosphamide-induced urotoxicity and depression of hepatic drug metabolism.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Acetylcysteine; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Cyclophosphamide; Cytochrome P-450 Enzyme System; Leukopenia; Liver; Male; Mercaptoethanol; Mesna; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Rats; Rats, Inbred Strains; Urinary Bladder

1982
Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs.
    Pharmacy world & science : PWS, 1995, May-26, Volume: 17, Issue:3

    Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Expectorants; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Hypochlorous Acid; Mesna; Reactive Oxygen Species; Respiratory Burst; Superoxides; Thiazoles; Thiazolidines

1995
UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo.
    International journal of radiation biology, 1993, Volume: 63, Issue:4

    Topics: Acetylcysteine; Animals; Captopril; Chlorpromazine; Cysteamine; Epidermis; Ergothioneine; Female; Mesna; Methoxsalen; Penicillamine; Radiation-Protective Agents; Rats; Rats, Wistar; Sulfhydryl Compounds; Tiopronin; Ultraviolet Rays

1993
Comparison of in vitro effects of two thiol-containing drugs on human neutrophils hydrogen peroxide production.
    Methods and findings in experimental and clinical pharmacology, 1993, Volume: 15, Issue:2

    Topics: Acetylcysteine; Humans; Hydrogen Peroxide; Mesna; Neutrophils; Oxidation-Reduction

1993
Prevention by 2-mercaptoethane sulfonate and N-acetylcysteine of renal oxidative damage in rats treated with ferric nitrilotriacetate.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Antioxidants; Carcinogens; Deoxyguanosine; DNA; DNA Damage; Ferric Compounds; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Mesna; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

1996
[Osmolarity of solutions used in nebulization].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:2

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Albuterol; Anti-Asthmatic Agents; Bicarbonates; Bronchial Diseases; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agents; Buffers; Chemical Phenomena; Chemistry, Physical; Cromolyn Sodium; Expectorants; Gentamicins; Humans; Hypertonic Solutions; Ipratropium; Isotonic Solutions; Mesna; Nebulizers and Vaporizers; Netilmicin; Oils, Volatile; Osmolar Concentration; Sodium Chloride; Terbutaline; Terpenes

1998
Enhancement of cytotoxicity of hydrogen peroxide by hyperthermia in chinese hamster ovary cells: role of antioxidant defenses.
    Archives of biochemistry and biophysics, 1999, Mar-15, Volume: 363, Issue:2

    Topics: Acetylcysteine; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Glutathione; Hot Temperature; Hydrogen Peroxide; Intracellular Fluid; Mesna; Oxidation-Reduction; Protective Agents; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1999
Mesna and other free-sulfhydryl compounds produce false-positive results in a urine test strip method for ascorbic acid.
    Clinical chemistry, 1999, Volume: 45, Issue:12

    Topics: Acetylcysteine; Ascorbic Acid; Captopril; False Positive Reactions; Humans; Mesna; Reagent Strips

1999
Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.
    Radiation research, 2004, Volume: 162, Issue:5

    Topics: Acetylcysteine; Amifostine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Cell Line, Tumor; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; I-kappa B Proteins; Mercaptoethylamines; Mesna; Mice; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Plasmids; Protective Agents; Radiation-Protective Agents; Serine; Sulfhydryl Compounds; Superoxide Dismutase; Time Factors; Transfection

2004
Effects of ursolic acid, betulin and sulfur-containing compounds on mucin release from airway goblet cells.
    Planta medica, 2004, Volume: 70, Issue:12

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betula; Cornus; Cricetinae; Dose-Response Relationship, Drug; Goblet Cells; Male; Mesna; Mesocricetus; Mucins; Phytotherapy; Trachea; Triterpenes; Ursolic Acid

2004
Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA-adduct formation.
    Molecular nutrition & food research, 2006, Volume: 50, Issue:6

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chlorine; Chromatography, High Pressure Liquid; DNA Adducts; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glutathione Synthase; Isoxazoles; Kidney; Mesna; Ochratoxins; Opossums; Oxidative Stress; Spectrometry, Mass, Electrospray Ionization

2006
alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:5

    Topics: Acetylcysteine; Aged; Aldehydes; Cell Survival; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Humans; Interleukin-8; Lung; Macrophages; Male; Mesna; Middle Aged; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Smoking

2009
Effect of thiol drugs on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocytes, erythrocyte lysate, and erythrocyte membranes.
    Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2

    Topics: Acetylcysteine; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Luminescence; Luminol; Mesna; Models, Biological; Oxidative Stress; Penicillamine; Sulfhydryl Compounds; tert-Butylhydroperoxide; Tiopronin

2010
The effect of N-acetylcysteine on the antitumor activity of ifosfamide.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Ifosfamide; Mesna; Neuroblastoma; Phosphoramide Mustards; Rhabdomyosarcoma

2011
The addition of MESNA in vitro prolongs prothrombin time similar to N-acetyl cysteine.
    Clinical chemistry and laboratory medicine, 2013, Volume: 51, Issue:12

    Topics: Acetylcysteine; Blood Coagulation; Humans; Mesna; Prothrombin Time; Time Factors

2013
Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs.
    Radiation research, 2014, Volume: 181, Issue:5

    Topics: Acetylcysteine; Acute Radiation Syndrome; Amifostine; Animals; Captopril; Cell Line, Transformed; Cell Line, Tumor; Cells, Cultured; Colony-Forming Units Assay; Drug Evaluation, Preclinical; Drug Synergism; Endothelial Cells; Fibroblasts; Free Radical Scavengers; Humans; Mesna; Metformin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Radiation Injuries, Experimental; Radiation-Protective Agents; Sarcoma; Sulfhydryl Compounds

2014
Acrolein, a highly toxic aldehyde generated under oxidative stress in vivo, aggravates the mouse liver damage after acetaminophen overdose.
    Biomedical research (Tokyo, Japan), 2014, Volume: 35, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acrolein; Animals; Blotting, Western; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Drug Overdose; Liver; Mesna; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2014
Ifosfamide-induced acute kidney injury in a patient with leiomyosarcoma: A case report.
    Cancer reports (Hoboken, N.J.), 2022, Volume: 5, Issue:10

    Topics: Acetylcysteine; Acute Kidney Injury; Creatinine; Female; Humans; Ifosfamide; Leiomyosarcoma; Mesna; Urea

2022