acetylcysteine and mesalamine

acetylcysteine has been researched along with mesalamine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ancha, H; Harty, RF; Lightfoot, S; Siddiqui, A; Stewart, CA; Tedesco, D1
Arriaza, E; Castillejo, MS; Delgado, M; Gisbert, JP; Gonzalez Lara, V; Guijarro, LG; Marin-Jimenez, I; Mate, J; Olleros, T; Pena, AS; Perez-Calle, JL; Prieto-Merino, D1
Ancha, HR; Harty, RF; Kurella, RR; Lightfoot, S; McKimmey, CC1
Behnen, M; Hermann, E; Kirchner, T; Klinger, M; Laskay, T; Möller, S; Solbach, W1

Reviews

1 review(s) available for acetylcysteine and mesalamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetylcysteine and mesalamine

ArticleYear
N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: randomized, placebo-controlled pilot study.
    World journal of gastroenterology, 2008, May-14, Volume: 14, Issue:18

    Topics: Acetylcysteine; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Colitis, Ulcerative; Drug Therapy, Combination; Female; Free Radical Scavengers; Glutathione; Humans; Interleukin-6; Interleukin-8; Male; Mesalamine; Middle Aged; Pilot Projects; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2008

Other Studies

6 other study(ies) available for acetylcysteine and mesalamine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Antioxidant therapy with N-acetylcysteine plus mesalamine accelerates mucosal healing in a rodent model of colitis.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:4

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biopsy, Needle; Colitis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Immunohistochemistry; Inflammation Mediators; Male; Mesalamine; Peroxidase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity

2006
Effects of N-acetylcysteine plus mesalamine on prostaglandin synthesis and nitric oxide generation in TNBS-induced colitis in rats.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:4

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Therapy, Combination; Free Radical Scavengers; Intestinal Mucosa; Male; Membrane Proteins; Mesalamine; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid

2009
Flavonoids and 5-aminosalicylic acid inhibit the formation of neutrophil extracellular traps.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cells, Cultured; Chemotaxis, Leukocyte; Flavonoids; Humans; Mesalamine; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2013